• 제목/요약/키워드: Fast imaging

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Fast temporal detection of intracellular hydrogen peroxide by HyPer

  • Yang, Yu-Mi;Lee, Sung Jun;Shin, Dong Min
    • International Journal of Oral Biology
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    • 제38권4호
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    • pp.169-173
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    • 2013
  • HyPer is the genetically encoded biosensor of intracellular hydrogen peroxide ($H_2O_2$), the most stable of the reactive oxygen species (ROS) generated by living cells. HyPer has a high sensitivity and specificity for detecting intracellular $H_2O_2$ by confocal laser microscopy. However, it was not known whether high speed ratiometric imaging of $H_2O_2$ by HyPer is possible. We thus investigated the sensitivity of HyPer in detecting changes to the intracellular $H_2O_2$ levels in HEK293 and PC12 cells using a microfluorometer imaging system. Increase in the HyPer ratio were clearly evident on stimulations of more than $100{\mu}M$ $H_2O_2$ and fast changes in the HyPer ratio were observed on ratiometric fluorescent images after $H_2O_2$ treatment. These results suggest that HyPer is a potent biosensor of the fast temporal production of intracellular $H_2O_2$.

위상형 직선격자의 자체결상과 가시도 분석 (Self-imaging of a phase line grating and analysis of its visibility)

  • 백승선;이상일;조재흥;김영란
    • 한국광학회지
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    • 제14권6호
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    • pp.606-612
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    • 2003
  • 위상형 직선격자에 가간섭 광원인 레이저 광을 조명하였을 때 이 격자가 렌즈없이 회절에 의하여 결상되는 자체결상 현상(또는 렌즈없는 결상)을 회절이론으로 해석하고 실험적으로 조사하였다. 위상형 격자의 위상분포가 강도분포로 바뀌면서 1:1 로 결상하는 자체결상거리( $Z_{T,a}$)를 진폭형 직선격자의 자체결상시 정의되는 자체결상거리 $z_{T,a}$를 이용하여(4n-3) $z_{T,a}$/4(n=양의 정수)와 같이 새로이 정의하였다. 실험적으로 $z_{T,p}$= $z_{T,a}$/4와 $z_{T,p}$=5 $z_{T,a}$/4에서 위상형 직선격자를 이용하여 자체결상거리에서 자체결상이 되는 것을 확인하였으며, $z_{T,p}$=3 $z_{T,a}$/4위치에서는 이 자체결상된 상의 위상이 반전되는 현상도 동시에 관찰하였다. 이러한 자체결상시 격자의 수에 따라 자체결상된 상의 가시도를 FFT(fast Fourier transform)로 처리하여 측정한 결과, 위상형 직선격자는 15 개 이상의 직선격자들로 구성되어야만 자체결상된 상의 가시도가 최대값 0.10 근처에서 일정하게 유지됨을 알 수 있었다.일정하게 유지됨을 알 수 있었다.

Frequently Asked Questions in the Interpretation of Preoperative and Postoperative Chest CT Scans Related to Lung Cancer Imaging

  • 이경수
    • 대한핵의학회:학술대회논문집
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    • 대한핵의학회 2002년도 춘계학술대회 및 총회
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    • pp.25-27
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    • 2002
  • With the advent of multidetector-row CT, lung cancer imaging is much more promising than before. However, the effectiveness of multidetector-row CT in making an initial diagnosis, staging, and evaluating post-treatment changes of lung cancer still remains to be proved. Fast imaging along with volumetric data set and attendant multi-planar imaging provide much more details on the anatomic changes and pathology associated with lung cancer. However, with images showing anatomic and pathologic changes only, radiologists confront with several questions the answers of which may help evaluate lung cancer more thoroughly. The frequent questions that I have in dally practice of chest CT interpretation are as follows.

