• 제목/요약/키워드: False-negative results

검색결과 302건 처리시간 0.032초

이해관계 선언 (Limitations of 99mTc-DMSA scan in diagnosing acute pyelonephritis in children)

  • 김병기;곽재령;박지민;배기수
    • Clinical and Experimental Pediatrics
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    • 제53권3호
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    • pp.408-413
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    • 2010
  • 목 적 : 소아에서 급성 신우신염 진단시 computed tomography(CT)와 비교하여 $^{99mTc}DMSA$ scintigraphy (DMSA)의 상대적 제한점이 있음을 확인하고자 하였다. 방 법 : 64채널 CT가 도입된 2006년 9월 이후 3년 동안 급성복증이나 발열성 급성병증으로 복부 CT검사를 받은 환아 중 급성 신우신염의 소견을 보였으나 후속으로 시행된 DMSA에서는 이상소견을 발견되지 않은 'DMSA 위음성 환자' 10명을 연구대상으로 선정하여 이들의 임상상과 CT 소견을 분석하였다. CT촬영에는 필립스사의 브릴리언스-64 모델을, DMSA 스캔에는 Siemens사의 Orbiter 75 기종을 사용하였다. 결 과 : 총 10명 중 남자가 8명, 영유아가 8명이었으며 내원당시 평균 1.1일간 발열이 있었고 말초혈액 백혈구 수, 적혈구침강 속도, C-반응단백 등의 급성반응표지가 증가된 상태였다. DMSA 정상 소견을 보였던 10명에서 CT 신장환부 소견은 국소적인 경우가 6례, 미만성인 경우가 4례였다. 대개 일측성이었으며 양측 신장 모두 침범된 경우는 2례였다. DMSA에서 확인되지 않은 CT상 병변 개수는 총 22개 확인되었다. DMSA 비교신기능 측정법은 신손상 정도를 가늠하는데 도움이 되지 않았다. 결 론 : 본 연구를 통하여 DMSA검사는 CT검사상 양성인 급성 신우신염의 신장환부를 밝혀내지 못하는 제한점이 있음이 확인되었다. DMSA 위음성 결과는 주로 질병초기에 영아 환자에서 흔히 발생하는 것으로 보이나, 그 정확한 이유와 발생 비율 등을 밝히기 위해서는 전향적인 추가조사가 필요하다.

3D Vision-based Security Monitoring for Railroad Stations

  • Park, Young-Tae;Lee, Dae-Ho
    • Journal of the Optical Society of Korea
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    • 제14권4호
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    • pp.451-457
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    • 2010
  • Increasing demands on the safety of public train services have led to the development of various types of security monitoring systems. Most of the surveillance systems are focused on the estimation of crowd level in the platform, thereby yielding too many false alarms. In this paper, we present a novel security monitoring system to detect critically dangerous situations such as when a passenger falls from the station platform, or when a passenger walks on the rail tracks. The method is composed of two stages of detecting dangerous situations. Objects falling over to the dangerous zone are detected by motion tracking. 3D depth information retrieved by the stereo vision is used to confirm fallen events. Experimental results show that virtually no error of either false positive or false negative is found while providing highly reliable detection performance. Since stereo matching is performed on a local image only when potentially dangerous situations are found; real-time operation is feasible without using dedicated hardware.

A Novel Technique to Detect Malicious Packet Dropping Attacks in Wireless Sensor Networks

  • Terence, J. Sebastian;Purushothaman, Geethanjali
    • Journal of Information Processing Systems
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    • 제15권1호
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    • pp.203-216
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    • 2019
  • The nature of wireless transmission has made wireless sensor networks defenseless against various attacks. This paper presents warning message counter method (WMC) to detect blackhole attack, grayhole attack and sinkhole attack in wireless sensor networks. The objective of these attackers are, to draw the nearby network traffic by false routing information and disrupt the network operation through dropping all the received packets (blackhole attack), selectively dropping the received packets (grayhole and sinkhole attack) and modifying the content of the packet (sinkhole attack). We have also attempted light weighted symmetric key cryptography to find data modification by the sinkhole node. Simulation results shows that, WMC detects sinkhole attack, blackhole attack and grayhole attack with less false positive 8% and less false negative 6%.

Application of artificial neural network to differential diagnosis of lung lesion: Preliminary results

  • Lee, Hae-Jun;Lee, Yu-Kyung;Hwang, Kyung-Hoon
    • 한국정보처리학회:학술대회논문집
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    • 한국정보처리학회 2011년도 춘계학술발표대회
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    • pp.1614-1615
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    • 2011
  • It is difficult to differentially diagnose between lung cancer and benign inflammatory lung lesion due to high false positive rate on F-18 FDG-PET. We investigated whether application of artificial neural network to this diagnosis may be helpful. We reviewed the medical records and F-18 FDG PET images of 12 patients, selecting clinical and PET variables such as SUV. For selected variables and confirm, multilayer neural perceptron was applied in crossvalidation method and compared to visual interpretation. Neural network correctly classified the lung lesions in 83%, and reduced greately the false positive rate. However, false negative rate was not influenced. Application of neural network to the differential diagnosis between lung cancer and benigh inflammatory lesion may be helpful. Further studies with more patients are warranted.

