• Computers and Concrete
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• v.23 no.1
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• pp.61-68
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• 2019

This paper presents a computational rational model to predict the ultimate and optimized load capacity of reinforced concrete (RC) beams strengthened by a combination of longitudinal and transverse fiber reinforced polymer (FRP) composite plates/sheets (flexure and shear strengthening system). Several experimental and analytical studies on the confinement effect and failure mechanisms of fiber reinforced polymer (FRP) wrapped columns have been conducted over recent years. Although typical axial members are large-scale square/rectangular reinforced concrete (RC) columns in practice, the majority of such studies have concentrated on the behavior of small-scale circular concrete specimens. A high performance concrete, known as polymer concrete, made up of natural aggregates and an orthophthalic polyester binder, reinforced with non-metallic bars (glass reinforced polymer) has been studied. The material is described at micro and macro level, presenting the key physical and mechanical properties using different experimental techniques. Furthermore, a full description of non-metallic bars is presented to evaluate its structural expectancies, embedded in the polymer concrete matrix. In this paper, the mechanism of mechanical interaction of smooth and lugged FRP rods with concrete is presented. A general modeling and application of various elements are demonstrated. The contact parameters are defined and the procedures of calculation and evaluation of contact parameters are introduced. The method of calibration of the calculated parameters is presented. Finally, the numerical results are obtained for different bond parameters which show a good agreement with experimental results reported in literature.

• Health Policy and Management
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• v.30 no.4
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• pp.444-450
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• 2020

Background: In this study, we compared the incidents of humidifier disinfectants and incidents of mild hepatitis in Japan to highlight the differences in government response in the health care field in terms of "chain of responsibility". Methods: We examined whether the three mechanisms of action and the chain of responsibility hypothesis were applied to compare the cases of Korea and Japan. The incident of Japan occurred in 1987 in Misawa city, Aomori prefecture. In the 1990s, the safety of blood products increased dramatically. However, relief for infected victims was neglected. Green Cross did not notify the parties. In Korea, in the spring of 2011, a number of lung disease patients were accidentally admitted to a hospital in Seoul, and a female patient with respiratory failure symptoms expired. The Korea Centers for Disease Control and Prevention conducted animal tests and the Ministry of Health and Welfare issued an order for forced collection of humidifier disinfectants. Results: In the case of Japan, the Ministry of Health and Welfare had to take responsibility for follow-up measures such as the investigation of the cause, so it was tied to a "chain of responsibility". However, in the case of Korea, the Ministry of Health and Welfare was free from the chain. Conclusion: Through the comparison between the cases of Japan and Korea, we confirmed that whether or not a government organization chooses to conceal responsibility depends on its past behavior, which is whether it is free from the chain of responsibility or not. Therefore, it was reaffirmed that an organization (ministry or department) free from the chain of responsibility must exist within the government.

• Earthquakes and Structures
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• v.20 no.1
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• pp.71-86
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• 2021

This paper focuses on the development and assessment of the expected damage for the rocking response of rigid anchored blocks, with irregular geometry and non-uniform mass distribution, considering the site conditions and the seismicity of Mexico City. The non-linear behavior of the restrainers is incorporated to evaluate the pure tension and tension-shear failure mechanisms. A probabilistic framework is performed covering a wide range of block sizes, slenderness ratios and eccentricities using physics-based ground motion simulation. In order to incorporate the uncertainties related to the propagation of far-field earthquakes with a significant contribution to the seismic hazard at study sites, it was simulated a set of scenarios using a stochastic summation methods of small-earthquakes records, considered as Empirical Green's Function (EGFs). As Engineering Demand Parameter (EDP), the absolute value of the maximum block rotation normalized by the body slenderness, as a function of the peak ground acceleration (PGA) is adopted. The results show that anchorages are more efficient for blocks with slenderness ratio between two and three, while slenderness above four provide a better stability when they are not restrained. Besides, there is a range of peak intensities where anchored blocks located in soft soils are less vulnerable with respect to those located in firm soils. The procedure used in here allows to take decisions about risk, reliability and resilience assessment of different types of contents, and it is easily adaptable to other seismic environments.

