• 한국음향학회지
• /
• 제41권4호
• /
• pp.468-479
• /
• 2022

수중에서 능동소나를 이용하여 표적을 탐지하기 위하여, 송신음이 표적에 반사된 반향을 수신함으로써 표적의 위치를 감지한다. 이때 산란체로부터의 잔향이 발생하며, 이는 표적 반향의 탐지를 방해하게 된다. 효과적인 표적 탐지를 위해 자기회귀 모델기반의 백색화 기법이나 주성분역산 등의 잔향 제거 기법이 연구된 바 있으며, 최근에는 비음수 행렬 분해 기반의 기법이 고안되었다. 비음수 행렬 분해 기반의 잔향 제거 기법은 기존의 기법에 비해 향상된 성능을 보여주지만, 송수신기의 위치 및 거리에 의한 감쇠 등이 고려되지 않았다. 본 논문에서는, 양상태 소나에서 지속파 송신 파형을 사용하는 경우에 대하여 수신기의 방향성과 그에 관련된 도플러, 그리고 거리에 대한 감쇠 등의 전처리를 통해 성능을 개선하였다. 본 연구에서 고안된 시스템의 성능을 확인하기 위하여 잔향 모델을 이용한 시뮬레이션을 수행하였다, 시뮬레이션 결과 1 %의 낮은 오탐지율에서 기존의 비음수 행렬 분해 기법 대비 10 % ~ 40 %의 탐지율 성능 향상이 있음을 확인하였다.

• Journal of Gastric Cancer
• /
• 제11권3호
• /
• pp.155-161
• /
• 2011

Purpose: To determine the diagnostic utility of a frozen section biopsy in patients undergoing endoscopic submucosal dissection (ESD) for early gastric neoplasms with obscure margins even with chromoendoscopy using acetic acid and indigo carmine (AI chromoendoscopy). Materials and Methods: The lateral spread of early gastric neoplasms was unclear even following AI chromoendoscopy in 38 patients who underwent ESD between June 2007 and May 2011. Frozen section biopsies were obtained by agreement of the degree of lateral spread between two endoscopists. Thus, frozen section biopsies were obtained from 23 patients (FBx group) and not in the other 15 patients (AI group). Results: No significant differences were observed for size, histology, invasive depth, and location of lesions between the AI and FBx groups. No false positive or false negative results were observed in the frozen section diagnoses. Adenocarcinoma was revealed in three patients and tubular adenoma in one, thereby changing the delineation of lesion extent and achieving free lateral margins. The rates of free lateral resection margins and curative resection were significantly higher in the FBx group than those in the AI group. Conclusions: Frozen section biopsy can help endoscopists perform more safe and accurate ESD in patients with early gastric neoplasm.

• Environmental Engineering Research
• /
• 제11권5호
• /
• pp.277-284
• /
• 2006

The genetic toxicity of environmental pollutants, namely, nonylphenol (NP), bisphenol A (BPA) and chloropyriphos (CP) was investigated in aquatic sentinel species, freshwater crustacean, Daphnia magna, and larva of aquatic midge, Chironomus tentans, using Comet assay. Physiological effect of such pollutants was also investigated by studying the specimens' rates of reproduction, growth and survival. Acute toxicity results showed that, as expected, Daphnia was more sensitive than Chironomus to chemical exposure. The order of acute toxicity was CP > NP > BPA in D. magna and NP > CP > BPA in C. tentans. BPA may exert a genotoxic effect on D. magna and C. tentans, given that DNA strand breaks increased in both species exposed to this compound, whereas NP- and CP-induced DNA damage occurred only in C. tentans. In vivo genotoxic data obtained in aquatic sentinel species could provide valuable information for freshwater quality monitoring. The experiments with NP-exposed D. magna showed that the pollutant has long-term effects on reproduction, whereas no short-term effect on DNA integrity was found, being an example of a false-negative result from the biomarkers perspective. This result could be interpreted that other mechanism than genetic alteration might be involved in NP-induced reproduction failure in D. magna. False-positive results from the genotoxic biomarker obtained in BPA-exposed D. magna and in NP-exposed C. tentans make it difficult to use DNA integrity as an early warning biomarker. However, as the mere presence of genotoxic compounds, which are potentially carcinogenic, is of high concern to human and ecosystem health, it could also be important to rapidly and effectively detect genotoxic compounds in the aquatic system in ways that do not necessarily accompany a higher level of alteration. Considering the potential of D. magna and C. tentans as bioindicator species, and the importance of genotoxic biomarkers in ecotoxicity monitoring, DNA damage in these species could provide useful information for environmental risk assessment.

