• Parasites, Hosts and Diseases
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• 제59권5호
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• pp.447-455
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• 2021

Vivax malaria incidence in Korea is now decreased and showing a low plateau. Nowadays, vivax malaria in Korea is expected to be successfully eliminated with anti-malaria chemotherapy, primaquine, and vector control. The glucose-6-phosphate dehydrogenase (G6PD) deficiency is associated with potential hemolytic anemia after primaquine administration. This inborn disorder has a pivotal polymorphism with genetic variants and is the most prevalent X-chromosome-linked disorder. The prevalence of G6PD deficiency was previously reported negligible in Korea. As the population of multicultural families pertaining marriage immigrants and their adolescents increases, it is necessary to check G6PD deficiency for them prior to primaquine treatment for vivax malaria. The prevalence of G6PD variants and G6PD deficiency in multicultural families was performed in 7 counties and 2 cities of Jeollanam-do (Province), Gyeonggi-do, and Gangwon-do. A total of 733 blood samples of multicultural family participants were subjected to test the phenotypic and genetic G6PD deficiency status using G6PD enzyme activity quantitation kit and PCR-based G6PD genotyping kit. The G6PD phenotypic deficiency was observed in 7.8% of male adolescent participants and 3.2% of materfamilias population. Based on the PCR-based genotyping, we observed total 35 participants carrying the mutated alleles. It is proposed that primaquine prescription should seriously be considered prior to malaria treatment.

• 한국가정과교육학회지
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• 제3권1호
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• pp.131-146
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• 1991

The purpose of this study is to acquire basic materials to help the students Others of families in their homes through understanding them. This study was based on the questions asked to 100 students without parents in their homes and 100 students in standard homes. Percentage, T-test, counseling sample were used for statistical report. The following are the analysed results of this study. 1. Among the ten events, except for family life and economic problems, there were no distinguished contrasts between the students without parents in their homes and the students in standard homes. 2. The factors influencing stress are mainly plan for future, social environment, school life and learning and students without parents are especially affected by economic problem. 3. Comparing students without parents with one another in stress, the students without parents have economic problem and deficiency of affeetion, the students without father economic problem and their mothers health, the students without mother the difficulty of house affairs and emotional uneasiness of family. The students with step-mother have much misunderstasnding because of the lack of conversation among their family. The students with step-father hardly kconverse with their father and feel uneasy in family life. Based on all can be gailed these results, the following conclusion. 1) The students Other Types of families are stressed much more than the students in standard homes in family life and economic problems. 2) All Students are Stressed by bad environment, the plan of future, scholl and learning, 3) Comparing the Stubents without parents with one another, the students without parents have economics probem and deficiency of affeetion, the students without father economic problem and their mothers health, the students without mother house affairs and emotional uneasiness off family. The students of step-father and step-mother have the misuder standing by the lark of comversation, the deficiency of affection and the uneasiness off family life.

• Journal of Yeungnam Medical Science
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• 제24권2호
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• pp.322-328
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• 2007

Ornithine transcarbamylase (OTC) deficiency is the most common inborn error of urea cycle metabolism; it is inherited in an X-linked manner. The OTC catalyzes the third step of the urea cycle, the conversion of ornithine and carbamyl phosphate to citrulline. Deficiency of OTC leads to the accumulation of ammonia, causing neurological deficits. In most affected hemizygote males, OTC deficiency manifests as hyperammonemic coma that often leads to death in the newborn period, and those who recover from the coma may be neurologically impaired due to the sequelae of the hyperammonemic encephalopathy. In some, late-onset manifestations develop. We report a male neonate with early onset OT deficiency that had apnea and was comatous. On mutation analysis using DNA sequencing after polymerase chain reaction (PCR) amplification of the 10 exons, deletions of 10 bases in codon 285, causing a frame shift was detected in exon 8. The mother and a sister were diagnosed as female carriers. Therefore, genetic counseling and the risk assessment could be provided to the family.

