• International Journal of Contents
• /
• v.12 no.4
• /
• pp.31-44
• /
• 2016

Knowledge creation and management are regarded as critical success factors for an organization's survival in the knowledge era. As a process of knowledge acquisition and sharing, organizational learning mechanisms (OLMs) guide the learning function of organizations represented by its different learning activities. We examined a variety of learning processes that constitute OLMs. In this study, we aimed to capture the process and framework of OLMs and knowledge sharing and acquisition. Factors facilitating OLMs were investigated at three levels: individual, group, and organizational. The concept of an OLM has received some attention in the field of organizational learning, however, the relationship among the factors generating OLMs has not been empirically tested. As part of the ongoing discussion, we attempted a systemic approach for OLMs. OLMs can be represented by factors that are inherent to the organization's system; therefore, prior to empirically testing the OLM generating factor(s), evaluation of its organizational integration is required to determine effective treatment of each factor. Thus, we developed a framework to manage knowledge and proposed a method to numerically evaluate factors influencing the OLMs. Specifically, composite importance (CI) of the Decision-Making Trial and Evaluation Laboratory (DEMATEL) method was applied to explore the interaction effect of these factors based on systemic approach. The augmented matrix thus generated is expected to serve as a stochastic matrix of an absorbing Markov chain.

• Journal of the Korean Society of Clothing and Textiles
• /
• v.38 no.6
• /
• pp.913-928
• /
• 2014

This study estimated a dual path model to predict consumers' intention to use a QR code virtual store by the effect of a mobile transaction system and a facilitating condition that also examined the role of experience and the use of an intention model in the context of a QR code virtual store. A longitudinal field study was conducted at selected QR code virtual stores. A questionnaire containing mobile transaction system, facilitating condition, performance expectancy, effort expectance, and intention to use was administered at two different points in time: Initial use (T1) and the second use after one month (T2). This study sampled 109 subjects who voluntarily participated in field studies twice at different time points (pooled sample=218). Participants were asked to visit at the QR code virtual store and undertake shopping tasks on their smartphones. The estimated dual path model showed that a mobile transaction system had a positive effect on performance expectancy, which influenced intention to use; however, facilitating condition had a positive effect on effort expectancy, but the effort expectance did not lead to intention to use. The effort expectance significantly also affected the performance expectance influencing intention to use QR code virtual stores. It was also found that use experience moderated the effect of mobile transaction systems on performance expectancy. The findings discussed a critical and success factor in consumer technology acceptance and use over time. A managerial implication was also discussed to capture potential users by emphasizing performance expectancy with the superiority of an innovative system or consumer facilitating condition as external resources in the introduction stage of new technology.

• Journal of The Korean Association of Information Education
• /
• v.26 no.3
• /
• pp.175-186
• /
• 2022

This study has explored the facilitating factors affecting the learning persistence of university students and divided Emergency Remote Teaching(ERT) into two types based on its policies. The conclusions are as follows: First, perceived usefulness was the facilitating factor affecting learning persistence in Synchronous ERT. Therefore, learning persistence would improve by establishing various strategies such as exploring appropriate teaching strategies and building a stable infrastructure. Second, it was perceived usefulness, social presence, and system quality that were the facilitating factors affecting learning persistence in Asynchronous ERT. Thus, learning persistence would increase accompanied by immediate feedback, more active interaction, and so on.

• The Journal of Asian Finance, Economics and Business
• /
• v.9 no.7
• /
• pp.93-99
• /
• 2022

Nowadays, learning management systems (LMS) are an effective and efficient tool for providing students with a high-quality education. The current study examines the effect of different factors on the use of the blackboard application on mobile phones. The study selects four important factors after factor analysis, such as facilitating factor, performance factor, satisfaction factor, and difficulties factor. The data was collected through a structured questionnaire from 45 students as a sample in the college of business administration at Prince Sattam Bin Abdulaziz University. The study uses a logistic regression model to examine the empirical relationship between LMS adoption and different factors associated with blackboard adoption. The results show that 71 percent of the respondents are between the age of 18-20 years, and 100 percent of students have experience in using blackboard. The empirical results show that the satisfaction factor is positive and significant at the 10 percent level of significance and the difficulties factor is also positive and significant at the 1 percent level of significance. The results conclude that the students are satisfied with using the blackboard on mobile, nevertheless, the difficulties factor which is positive and significant shows that students are facing some difficulties in using the blackboard on their mobile.