• Asian Pacific Journal of Cancer Prevention
• /
• 제14권2호
• /
• pp.1027-1030
• /
• 2013

Background: Peritoneal washing cytology (PWC) that shows the microscopic intra-peritoneal spread of gynaecologic cancers is not used in staging but is known as prognostic factor and effective in planning the intensity of the therapy. False negative or false positive results clearly affect the ability to make the best decision for therapy. In this study we assessed levels of tumour markers, carcinoembryonic antigen (CEA), cancer antigen 125 (CA-125) and carbohydrate antigen (CA19-9), in peritoneal washing fluid to establish any possible contribution to the peritoneal washing cytology in patients operated for gynaecologic cancer. Materials and Methods: Preoperative tumour markers were studied in serum of blood samples obtained from the patients for preoperative evaluation of a gynaecologic operation. In the same group peritoneal tumour markers were studied in the washing fluid obtained for intraoperative cytological evaluation. Results: This study included a total of 94 patients, 62 with malignant and 32 with benign histopathology. The sensitivity of the cytological examination was found to be 21% with a specificity of 100%. When evaluated with CEA the sensitivity of the cytological examination has increased to 37%. Conclusions: In addition to examination of PWC, the level of CEA, a tumour marker, in peritoneal washing fluid can make a diagnostic contribution. Determining the level of CEA in peritoneal washing fluid will be useful in the management of gynaecologic cancers.

• 대한두경부종양학회지
• /
• 제10권2호
• /
• pp.91-101
• /
• 1994

Nodular thyroid disease is a common clinical problem. The problem in clinical practice is to distinguish malignant or potentially malignant tumor from harmless nodules. The cases of thyroid nodule surgically managed at Department of General Surgery, Soon Chun Hyang Univ. Hospital during the period Jan. 1985 to July. 1992 were reviewed retrospectively. To assess method of distinguishing malignant from benign lesions of the thyroid gland, we reviewed 162 patients with thyroid nodule. There were 61(37.7%) malignant nodules and 101(62.3%) benign nodules. According to the review, distinguishing the benign from the malignant nodule with history, physical examination, clinical manifestation, and duration of illness was not suggested sufficiently. In ultrasonogram of 73 cases, 57.5% of nodules were solid, 20.6% were cystic, 21.9% were mixed solid and cystic. Of these, 28.5% of the operated solid lesions, 12.5% of the mixed lesions, and only 6.7% of the cystic lesions were malignant. Thyroid scanning of 82 cases revealed cold nodules in 60 patients(73.2%), of which 26 cases were malignant(36.6%) 137 patients underwent fine needle aspiration cytology(FNAC), and these results were as follow: sensitiviey was 70.6%, specificity was 93.0%, false-positive rate was 14.3%, and false-negative rate was 15.8%. 41 patients underwent frozen biopsy, and the results as follow: sensitivity was 80.0%, specificity was 89.7%. Neither scintigraphy nor ultrasonogram has sufficient specificity to distinguish benign from malignant nodule. But FNAC and frozen biopsy have sufficient accuracy to differentiate benign from malignant nodule. In the benign nodules, the most common type of operation was total lobectomy (60.4%). Of the malignant nodules, total thyroidectomy with or without modified radical neck dissection was performed in 30 cases(49.2%). We conclude that the single technique used to determine the differential diagnosis of a thyroid nodule are unrealiable. It is therefore essential to combine all avaiable clinical and laboratory information.

• Journal of Ecology and Environment
• /
• 제41권12호
• /
• pp.345-350
• /
• 2017

Background: Ecological research often requires monitoring of a specific individual over an extended period of time. To enable non-invasive re-identification, consistent external marking is required. Treefrogs possess lateral lines for crypticity. While these patterns decrease predator detection, they also are individual specific patterns. In this study, we tested the use of lateral lines in captive and wild populations of Dryophytes japonicus as natural markers for individual identification. For the purpose of the study, the results of visual and software assisted identifications were compared. Results: In normalized laboratory conditions, a visual individual identification method resulted in a 0.00 rate of false-negative identification (RFNI) and a 0.0068 rate of false-positive identification (RFPI), whereas Wild-ID resulted in RFNI = 0.25 and RFNI = 0.00. In the wild, female and male data sets were tested. For both data sets, visual identification resulted in RFNI and RFPI of 0.00, whereas the RFNI was 1.0 and RFPI was 0.00 with Wild-ID. Wild-ID did not perform as well as visual identification methods and had low scores for matching photographs. The matching scores were significantly correlated with the continuity of the type of camera used in the field. Conclusions: We provide clear methodological guidelines for photographic identification of D. japonicus using their lateral lines. We also recommend the use of Wild-ID as a supplemental tool rather the principal identification method when analyzing large datasets.

