• 제목/요약/키워드: Fat bodies

검색결과 64건 처리시간 0.029초

급식회수(給食回數)가 면양(緬羊)의 열량대사(熱量代謝) 및 조직(組織)의 화학적성분(化學的成分)에 미치는 영향 (Effects of Frequency of Meals on Energy Utilization and Body Composition of Sheep Ingesting Diets of Equal Amount)

  • 한인규
    • Applied Biological Chemistry
    • /
    • 제8권
    • /
    • pp.21-28
    • /
    • 1967
  • 등량(等量)의 사료(飼料)로서 급식회수(給食回數)를 달리 했을때 면양(緬羊)의 증체(增體), 영양소(營養素)의 소화율(消化率), 열량이용성(熱量利用性), 체조직(體組織)의 화학성분(化學成分)에 미치는 영향(影響)을 연구(硏究)하기 위하여 32두(頭)의 면양(緬羊)으로 두개(個)의 실험(實驗)을 하였든바 그 성적(成績)은 다음과 같다. (1) 영양소(營養素)의 소화율(消化率) 및 ME가(價)에 있어서 1 일(日) 1회(回) 8급식구(給食區), 1 일(日) 8회급식구(回給食區), 1 일(日) 1회급식(回給食)+7회첨수구(回添水區)사이에 하등(何等)의 차이(差異)가 발견(發見)되지 않았다. (2) 매대사체중당(每代射體重當) 열발생량(熱發生量)은 1 일(日) 8회구(回區)가 1회구(回區)보다 훨씬 적었다. (3) 1 일(日) 8회구(回區)보다 증체량(增體量)이 더 많았다. (4) 1 일(日) 8회구(回區)의 경우 체단백질(體蛋白質), 지방(脂肪), 에너지의 증가(增加)가 1회구(回區)보다 훨씬 왕성하였다. (5) 증체(增體)된 부분(部分)의 체조성(體組成) 변화(變化)를 보면 1회구(回區)의 경우에 훨씬 많은 량(量)의 지방(脂肪), 단백질(蛋白質), 광물질(鑛物質)이 비축되었다. (6) 급식회수(給食回數)가 위에서 본바와 같은 영향을 일으키는 생리적기전(生理的機轉)의 일부(一部)가 설명(說明)되었다.

  • PDF

제2형 당뇨병환자에서 혈중 글루카곤 농도와 심혈관 질환 위험도의 관계 (The relationship between glucagon levels and cardiovascular risk in patients with type 2 diabetes)

  • 정우석;문재철;유소연
    • Journal of Medicine and Life Science
    • /
    • 제17권2호
    • /
    • pp.47-52
    • /
    • 2020
  • Glucagon regulates glucose and fat metabolism as well as being involved in the production of ketone bodies. The new antidiabetic drug, a sodium-glucose co-transporter-2 inhibitor, increases glucagon, and reduces the risk of cardiovascular death and hospitalization due to heart failure. The presence of metabolic syndrome is an important risk factor for cardiovascular diseases(CVD) in type 2 diabetes(T2DM) patients. We, thus, investigated the association between glucagon levels and metabolic syndrome in T2DM patients. This cross-sectional study involved 317 T2DM patients. Fasting and postprandial (30 min after ingestion of a standard mixed meal) glucagon levels were measured. Metabolic syndrome was defined according to the criteria of the International Diabetes Federation. A multiple regression logistic analysis was employed for statistical evaluation. A total of 219 (69%) subjects had metabolic syndrome. The fasting and postprandial glucagon levels did not differ between the group with metabolic syndrome and the group without. Postprandial glucagon levels increased significantly with the increase in the number of metabolic syndrome components, but the fasting levels did not. However, a hierarchical logistic regression analysis revealed that the postprandial glucagon levels did not contribute significantly to metabolic syndrome even after adjusting for other covariates. Fasting and postprandial glucagon levels are not associated with metabolic syndrome in T2DM patients. However, further studies are needed to investigate the relationship between glucagon and cardiovascular risk in patients with T2DM.

