• 동의생리병리학회지
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• 제33권4호
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• pp.239-248
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• 2019

There are no published data on Gyeongokgo (GOK) safety or efficacy despite being commonly use. The Gyeongokgo (GOK) is commonly used in traditional Korean medicine to promote a health qi and blood, but their objective data was not sufficient in clinical field. To investigate the safety and efficacy of GOK with hematologic and serologic testing and the change of the quality of life in healthy individuals. Randomized, subject-assessor-blind, placebo-controlled, single-center pilot study Participants and Interventions 29 healthy volunteer subjects were randomly placed into the GOK group (n = 20) or placebo control group (n = 9) and instructed to take one treatment packet (GOK or placebo) twice daily for 4 weeks. Subjects were assessed using the Fatigue Severity Scale (FSS) and Short Form 36 Health Survey (SF-36) and underwent hematologic and serologic tests and body composition analysis. The FSS total score (p = 0.093) and SF-36 general health index (p = 0.002) were improved following treatment in the GOK group. Post-treatment thyroid-stimulating hormone levels were increased in the GOK group compared with pre-treatment levels (p = 0.0042). C-reactive protein levels decreased (p = 0.0256) in the GOK group compared with that the placebo group. In time-series tests, GOK did not affect post-prandial serum triglycerides, glucose, insulin, or C-peptide levels. Notably, elevations in serum fasting triglycerides at 2- (p = 0.0333) and 4-hours (p = 0.0414) post-prandial were lower than those in the placebo group. GOK reduced fatigue levels and did not significantly affect laboratory test results performed to measure safety, serum glucose, and lipid profiles. Post-meal triglyceride levels were effectively reduced with treatment.

• 동의생리병리학회지
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• 제36권6호
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• pp.242-246
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• 2022

The purpose of this study is to report on the clinical improvement of a patient treated with Korean medicine for Post COVID-19 syndrome. A 52-year-old male patient with headache and chronic fatigue was diagnosed with post-acute COVID-19 syndrome. He had clinical symptoms such as headache, sweating, fatigue, and insomnia and was treated with acupuncture and herbal medicines such as Sasammaekmoondong-tang. To assess the treatment outcomes, the authors used the Fatigue Severity Scale (FSS) and the Numeral Rating Scale (NRS). Following treatment, fatigue improved, with the FSS score dropping from 48 at the first visit to 18 at the final visit, and clinical symptoms such as headache and insomnia disappeared. According to the findings of this study, Korean Medicine could be used in the clinic to treat post-COVID-19 complications.

• 성인간호학회지
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• 제29권2호
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• pp.190-199
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• 2017

Purpose: The purpose of this study was to investigate the differences in sleep, fatigue, and neurocognitive function between shift nurses and non-shift nurses. Methods: A cross-sectional descriptive study design was used. A total of 100 nurses participated in the study. 50 were shift nurses and the remaining 50 were non-shift nurses. The Pittsburgh Sleep Quality Index, Fatigue Severity Scale, and a computerized neurocognitive function test (CNS Vital Signs-VS4) were administered to the subjects to assess verbal and visual memory, processing speed, reaction time, and simple attention. After the last night shift, the shift nurse conducted the study at around 8:00 am and the non-shift nurse participated after work. Results: Compared to non-shift nurses, shift nurses had a significantly lower sleep quality (p=.002) and higher fatigue (p=.001) and achieved significantly lower scores on verbal memory (p=.001), processing speed (p=.003), and reaction time (p=.018). There were significant correlations between sleep quality and processing speed (p=.042), and reaction time (p=.015) of shift nurses who were bad sleepers. Conclusion: This study findings suggest shift work could interfere with cognitive function. Personal and organizational programs should be developed to support their sleep and neurocognitive function.

