• Journal of Gastric Cancer
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• 제18권3호
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• pp.296-304
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• 2018

Purpose: This study aimed to examine the outcomes of cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) in patients with peritoneal metastasis (PM) of advanced gastric cancer (AGC). Materials and Methods: Between May 2015 and June 2017, 38 CRS and HIPEC procedures were performed in patients with PM of AGC at the Dankook University Hospital. We prospectively collected and analyzed data regarding PM grade, morbidity and mortality rates, and short-term follow-up results (median, 13.5 months). Results: The mean peritoneal cancer index was 15 (range, 0-39). Complete cytoreduction was achieved in 21 patients (55.2%), whereas complications occurred in 16 (42.1%) and 2 (5.7%) patients died. The overall median patient survival time was 19 months. The patients who underwent complete cytoreduction had a median survival time of 26 months, which was significantly longer than the median survival time of 16 months in the patients who did not undergo complete cytoreduction (P=0.006). Conclusions: CRS with HIPEC may have a beneficial effect in patients with PM of AGC. However, the rates of complications and mortality associated with this combined therapeutic approach are high. Therefore, this treatment should be performed only in selected patients by surgeons experienced in the field of gastric cancer with PM.

• 한국해양환경ㆍ에너지학회지
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• 제8권1호
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• pp.23-30
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• 2005

특정 해역에 부방파제를 설치하는 경우 예상되는 정온도의 평가를 위한 수치해법을 제안하고, 이를 바탕으로 마산 부근의 원전항에 설치예정인 부방파제의 효과를 검토하였다. 수치모형은 항 내 정온도를 평가하는 데 널리 사용되는 완경사 방정식을 이용하였고 산란 항을 도입하여 부방파제와 같은 폭이 얇은 구조물에 의한 산란 파를 반영하도록 하였다. 부방파제의 도입이 결정된 동방파제의 효과를 수치모의 하였고, 착저식으로 하는 경우와 비교하였다. 부방파제의 부분투과 등 구조물이 파랑에 미치는 영향을 적극적으로 고려하는 본 수치해법은 부방파제 효과의 정량적 평가에 효율적으로 활용될 수 있다.

• Smart Structures and Systems
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• 제9권1호
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• pp.1-20
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• 2012

In bridge engineering, maintenance strategies and thus budgetary demands are highly influenced by construction type and quality of design. Nowadays bridge owners and planners tend to include life-cycle cost analyses in their decision processes regarding the overall design trying to optimize structural reliability and durability within financial constraints. Smart permanent and short term monitoring can reduce the associated risk of new design concepts by observing the performance of structural components during prescribed time periods. The objectives of this paper are the discussion and analysis of influence line or influence field approaches in terms of (a) an efficient incorporation of monitoring information in the structural performance assessment, (b) an efficient characterization of performance indicators for the assessment of structures, (c) the ability of optimizing the positions of sensors of a monitoring system, and (d) the ability of checking the robustness of the monitoring systems applied to a structure. The proposed influence line- model correction approach has been applied to an integrative monitoring system that has been installed for the performance assessment of an existing three-span jointless bridge.

• Journal of Yeungnam Medical Science
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• 제21권1호
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• pp.12-22
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• 2004

The management of coincident glaucoma and cataract is not only a common clinical challenge but also an important research topic in the ophthalmic surgical field. The purpose of this article is to compare the different surgical options on the basis of their achievable postoperative intraocular pressure (IOP) control, success rates, and complication rates reported in the related literature, and to give advice on how to manage typical situations of patients with both glaucoma and cataract. Main topics were focused on indications and rationale of 3 surgical options (only cataract surgery first and later trabeculectomy, only trabeculectomy first and later cataract surgery, or simultaneous combined surgery). Modern clear corneal cataract extraction techniques resulted in a modest intermediate-term reduction of IOP and has considerably improved the success rates of combined glaucoma and cataract surgery. It also enabled future trabeculectomy to be successfully performed at a later date if necessary. Trabeculectomy alone achieved better IOP regulation than phacotrabeculectomy (combined surgery), but subsequent cataract surgery may compromise preexisting filtering bleb. Combined surgery augmented with mitomycin C achieved a lower IOP than combined surgery alone but had a higher complication rate. In conclusion, the choice of the preferred surgical method should be determined according to the target pressure, the amount of glaucomatous damage, and the grade of visual disturbance caused by the cataract. Phacotrabeculectomy with adjunctive mitomycin C offers visual improvement and achieves the best IOP lowering of all types of combined glaucoma and cataract surgery currently used but is associated with potentially sight-threatening complications.

• Clinical and Experimental Pediatrics
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• 제53권12호
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• pp.989-993
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• 2010

Although numerous clinical observational studies have been conducted over a period of over 30 years, the clinical significance of $Ureaplasma$ infection is still under debate. The $Ureaplasma$ speices. is a commensal in the female genital tract and considered to have of low virulence; however, $Ureaplasma$ colonization has been associated with infertility, stillbirth, preterm delivery, histologic chorioamnionitis, and neonatal morbidities, including congenital pneumonia, meningitis, bronchopulmonary dysplasia, and perinatal death. Recently, $Ureaplasma$ was subdivided into 2 separate species and 14 serovars. $Ureaplasma$ $parvum$ is known as biovar 1 and contains serovars 1, 3, 6, and 14, and $Ureaplasma$ $urealyticum$ (biovar 2) contains the remaining serovars (2, 4, 5, and 7-13). The existence of differences in pathogenicities of these 14 serovars and 2 biovars is controversial. Although macrolides are the only antimicrobial agents currently available for use in neonatal ureaplasmal infections, in the current clinical field, it is difficult to make decisions regarding which antibiotics should be used. Future investigations involving large, multicenter, randomized, controlled studies are needed before proper recommendations can be made for clinical practice.