• 문화기술의 융합
• /
• 제7권3호
• /
• pp.163-171
• /
• 2021

이 연구는 코로나19가 야기한 인포데믹 상황에서 유튜브상에서 확산된 코로나19 백신 관련 영상의 주요 특성과 이용자 반응의 차이를 알아보고자 하였다. 코로나19 백신 관련 영상 579개에 대한 내용분석 결과, 허위정보는 모두 개인 채널이 저자인 것으로 나타났으며, 기관 및 단체, 언론사, 정부 채널에서는 사실 중심 보도와 더불어 허위정보에 대한 보도도 한 축을 이룬 것으로 나타났다. 진보 성향의 채널은 백신 접종을 찬성하는 긍정적 정서의 비율이 높았고, 보수 성향의 채널은 백신 접종에 반대하는 부정적 정서의 비율이 높았다. 백신 접종이 시작된 이후에 정부 채널의 영상이 증가했고, 긍정적 정서의 영상이 증가한 것으로 나타났다. 좋아요 수에 영향을 미치는 영상의 특성 요인을 회귀분석을 통해 알아본 결과, 개인 전문가 영상, 진보 성향 채널의 영상이 좋아요를 더 많이 받은 것으로 나타났다. 연구 결과를 종합하여 소셜미디어를 활용한 코로나19 백신 관련 정부 정책 홍보 방안에 대해 제시하였다.

• 한국재난정보학회 논문집
• /
• 제18권2호
• /
• pp.364-373
• /
• 2022

연구목적: 본 논문은 지하공동구의 초기 화재 감지를 위해 CCTV를 활용한 AI 연기 객체 감지 모델을 개발하는데 목적이 있다. 연구방법:비정형성이 높은 연기 객체의 감지 성능을 제고하기 위해 화재 감지에 특화된 딥러닝 객체 감지 모델을 지하공동구 연기 감지에 특화되도록 학습시켰고, 학습데이터셋의 정제 및 학습 중 Gradient explosion 완화 등 감지 성능 개선을 위한 방법들을 적용해 모델 결과를 비교하였다. 연구결과: 결과는 제안된 방법을 통해 모델 성능을 향상시켰고 mAP 등의 지표를 평가를 통해 개발 모델이 우수한 성능을 보유하고 있음을 보여준다. 최종 모델은 지하공동구 환경의 연기에 대해 미탐이 낮은 반면 오탐이 다수 발견되는 성능을 보였다. 결론: 본 논문의 모델은 지하공동구 관리시스템과 연계를 통해 보완함으로써 지하공동구의 연기 객체 감지에 활용할 수 있을 것으로 판단된다.

• 대한두경부종양학회지
• /
• 제6권2호
• /
• pp.114-118
• /
• 1990

A clinical study of 37 cases with thyroid nodules, which were treated by surgical excision and confirmed pathologically at the Department of Surgery, Chonnam National University Medical School, from Dec. 1988 to Feb. 1990, was conducted and following results were obtained in ultrasonographic evaluation of thyroid nodules. 1) The thyroid adenoma were showed well-defined margin, homogenous internal echo and surrounding Halo, but thyroid cancer were showed ill-defined margin, inhomogenous internal echo and no surrounding Halo. 2) The sensitivity of high resoution ultrasonography compared with pathologic diagnosis to thyroid cancer was 87.5%, specificity 94.1%, accuracy 88%, false positive 5.88%, and negative 12.5%.

• 전기학회논문지
• /
• 제58권1호
• /
• pp.210-215
• /
• 2009

In this study event-related optical signals were extracted from the prefrontal cortexes using functional near infrared spectroscopy while subjects were carrying out 2-back working memory tasks. Four events such as start, yes, no, and error were considered based on the onsets of the stimulus, positive true responses, positive false responses, and negative responses in the 2-back working memory task, respectively. The optical signals recorded were analyzed by peri-event histograms and power spectrum distributions. The results showed specific characteristics of the event-related optical neuronal signals and an opened possibility of an application to control a non-invasive brain-computer interface system or an object of a virtual reality.