• 제목/요약/키워드: Female newborn

검색결과 88건 처리시간 0.253초

단일기관에서 이중 질량 분석법(tandem mass spectrometry technology)을 이용한 선천성 대사이상 검사의 위양성율에 대한 연구 (Investigation of False Positive Rates Newborn Screening using Tandem Mass Spectrometry (TMS) Technology in Single Center)

  • 김현수;신손문;고선영;이연경;박성원
    • 대한유전성대사질환학회지
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    • 제16권1호
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    • pp.18-23
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    • 2016
  • TMS가 확산되고 검사가 많아짐에 따라 위양성 건수도 증가하고 있다. 본 연구에서는 2012년 1월 1일부터 2014년 12월 31일까지 단일 기관에서 출생한 신생아를 대상으로 시행한 TMS의 위양성율을 조사하고 관련된 요인들을 분석하였다. 총 검사 대상자 중 남아는 8,942명(51.7%), 여아는 8,350명(48.3%)이었고, 평균 제태연령은 $38.6{\pm}1.7$주 였다. 평균 출생 체중은 $3,155.6{\pm}502.4g$, 평균 출생 신장은 $49.1{\pm}2.9cm$, 평균 체질량지수는 $13.0{\pm}3.8kg/m^2$ 이었다. 질식 분만은 9,713 (56.2%)건, 제왕절개는 7,579 (43.8%)건이었다. 평균 검사 시행일은 $2.8{\pm}1.1$일이었다. 위양성을 포함하여 TMS에서 양성으로 확인된 224명은 전체 대상자의 1.3%였다. 다중 로지스틱 회귀분석을 통해 분석한 결과 27주 이하의 초미숙아에서 위양성으로 나타날 odds ratio가 6.957 (95% CI: 1.273-38.008), 1,000 g 이하의 극저체중아에서 5.616 (95% CI: 1.134-27.820)로 나타났다. 위양성 대상자들 중에서는 지방산 대사이상 질환(fatty acid oxidation dis-orders)이 104명(47%), 아미노산 이상질환(amino-acidopathy)가 75명(34%), 유기산 이상 질환(organic aciduria)가 43명(19%)이었다. 전국적인 자료를 모아 평가한다면 국내 발생률에 대한 정확한 평가 및 접근이 가능할 것으로 생각한다.

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신생아 중환자실에 입원한 환아 어머니의 스트레스 (A Study on the Perceived Stress of Mothers in Neonatal Intensive Care Unit)