Effects of Propylene Glycol on Milk Production, Serum Metabolites and Reproductive Performance during the Transition Period of Dairy Cows

  • Lien, T.F.;Chang, L.B.;Horng, Y.M.;Wu, Chean-Ping
    • Asian-Australasian Journal of Animal Sciences
    • /
    • 제23권3호
    • /
    • pp.372-378
    • /
    • 2010
  • The objective of this study was to investigate the effects of an oral drench of propylene glycol (PG) on milk production, serum metabolites and reproductive performance during the transition period of animals. Twenty-four 2-3 multiparous Holstein cows (average body weight 565 kg, body condition score about 3.6, at the $9^{th}$ month of gestation) were selected, blocked, and then randomly assigned into a PG and a control group. The control and the PG group cows were orally drenched with water or 50 ml sugarcane molasses mixed with 500 ml PG from 7 days pre-partum to 30 days post-partum, respectively. Experimental results indicated that the oral drench PG had no effect on dry matter intake (DMI). The milk yield of the PG group was significantly higher than that of the control group (p<0.05), whereas milk fat content, milk protein and somatic cell counts (SCC) were not significantly different between groups. Concentration of plasma glucose in the PG group was significantly higher than that of the control group (p<0.05). Conversely, the concentrations of non-esterified fatty acids (NEFA), and blood urea nitrogen (BUN) in the PG group were lower than those of the control group (p<0.05). Concentrations of insulin and ketone bodies were not significantly difference between groups. Body condition score (BCS) in the PG group was significantly higher than that of the control group (p<0.05). In reproductive performance there was no difference between groups. The experimental results indicate that supplementation of PG during the transition period of dairy cows can supply energy rapidly, resulting in reduced catabolism of body tissue and increased milk yield.

Growth of Human Colon Cancer Cells in Nude Mice is Delayed by Ketogenic Diet With or Without Omega-3 Fatty Acids and Medium-chain Triglycerides

  • Hao, Guang-Wei;Chen, Yu-Sheng;He, De-Ming;Wang, Hai-Yu;Wu, Guo-Hao;Zhang, Bo
    • Asian Pacific Journal of Cancer Prevention
    • /
    • 제16권5호
    • /
    • pp.2061-2068
    • /
    • 2015
  • Background: Tumors are largely unable to metabolize ketone bodies for energy due to various deficiencies in one or both of the key mitochondrial enzymes, which may provide a rationale for therapeutic strategies that inhibit tumor growth by administration of a ketogenic diet with average protein but low in carbohydrates and high in fat. Materials and Methods: Thirty-six male BALB/C nude mice were injected subcutaneously with tumor cells of the colon cancer cell line HCT116. The animals were then randomly split into three feeding groups and fed either a ketogenic diet rich in omega-3 fatty acids and MCT (MKD group; n=12) or lard only (LKD group; n=12) or a standard diet (SD group; n=12) ad libitum. Experiments were ended upon attainment of the target tumor volume of $600mm^3$ to $700mm^3$. The three diets were compared for tumor growth and survival time (interval between tumor cell injection and attainment of target tumor volume). Results: The tumor growth in the MKD and LKD groups was significantly delayed compared to that in the SD group. Conclusions: Application of an unrestricted ketogenic diet delayed tumor growth in a mouse xenograft model. Further studies are needed to address the mechanism of this diet intervention and the impact on other tumor-relevant parameters such as invasion and metastasis.

Impact of the human body in wireless propagation of medical implants for tumor detection

  • Morocho-Cayamcela, Manuel Eugenio;Kim, Myung-Sik;Lim, Wansu
    • 인터넷정보학회논문지
    • /
    • 제21권2호
    • /
    • pp.19-26
    • /
    • 2020
  • This paper analyses the feasibility of using implantable antennas to detect and monitor tumors. We analyze this setting according to the wireless propagation loss and signal fading produced by human bodies and their environment in an indoor scenario. The study is based on the ITU-R propagation recommendations and prediction models for the planning of indoor radio communication systems and radio local area networks in the frequency range of 300 MHz to 100 GHz. We conduct primary estimations on 915 MHz and 2.4 GHz operating frequencies. The path loss presented in most short-range wireless implant devices does not take into account the human body as a channel itself, which causes additional losses to wireless designs. In this paper, we examine the propagation through the human body, including losses taken from bones, muscles, fat, and clothes, which results in a more accurate characterization and estimation of the channel. The results obtained from our simulation indicates a variation of the return loss of the spiral antenna when a tumor is located near the implant. This knowledge can be applied in medical detection, and monitoring of early tumors, by analyzing the electromagnetic field behavior of the implant. The tumor was modeled under CST Microwave Studio, using Wisconsin Diagnosis Breast Cancer Dataset. Features like the radius, texture, perimeter, area, and smoothness of the tumor are included along with their label data to determine whether the external shape has malignant or benign physiognomies. An explanation of the feasibility of the system deployment and technical recommendations to avoid interference is also described.

