• Environmental Mutagens and Carcinogens
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• v.21 no.2
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• pp.106-112
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• 2001

In view of the effect of factor Ⅶ as a risk factor for essential hypertension, we investigated the length (I/D) polymorphism at position 323 promoter region and exon 8-Msp I RFLP of the human factor Ⅶ gene in the Korean patients with essential hypertension and normal controls. There were no significant differences in the allele, genotype and haplotype frequencies of these polymorphisms between normotensive and essential hypertensive subjects. The significant linkage disequilibrium was however, detected between two polymorphic sites. The Msp I RFLP and I/D polymorphism were also significantly associated with plasma triglyceride (TG) levels. Therefore, our results suggest that the significant association between two genetic variations in the human factor Ⅶ gene and plasma TG level may reflect the potential role of human factor Ⅶ gene as one of the genetic components for cardiovascular risk.

• Proceedings of the KIEE Conference
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• 2005.07a
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• pp.480-482
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• 2005

In this paper, utilization of load duration curves is presented for analyzing the effect of load power factor and determining the value of load power factor effectively. In addition, the power factor sensitivity of generation cost and integrated costs including voltage variation penalty cost are used for determining the value of the load power factor from the point of view of voltage regulation and economic investment. It is shown through the application to the KEPCO power system that the load power factor can be enhanced effectively and appropriately using the load duration curve.

• Transactions of Materials Processing
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• v.3 no.2
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• pp.215-228
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• 1994

The purpose of this paper is to pursue a general method to determine both the flow stress of a material and the friction factor by ring compression test. The materials are assumed to obey the expanded n-power hardening rule including the strain-rate effect. Ring compression is simulated by the rigid-plastic finite element method to obtain the database used in determining the flow stress and friction factor. The Simulation is conducted for various strain hardening exponent, strain-rate sensitivity, friction factor, and compressing speed, as variables. It is assumed that the friction factor is constant during the compression process. To evaluate the compatibility of the database, experiments are carried out at room and evaluated temperature using specimens of aluminum 6061-T6 under dry and grease lubrication condition. It is shown that the proposed test method is useful and easy to use in determining the flow stress and the friction factor.

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.12 no.2
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• pp.1-6
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• 1998

It is required to determine proper values for the maintenance factor according to traffic volume in the freeway lighting design. This paper presents a simple method to seperate of the effect of surrounding environment and that of traffic volume, which is based on the IESNA treatment with additional assumptions on their effects. Furthermore, it is found that prevailing concept for the maintenance factor does not necessarily yield a proper value for light loss factor, so that an additional factor of 0.9 should be included as an equipment factor.factor.

• Archives of Pharmacal Research
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• v.27 no.3
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• pp.324-333
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• 2004

To determine whether Insulin-like growth factor (IGF-I) treatment represents a potential means of enhancing the survival of cardiac muscle cells from adriamycin (ADR)-induced cell death, the present study examined the ability of IGF-I to prevent cell death. The study was performed utilising the embryonic, rat, cardiac muscle cell line, H9C2. Incubating cardiac muscle cells in the presence of adriamycin increased cell death, as determined by MTT assay and annexin V-positive cell number. The addition of 100 ng/mL IGF-I, in the presence of adriamycin, decreased apoptosis. The effect of IGF-I on phosphorylation of PI, a substrate of phosphatidylinositol 3-kinase (PI 3-kinase) or protein kinase B (AKT), was also examined in H9C2 cardiac muscle cells. IGF-I increased the phosphorylation of ERK 1 and 2 and $PKC{\;}{\zeta}{\;}kinase$. The use of inhibitors of PI 3-kinase (LY 294002), in the cell death assay, demonstrated partial abrogation of the protective effect of IGF-I. The MEK1 inhibitor-PD098059 and the PKC inhibitor-chelerythrine exhibited no effect on IGF-1-induced cell protection. In the regulatory subunit of PI3K-p85- dominant, negative plasmid-transfected cells, the IGF-1-induced protective effect was reversed. This data demonstrates that IGF-I protects cardiac muscle cells from ADR-induced cell death. Although IGF-I activates several signaling pathways that contribute to its protective effect in other cell types, only activation of PI 3-kinase contributes to this effect in H9C2 cardiac muscle cells.

• International Commerce and Information Review
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• v.10 no.2
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• pp.325-348
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• 2008

The purpose of this study is to find out the relationship between job fitness, organizational justice(distributive, procedural, interactional), job satisfaction, organizational trust, organizational commitment, and voluntary turnover intention in private organization such as in small fire in Korea. To identify the these relationships, the secondary data or past studies that were related with job fitness, organizational justice, job satisfaction, organizational trust, organizational commitment, voluntary turnover intention was collected and theoretically arranged. I made the theoretical proposed model to explain these relationships between the constructs, identify the operational definitions and 18 hypotheses was established, there was executed the survey of 262 in employees. Using the collected data, previous performances to confirm the construct validity and internal consistency by EFA(Exploratory Factor Analysis); i.e. factor analysis by SPSS, reliability by cronbach's a, and by the CFA(Confirmative Factor Analysis) and structural equations modelling the proposed model was tested by LISREL v. 8.52. The research came to the conclusions as follows: First, three perceived justice had the positive effect to the job satisfaction empirically. Second, procedural justice in three perceived justice only had the positive effect to the organizational trust empirically. Third, distributive justice in three perceived justice only had the positive effect to the organizational commitment empirically. Forth, job fitness had the positive effect to the organizational commitment, organizational trust, job satisfaction empirically in perspective. Fifth, I found the relationship between job satisfaction and organizational commitment, between job satisfaction and organizational trust was positive, between organizational commitment and trust. Finally, job satisfaction, organizational trust had not the positive effect directly, but indirect effect via organizational commitment was identified in voluntary turnover intention by empirical test.