  • 최성희
    • Child Health Nursing Research
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    • 제4권1호
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    • pp.60-75
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    • 1998
  • The parents have much expectation upon the pregnancy and child birth, and in most cases, they expect the healthy parturient child. However, we can be placed on the high-risk conditions which have the physical, social and immature infant, due to the unexpected results, among the new-born. Accordingly, these high-risk newborn and premature infants will be mostly in NICU, which the concentrated medical treatment can be given, upon their conditions. After their birth and during these periods, they will be divided from the parents, and the nurse will accomplish the bringing-up activities which they can take care of the infant, expected by the parents after their birth. The hospitalization of high-risk newborn including these premature infants is the shocking experience to the parents of family, and thus they can feel the fear and uneasiness, and these reactions of parents are troubled in the behavior at the usual days, and cause the disorder and spiritless status, and these results break the supporting ability of parents, and cause the obstruction. Also, the unavoidable division between the parents and the children as like hospitalization of children can make the parents to feel the alienation emotionally, and this causes the results which the pride on the bringing-up ability of baby gets to be lost. These problems can cause the difficulties on the bonding or the parenting in the further days, and can be related to the neglect and abuse of children. Also, it is gradually increased to study and report which the emotional division by the physical division between the mother and the baby obstructs the normal affection course between the parent and the infant. The stress caused by the birth and the hospitalization of high-risk newborn, as like this, is important in the points which it can uncertainly affect the potential energy for the relationship of parent-child who are finally healthy. Accordingly, the significance and purpose of this study are to understand the contents and degree of stress which the parents of high-risk newborn including the immature child can be experienced from the hospitalization of ICU for their new borns, and thus to offer the basic program to the nursing intervention program for these. The subject of this study is the mother of newborn in NICU of 10 General Hospitals located at the 3one of Pusan, Korea from September 1997 to October 1997, and thus makes the subject of 95 person of parents who agreed to take part in the study and it is descriptive study related to the stress of mother having the newborn in NICU. The method is based on the preceding study related to the stress of mother having the experience of child hospitalization and chronic disease child, and then acquires the advice of specialists group as like 5 nursing professors, and then is amended and supplemented. Total number of questions is 43 items and consists of 5 factors as like medical treatment &nursing procedures, disease status & prognosis, role of parents, communication & inter-personal relationships, hospital environment, and is 5 point Likert Scale. The reliability of this study method is very highly shown to be Cronbach α=0.95. The collected data is analysed as Average, Frequency, Standard Deviation, T-test, ANOVA, Pearson Correlation Coefficient, Duncan multifulrange test by use of SPSS /PC (V7.5). The results of this study is summarized as under. 1. Every characteristics of subject is which the party of mother is 28.70age(±7.48) in the average ages, 51% in the high-school graduate, 38.5% in the christianity, total monthly income is 212.55 thousand won(±1.971), 74.5% in the housewife, 72.9% in the parents and children together living and the number of children to be 1.48person(± 0.6) in average, the recognition on the prognosis of baby is 74.0% in 'Don't know', the relationship with the husband after the hospitalization of babyis 37.3% in 'More Intimate', the relationship with the family of husband to be 48% in 'No-change', and the degree which is consulted with the husband about the baby is 55% in 'very frequently' and the visiting number per week is 4.59(±1.63) in average and the accompanying person in the time of visiting is which the number of husband is 56.3% and thus is the highest. The characteristics of baby is which the age is 21.88days(±16.47) after the birth in average, the sex to be 50 person in the female 52.1% and the order of birth to be 54.2% in the first chid, and the weight in the birth to be 2770gm(±610) and the height in the birth to be 46.26cm(±7.62) in aver age. The medical diagnosis is 37.5% in the premature infant, the career of hospitalization is 96.9% in 'None', and the operation plan is 90.6% in 'None' and the execution of operation is 88% in 'None' and the nursing of incubator is 55.2% in 'Yes', and the method of feeding is 50.5% in 'Oral' and the contents of feeding is 46.9% in the 'Milk'. 2. The total stress degree of subject is almost highly shown to be as 3.36(±0.86). If it is compared upon each cause, 'stress on disease status & prognosis' is highest 3.79(±1.28), and it is in the order of 'stress on medical treatment & nursing procedures' 3.70(±0.93), 'stress on hospital environment' 3.14(±0.86), 'stress on role of parents' 3.18(±0.92) and 'stress on communication & inter personal relationship' 2.62(± 0.77) 3. As the results of checking the notworthiness of stress degree upon each variable of subject, the variable showing the noted difference was the birth weight(γ=-0.16, P=0.04), birth height(γ=-0.23, P=0.03), nursing in the incubator(F=8.93, P=0.04), feed method(F=2.94, P=0.04). That is to say, it is shown which the smaller the birth weight is, the higher the stress degree of mother is noteworthily. Also, the smaller the birth height baby is, the higher the stress of mother is. In the incubator, it os shown which the mother whose baby is nursing in the incubator is higher in the stress degree than other mothers. Upon the feeding method of baby, that is to say, TPNis the highest, and it is shown in the order of NPO, Tube feeding, and P.O. feeding. When we review the above-mentioned results, as the status is serious, it is thought which we include the supporting nursing for coping with the stress of parents in the setting-up od nursing plan for the baby in the NICU.

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실험실 사육에 의한 한국산 실고기과(Syngnathidae) 2종, 풀해마(Urocampus nanus)와 실고기(Syngnathus schlegeli)의 초기생활사 비교 (Comparative Early Life History of Two Pipefish, Urocampus nanus and Syngnathus schlegeli (Syngnathidae) in Laboratory Culture from Korea)

  • 이재환;김진구
    • 한국수산과학회지
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    • 제53권1호
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    • pp.83-89
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    • 2020
  • This study provides a detailed morphological description of larvae obtained from Urocampus nanus and Syngnathus schlegeli male brood fish over 20 days of culture in the laboratory. In both species, mating takes place when several males each spread their brood pouch like a wing to attract a female's attention. When the female begins to swim upward, the males follow her and receive her eggs in their brood pouches. Newborn larvae of U. nanus and S. schlegeli had already completed formation of dorsal and caudal fin rays, but not of pectoral fin rays. Pectoral fin rays were completely formed 15 days after release in S. schlegeli and 20 days after release in U. nanus. The ratio of caudal fin length to standard length increased until 8 days and decreased thereafter in S. schlegeli, while in U. nanus this ratio declined continuously after hatching. The larvae of the two species were very similar in external morphology, but well distinguished by the number of dorsal fin rays (15-16 in U. nanus vs. 39-43 in S. schlegeli), the presence of a membrane under the tail (absent in U. nanus vs. present in S. schlegeli), and the presence of melanophores in the dorsal fin (present in U. nanus vs. absent in S. schlegeli). Based on this study, U. nanus appears to be evolutionally more similar to pipefish than to seahorse.