• The Plant Pathology Journal
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• v.37 no.2
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• pp.87-98
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• 2021

To establish an infection, fungal pathogens must recognize diverse signals from host surfaces. The rice blast fungus, Magnaporthe oryzae, is one of the best models studying host-pathogen interactions. This fungus recognizes physical or chemical signals from the host surfaces and initiates the development of an infection structure called appressorium. Here, we found that protein MoAfo1(appressorium formation, MGG_10422) was involved in sensing signal molecules such as cutin monomers and long chain primary alcohols required for appressorium formation. The knockout mutant (ΔMoafo1) formed a few abnormal appressoria on the onion and rice sheath surfaces. However, it produced normal appressoria on the surface of rice leaves. MoAfo1 localized to the membranes of the cytoplasm and vacuole-like organelles in conidia and appressoria. Additionally, the ΔMoafo1 mutant showed defects in appressorium morphology, appressorium penetration, invasive growth, and pathogenicity. These multiple defects might be partially due to failure to respond properly to oxidative stress. These findings broaden our understanding of the fungal mechanisms at play in the recognition of the host surface during rice blast infection.

• Nuclear Engineering and Technology
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• v.54 no.8
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• pp.3095-3105
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• 2022

Solid Microencapsulated Fuel (SMF) is a type of solid fuel rod design that disperses TRISO coated fuel particles directly into a kind of matrix. SMF is expected to provide improved performance because of the elimination of cladding tube and associated failure mechanisms. This study focused on the neutronics and some of the fuel cycle characteristics of SMF by using OpenMC. Two kinds of SMFs have been designed and evaluated - fuel particles dispersed into a silicon carbide matrix and fuel particles dispersed into a zirconium matrix. A 7×7 fuel assembly with increased rod diameter transformed from the standard NHR200-II 9×9 array was also introduced to increase the heavy metal inventory. A preliminary study of two kinds of burnable poisons (Erbia & Gadolinia) in two forms (BISO and QUADRISO particles) was also included. This study found that SMF requires about 12% enriched UN TRISO particles to match the cycle length of standard fuel when loaded in NHR200-II, which is about 7% for SMF with increased rod diameter. Feedback coefficients are less negative through the life of SMF than the reference. And it is estimated that the average center temperature of fuel kernel at fuel rod centerline is about 60 K below that of reference in this paper.

• International Journal of Computer Science & Network Security
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• v.22 no.4
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• pp.274-284
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• 2022

By explaining the essence of corporate governance as well as disclosure and transparency, the study examined the guarantees of applying disclosure and transparency to firms listed on the Saudi stock exchange. The research also addressed the disclosure and transparency duties of firms listed on the Saudi stock exchange. Finance to prepare a prospectus, as the Capital Market Authority's regulations required that the prospectus includes information that enables the investor in securities to make his investment decision based on real foundations based on the issuing company's financial position and to ensure that companies fulfill that disclosure in the prospectus. Firms who fail to disclose are required by law to do so, and the Capital Market Authority's laws mandate companies listed on the financial market to regularly report fundamental events linked to the issuer or the securities issued by it. The Capital Market Authority must make it available to the public dealing with the business issuing the securities, and The Capital Market Authority's Law and Regulations have imposed fines on corporations that do not comply with disclosure and make the Board of Director's report available. The research focused on activities that the legislator deemed to be a breach of the obligation of openness, such as the danger of many measures aimed at ensuring the impartiality and transparency of trading in the Saudi financial market, as well as the absence of conflicts of interest. The research also addressed the sanctions imposed on The source for failing to meet the obligation of disclosure and openness, as well as the mechanisms of compensating persons harmed by the failure to meet that responsibility.

• Journal of Ginseng Research
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• v.47 no.2
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• pp.218-227
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• 2023

Background: Myocardial fibrosis (MF) is an advanced pathological manifestation of many cardiovascular diseases, which can induce heart failure and malignant arrhythmias. However, the current treatment of MF lacks specific drugs. Ginsenoside Re has anti-MF effect in rat, but its mechanism is still not clear. Therefore, we investigated the anti-MF effect of ginsenoside Re by constructing mouse acute myocardial infarction (AMI) model and AngII induced cardiac fibroblasts (CFs) model. Methods: The anti-MF effect of miR-489 was investigated by transfection of miR-489 mimic and inhibitor in CFs. Effect of ginsenoside Re on MF and its related mechanisms were investigated by ultrasonographic, ELISA, histopathologic staining, transwell test, immunofluorescence, Western blot and qPCR in the mouse model of AMI and the AngII-induced CFs model. Results: MiR-489 decreased the expression of α-SMA, collagenI, collagen III and myd88, and inhibited the phosphorylation of NF-κB p65 in normal CFs and CFs treated with AngII. Ginsenoside Re could improve cardiac function, inhibit collagen deposition and CFs migration, promote the transcription of miR-489, and reduce the expression of myd88 and the phosphorylation of NF-κB p65. Conclusion: MiR-489 can effectively inhibit the pathological process of MF, and the mechanism is at least partly related to the regulation of myd88/NF-κB pathway. Ginsenoside Re can ameliorate AMI and AngII induced MF, and the mechanism is at least partially related to the regulation of miR-489/myd88/NF-κB signaling pathway. Therefore, miR-489 may be a potential target of anti-MF and ginsenoside Re may be an effective drug for the treatment of MF.