한국과 몽골 여대생의 실제체형과 인지체형 및 신체만족도에 관한 비교 (A Comparison of Satisfaction for Actual Body and Perceived Body between Korean and Mongolian Female College Students)

  • 박재경;남윤자;김언주;정선영
    • 한국의류학회지
    • /
    • 제34권9호
    • /
    • pp.1558-1566
    • /
    • 2010
  • This study compares the body sizes of Korean and Mongolian female college students, their perceptions about body size, and body satisfaction based on similar cultural backgrounds. The subjects consisted of 164 Korean students and 171 Mongolian students from March to April, 2008. The age range was 17 to 22 years. We directly measured the body sizes of subjects and examined by questionnaire the degree of body cathexis, perceived body size, and ideal body size. Both Korean and Mongolian college students have similar body measurements but Korean college students have smaller heads, broader and slopped shoulders, and thinner arms and legs. There were insignificant differences in perceived body size for both groups; in particular they perceived that their lower body is fat or thick. However, there were differences in body satisfaction. Both groups had the lowest satisfaction rate for their lower bodies; but in all items, Korean college students had a lower body satisfaction rate than Mongolian college students even though they have thinner arms and legs. Finally, the ideal body style for both groups was a skinny body type, but Korean students preferred a much thinner body type. The body satisfaction rate is greatly affected by the ideal body than the actual body.

Obesity Exacerbates Coxsackievirus Infection via Lipid-Induced Mitochondrial Reactive Oxygen Species Generation

  • Seong-Ryeol Kim;Jae-Hyoung Song;Jae-Hee Ahn;Myeong Seon Jeong;Yoon Mee Yang;Jaewon Cho;Jae-Hyeon Jeong;Younggil Cha;Kil-Nam Kim;Hong Pyo Kim;Sun-Young Chang;Hyun-Jeong Ko
    • IMMUNE NETWORK
    • /
    • 제22권2호
    • /
    • pp.19.1-19.20
    • /
    • 2022
  • Coxsackievirus B3 (CVB3) infection causes acute pancreatitis and myocarditis. However, its pathophysiological mechanism is unclear. Here, we investigated how lipid metabolism is associated with exacerbation of CVB3 pathology using high-fat diet (HFD)-induced obese mice. Mice were intraperitoneally inoculated with 1×106 pfu/mouse of CVB3 after being fed a control or HFD to induce obesity. Mice were treated with mitoquinone (MitoQ) to reduce the level of mitochondrial ROS (mtROS). In obese mice, lipotoxicity of white adipose tissue-induced inflammation caused increased replication of CVB3 and mortality. The coxsackievirus adenovirus receptor increased under obese conditions, facilitating CVB3 replication in vitro. However, lipid-treated cells with receptor-specific inhibitors did not reduce CVB3 replication. In addition, lipid treatment increased mitochondria-derived vesicle formation and the number of multivesicular bodies. Alternatively, we found that inhibition of lipid-induced mtROS decreased viral replication. Notably, HFD-fed mice were more susceptible to CVB3-induced mortality in association with increased levels of CVB3 replication in adipose tissue, which was ameliorated by administration of the mtROS inhibitor, MitoQ. These results suggest that mtROS inhibitors can be used as potential treatments for CVB3 infection.

고콜레스테롤 식이의 급여에 의해 고지혈증이 유도된 흰쥐의 신령버섯 자실체의 항고지혈증 효과 (Anti-hyperlipidemic effect of Agaricus brasiliensis fruiting bodies in rats fed with high cholesterol diet)