임신부의 건강이 신생아의 체중과 신장에 미치는 영향

  • 김영매
    • 대한간호학회지
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    • 제1권1호
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    • pp.49-58
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    • 1970
  • For the purpose to clarify the effects of the mothers health during pregnancy on the weight and length of the newborn infants, this study was carried out on 500 new born infants delivered at St, Mary's Hospital, Ewha Woman's University Hospital and Red Cross Hospital in Seoul during the eight-month period from March, 1969 to October, 1969. In this study, the relationship between the T weight and length of the new born infants, and in each case, the weight, length, age, duration of labour, duration of pregnancy, weight gain during pregnancy and diets level during pregnancy of the mother were observed. The relationship between the weight and length of the new born infants and the parity n-as also observed. The results obtained in this study were as follows. 1. The weight of new born infants of both sexes was significantly correlated with the parity, the weight of the mother, and the duration of labour of the primipara. The weight of the mother and the duration of pregnancy were significantly correlated with the weight of the male new born infants only, and the weight of the new born infants and the weight gain of the mother during pregnancy were significantly correlated in the female new born infants. 2. In general, the weight of the new born infants of well or excellently nourished mothers were heavier than those of poorly nourished ones. 3. The length of the new born infants was significantly correlated mother the duration of labour in the primipara.

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Newborn English Bulldogs with Multiple Malformation Syndrome and Lethal Characters

  • Jang, Si-Jung;Kim, Minkyung;Lee, Hyeon-Jeong;You, Young-Sung;Lee, Jaehoon;Lee, Sung-Lim
    • 한국동물생명공학회지
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    • 제34권3호
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    • pp.253-258
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    • 2019
  • A female English bulldog was gave birth two neonates by cesarean section on the sixty one days after mating, but both neonates were died soon after birth. The bodies of neonates were diagnosed using radiography, ultrasonography, computed tomography and necropsy immediately after death. Both neonates had caudal regression syndrome, butterfly vertebra, hydrocephalus, umbilical hernia, cleft palate and bow-legged hind-limb. At necropsy, neonates had mild fetal anasarca, cleft lip and the skull was remained non-union. At thoracic cavity, only three ribs and thoracic spines were existed and patent ductus arteriosus was found. At abnormal cavity, the renal ectopia was found with abnormal morphology. In the present case, those English bulldog neonates with multiple congenital malformation syndromes seriously suffered vertebral column anomalies and that may induced by neural tube defects in during embryonic period. To prevent congenital malformation occurring in English bulldog, further in depth studies are needed for the breed specific genetic diversity and for the reason of behind genetic abnormality in these breed.

신생아에서 좌심실유출로 폐쇄를 동반한 심장 횡문근종 치험 1례 (Successful Removal of Left Ventricular Rhabdomyoma : A Rare Cause of Left Ventricular Outflow Obstruction in the Newborn Infant -1 case report)

  • 안병희;문형선
    • Journal of Chest Surgery
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    • 제30권2호
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    • pp.205-208
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    • 1997
  • 심장 횡문근종은 영아나 소아기에서 가장 발생빈도가 높은 원발성 심장종양으로서 결절성 경화증을 빈번히 동반하고, 자연 퇴화가 보고된다 할지라도 좌심실 유출로 폐쇄를 동반한 종양은 아직까지는 예후가 불량하고 수술적 치료가 적응이 된다. 생후 4 일된 신생아가 청색증과 빈 호흡을 주소로 내원하여 생후 4일째에 정중흉골절개를 통한 체외 순환하에 수술을 시행하여 좌심실 유출로를 막고있는 0.7$\times$0.9$\times$0.4cm크기의 종괴를 제거하였다. 수술 후 합병증은 발생하지 않았으며 수술후 14일째에 건강하게 퇴원하였다.