• Asian Pacific Journal of Cancer Prevention
• /
• v.13 no.6
• /
• pp.2437-2444
• /
• 2012

Tumor metastasis remains the principal cause of treatment failure and poor prognosis in patients with colorectal cancer. It is a multistage process which includes proteolysis, motility and migration of cells, proliferation in a new site, and neoangiogenesis. A crucial step in the process of intra- and extra-vasation is the activation of proteolytic enzymes capable of degrading the extracellular matrix (ECM). In this stage, urokinase plasminogen activator receptor (uPAR) and matrix metalloproteinases (MMPs) are necessary. Micrometastases need the presence of growth factor and vascular growth factor so that they can form macrometastasis. In addition, cell adhesion molecules (CAMs) and guanine nucleotide exchange factors (GEFs) play important roles in the progression of colorectal cancer and metastatic migration. Further elucidation of the mechanisms of how these molecules contribute will aid in the identification of diagnostic and prognostic markers as well as therapeutic targets for patients with colorectal metastasis.

• Proceedings of the Technology Innovation Conference
• /
• 1997.07a
• /
• pp.83-123
• /
• 1997

The psychological work environments which facilitate technology innovations in organizations are divided into two dimensions of supportive work environments and challenging work environments. The confirmatory factor analysis confirmed the construct validity of two work environments. And simple and hierarchical regression analysis confirmed the significant effects of two work environments on motivations to the technology innovations. Therefore, Both of the challenging work environments(uncertainty of exta- organizational environments and tasks) and supportive work environments(managerial environments of intra-organizations) are the two important psychological work environments which facilitate technology innovations in organizations.

• Journal of Information Technology Applications and Management
• /
• v.27 no.1
• /
• pp.75-95
• /
• 2020

Smart Factory is the decisive factor of the Fourth Industrial Revolution and is a key field for national competitiveness. Until now, most smart factory research has focused on policy and technology. In order to spread more technology, it is necessary to study what factors influence the adoption of smart factory technology in the enterprise. Nevertheless, little research has been done. In this study, based on the UTAUT (Unified Theory of Acceptance and Use of Technology), which has been proved through many years of research, I have studied the factors that influence the acceptance of smart factory technology. As a result of research, performance expectancy, social influence, and facilitating conditions of UTAUT model had a positive(+) effect on behavior intention. Their relationship of influence was in the order of performance expectancy (β = .459)> facilitating conditions (β = .212)> social influence (β = .210). However, it was found that the effort expectancy did not affect the behavior intention, and the impact of the newly perceived risk on the behavior intention to use was not confirmed. The main reason is that the acceptance of smart factory technology is not a matter of personal interest but a matter of organizational choice. Trust, on the other hand, was found to be partially mediated between performance expectancy, facilitating conditions, social influence and behavior intention. For many years, many researchers have validated the UTAUT, which has been validated through various empirical studies. It is academically meaningful to begin the study of factors affecting the acceptance of smart factory technology in terms of the UTAUT. In practice, it is necessary to provide SME employees with more information related to the introduction of smart factories, to provide advanced services related to the establishment of smart factories, and to establish a standardized model for each industry.