• Korean journal of food and cookery science
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• v.27 no.2
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• pp.83-94
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• 2011

The purpose of this study was to analyze the structural relationships among selection attributes, satisfaction, and loyalty of green tea consumers, including their moderating effect of involvement. Questionnaires were administered to residents of Seoul and Gyeonggi-do province, who were 20 years old and older and who had purchased green tea. A total of 700 questionnaires were distributed, and 658 were finally used in the analysis. SPSS 15.0 and LISREL 8.80 were used for the analysis. Selection attributes had a significant effect on satisfaction, and statistical significance was observed with regard to factors such as marketing, production, sensory evaluation, and brand. No significant direct effect was observed between selection attributes and loyalty. Additionally, satisfaction had a significant effect on loyalty. The marketing factor had a negative effect on satisfaction in both the low- and high-involvement groups. The brand factor had a positive effect on satisfaction in the low involvement group, suggesting that developing and promoting a popular brand is essential. Sensory and utility factors had a positive effect on satisfaction in the high involvement group.

• The Journal of Korean Medicine
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• v.19 no.2
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• pp.50-58
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• 1998

The effects of the Evodiae fructus on the cardiovascular function were assessed in spontaneously hypertensive rats, and isolated preparation of spontaneously hypertensive rats aortic strip. In spontaneously hypertensive rats, intraperitoneal administration of methanol crude extract of Evodiae Fructus (0.5mg/kg) lowered aterial blood pressure which lasted for at least 4 hours. The hypotensive effect of Evodiae Fructus was more stronger with ${\alpha}-adrenoreceptor$ inhibitor(Phentholamine) and it was not affected by ${\beta}-adrenoreceptor$ inhibitor(Propranolol). The hypotensive effect of Evodiae Fructus was abolished by NAME. It is suggested that the hypotensive effect of Evodiae Fructus may be concern with endothelium-derived relaxing factor and it may be mediated through NO synthesis. Evodiae Fructus showed a vasorelaxing effect on denude aortic strip. It is suggested that Evodiae Fructus has a direct relaxing effect on vascular smooth muscle cells. Judging from above results, it was proved that hypotensive effect of Evodiae Fructus. The mechanism of hypotensive action may be concern with endothelium-derived relaxing factor and direct relaxing effect on vascular smooth muscle cells. Therefore, it is suggested that Evodiae Fructus is applicable to hypertension.

• International Journal of Advanced Culture Technology
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• v.6 no.1
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• pp.23-31
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• 2018

The purpose of this study was to identify mediating effect of major satisfaction in the effect of critical thinking disposition on disaster recognition. For this study, 237 students of nursing students from universities in Jeollanam do participated in the study. The data collection was collected on Dec 1 to 7, 2017. The descriptive statistics was used to analyze general characteristics of participants, the differences in disaster recognition according to general characteristics were analyzed by t-test or ANOVA. Regression analysis was conducted to confirm the effect of critical thinking disposition on disaster recognition and Baron, R.M. And Kenny, D.A.'s mediation effect statistic analysis was used to confirm the mediating effect of major satisfaction in critical thinking disposition on disaster recognition. As a result, the critical thinking disposition affects the disaster recognition, and it was judged that the major satisfaction was mediating role. intellectual fairness sub-factor showed perfect mediating effect and confidence and general truth sub-factor showed partial mediating effect. Based on the above findings, it can be seen that not only critical thinking but also satisfaction with the major should be considered in order to increase the recognition of the sudden disaster. In this case, research for linking critical thinking disposition and major satisfaction is likely to be meaningful. Through the results of this study, we suggest the program development of a linkage between critical thinking disposition and major satisfaction to increase the recognition of disaster.

• International Journal of Highway Engineering
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• v.14 no.6
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• pp.167-173
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• 2012

PURPOSES : This study is to develop speed correction factor for more realistic Level-of-Service(LOS) at multilane highway. METHODS : In this study, we compared speed difference the degree of speed reductions in actual multilane road conditions with speed reduction considering speed correction factor presented in highway capacity manual using statistical techniques. And also we presents new speed correction factor analyzing collected data at national highway No.1 (Goyang~Wolrung). RESULTS : The result of analyzing and comparing new suggested speed correction factor with speed correction factor in Korea Highway Capacity Manual (KHCM) shows RMSE (Root Mean Square Error) in new speed correction factor (RMSE 1.5) is much lower than existing speed correction factor (RMSE 13.4). New suggested speed correction can be used for analyzing Level-of-Service at multilane highway. And also we suggests improvements for analysis procedure in analyzing Level-of-Service at multilane highway CONCLUSIONS : As a result of comparing differences, we draw the causes that effect the differences in speed and suggest new speed correction factor that consider traffic volumes. It can be more rational because it uses speed correction factor which can consider more realistic traffic conditions, etc.