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신생아에서 발생한 태변장폐색증에 동반된 낭성섬유증 1례 (A case of cystic fibrosis presented with meconium ileus in a female neonate)

  • 황인옥;이은실
    • Clinical and Experimental Pediatrics
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    • 제50권12호
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    • pp.1252-1256
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    • 2007
  • 태변장폐색증은 낭성섬유증에서 가장 초기에 나타나는 임상 증상으로 태변이 장관내 축적되어 회장말단의 폐색을 일으키고 복부팽만, 담즙성 구토, 태변 배출 지연이 동반된다. 낭성섬유증은 7번 염색체 장완에 위치한 막전도조절유전자의 돌연변이로 야기되며 한국인에서는 드문 질환이다. 지금까지 대한민국에서 보고된 호흡기 질환에 동반된 낭성섬유증과 달리, 저자들은 태변장폐색증에 동반된 낭성섬유증이 유전자 검사로 진단된 1례를 경험하였기에 보고하는 바이다.

Vitamin D status and childhood health

  • Shin, Youn Ho;Shin, Hye Jung;Lee, Yong-Jae
    • Clinical and Experimental Pediatrics
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    • 제56권10호
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    • pp.417-423
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    • 2013
  • Vitamin D is an essential component of bone and mineral metabolism; its deficiency causes growth retardation and skeletal deformities in children and osteomalacia and osteoporosis in adults. Hypovitaminosis D (vitamin D insufficiency or deficiency) is observed not only in adults but also in infants, children, and adolescents. Previous studies suggest that sufficient serum vitamin D levels should be maintained in order to enhance normal calcification of the growth plate and bone mineralization. Moreover, emerging evidence supports an association between 25-hydroxyvitamin D (25[OH]D) levels and immune function, respiratory diseases, obesity, metabolic syndrome, insulin resistance, infection, allergy, cancers, and cardiovascular diseases in pediatric and adolescent populations. The risk factors for vitamin D insufficiency or deficiency in the pediatric population are season (winter), insufficient time spent outdoors, ethnicity (non-white), older age, more advanced stage of puberty, obesity, low milk consumption, low socioeconomic status, and female gender. It is recommended that all infants, children, and adolescents have a minimum daily intake of 400 IU ($10{\mu}g$) of vitamin D. Since the vitamin D status of the newborn is highly related to maternal vitamin D levels, optimal vitamin D levels in the mother during pregnancy should be maintained. In conclusion, given the important role of vitamin D in childhood health, more time spent in outdoor activity (for sunlight exposure) and vitamin D supplementation may be necessary for optimal health in infants, children, and adolescents.

Canavan Disease 1례 (A Case of Canavan Disease)

  • 손영호;황태규;신종범
    • Clinical and Experimental Pediatrics
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    • 제46권9호
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    • pp.934-938
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    • 2003
  • 저자들은 신생아기에 경련을 보였던 환아에서 소변의 N-acetylaspartic acid의 정량검사를 통해 확진하였으며, 뇌자기공명 소견상 뇌백질의 퇴행성변화를 보였던 Canavan 병 1례를 경험하였기에 문헌 고찰과 함께 보고하는 바이다.

Brittany Spaniel에서 Proteus mirabilis에 의한 유방염 발생: 증례 (Mastitis with Proteus mirabilis in Brittany Spaniel, a case)

  • 이정원;추금숙;곽길한;고원석;송희종
    • 한국동물위생학회지
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    • 제32권3호
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    • pp.215-218
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    • 2009
  • The dog breeding kennel bacterial infection are very significant in perinatal mortality. In many case, Staphylococcus aureus, Streptococcus, and Escherichia coli were infected in intra-uterine or by the genital tract to the puppies, and they are cause of septicemic death of the puppies and clinical mastitis of bitch, leading to septicemic death of newborn puppies. Severe mastitis due to bacterial infection was diagnosed in a 2 year-old female Brittany Spaniel which loss 6 puppies with odor small rice sharp white diarrhea of nine puppies. Bright curd milk and intestinal sample were inoculated on MacConkey agar, blood agar and brain heart infusion agar, and incubated at $37^{\circ}C$ for 24-48 hrs. Gram negative colonies isolated from these sample which were characterized as Glu, Ure, $H_2S$, Orn, Cit, and Cl, and were identified by Microscan Walk-Aways Baxter, American Type Culture Collection, USA) as Proteus mirabils. The isolate was more sensitive to ampicillin, gentamicin, cefoxitin, cefuroxime, and cefazidime. In this results, we confirmed that cause bacteria of septicemic death in puppies was P. mirabilis.