• Journal of Information Processing Systems
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• v.19 no.2
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• pp.219-231
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• 2023

Intelligent applications are crucial for increasing the popularity of shared urban electric bicycles (EBs). Building an application platform architectural system that can satisfy independent user operations is critical for increasing the intelligent usage of shared EBs. Consequently, we collected online reviews of shared EB applications, conducted semantic processing and sentiment analysis, and refined the positive and negative review data for each function. The positive and negative review indices of each function were calculated using the formulae for positive and negative review indices of product functions, thereby determining the functions that need to be improved. Each function of the Shared EB application was improved according to its business process. The main contributions of this study are to build a user requirement architecture system for the Shared EB application with five dimensions and 22 functions using the Delphi method to design the user interface (UI) of this application based on user satisfaction evaluation results; to create a high-fidelity dynamic interaction prototype and compare user satisfaction before and after improving the Shared EB application functions. The testing results indicate that the changes in the UI significantly improve the user experience satisfaction of the urban Shared EB application, with the positive experience index increasing by 69.21% and the negative experience index decreasing by 75.85% overall. This information can be directly used by relevant companies to improve the functions of the Shared EB application.

• Dementia and Neurocognitive Disorders
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• v.21 no.1
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• pp.1-16
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• 2022

Background and purpose: We investigated existing nonpharmacological programs for people with dementia (PWD) to explore critical factors related to the effectiveness of these types of programs. Methods: We conducted a qualitative systematic literature review to identify nonpharmacological intervention programs developed for PWD and reviewed 36 randomized controlled trials. Among several outcomes reported in each study, we focused on the most common outcomes including quality of life (QoL), neuropsychiatric symptoms, depression, agitation, and cognition for further review. Results: Several factors were identified that might affect the outcomes of nonpharmacological interventions for PWD including study design, characteristics of the intervention, maintaining research participants, heterogeneity issues, and implementation fidelity. About half of studies in this review reported positive program effects on their targeted outcomes such as Well-being and Health for PWD on improving quality of life, neuropsychiatric symptoms and agitation; cognitive stimulation therapy on QoL, neuropsychiatric symptoms and cognition; and a stepwise multicomponent intervention on neuropsychiatric symptoms, depression and agitation. Conclusions: We found some programs even with a rigorous study design did not produce expected outcomes while other programs with poor designs reported positive outcomes, which necessitates further investigation on the validity of the assessments. Factors such as individual tailored and customized interventions, promoting social interactions, ease of administration and compatibility of interventions, and developing program theory need to be considered when developing nonpharmacological intervention programs.

• Journal of Korean Medicine Rehabilitation
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• v.24 no.4
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• pp.83-96
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• 2014

Objectives Although many studies explored the topic of meridian sinew in various perspectives and the term "meridian sinew" is widely used, the theory of meridian sinew is not applied for precise diagnosis and in-depth treatment in clinical practice. The aim of the study is to provide basic data classifying muscles into meridian sinew for future studies that investigate meridian sinew based on an anatomical basis. Methods Studies were identified with searches of six major Korean databases: OASIS, KoreaMed, KMBASE, KISS, NDSL and KoreanTK. Published primary studies classifying muscles into meridian sinew were included. Results A total of 20 studies met the inclusion criteria and were included in the analysis. Twelve studies conducted the classification of muscles into meridian sinew based on meridian/ acupoints distribution and six based on meridian sinew distribution, and two based on both. Muscles with fidelity level of 50 or more were 54 (85.7%) and muscles with 100 fidelity level were 7 (11.3%): occipitalis, adductor digiti minimi, frontalis, biceps femoris, rectus femoris, vatus lateralis and extensor digitorum longus. Conclusions Classification results of muscles into meridian sinew varied according to the classification criteria and interpretation of meridian sinew and acupoints distribution. To develop muscle sinew as a more useful theory in diagnosis and treatment, efforts should be made to reduce the gap between study results and build consensus on the anatomical entity of meridian sinew.