• Journal of Distribution Science
• /
• v.16 no.6
• /
• pp.65-75
• /
• 2018

Purpose - The exhibition is one of the critical distribution channels that leads to mass sales of products. Servicescape is considered as an effective means facilitating consumers' purchasing behavior. The objective of this research is to examine the effects of servicescape of the exhibition on consumer's purchasing behavior measured by time spent, the number of consultations, the number of items purchased, and amount of money spent. Research design, data, and methodology - Servicescape was divided into four main components: 'spatial layout/functionality', 'ambient condition', 'design/artifacts', and 'human factor'. Based on previous studies, this study hypothesized that servicescape dimensions first influence consumer's shopping duration and the number of consultations which in turn, affects consumer's actual purchase. A total of 407 samples were collected from attendees in Baby Expo taken place in Kyunggido, South Korea. The data were used to assess overall fit of the proposed model and test hypotheses using structural equation modeling. All the constructs had acceptable levels of composite reliability and convergent and discriminant validity. Results - The results showed that except for 'spatial layout/functionality', all components of servicescape had a significant influence on consumer's shopping duration in the exhibition. Except for 'design/artifacts', other factors of servicescape did not show a significant effect on 'the number of consultations'. Interestingly, 'design/artifacts' exerted a significant negative effect on 'the number of consultations'. As expected, 'time spent' and 'number of consultations' showed significant effects on both 'the number of items purchased' and 'amount of money spent'. Conclusions - The results offer some insights into the effect of servicescape on facilitating consumers' purchasing behavior in the context of the exhibition. Theoretically, this study provides a new type of conceptual framework that verifies the relationships between not only servicescape and purchasing behavior, but also purchasing behavior-related variables. In addition, this study supports the concept of a dark side of servicescape. With regards to practical implications, this study suggests that exhibition organizers should put more efforts in facilitating consumer's desire to stay. More importantly, organizers need to keep in mind that excessive emphasis on 'design/artifacts' to increase consumers' shopping duration can cause a side effect that reduces opportunities for interactions with customers.

• Journal of Korean Society for Quality Management
• /
• v.49 no.3
• /
• pp.359-374
• /
• 2021

Purpose: This study attempted to verify which factor affects the intention to use of the connected car that has recently emerged. Methods: Based on prior researches, this study derives the characteristics of connected car that affects user intention and designs research model for empirical analysis. A structured questionnaire was conducted for those who drive cars, and a total of 292 usable responses were collected and empirically analyzed using SPSS and PLS. Results: The results of this study are as follows; service quality, hedonic motivation, and social influence have a significant effect on perceived value, but system quality, information quality, user innovation, experience and facilitating condition did not. In addition, it was found that system quality, information quality, service quality, user innovation, facilitating conditions and social influence have a significant effect on satisfaction, but hedonic motivation and experience did not affect satisfaction. Conclusion: The findings of this empirical analysis have implications for effectively recognizing the value of connected cars based on the technology of information systems to users and establishing sustainable growth strategies for connected car producers and suppliers.

• Molecules and Cells
• /
• v.46 no.3
• /
• pp.142-152
• /
• 2023

Nuclear factor erythroid 2-related factor 2 (Nrf2) mediates the cellular antioxidant response, allowing adaptation and survival under conditions of oxidative, electrophilic and inflammatory stress, and has a role in metabolism, inflammation and immunity. Activation of Nrf2 provides broad and long-lasting cytoprotection, and is often hijacked by cancer cells, allowing their survival under unfavorable conditions. Moreover, Nrf2 activation in established human tumors is associated with resistance to chemo-, radio-, and immunotherapies. In addition to cancer cells, Nrf2 activation can also occur in tumor-associated macrophages (TAMs) and facilitate an anti-inflammatory, immunosuppressive tumor immune microenvironment (TIME). Several cancer cell-derived metabolites, such as itaconate, L-kynurenine, lactic acid and hyaluronic acid, play an important role in modulating the TIME and tumor-TAMs crosstalk, and have been shown to activate Nrf2. The effects of Nrf2 in TIME are context-depended, and involve multiple mechanisms, including suppression of proinflammatory cytokines, increased expression of programmed cell death ligand 1 (PD-L1), macrophage colony-stimulating factor (M-CSF) and kynureninase, accelerated catabolism of cytotoxic labile heme, and facilitating the metabolic adaptation of TAMs. This understanding presents both challenges and opportunities for strategic targeting of Nrf2 in cancer.