• Journal of Chest Surgery
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• 제36권2호
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• pp.118-121
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• 2003

25세 여자 환자가 우측 하흉부 및 좌측 상복부의 불쾌감을 주소로 입원하였다. 흉부 X-선 및 흉부 전산화 단층촬영 소견상 우폐 하엽에 위치하며 횡격막과 접하고있는 4$\times$4$\times$4cm 크기의 둥근 종괴가 관찰되고, 우폐하엽과 우폐 중엽에서 전이성 병변들이 관찰되었나. 시험적 개흉술 결과 우측 횡격막에서 기시한 종괴가 우폐 하엽에 직접 침범되어있었으며. 우폐 하엽과 우폐 중엽의 흉막하에 전이성 병변들이 발견되었다. 종괴에 대한 냉동 절편 조직 검사상 육종으로 진단되어 종괴 기시부의 횡격막 및 종괴에 의해 침범된 부위의 우폐 하엽을 일괄 절제하고 우폐 하엽과 우폐 중엽의 전이성 병변들을 쐐기 절제하였다. 최종 조직 검사상 횡격막의 악성 섬유성 조직구종이었고, 보조적 항암 약물 치료를 추가로 시행하였다. 저자들은 횡경막에서의 발생이 극히 드문 악성 섬유성 조직구종 1례를 문헌고찰과 함께 보고하는 바이다.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제14권1_2호
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• pp.117-123
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• 1992

우측 협부의 종창과 압통을 주소로 내원한 59세의 여자 환자에서 방사선 소견상 우측 상악골의 광범위한 골파괴상이 나타났고 조직생검에서 MFH로 진단되었다. 치료는 술전과 술후에 SWOG외 CY-VA-DIC요법을 변형시킨 화학요법과 총 40Gy의 $^{60}Co$ 방사선요법 그리고 우측 상악골전적출술의 삼자병용요법을 시행하였다. 술후 2년이 경과된 현재까지 재발이나 전이 등의 소경은 관찰되지 않고 있으며 환자의 예후에 대하여 주의 깊은 관찰을 계속하고 있다.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제17권3호
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• pp.289-295
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• 1995

성인의 연조직에 발생하여 섬유아세포양세포 및 조직구양세포의 차륜형의 성장형태를 특징으로 하는 MFH는 주로 장년층의 남성에 호발되는 연조직 질환으로 두경부 영역에서의 발생률은 3% 정도이고, 특히 부비강 부위에 발생된 경우의 5년 생존률은 28% 정도이다. 저자들은 악골에 발생한 MFH 2례에서 항암화학요법과 방사선요법 및 광범위한 외과적 절제술을 시행하였다. 철저한 병리조직학적 검사에 의해 오진의 가능성을 줄일 수 있고, 치료시에는 병용요법을 사용함으로써 술후 재발이나 전이를 감소시킬 수 있으리라 생각된다.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제41권5호
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• pp.270-272
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• 2015

Benign fibrous histiocytoma (FH) is a benign tumor composed of fibroblasts and histiocytes in varying proportions. This tumor is usually found in adult extremities but rarely occurs in deep soft tissues of the oral cavity. As it is difficult to diagnose with physical and radiologic exams, deep benign FH can only be diagnosed by histopathology. We report a case of a 36-year-old female patient who came to our department with painless swelling in the right buccal mucosa. This case report reviews the clinical, radiological, and histological aspects of this tumor.

• 대한골관절종양학회지
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• 제5권3호
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• pp.190-193
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• 1999

Benign fibrous histiocytoma is characteristically composed of fibroblastic and histiocytic cells. Most commonly, this tumor occurs in the dermis and superficial subcutis, but it is uncommon in the knee. We experienced a case of deep benign fibrohistiocytoma in a 38-year-old woman who complained of palpable tender mass on the medial aspect of the right knee. MR imaging findings included a well-delineated oval mass with low signal intensity on T1-weighted and high-signal intensity of T2-weighted images, as well as a marked peripheral contrast enhancement. Histopathologically, the lesion contained a mixture of fibroblastic and histiocytic cells that were often arranged in a cartwheel or storiform pattern and accompanied by varying numbers of inflammatory cells, foam cells, and siderophages. After surgical removal of the lesion, no recurrence was observed.