• 지역사회간호학회지
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• 제13권4호
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• pp.710-718
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• 2002

Purpose: The purpose of this study was to identify the relationship between fatigue, and self-efficacy in patients with lung cancer. Method: The data was collected from January 21th to April 8th 2001. The study subjects were recruited from K hospital in Pusan, Korea. Their fatigue was measured using the 22-item Revised Piper Fatigue Scale developed by Piper et al. (1998) and translated by the investigators, and self-efficacy was measured using the 10-item General Self-efficacy Questionnaire developed by Lee, Schwarzer & Jerusalem. The data were analyzed by SPSS 10.0 program using frequency, percentage, mean and standard deviation, t-test, ANOVA, Post-hoc test (Scheffe's test), and Pearson Correlation Coefficients. Result: 1) The mean fatigue score was $118.48{\pm}33.02$ (range: 22-220). The scores for sub-dimension were $35.40{\pm}10.06$ in behavior/severity, $25.98{\pm}9.06$ in affective score, $27.88{\pm}10.06$ in sensory score, and $29.22{\pm}8.27$ in cognitive/mood. The mean self-efficacy score was $28.80{\pm}5.85$. 2). There were significant differences in the fatigue of patients with lung cancer on income per month (F=4.651, p= .014), 'present pain' (F=2.601, p= .012), 'change of weight' (F=5.911, p= .005), by general characteristics. 3) There were significant differences in the self-efficacy of patients with lung cancer on 'religion' (F=3.732, p= .031), 'employment status' (F=5.525, p= .003), 'past therapy' (F=2.869, p= .034), by general characteristics 4) There was a significant negative correlation between fatigue and self-efficacy (r=- .528, p= .000). Conclusion: Patients with lung cancer experience fatigue. Increased fatigue is associated with decreased self-efficacy. Nurses must provide patients with nursing care for the less occurrence of fatigue and interventions to manage self-efficacy for them.

• 성인간호학회지
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• 제14권3호
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• pp.378-389
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• 2002

Purpose: The purpose of this study was to identify the relationship of fatigue and quality of sleep in patients with cancer. Method: The data was collected from January to February 2001. Study objects were recruited K university hospital in Busan, Korea. Their fatigue was measured using the Revised Piper Fatigue Scale developed by Piper et. al(1998), and quality of sleep was measured using Quality of Sleep Questionare by Oh et. al(1998). Result: 1) The fatigue score was mean $114.80{\pm}34.88$(range: 22-220). The sub dimension that showed behavior/severity score at $33.70{\pm}13.89$, affective score at $24.23{\pm}3.33$, sensory score at $27.74{\pm}12.51$, and cognitive/mood score at $29.11{\pm}3.71$. And sleep quality score was mean $37.32{\pm}8.18$. 2) There was a significant difference in religion(F=4.157, P= .008), present therapy(F=2.536, P= .043), past therapy(F=6.625, P= .000), major caregiver(F=3.133, P= .028), and change of weight(F=7.965, P=.006), according to general characteristics in the fatigue in patients with cancer. 3) There was a significant difference in present pain(t=-2.103, P= .037) and change of weight(F=5.484, P=.005), according to general characteristics in the sleep quality in patients with cancer. 4) There was a significant negative correlation between fatigue and quality of sleep(r=- .340, P= .000). Conclusion: Patients with cancer experience in fatigue. Increase in fatigue are associated with decreases in quality of sleep. Nurses must provide patients with nursing care about the occurrence of fatigue and interventions to deal with sleep disturbance.

• 문화기술의 융합
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• 제6권4호
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• pp.311-316
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• 2020

본 연구는 간호대학생들의 수면의 질을 조사하고, 그에 영향을 미치는 요인을 확인하기 위한 서술적 조사연구이다. 설문도구는 피로증상척도, 한글판 스트레스 자각척도, 한국판 피처버그 수면의 질 평가척도를 사용하였으며, 수면의 질 도구에서 제시한 절단점 점수를 기준으로 비숙면군과 숙면군으로 나누어 분석하였다. 대상자들의 수면의 질은 비숙면군 30.5%, 숙면군 69.5%이며, 피로는 4.39점 vs. 4.27점(t=577, p=.564), 스트레스는 22.2점 vs. 19.0점(t=3.565, p=.000), 수면의 질은 11.2점 vs. 5.7점(t=20.375, p=.000)이었다. 두 군간 수면의 질의 하위 영역 7개는 모두 유의한 차이가 나타나, 비숙면군이 숙면군보다 피로가 높고, 수면의 질이 낮은 것으로 나타났다. 수면의 질에 영향을 미치는 요인으로는 잠자리에 드는 시간과 스트레스로 설명력은 22.1%로 나타났다. 간호대학생들의 적절한 수면을 위한 중재프로그램 계획시 잠자리에 드는 시간과 스트레스 관리를 위한 전략이 필요하다.