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고휘도 디스플레이에서의 인간 시각에 따른 색상 이동 현상과 모델링 (Modeling for Hue Shift Effect of Human Visual System on High Luminance Display)

  • 이태형;이명영;박기현;하영호
    • 대한전자공학회:학술대회논문집
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    • 대한전자공학회 2006년도 하계종합학술대회
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    • pp.307-308
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    • 2006
  • In recent, displays have very good properties at high luminance, fast response, and size. Also They have good quality in terms of color according to the development of the gamut extension and color reproduction. However, despite these merits, there is a characteristic that at a high luminance display, observer perceive the different color from the originally re-producted color due to the change of perceived luminance in human visual system. In this paper, we propose a model that is the hue shift phenomenon between a normal display and a high luminance display, and then an algorithm which compensate the color between two devices, so that observer can perceive the same color.

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하다마드 트랜스폼 이민징 스펙트로미터에 관한 연구 (A Study on Hadamard Transform Imaging Spectromers)

  • 박진배;곽대연;진승희;주진만
    • 대한전기학회논문지:전력기술부문A
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    • 제48권5호
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    • pp.571-579
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    • 1999
  • In this paper, a Hadamard transform imaging spectrometer(HTIS) is proposed by using a grill spectrometer. And we reconfigure the system by using the grill sectrometer which uses a left cyclic S-matrix instead of the conventional right cyclic one. Then, we model the Hadamard transform imaging spectrometer and apply the mask characteristics compensation method, i.e. $ {T}^{-1}$ method, to complete fast algorithm. Also, through computer simulations the superiority of the proposed system in this paper to the conventional Hadamard transform spectrometer(HTS) is proved and the performance of the two systems are compared by introducing average mean square error(AMSE) as the algebraic criterion.

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Halide Perovskites for X-ray Detection: The Future of Diagnostic Imaging

  • Nam Joong Jeon;Jung Min Cho;Jung-Keun Lee
    • 한국의학물리학회지:의학물리
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    • 제33권2호
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    • pp.11-24
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    • 2022
  • X-ray detection has widely been applied in medical diagnostics, security screening, nondestructive testing in the industry, etc. Medical X-ray imaging procedures require digital flat detectors operating with low doses to reduce radiation health risks. Recently, metal halide perovskites (MHPs) have shown great potential in high-performance X-ray detection because of their attractive properties, such as strong X-ray absorption, high mobility-lifetime product, tunable bandgap, low-temperature fabrication, near-unity photoluminescence quantum yields, and fast photoresponse. In this paper, we review and introduce the development status of new perovskite X-ray detectors and imaging, which have emerged as a new promising high-sensitivity X-ray detection technology. We discuss the latest progress and future perspective of MHP-based X-ray detection in medical imaging. Finally, we compare the conventional detection methods with quantum-enhanced detection, pointing out the challenges and perspectives for future research directions toward perovskite-based X-ray applications.

NST/FISS Observations of Ellerman bombs and Surges

  • Yang, Heesu;Chae, Jongchul
    • 천문학회보
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    • 제38권2호
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    • pp.86.2-86.2
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    • 2013
  • Ellerman bombs(EBs) are emission features at the wings of the H alpha spectral line. They are believed to be a kind of a magnetic reconnection feature in the low chromosphere or near photosphere. It was previously reported that surges often occur in association with EBs. However, previous observations were restricted to imaging observation. Using Fast Imaging Solar Spectrograph installed in New Solar Telescope at Big Bear Solar Observatory, California, we observed 5 EBs and associated surges with high-spatial and high-spectral resolutions. In this presentation, we will show the results and discuss the physical properties.

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The Quantitative Diffusion-Tensor Anisotropy of Human Brain Using Fast STEAM DTI

  • 박현정;황문정;김용선;이상권;장용민
    • 대한자기공명의과학회:학술대회논문집
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    • 대한자기공명의과학회 2001년도 제6차 학술대회 초록집
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    • pp.165-165
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    • 2001
  • Purpose: To obtain quantitative diffusion-tensor anisotropy information of human cerebral structu using turbo STEAM diffusion-tensor imaging. Method: Quantitative diffusion anisotropy MR images were obtained in 7 healthy adults using turbo STEAM sequence and a combination of tetrahedral and orthogonal diffusi gradients. Both relative anisotropy(RA) and fractional anisotropy(FA) values were measured various brain regions. The anisotropy index was then compared with the reported valu resulting from EPI-based diffusion tensor imaging.

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