  • 진가헌;이태수
    • 한국버섯학회지
    • /
    • 제16권2호
    • /
    • pp.118-124
    • /
    • 2018
  • 신령버섯의 자실체가 고콜레스테롤을 급여한 Sprague Dawley계 암컷 흰쥐의 지질대사와 생리활성에 미치는 영향을 조사하기 위해 생후 5주령의 흰쥐에 표준식이를 급여한 정상 식이군(NC), 정상 식이에 10%의 대두유와 1%의 콜레스테롤을 첨가하여 급여한 고콜레스테롤 식이군(HC), 고콜레스테롤 식이에 신령버섯 자실체 분말을 5% 첨가하여 급여한 군(HC+AB) 등 3개의 실험군으로 나누어 6주간 실험을 수행하였다. 실험동물의 체중증가와 식이효율은 HC에 비해 HC+AB가 유의하게 감소하여 NC와 유사한 수준을 나타냈다. 식이섭취량은 NC에 비해 HC와 HC+AB가 유의하게 낮았다. 혈청의 총콜레스테롤(TC), LDL-콜레스테롤(LDL-C), 중성지방(TG)의 농도는 HC에 비해 NC와 HC+AB가 유의하게 낮았으며 심혈관계 질환의 위험도를 나타내는 동맥경화지수(AI)와 LDL-C/HDL-C의 비율도 HC에 비해 NC와 HC+AB가 유의하게 낮았다. 혈청의 알부민, 크레아티닌, 요산 및 총단백질의 농도도 NC와 HC+AB가 HC에 비해 조금 낮았다. 간기능의 척도를 나타내는 혈청의 GOT와 GPT 효소의 활성은 NC와 HC+AB가 HC에 비해 낮았지만 유의성을 없었고, ALP의 농도는 HC에 비해 NC와 HC+AB가 유의하게 낮아서 신령버섯 자실체 분말의 급여가 흰쥐의 ALP 농도를 낮추는 효과가 있었다. 실험 5-6주 사이에 배출된 변을 채취하여 분석한 총지질과 총콜레스테롤의 양은 HC+AB가 NC와 HC에 비해 유의하게 높아 식이로 섭취한 일부의 지방과 콜레스테롤이 장에서 흡수되지 않고 변으로 배출되는 것으로 나타났다. 따라서 고콜레스테롤 식이에 신령버섯의 자실체 분말을 5% 수준으로 첨가하여 6주간 급여한 흰쥐의 체중, 혈청의 TC, LDL-C 및 TG의 농도와 동맥경화 수치(AI)가 정상 수준을 유지하고 지방간의 발생도 억제되는 효과가 현저히 나타나 고지방과 고콜레스테롤의 섭취에 의해 발생할 수 있는 심혈관계 질환의 예방과 개선에 신령버섯의 자실체가 효과를 나타내는 것으로 사료된다.

Telluric Acid가 흰쥐 간조직의 미세구조에 미치는 영향 (Ultrastructural Changes Induced by Telluric Acid in the Rat Liver)

  • 손석주;정영길;조승묵;백태경;최창도;최월봉
    • Applied Microscopy
    • /
    • 제25권4호
    • /
    • pp.83-103
    • /
    • 1995
  • This experiment was carried out to investigate the effects of telluric acid on the histological and fine structural changes in the rat liver. Fischer 344 rats($150{\sim}200gm$) were used in this study as control and experimental groups. Telluric acid(5 mg/100 gm of body weight) suspensed in olive oil was given intraperitoneally to the animals of the experimental group and only olive oil to those of the control group. At the intervals of 3, 6 and 12 hours, 1, 2, 3, 5, 10, 20, 30 and 60 days after administration, the animals were sacrificed, and livers were obtained from the rats. For light microscopic examination of the liver, sections($5{\mu}m$) were stained with hematoxylineosin(H-E). For electron microscopic examination of the liver, sections were stained with uranyl acetate and lead citrate, finally examined with Zeiss EM 109 electron microscopes. The results obtained were as follows. 1. In the control group, round nucleus. well developed mitochondria, Golgi apparatus, rough endoplasmic reticulum(RER) and numerous glycogen particles were observed in the cytoplasm of the hepatocyte. In the cytoplasmic membranes of the hepatocyte, sinusoidal surface had numerous microvilli and cellular surface is combinated adjacent hepatocyte with desmosomes. The RER cisterns were dilated and zymogen granules were fewer than those of the dark cells. Kupffer cells with irregular nuclear membrane were observed. Fat storing cell and collagenous fiber bundle were observed in the Disse space. 2. Kupffer cell, inflammatory cells in the connective tissue of hepatic triad and lysosome were increased in the 3, 6, and 12 hour experimental group comparing with that of the control group. 3. In the 1 day experimental group, infiltration of inflammatory cells in interlobular connective tissue, dilatation of sinusoidal capillary and increasing of Kupffer cell were observed. Atropic change of hepatocyte and aggregation of glycogen particles in the cytoplasm of hepatocyte were observed. In this group, desmosome near bile canaliculi and collagenous fiber bundle in the Disse space were increased comparing with that of the 12 hours experimental group. In the 2 days experimental group, desmosome, lysosome, peroxisome and collagenous fiber bundle were increased comparing with that of the 1 day experimental group. Furthermore, lamellated bodies were also seen in the cytoplasm of the hepatocyte. 4. In 3 and 5 days experimental groups, transformations of hepatic cell cord and degeneration of the hepatocyte were markedly inclosed comparing with the all experimental groups. And damaged RER and mitochondria. collagenous fiber bundle were also inclosed comparing with that of the 2 days experimental group. Autophagosome and fat storing cells with large lipid droplets were also observed comparing with that of the 2 days experimental group. Tight junction and desmosome between the hepatocytes were separated. These degenerating changes were severe through the all experimental groups. 5. In the 10 and 20 days experimental groups, arrangement of hepatic cell cords and cell organelles of hepatocytes were similar to those of the control group. However, aggregation of glycogen particles, dilatation of sinusoidal capillary and infiltration of inflammatory cells remained. 6. In the 30 days experimental group, the tissue findings were similar to those of the control grout. But lamellated bodies in some hepatocytes and lysosome were remained in the cytoplasms of the Kupffer cells. In the 60 days experimental group, these all changes were recovered as the control group. In conclusion, telluric acid would directly induce the degenerative and necrotic changes on the hepatic tissue. However, these changes were perfectly recoverd in the 60 days experimental group as the control group.

