• 제목/요약/키워드: Fibrous

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조직학과 효소활성 방법을 이용한 순 타이타늄과 타이타늄 합금의 상대적인 생체적합성 평가 (Relative Evaluation for Biocompatibility of Pure Titanium and Titanium Alloys using Histological and Enzymatic Methods)

  • 염동성;김병일;이유미;이은정;이성태;성치남;서권일;조현욱
    • Toxicological Research
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    • 제23권4호
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    • pp.331-339
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    • 2007
  • Titanium or titanium alloy is a widely used implant material according to its certified biocompatibility, sufficient strength and ready availability. The purpose of this study was to evaluate the relative biocompatibility of titanium and titanium alloy specimens (Ti-29Nb-13Ta, TiNb and Ti-6Al-4V, Ti64) using in vivo and in vitro methods. For in vivo experiment, the specimens were implanted in the abdominal subcutaneous region of female mice for 2 and 4 weeks. The reaction of connective tissue to specimens was evaluated histologically. The specimens were encapsulated by fibrous connective tissue consisting of fibroblast, fibrocyte and other cells including neutrophil, macrophage, giant multinucleated cell and unidentified cells. Some newly formed blood vessels were located in the fibrous capsule surrounding the implant. Cell types and the thickness of fibrous capsules were examined quantitatively. Most of cell types located in the fibrous capsule were fibroblasts and fibrocytes. The average thickness of fibrous capsules for the TiNb specimens was much thinner than that of the titanium alloy, Ti64. The thickness of the fibrous capsule around all titanium specimens decreased at 4 weeks compared to 2 weeks post-implantation. The biocompatibility of titanium and titanium alloy specimens were also investigated in in vitro method using alkaline phosphatase from MG-63 cells. Alkaline phosphatase activity of the TiNb specimen showed higher activity than the titanium alloy, Ti64. In conclusion, the TiNb alloy with thin capsule thickness in vivo and high alkaline phosphatase activity in vitro will be of considerable use in biomedical applications.

폐에 발생한 악성 섬유 조직구종 1례 보 (Malignant Fibrous histiocytoma of the Lung - A case report -)

  • 나석주
    • Journal of Chest Surgery
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    • 제20권3호
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    • pp.598-602
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    • 1987
  • Primary sarcomas of the lung are rare malignant neoplasms which have usually been classified as fibrosarcomas or leiomyosarcomas. Only 10 cases of primary malignant fibrous histiocytoma [MFH] of the lung have previously been reported in the literatures. The histomorphology of the MFH is marked by their extensive cellular variability, nuclear atypia, abnormal mitotic figures and storiform arrangement of the cells. Recently, we experienced a case of MFH, arising in the parenchyme of lung in 66-year-old male patient, and treated with surgical intervention. So we firstly reported it with review of literatures.

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치근단 낭으로 오진한 단낭성 법랑모세포종 (UNICYSTIC AMELOBLASTOMA MISDIAGNOSED AS AN APICAL PERIODONTAL CYST : A CASE REPORT)

  • 윤정훈;정원균
    • Restorative Dentistry and Endodontics
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    • 제26권2호
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    • pp.124-126
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    • 2001
  • A case of an unicystic ameloblastoma of the mandible presenting as an apical periodontal cyst was reported. The lesion showed an unilocular radiolucency with well delineated border. Histologic examination revealed that a fibrous cyst wall with a lining that consists of partially of ameloblastic epithelium. The overlying epithelial cells are loosely cohesive and resemble stellate reticulum. The fibrous cyst wall of the cyst is infiltrated by typical follicular ameloblastoma. but devoid of inflammatory reaction in the cystic wall. Some considerations regarding differential diagnosis. pathogenesis and biologic behaviour of the lesion were discussed.

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구개 편도 지방종 1례 (A Case of Lipoma of Palatine Tonsil)

  • 최홍식;신승호;김한수;서용석
    • 대한기관식도과학회지
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    • 제7권1호
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    • pp.59-61
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    • 2001
  • Lipomas is one of the most common benign neoplasm in the body, but only rarely occurs in the oral cavity We report here a case of a 49-year-old female with a lipoma of palatine tonsil. Microscopical examination revealed a stromal neoplasm composed of mature fat with the presence of a few thin and anastomosing fibrous septa. The surface epithelium was of nonkeratinizing stratified squamous type. There was the dense fibrous connective tissue between mature fat and surface epithelium. The histopathologic findings and literature on tonsillar lipoma is reviewed.

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종격동내 섬유종증;1례 보고 (Mediastinal Fibromatosis - One Case Report -)

  • 김기출;김기봉;김주현
    • Journal of Chest Surgery
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    • 제25권7호
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    • pp.727-731
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    • 1992
  • Fibromatoses, a broad group of fibrous proliferations of similiar microscopic appearance, show intermediate biological behavior between benign fibrous lesion and fibrosarcoma. they are characterized by the infiltrative growth and the tendency toward recurrence, but they never metastasize. The mediastinal fibromatosis has been extremely rarely reported. We experienced a case of anterior mediastinal fibromatosis ingrowing onto the anterior chest wall in 2-year-old female. A radical surgical resection and anterior chest wall reconstruction was performed successfully.

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재발성 고립성 섬유성 종양의 외과적 치험 (Recurrent Solitary Fibrous Tumor of the Mediastinum)

  • 권영무
    • Journal of Chest Surgery
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    • 제34권4호
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    • pp.368-372
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    • 2001
  • 장막내의 고립성 섬유성 종양은 드물며 대부분 장측 또는 벽측 흉막에서 발생하지만 종격동, 심막, 복막, 폐실질 , 안과 그리고 뇌척수막에서도 발생하기도 한다. 이 종양은 다양성으로 인하여 진단하는데 어려움이 있으며, 특히 종격동이나 흉부 외의 장소에서 발생하는 경우에는 더욱 그러하다. 이 종양의 임상적 양상을 예측하기 어려우며 조직학적으로 양성의 소견을 보이면서, 임상적으로는 악성의 양상을 띠기도 한다. 악성의 임상양상을 보이는 경우는 약 13∼23% 정도로 보고되고 있다. 저자는 53세의 여자 환자에서 종격동의 고립성 섬유성 조양을 수술한 후, 4차례 재발한 드문 증례를 수술 치험하였기에, 문헌 고찰과 함께 보고하는 바이다.

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Successful Management of a Recurrent Primary Malignant Fibrous Histiocytoma of the Lung: Report of a Case

  • Jeon, Yun-Ho;Park, Ki-Sung
    • Journal of Chest Surgery
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    • 제45권5호
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    • pp.345-347
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    • 2012
  • We describe herein an extremely rare case of a recurrent primary pulmonary malignant fibrous histiocytoma 3 months after operation that occurred in a 55-year-old man who was treated with chemotherapy and radiotherapy successfully. Until now, 36 months later, the patient has shown no evidence of tumor recurrence. The clinical, radiographic, and pathologic features are reported here together with a brief review of the literature.