• 대한세포병리학회지
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• 제9권1호
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• pp.99-104
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• 1998

Anaplastic large cell lymphoma(ALCL) is an uncommon type of non-Hodgkin's lymphoma(NHL) populated with anaplastic, often bizarre cells that express CD30 (Ki-1) antigen. The unusual histologic and cytologic features may cause confusion with other neoplasms, such as poorly differentiated carcinoma, melanoma, Hodgkin's disease, or true histiocytic lymphoma. Although the cytologic features of ALCL have been well described, there are few reports about cytologic findings of the sarcomatold variant of ALCL. We experienced a case of fine needle aspiration(FNA) cytologic findings of ALCL which mimicks malignant fibrous histiocytoma. FNA cytology of chest wall mass in a 62-year-old female with a history of peripheral T-cell lymphoma(Lennert lymphoma) revealed a heterogeneous population of single cells and poorly cohesive cells with large, pleomorphic nuclei and spindle cells gathering around vascular structures within an inflammatory background. Additional features of the neoplastic cells were eccentric, multilobated nuclei with occasional 'wreath-like' configuration; abundant cytoplasm with vacuolization; and prominent nucleoli. The cytologic features suggested sarcoma, especially malignant fibrous histiocytoma. The diagnosis was made retrospectively with an aid of immunocytochemical staining.

• 대한두경부종양학회지
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• 제17권2호
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• pp.230-233
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• 2001

Malignant fibrous histiocytoma (MFH) is a sarcoma that occurs principally in soft tissue and typically involved the skeletal muscle and deep fascia. Although it is one of the most common types of soft tissue sarcoma in late adult life, the involvement of the head and neck area is relatively rare. MFH shows variable histologic appearance, and may be classified into several subtypes(storiform-pleomorphic, myxoid, giant cell, inflammatory, angiomatoid) and the storiform-pleomorphic type is the most common type. The authors have recently experienced a case of MFH in the right maxillary sinus, and report it with a brief review of the related literature.

• Tuberculosis and Respiratory Diseases
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• 제76권6호
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• pp.289-291
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• 2014

Malignant fibrous histiocytoma (MFH), a type of sarcoma, is a malignant neoplasm with uncertain origins that arise from both the soft tissues and the bone. The occurrence of MFH on the chest wall is extremely rare. We hereby report a case of a 72-year-old woman who was incidentally detected with MFH after a traffic accident.

• Investigative Magnetic Resonance Imaging
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• 제17권4호
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• pp.316-320
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• 2013

유방의 악성 섬유성 조직구종은 극히 드문 질환으로 이전에 보고된 대부분의 증례들은 임상병리학적 특성에 초점을 맞추어 이 질환의 영상소견에 대한 분석은 제한적이었다. 우리는 좌측 전완부로 부터 전이된 좌측 유방과 좌측 액와부의 악성 섬유성 조직구종 1예를 유방촬영, 유방 초음파 및 유방 자기공명영상 등의 영상의학적 소견에 초점을 맞추어 보고 하고자 한다.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제30권4호
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• pp.399-403
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• 2008

Benign fibrous histiocytoma(BFH) is a mesenchymal cell-originated tumor composed of cells with fibroblastic and histiocytic differentiation. BFH occurs predominantly on sun-exposed skin of extremities. Oral BFH lesions are uncommon. The majority of oral lesions includes the soft tissue but not the jaw bones. The lesion appears as well-defined multilocular radiolucencies associated with bony swelling when it occurs on the jaw. The lesion induces the thinning and expansion of the cortex and shows many thin, indistinct septa in the lesion. Surgical excision is the choice of treatment. The recurrence rate is low and metastasis has not been reported. We report the clinical, radiographic and microscopic findings of a BFH case occurred in the mandible with literature reviews.