An Automatic Portscan Detection System with Adaptive Threshold Setting

  • Kim, Sang-Kon;Lee, Seung-Ho;Seo, Seung-Woo
    • Journal of Communications and Networks
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    • 제12권1호
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    • pp.74-85
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    • 2010
  • For the purpose of compromising hosts, attackers including infected hosts initially perform a portscan using IP addresses in order to find vulnerable hosts. Considerable research related to portscan detection has been done and many algorithms have been proposed and implemented in the network intrusion detection system (NIDS). In order to distinguish portscanners from remote hosts, most portscan detection algorithms use a fixed threshold that is manually managed by the network manager. Because the threshold is a constant, even though the network environment or the characteristics of traffic can change, many false positives and false negatives are generated by NIDS. This reduces the efficiency of NIDS and imposes a high processing burden on a network management system (NMS). In this paper, in order to address this problem, we propose an automatic portscan detection system using an fast increase slow decrease (FISD) scheme, that will automatically and adaptively set the threshold based on statistical data for traffic during prior time periods. In particular, we focus on reducing false positives rather than false negatives, while the threshold is adaptively set within a range between minimum and maximum values. We also propose a new portscan detection algorithm, rate of increase in the number of failed connection request (RINF), which is much more suitable for our system and shows better performance than other existing algorithms. In terms of the implementation, we compare our scheme with other two simple threshold estimation methods for an adaptive threshold setting scheme. Also, we compare our detection algorithm with other three existing approaches for portscan detection using a real traffic trace. In summary, we show that FISD results in less false positives than other schemes and RINF can fast and accurately detect portscanners. We also show that the proposed system, including our scheme and algorithm, provides good performance in terms of the rate of false positives.

Comparison of RPR Card and Mediace RPR test by KFDA Guideline

  • Lee, Hae Soon
    • 대한임상검사과학회지
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    • 제44권3호
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    • pp.124-127
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    • 2012
  • Syphilis is an infectious and sexually transmitted chronic disease caused by Treponema pallidum. On the basis of clinical findings, the disease has been divided into a series of overlapping stages, which are used to help guide treatment and follow-up. Persons who have syphilis might seek treatment for signs or symptoms of primary infection, secondary infection and tertiary infection. Latent infections are detected by serologic testing. A presumptive diagnosis of syphilis is possible with the use of two types of serologic tests: nontreponemal tests and treponemal tests assay. The use of only one type of serologic test is insufficient for diagnosis, because each type of test has limitations, including the possibility of false-positive test results in persons without syphilis. KFDA published Koreans guideline of Sexually transmitted infections in 2011. Two hundred samples were tested by RPR card test and Mediace RPR test with simultaneously. The agreement between RPR card test and Mediace RPR test was 95%, the discrepant samples was 5%. The characteristics of 10 discrepant samples was RPR card Positive and Mediace RPR negative nine samples, RPR card negative and Mediace RPR positive one sample. The nine samples were confirmed as FTA-ABS by KFDA guideline of syphilis test algorism, all IgM test was Negative, all IgG test was reactive. So, these cases were past or latent syphilis. The one sample was false-positive reaction.

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젖염소 분방유즙에서 체세포에 대한 연구 (A Study on the Somatic Cells in Half Milk Samples of Dairy Goats)

  • 김혜라;이정치;정지영;이윤경;신성식;이채용
    • 한국임상수의학회지
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    • 제24권2호
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    • pp.177-181
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    • 2007
  • In the present study, a total of 547 half milk samples were collected from 274 dairy goats to perform somatic cell counts (SCC) and California mastitis test (CMT). Milk smear was stained with Pyronin Y-Methyl Green stain were classified into either epithelial or blood cells, etc. Of the 547 halves the percentage of CMT negative milk samples were 86%. Among these, 58.2% were CMT negative with SCC<500,000/ml, while 27.8% were CMT negative with SCC>500,000 ml. As expected, CMT score increased with the increase of SCC. The number of epithelial cells decreased with the increasing number of somatic cells, while the opposite was observed with the number of blood cells. These results indicate that the critical point in milk quality & CMT should be considered on the false (pseudo-SC) SCC in dairy goat.