• 대한한의학회지
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• 제44권2호
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• pp.1-9
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• 2023

Objectives: To study symptom differentiation for yang deficiency and blood heat based on 117 psoriasis patients. Methods: Obtained frequency analysis (%), mean (%), and OR, CL(P-value) with prospective pre-post intervention design and multiple regression analysis. Results: There were no statistically significant differences as to sex, BMI, smoking and marital status, but there were statistically significant differences in variables of average age, family history, and alcohol consumption (P<0.05). There were no statistically significant differences in psoriasis symptoms as to initial age of onset, morbidity span, area of the initial onset, and the progression of psoriasis during the last three months of each patient. However, the type of psoriasis showed a statistically significant difference (p=0.011). While there were no statistically significant differences as to common cold, condition of psoriasis after recovering from the cold, skin condition, exercise, and seasonality, irregular perspiration showed significant difference (p<0.00). When confounding factors have been controlled the blood heat patient group as the comparison group, multiple regression analysis showed OR, CI(95%) of 1.06(0.31-3.63) for men, 0.28(0.08-1.06) for aged 30 to 49,0 and 0.18(0.04-0.80) for aged 50 and older. it was 0.06(0.01-0.7) for family history, 1.06(0.29-3.88) for drink alcohol, 19.90(2.53-156.7) for seasonality, and 10.28 (3.19-33.11) for perspiration problems. In these variables, Sex, age, smoking, and alcohol consumption showed no statistically significant results, but family history(p=0.049), seasonality(p=0.005), and irregular perspiration (p=0.017) were statistically significant. Conclusion: Family history, seasonality and irregular perspiration are the determining factors for yang deficiency and blood heat in psoriasis.

• 대한한방내과학회지
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• 제21권5호
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• pp.877-881
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• 2000

Anemia is present in adult if the hematocrit is less than 41%(hemoglobin <13.5g/dL) in males or 37%(hemoglobin <12g/dL) in females. In taking the history, congenital anemia may be suggested by the patient's personal and family history. Poor diet results in folic acid deficiency and may contribute to iron deficiency. Bleeding should always be considered in iron deficiency. Object : The symptoms of this patient are easy fatigability, dizziness, anorexia and paleness of the face. This women is the patient of iron deficiency anemia, cerebral hemorrhage and hypertension. Medication : Gwibitang(歸脾湯) plus(合) Samultang(四物湯) and feroba are dispensed for 30 days. Result : After 30 days, HCT Hb Iron of the laboratory findings are increased and TIBC of the laboratory findings is decreased.

• Journal of Hospice and Palliative Care
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• 제17권1호
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• pp.27-33
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• 2014

목적: 암환자에서는 비타민 D 결핍이 흔하지만, 생애 말기암환자에서 비타민 D 결핍 현황에 대한 자료는 드물다. 저자는 말기암환자를 대상으로 비타민 D 결핍 현황 및 그와 관련된 인자를 파악하고자 하였다. 방법: 일개 호스피스 병동에 입원하였던 말기암환자 133명을 대상으로 후향적 의무기록 관찰을 토대로 진행되었다. 환자의 나이, 성별, 혈중 비타민 D 수치, 암 종류, 신체기능, 약물, 그리고 혈액검사에 대한 자료를 수집하였다. 잠재적인 혼란변수를 보정한 후, 다변량 분석을 통해 혈청 비타민 D 결핍과 연관된 유의한 변수를 확인하였다. 혈청 비타민 D 수치 20 ng/mL 미만을 결핍, 10 ng/mL 미만을 중증 결핍으로 간주하였다. 결과: 대상자의 95%는 혈청 비타민 D 결핍증 상태였다. 남성, 비폐암 환자, $H_2$ 차단제 사용자, 항경련제 미사용자에서 중증 비타민 D 결핍이 더 흔하였다. 혈중 alanine aminotransferase (ALT) 상승 또한 낮은 비타민 D 수치와 관련이 있었다. 다변량 분석에서 중증 비타민 D 결핍이 있을 가능성은, 남성이 여성에 비해 3.82배(95% CI: 1.50~9.72, P=0.005), $H_2$ 차단제를 사용한 환자가 그렇지 않은 환자에 비해 3.94배(95% CI: 1.61~9.65, P=0.003), ALT상승이 있는 환자는 그렇지 않은 환자에 비해 4.52배(95% CI: 1.35~15.19, P=0.015)였다. 결론: 말기암환자에서 비타민 D 결핍 상태는 매우 흔했다. 남성, $H_2$ 차단제의 사용, 그리고 ALT의 상승이 중증 비타민 D 결핍과 관련이 있었다.

• 가족자원경영과 정책
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• 제13권1호
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• pp.41-59
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• 2009

The purpose of this ethnography is to describe and analyze the wild-goose mother's everyday life, her family relationships, and her social networking. Thirteen mothers from New York, California, and Texas, U.S.A., were interviewed with an unstructured questionnaire. Their residency and everyday schedules are arranged around the children's educational conditions. They have experienced difficult relationships with Korean American immigrants, Korean students, other wild-goose mothers, and Americans. They have failed to develop their social capital effectively due to the language barrier and a cultural capital deficiency. As a kind of family strategy, this separation sometimes strengthens the spousal relationship, preventing divorce, but usually weakens the emotional ties and quality of communication between husband and wife. The acculturation gap between the mother and her children may cause the mother to become alienated and exacerbate the generational conflict.