• 한국지반공학회:학술대회논문집
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• 한국지반공학회 2002년도 봄 학술발표회 논문집
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• pp.627-634
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• 2002

To facilitate a drilling plan for grouting in fractured rock, an algorithm of practical use associated with a new term “fracture density distribution”or“fracture tomogram”is developed. It is well known that Televiewer data(amplitude and traveltime image) provide detailed information about not only dip and dip direction of each fracture but also its aperture size estimated by an appropriate evaluation algorithm. A selected plane section of medium around a borehole or the cross section between two boreholes is discretized into a two dimensional grid of cells(rectangular elements). As each elongated(straight) fracture passes through the cells, the corresponding aperture size value is successively summed up in each cell, depending on the fracture length segment. In this, the fracture lines can be determined by intersecting of each fracture plane with the selected plane section. If the fracture line does not pass through a particular grid element, the segment length is set to zero. The final value(aperture size value of each cell) derived from all the detected fractures constitutes the fracture density distribution of the selected plane section, Field examples are illustrated, which will prove the benefit of the suggested algorithm for several kinds of grouting works.

• Smart Structures and Systems
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• 제4권6호
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• pp.741-757
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• 2008

The research field of structural control has evolved from the development of passive devices since 1970s, through the intensive investigation on active systems in 1980s, to the recent studies of semi-active control systems in 1990s. Currently semi-active control is considered most promising in civil engineering applications. However, actual implementation of semi-active devices is still limited due mainly to their system maintenance and associated long-term reliability as a result of power requirement. In this paper, the concept of functionally upgraded passive devices is introduced to streamline some of the state-of-the-art researches and guide the development of new passive devices that can mimic the function of their corresponding semi-active control devices for various applications. The general characteristics of this special group of passive devices are discussed and representative examples are summarized. Their superior performances are illustrated with cyclic and shake table tests of two example devices: mass-variable tuned liquid damper and friction-pendulum bearing with a variable sliding surface curvature.

• 한국멀티미디어학회논문지
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• 제25권9호
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• pp.1257-1265
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• 2022

Recognition of sign language is challenging due to the occlusion of hands, accuracy of hand gestures, and high computational costs. In recent years, deep learning techniques have made significant advances in this field. Although these methods are larger and more complex, they cannot manage long-term sequential data and lack the ability to capture useful information through efficient information processing with faster convergence. In order to overcome these challenges, we propose a word-level sign language recognition (SLR) system that combines a real-time human pose detection library with the minimized version of the gated recurrent unit (GRU) model. Each gate unit is optimized by discarding the depth-weighted reset gate in GRU cells and considering only current input. Furthermore, we use sigmoid rather than hyperbolic tangent activation in standard GRUs due to performance loss associated with the former in deeper networks. Experimental results demonstrate that our pose-based optimized GRU (Pose-OGRU) outperforms the standard GRU model in terms of prediction accuracy, convergency, and information processing capability.

• Radiation Oncology Journal
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• 제30권4호
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• pp.153-157
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• 2012

Purpose: There has been no definite consensus on standard treatment, either local or systemic, for the Kaposi's sarcoma (KS). Radiotherapy (RT) can be a good local therapeutic choice especially in non-AIDS associated KS (NAKS) for its indolent behavior. Materials and Methods: Medical records of 17 KS patients treated with RT at the Seoul National University Hospital from February 1998 to January 2012 were retrospectively reviewed. One human immunodeficiency virus (HIV)+ patient with 3 lesions was excluded. The total number of the lesion was 23 among the 16 patients. The median follow-up period was 27.9 months. Correlation between response and variables was analyzed using the logistic regression model. Median age of the patients was 75 years. All the 23 lesions were located at the extremities. Fourteen (61%) of those had pain or local swelling as the initial presentation. Ten patients had possible causes of immunodeficiency and were regarded as iatrogenic, and other 6 were classic KS. Median dose of RT was 36 Gy. Results: No KS-related death was observed. Excluding 2 with short-term follow-up only, complete response and partial response were obtained in 2 (9%) and 19 (73%) lesions, respectively. Of those, 3 lesions underwent local progression. Six had out-of-field recurrence after RT. Symptom improvement was achieved in 13 (93%) of 14 patients. Grade 2 skin toxicities were found in 9 lesions but all got improvement after treatment. When divided into responsive and progressive group, free from progression was not related to any of the possible variables. Conclusion: RT is effective in local control of NAKS resulting great response rate.

• 천문학논총
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• 제31권3호
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• pp.57-63
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• 2016

We summarize our preliminary study on the research cooperation method in the astronomy field between Republic of Korea (South Korea) and Democratic People's Republic of Korea (North Korea). To investigate the recent astronomical activities of North Korea, we have surveyed the published records of research papers and international collaborations associated with North Korean astronomers. We found only 4 astronomical papers among the identified 260 SCI papers related to North Korean researchers for the past 11 years. North Korean astronomers had very few interactions with the international astronomical society before rejoining IAU in 2012. Recently, North Korea made several astronomical research exchanges with China and Netherlands. They seemed to attend several international conferences and present their research results. We have studied possibilities to establish international networks to encourage the cooperation between South and North, and suggest to start collaboration in the historical astronomy. The collaboration can be expanded gradually to other fields in astronomy. There are many obvious political difficulties to have interactions with North Koreans. However, it will be necessary to make a long-term plan considering the reunification.