음의 유사도 비율 누적 방법을 이용한 발화검증 연구 (A Study on Utterance Verification Using Accumulation of Negative Log-likelihood Ratio)

  • 한명희;이호준;김순협
    • 한국음향학회지
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    • 제22권3호
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    • pp.194-201
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    • 2003
  • 음성인식에서 신뢰도 측정이란 인식된 결과에 대한 신뢰 여부를 결정하는 것이다. 신뢰도는 프레임을 음소 및 단어 수준으로 통합하여 측정된다. 단어 인식의 경우, 신뢰도를 이용하여 인식 결과와 미등록 어휘를 검증한다. 따라서 이러한 후처리를 통해 이를 인식 결과로 승인하지 않음으로써 성능을 높일 수 있다. 본 논문에서는 기존의 신뢰도 측정 방법인 로그 유사도 비를 수정하여 신뢰도를 측정하였다. 제안된 방법은 프레임 수준에서 음소 수준으로 신뢰도를 통합할 때 로그 유사도 비가 음수인 것만을 누적하는 것이다. 단어 인식기의 인식 결과에 대한 검증 성능을 기존의 방법과 비교한 결과, CAR (Correct Acceptance Ratio)이 90%인 지점에서 FAR (False Acceptance Ratio)을 미등록 어휘에 대해서는 약 3.49%, 오인식에 대해서는 15.25% 감소시킬 수 있었다

Sentinel Node Biopsy Examination for Breast Cancer in a Routine Laboratory Practice: Results of a Pilot Study

  • Khoo, Joon-Joon;Ng, Chen-Siew;Sabaratnam, Subathra;Arulanantham, Sarojah
    • Asian Pacific Journal of Cancer Prevention
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    • 제17권3호
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    • pp.1149-1155
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    • 2016
  • Background: Examination of sentinel lymph node (SLN) biopsies provides accurate nodal staging for breast cancer and plays a key role in patient management. Procurement of SLNs and the methods used to process specimens are equally important. Increasing the level of detail in histopathological examination of SLNs increases detection of metastatic tumours but will also increase the burden of busy laboratories and thus may not be carried out routinely. Recommendation of a reasonable standard in SLN examination is required to ensure high sensitivity of results while maintaining a manageable practice workload. Materials and Methods: Twenty-four patients with clinically node-negative breast cancer were recruited. Combined radiotracer and blue dye methods were used for identification of SLNs. The nodes were thinly sliced and embedded. Serial sectioning and immunohistochemical (IHC) staining against AE1/AE3 were performed if initial H&E sections of the blocks were negative. Results: SLNs were successfully identified in all patients. Ten cases had nodal metastases with 7 detected in SLNs and 3 detected only in axillary nodes (false negative rate, FNR=30%). Some 5 out of 7 metastatic lesions in the SLNs (71.4%) were detected in initial sections of the thinly sliced tissue. Serial sectioning detected the remaining two cases with either micrometastases or isolated tumour cells (ITC). Conclusions: Thin slicing of tissue to 3-5mm thickness and serial sectioning improved the detection of micro and macro-metastases but the additional burden of serial sectioning gave low yield of micrometastases or ITC and may not be cost effective. IHC validation did not further increase sensitivity of detection. Therefore its use should only be limited to confirmation of suspicious lesions. False negative cases where SLNs were not involved could be due to skipped metastases to non-sentinel nodes or poor technique during procurement, resulting in missed detection of actual SLNs.

자궁경부 세포진검사 및 자궁경부 확대촬영술의 비교연구 (A Comparative Study of Cytology & Cervicography for Cervical Cancer Screening)

  • 하중규;윤달식;이준기;최창근;우양례;이진수;이윤희;박재영;이영임
    • 한국건강관리협회지
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    • 제2권1호
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    • pp.27-37
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    • 2004
  • Background 'For many years, the Papanicolaou smear has been used to detect pre-malignant and malignant disease of the cervix. Although cervical cytology screening programmes have result in the reduction of cervical cancer incidence and mortality, Pap smear have been subjected to intense scrutiny and criticism in recent years. So cervicography is introduced. Cervicography is an adjunct method of cervical cancer screening intended to complement Papanicolaou smear. Cervicography involve obtaining and evaluating a photographic image of the cervix. The purpose of this investigation was to evaluate the efficacy of Papanicolaou smear and cervicography in cervical cancer screening. Materials & Methods : This study population was of 74 women, who visited department of obstetrics & Gynecology, Korea association of Health Promotion Chung-nam branch from January, 20O2 to October, 2003. All patients were taken Pap smear before cervicography, and then two cervicography was obtained with applying5% acetic acid. Those women in whom abnormalities were detected by either test subsequently obtained histologic specimen. Results : 1. The sensitivity and the specificity of Papanicolaou smear was 92.1% and 72.7%respectively.2. The sensitivity and the specificity of cervicography was 88.9% and 54.5% respectively. The false negative rate, and false positive rate of Papanicolaou smear were 7.9%, 27.2% respectively. The false negative rate, and false positive rate of cervicography were 11.1%,45.5% respectively. Conclusions . Papanicolaou smear is a useful method and an important tool for detecting cervical cancer. However when Papanicolaou smear and Cervicograpy is used together, the sensitivity is higher than for Papanicolaou smear used alone.

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