• The Journal of Asian Finance, Economics and Business
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• 제8권5호
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• pp.851-861
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• 2021

This study aims to explore the specific risks in family small-medium enterprises (SMEs) and explain how they manage these risks to sustain and expand. In Indonesia, family business composes around 95 percent of all businesses and contributes about 80 percent to the country's economy. SMEs contribute approximately 57.8 percent to the nation's gross domestic product. Risk management poses challenges to the family business's survival, as family members do not take actions on risk. The assessment of risk is difficult and family businesses lack the ability to determine risk management priorities, including risk management review processes to evaluate risk, thus leading to family business failures. Applying the case study approach, in-depth semi-structured interviews were conducted in seven family SMEs comprising fifteen informants. Additionally, a focus group discussion consisting of three experts is conducted to reaffirm the findings from the interviews, observations, and field notes. The research identified the specific risks and how the family owners strategize to safeguard against these risks such as cash flow deficiency, operations dysfunction, cultural frailty, disharmony, transgenerational entrepreneurship failure, political uncertainty, and unprofessionalism. Comprehending these risks and their strategic decisions elucidated in this research could enable the family owners and key non-family professionals to work hand-in-hand to thrive over the family business risks together. Further avenues of research regarding family business risk management are also suggested in this study.

• 동의신경정신과학회지
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• 제21권2호
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• pp.215-227
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• 2010

Objectives : Jeon-Jeung(癲證) is one of negative symptoms from schizophrenia in Western medecine, which causes flattening of affect, emotional bluntness, and avolition. Compared with positive symptoms of schizophrenia, there is no established treatments that have been proved to be effective for negative symptoms, and since negative symptoms are chronically processed, they finally lead to devastate the mental health. Since Jeon-Jeung(癲證) is usually in set in adolescent period and tends to become chronic through life time, it is important to start getting treatments in early stage by being distinguished from other diseases, such as anxiety disorder. A patient in this case was affective blunting, general weakness, and delusion when sixteen years old. However, he refused to get Western medicine treatment and wanted oriental medicine treatment. Methods : The patient in this case had been suffered from severe stress from his family since he was young and had kept having irregular and unhealthy eating habits. Therefore, he diagnosed stagnant qi transforming into fire(氣鬱化火), heart blood deficiency(心血虛), and spleen-stomach deficiency cold(脾胃虛寒) and since then he had received several treatments including herbal treatment, acupumcture treatment, supportive therapy, and family therapy. These treatments were successful and reduced the level of symptoms. After discharged from the hospital, he had continued receiving outpatient treatment with his family for 8 months and his progress had been still observed after the discharge. Results : The symptoms of patient had been almost reduced and eliminated after he received 29days of admission treatment and the patient got better and better and now lives a normal life 8 months outpatient treatment. Conclusions : This result suggests that our oriental medical treatments and family treatments was effective on schizophrenia.

• 디지털융복합연구
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• 제15권10호
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• pp.357-366
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• 2017

본 연구는 한국 여성의 비타민 D 결핍에 영향을 미치는 요인을 파악하여 한국 여성의 비타민 D 관리를 위한 기초자료를 제시하고자 시도되었다. 본 연구는 제5기 국민건강영양조사 자료를 활용하였으며 만 19세 이상 여성을 대상으로 인구사회학적 특성, 건강관련 특성, 혈중 비타민 D를 파악하였다. 자료 분석은 IBM SPSS 18.0 프로그램을 이용하여 복합표본 설계를 적용하였다. 연구 결과 한국 여성의 비타민 D 결핍률은 81.4%였으며 비타민 D 결핍군과 정상군은 연령, 결혼 여부, 거주 지역, 주거유형, 소득수준, 교육수준에 따라 유의한 차이가 있었다. 비타민 D 결핍 영향요인을 분석한 결과 비타민 D 결핍 위험은 65세 이상 집단보다 19~39세 집단이 2.5배 높았으며 기혼에 비해 미혼인 경우 2배 높았다. 걷기를 실천하지 않는 경우 1.5배, 스트레스를 많이 느끼는 경우 1.5배 비타민 D 결핍 위험이 높았다. 본 연구의 결과에 따라 연령대별 비타민 D 결핍 위험 요인을 밝히기 위한 추후 연구가 필요하며 비타민 D 결핍 예방을 위해 여성의 스트레스 완화와 신체활동 증진이 필요하겠다.