• BMB Reports
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• v.48 no.8
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• pp.454-460
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• 2015

Naturally occurring reoviruses are live replication-proficient viruses that specifically infect human cancer cells while sparing their normal counterpart. Since the discovery of reoviruses in 1950s, they have shown various degrees of safety and efficacy in pre-clinical or clinical applications for human anti-cancer therapeutics. I have recently discovered that cellular tumor suppressor genes are also important in determining reoviral tropism. Carcinogenesis is a multi-step process involving the accumulation of both oncogene and tumor suppressor gene abnormalities. Reoviruses can exploit abnormal cellular tumor suppressor signaling for their oncolytic specificity and efficacy. Many tumor suppressor genes such as p53, ataxia telangiectasia mutated (ATM), and retinoblastoma associated (RB) are known to play important roles in genomic fidelity/maintenance. Thus, a tumor suppressor gene abnormality could affect host genomic integrity and likely disrupt intact antiviral networks due to the accumulation of genetic defects which in turn could result in oncolytic reovirus susceptibility. This review outlines the discovery of oncolytic reovirus strains, recent progresses in elucidating the molecular connection between oncogene/tumor suppressor gene abnormalities and reoviral oncotropism, and their clinical implications. Future directions in the utility of reovirus virotherapy is also proposed in this review. [BMB Reports 2015; 48(8): 454-460]

• Journal of Sensor Science and Technology
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• v.32 no.6
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• pp.340-351
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• 2023

Wearable sensors designed for strain, pressure, and temperature measurements are essential for monitoring human movements, health status, physiological data, and responses to external stimuli. Notably, recent research has led to the development of high-performance wearable sensors using innovative materials and device structures that exhibit ultra-high sensitivity compared with their commercial counterparts. However, the quest for accurate sensing has identified a critical challenge. Specifically, the mechanical flexibility of the substrates in wearable sensors can introduce interference signals, particularly when subjected to varying external stimuli and environmental conditions, potentially resulting in signal crosstalk and compromised data fidelity. Consequently, the pursuit of non-interference sensing technology is pivotal for enabling independent measurements of concurrent input signals related to strain, pressure, and temperature, ensuring precise signal acquisition. In this comprehensive review, we present an overview of the recent advances in noninterference sensing strategies. We explore various fabrication methods for sensing strain, pressure, and temperature, emphasizing the use of hybrid composite materials with distinct mechanical properties. This review contributes to the understanding of critical developments in wearable sensor technology that are vital for their ongoing application and evolution in numerous fields.

• Molecules and Cells
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• v.27 no.1
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• pp.1-3
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• 2009

Mitotic spindle mediates the segregation of chromosomes in the cell cycle and the proper function of the spindle is crucial to the high fidelity of chromosome segregation and to the stability of the genome. Nucleation of microtubules (MTs) from centrosomes and chromatin represents two well-characterized pathways essential for the assembly of a dynamic spindle in mitosis. Recently, we identified a third MT nucleation pathway, in which existing MTs in the spindle act as a template to promote the nucleation and polymerization of MTs, thereby efficiently amplifying MTs in the spindle. We will review here our current understanding on the molecular mechanism, the physiological function and the cell-cycle regulation of MT amplification.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.4
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• pp.525-537
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• 2020

This study aimed to determine the current state and characteristics of simulation-based operating processes in nursing education based on the Jeffries theoretical framework in South Korea by taking an integrated look at study findings in order to provide a scientific basis for future simulation-based operating processes. We searched eight databases, including the Korea Education and Research Information Service, National Library, Korean Studies Information Service System, National Digital Science Library, Korea Institute of Science and Technology Information, KOREAMED, and Korean Medical Database, using terms "simulation" and "nursing" as keywords in November 2017 in the Korean language. Sixteen studies were identified, reviewed, and appraised in this integrative review. The literature was categorized into these themes: general study characteristics, operation method, teaching and learning methods, subject characteristics, outcome variables, and theoretical framework. The simulation processes in nursing education in South Korea that were analyzed in this study did not fully reflect the main concepts suggested in the NLN Jeffries simulation framework. Thus, simulation program developers need to consider and incorporate a variety of strategies, based on the identification of essential components, to improve simulation effectiveness.

