• 제목/요약/키워드: Faculty

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Cytotoxic Constituents from the Stem Bark of Chisocheton pentandrus

  • Retnowati, Rurini;Sulistyarti, Hermin;Wahidah, Nikmatus Zahro;Syarifah, Anisa Lailatusy;Salam, Suprianto;Nurlelasari, Nurlelasari;Safari, Agus;Harneti, Desi;Tanjung, Mulyadi;Hidayat, Ace Tatang;Maharani, Rani;Supratman, Unang;Shiono, Yoshihito
    • Natural Product Sciences
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    • 제27권1호
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    • pp.18-27
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    • 2021

  • Eight cytotoxic constituents, consisting of six triterpenoids, cabralealactone (1), cabraleadiol (2), prototiamin A (3), 23-desmethyllimocin B (5), melianodiol (7) and indicalilacol (8) along with one limonoid, neemfruitins A (4) and one protolimonoid, protoxylocarpin G (6), were isolated from the extract of n-hexane of the stembark of Chisocheton pentandrus. The chemical structures were identified on the basis of spectroscopic evidence and compared to previously reported spectra. These isolated compounds appear for the first time in the plant. Compounds 1 - 8 were evaluated for their cytotoxic effect against MCF-7 breast cancer lines in vitro. Among the isolated compounds, melianodiol (7) showed the strongest cytotoxic activity with IC50 values of 16.8 µM.

  • https://doi.org/10.20307/nps.2021.27.1.18 인용 PDF KSCI

의과대학 교원 현황과 업적평가제도 특징 분석 (Current Status and Performance Evaluation Systems of Faculty in Korean Medical Schools)

  • 양은배;이태선;조명자
    • 의학교육논단
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    • 제21권1호
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    • pp.41-50
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    • 2019

  • The aim of this study is to analyze the current status and performance evaluation systems of faculty in Korean medical colleges and professional graduate medical schools (called medical schools). We developed a research tool based on previous studies and distributed it to 40 medical schools from July to October 2017. The response rate was 100%. We calculated the number of faculty members and analyzed the faculty evaluation systems and awareness according to national and private medical schools. As of 2017, the number of medical faculty in Korea was 11,111 (4,973 faculty were employed by their alma mater, which is 44.76% of the total), with non-medical doctor faculty accounting for 754 of the total. The medical schools reflect research achievements as most important for re-appointment and screening to promote faculty, and the area of education is secondary excepting clinical faculty of private medical schools. However, important issues in the faculty evaluation deal with the relevance of research achievement and the need for qualitative assessment. Some medical schools revised or have been revising the faculty evaluation system in areas such as minimum standards of education for promotion and separation of promotion and tenure review. Opening non-tenure track lines for faculty show positive effects such as increasing the number of positions for hire and easing the financial burdens of medical schools. Downfalls include inconsistencies between the responsibilities and actual practices of tenure not being available and the instability of faculty's status. In conclusion, medical schools need to prepare a faculty evaluation system that fits the position of faculty members and attempt to establish a reasonable compensation system.

  • https://doi.org/10.17496/kmer.2019.21.1.41 인용 PDF KSCI HTML