• 대한한방내과학회지
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• 제40권2호
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• pp.173-180
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• 2019

Objective: In this case report, we address the case of a 47-year-old man with anemia due to chronic kidney disease. Methods: A patient was treated with Korean medicine including an herbal medication, Shipjeondaebo-tang. We evaluated the improvement of symptoms by biochemical examination of blood, complete blood cell count and total score of Fatigue Severity Scale (FSS). Results: After 15 days of Korean medicine treatment, there was an increase in hemoglobin states, even after intervention ended, for over 30 days with improvement of the patient's fatigue. Conclusions: This study suggested that Shipjeondaebo-tang might be effective in patient's renal anemia and fatigue recovery.

• 동의생리병리학회지
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• 제34권1호
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• pp.37-44
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• 2020

Previous studies have reported an association between poor sleep and various symptoms and diseases, such as fatigue, obesity, depression, and anxiety. The effects of poor sleep may differ by age and sex. In addition, sleep characteristics and their effects may vary according to Sasang constitutional type. The aim of this study was to investigate the associations between sleep quality, fatigue, and quality of life and to assess whether these differ by constitutional type. Participants were individuals aged 40-69 years living in two Korean communities in 2012-2014. Sleep quality, fatigue, and quality of life were measured using the Pittsburgh Sleep Quality Index (PSQI), the Fatigue Severity Scale, and the 12-item Short Form Health Survey, respectively. The effects of total PSQI score and PSQI component scores were analyzed using a generalized additive model. A Korean Sasang constitutional diagnostic questionnaire was used to assess Sasang constitution. Data for 5,793 participants were analyzed. Poor sleep quality was related to greater fatigue, and lower physical and mental quality of life. The PSQI components including subjective sleep quality, sleep latency, sleep disturbances, use of sleep medications, and daytime dysfunction were associated with fatigue and physical and mental quality of life. Sleep quality was significantly lower in So-Eum compared to So-Yang and Tae-Eum. PSQI component scores for fatigue and quality of life differed significantly by Sasang constitution: for Tae-Eum, sleep latency and use of sleep medications; for So-Eum, daytime dysfunction; and for So-Yang, use of sleep medications and daytime dysfunction. The effects of different aspects of sleep quality differ by Sasang constitution. To improve sleep quality, interventions need to be tailored to constitutional type.

• 자동차안전학회지
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• 제11권4호
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• pp.22-27
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• 2019

In this paper, the vibration load and analysis results for automotive battery supporter were performed to provide efficient vibration tolerance performance prediction methods for single-product vibration tolerance testing, and the major influencing factors and considerations for setting up single-unit vibration tolerance tests were reviewed. A common applicable standard load was applied to efficiently predict the performance of single-unit vibrations through the frequency response analysis technique. The results similar to test results can be predicted by checking vulnerable parts of the vehicle components for vibration loads and applying scale factor to standard loads. In addition, it was confirmed that the test conditions with a frequency generating the same durability severity as the endurance test are needed for accurate prediction of the durability of the single-unit vibration tolerance test conditions, and the acceleration and frequency with the conditions that there is no significant nonlinear phenomena in the vibration system are established during the single-unit vibration tolerance test conditions.

• Korean Journal of Acupuncture
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• 제28권3호
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• pp.151-163
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• 2011

Objectives : Our aim is to evaluate feasibility for massive clinical research and to make basic analysis of efficacy and safety of acupuncture treatment for chronic fatigue syndrome and idiopathic chronic fatigue. Methods : This study is a protocol for a pilot randomized controlled trial. It was developed through literature searches and discussions among researchers. Results : Forty participants allocated to acupuncture group and wait-list group. Participants allocated to acupuncture group will be treated three times per week for a total of 12 sessions over four weeks. Eight points (GV20; bilatral GB20, BL11, BL13, BL15, BL18, BL20, BL23) have been selected for the acupuncture group. Participants in the wait-list group will not receive acupuncture treatment during study period and follow-up will be made in the 5th and 9th weeks after random allocation. Then the same acupuncture treatment as that performed to the acupuncture group will be made to the wait-list group. Fatigue Severity Scale, a short form of Stress Response Inventory, Beck Depression Inventory, and Insomnia Severity Index will be used as outcome variables to evaluate the efficacy of acupuncture. Safety will be assessed at every visit. Conclusions : The trial based on this study will be performed. The results of the trial will provide basis for the efficacy and safety of acupuncture treatment for chronic fatigue syndrome and idiopathic chronic fatigue.