• Korean Journal of School Psychology
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• v.17 no.3
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• pp.401-419
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• 2020

The purpose of this study was to validate the Korean Implementation Fidelity Checklist of Tier 1 School-Wide Positive Behavior Support (KIFC-T1) for use in the Korean educational system. Tier 1 support, which is universal supports, within a multi-tiered, school-wide positive behavior support (SWPBS) model, aims to provide support to and prevent problem behaviors among all students in a school. The initial KIFC-T1 consisted of 48 items and 11 factors and was developed based on a literature review. Its content was validated by experts. The validated KIFC-T1 was introduced to 185 special school teachers who had experience implementing SWPBS and who used the instrument to assess the degree to which their schools had implemented Tier 1 support. Based on their responses, the construct validity of the KIFC-T1 was examined using factor, item, and internal consistency reliability analyses. The concurrent validity of the tool was examined using the PBS Evaluation Tool, School Climate Questionnaire, School Discipline Practice Scale, and PBS Effectiveness Scale. The analyses revealed that KIFC-T1 had a stable five-factor structure with 35 items, had good reliability (Cronbach's α=.956, each factor's Cronbach's α=.834-.951), and its results were statistically significantly correlated with those of the PBS Evaluation Tool, School Discipline Practice Scale, and the PBS Effectiveness Scale. However the KIFC-T1's results were not statistically significantly correlated with the results of the School Climate Questionnaire. These results suggest that KIFC-T1 is a reliable and valid tool for assessing the fidelity of universal support implementations.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.49 no.10
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• pp.859-870
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• 2021

KARI (Korea Aerospace Research Institute) is developing a design framework for the concept and preliminary design of eVTOL aircrafts. A low fidelity mission analysis tool was developed for the eVTOL aircrafts of Lift-Tilt Concept, which have tilt propellers and lift propellers, using open source SUAVE package. For its development, a review for the propeller performance analysis functionality was made. To find the trim solution at each mission segment automatically, an algorithm is implemented, using a global optimization technique through parallel processings and DOE(design of experiment). Using the tool, the one seated eVTOL OPPAV(optionally piloted personal air vehicle) was modeled and evaluated, which results were compared with the preliminary design data.

• International Journal of Internet, Broadcasting and Communication
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• v.13 no.1
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• pp.116-122
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• 2021

This study evaluated the effect of simulation training on cardiac arrest in hospitals for inactive nurses with 360 VR content, and attempted to prepare basic data for simulation training for inactiv nurses in the future. The design of this study is an experiment study before and after a single group. The study period was from October 13, 2020 to December 17, 2020. The subjects of the study were a total of 21 nurses who participated in the education program for inactive nurses. For simulation training for inactive nurses, Microsoft Powerpoint, hybrid simulation, high-fidelity simulation, and 360 VR content were applied for theories education and practical education. As a result of the study, the satisfaction level of the curriculum for the cardiac arrest situation in the hospital for inactive nurses was 4.78±0.36 points out of 5 points. Understanding of education was 4.71±0.46 points out of 5 points. Usefulness of education was 4.80±0.40 points out of 5 points. Confidence in airway maintenance before and after training, BLS review, manual defibrillator, emergency medication administration, airway maintenance, emergency situation simulation, and debriefing were all significant. According to the results of this study, simulation training of the situation of cardiac arrest in the hospitals for inactive nurses was effective. In future studies, it will be necessary to develope and verify specific teaching and learning methods by applying various cases of cardiac arrest situations in consideration of the type of hospitals.