  • PDF

경남 일부 지역 여자 대학생의 상하체 균형 계측치와 운동 습관 (Anthropometric Measurements of the Upper and Lower Body Balance and Exercise Habit among Female College Students in Some Parts of the Gyeongnam)

  • 김영식;윤임실;이원준;남정수;윤중수;윤려민;정한나;고재식;최현주
    • 생명과학회지
    • /
    • 제20권4호
    • /
    • pp.535-542
    • /
    • 2010
  • 경남지역 모 대학교에 재학 중인 여자 대학생 212명을 대상으로 인체 계측과 건강에 관련된 습관에 대하여 설문 조사를 실시하였다. 총대상자의 평균 연령은 20.7 세, 신장은 161.8 cm, 체중은 53.5 kg이었으며, 비만도는 98.4%이었으며 체질량 지수는 $20.6\;kg/m^2$이었고 허리-엉덩이 둘레 비율은 0.80이었다. 이와 같은 신체 계측치는 한국인의 정상 범위에 속하는 것이지만, 조사 대상자의 63.7%가 상체가 하체에 비하여서 불균형적으로 약한 체형인 것으로 나타났다. 이들 대상자를 불균형적으로 상체가 약한 군(UU, n=135)으로 하고 대조군으로써 상 하체가 균형인 군(BU, n=77)의 두 군으로 나누어서 측정 결과치를 비교 분석하였다. 체중, 비만도, 체질량지수, 허리-엉덩이 둘레비가 BU군에 비하여서 UU군이 유의적으로 낮았다. 체단백질, 체지방, 체무기질량도 역시 UU군에서 유의적으로 낮았다. 상완근육 둘레를 측정한 결과, UU군이 BU군에 비하여 유의적으로 낮았다. 운동의 규칙적 수행 여부를 알아본 결과 UU군의 1.5%, BU군에서 7.8%가 '운동을 규칙적으로 하고 있다'고 답하였다. 한편 '운동을 전혀 하고 있지 않다'라고 답한 비율이 UU군과 BU군에서 각각 55.5%, 31.2%로써, 운동을 하지 않는 경우가 UU군에서 1.8배 정도 많았다. 운동을 할 경우에 얼마나 오래하는지에 대한 질문에 UU군의 38.4%와 BU군의 35.8%가 30분 이하로 운동을 한다고 답하여서, 여자 대학생이 운동을 한다 하더라도 운동 시간이 충분하지 않은 것으로 사료된다. 본 연구 조사 결과, 상체가 하체에 비하여서 불균형적으로 약한 여자 대학생이 총 조사 대상자의 63.7%이나 되었으며, 이들의 운동 습관에 문제가 있는 것으로 나타나서 운동을 습관화하여 꾸준히 하고 특히 상체와 팔 근육을 발달시키는 운동을 실천하는 것이 필요하다고 사료된다. 아울러 여자 대학생만을 대상으로 하여 체형의 올바른 인식을 위한 교육의 필요성이 절실하며, 신체 부위의 균형을 고려한 운동 프로그램 개발이 시급하다고 생각한다.