• Steel and Composite Structures
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• v.47 no.6
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• pp.709-728
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• 2023

Experimental and analytical studies were conducted to clarify the influencing mechanisms of the longitudinal reinforcement on performance of axially loaded Reinforced Concrete-Filled Steel Tube (R-CFST) short columns. The longitudinal reinforcement ratio was set as parameter, and 10 R-CFST specimens with five different ratios and three Concrete-Filled Steel Tube (CFST) specimens for comparison were prepared and tested. Based on the test results, the failure modes, load transfer responses, peak load, stiffness, yield to strength ratio, ductility, fracture toughness, composite efficiency and stress state of steel tube were theoretically analyzed. To further examine, analytical investigations were then performed, material model for concrete core was proposed and verified against the test, and thereafter 36 model specimens with four different wall-thickness of steel tube, coupling with nine reinforcement ratios, were simulated. Finally, considering the experimental and analytical results, the prediction equations for ultimate load bearing capacity of R-CFSTs were modified from the equations of CFSTs given in codes, and a new equation which embeds the effect of reinforcement was proposed, and equations were validated against experimental data. The results indicate that longitudinal reinforcement significantly impacts the behavior of R-CFST as steel tube does; the proposed analytical model is effective and reasonable; proper ratios of longitudinal reinforcement enable the R-CFSTs obtain better balance between the performance and the construction cost, and the range for the proper ratios is recommended between 1.0% and 3.0%, regardless of wall-thickness of steel tube; the proposed equation is recommended for more accurate and stable prediction of the strength of R-CFSTs.

• Maritime Security
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• v.6 no.1
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• pp.137-161
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• 2023

This paper explores the limited role of alliances in preventing maritime territorial disputes among member states, using the ongoing conflict between Greece and Türkiye, two NATO allies, as a case study. Drawing on Institutionalist theory, we seek to explain the mechanisms that have contributed to the failure of the alliance to prevent this dispute, despite constant cooperation and transparency. Unlike land disputes, maritime territorial disputes are complex and multi-layered, with fluid boundaries that can change with climate or natural resource availability. Moreover, the lack of constant surveillance creates ambiguity about territorial encroachment thresholds. These factors have exacerbated the dispute between Greece and Türkiye, drawing other NATO members into the conflict and undermining the strength of the alliance. This paper concludes by providing policy implications for the Republic of Korea in its own potential maritime disputes, and contributes to the broader literature on the role of alliances in preventing territorial disputes.

• Steel and Composite Structures
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• v.50 no.1
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• pp.107-122
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• 2024

Following an internal column failure, adjacent double-span beams above the failed column will play a critical role in the load transfer and internal force redistribution within the remaining structure, and the span-to-depth ratios of double-span beams significantly influence the structural resistance capacity against progressive collapse. Most existing studies have focused on the collapse-resistant performances of single-story symmetric structures, whereas limited published works are available on the collapse resistances of multi-story steel frames with unequal spans. To this end, in this study, numerical models based on shell elements were employed to investigate the structural behavior of multi-story steel frames with unequal spans. The simulation models were validated using the previous experimental results obtained for single- and two-story steel frames, and the load-displacement responses and internal force development of unequal-span three-story steel frames under three cases were comprehensively analyzed. In addition, the specific contributions of the different mechanism resistances of unequal-span, double-span beams of each story were separated quantitatively using the energy equilibrium theory, with an aim to gain a deeper level of understanding of the load-resistance mechanisms in the unequal-span steel frames. The results showed that the axial and flexural mechanism resistances were determined by the span ratio and linear stiffness ratio of double-span beams, respectively.