• Title/Summary/Keyword: FUNCTIONAL GROUPS

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Hypoglycemic Effect of the Functional Food Manufactured by Fermented Soybean as Main Materials in Streptozotosin - Induced Diabetic Rats (Streptozotocin 유발 당뇨쥐에 있어서 발효콩을 주원료로 한 기능성 식품의 혈당강하 효과)

  • 최승필;최형택;이효진;문선영;김수현;이범구;이득식;함승시
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.33 no.7
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    • pp.1126-1132
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    • 2004
  • The present study was undertaken to evaluate the effect of functional food, which was processed with fermented soybean as main ingredient (FS), on the body weight, organ weight, plasma glucose, and plasma lipid in diabetic rats caused by streptozotocin (STZ). The body weight was decreased more slowly in the FS group than in the diabetic, and the food intake increased significantly in all diabetic groups. The food efficiency was very low in all diabetic groups, but increased significantly in the FS groups than diabetic control (p<0.05). In comparing the weight of organ, the weight of liver and kidney were increased in all diabetic groups than in the control, and decreased slightly in FS groups. The weight of heart and spleen were not different among all test groups. In the oral glucose tolerance test, the blood glucose in the diabetic group was the highest in 60 minutes. And the blood glucose in the FS group was the highest in 30 minutes, and decreased significantly after 120 minutes to the level of fasting glucose. The glucose in serum was decreased significantly in the FS groups fed the functional food for 4 weeks, compared to the diabetic control (p<0.05). Total cholesterol, triglyceride and atherogenic index (AI) in serum were significantly higher in diabetic control, compared to the normal (p<0.05), and decreased by 16.4%, 15.4% and 48.3%, respectively, in the FS fed 400 mg/kg of functional food. HDL-cholesterol was increased significantly in the FS-400, compared to the diabetic control. These results support that functional food using fermented soybean improve glucose and lipid metabolism in diabetic rats.

Effect of Acid Treatments on Hydrogen Storage Behaviors of Ordered Mesoporous Carbons (화학적 산처리가 중기공 탄소체의 수소저장거동에 미치는 영향)

  • Lee, Seul-Yi;Park, Soo-Jin
    • 한국신재생에너지학회:학술대회논문집
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    • 2010.06a
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    • pp.229.1-229.1
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    • 2010
  • We investigated the effect of chemical acid treatments on hydrogen storage behaviors of the ordered mesoporous carbons (MCs). The surface functional groups and specific elements of the MCs were characterized with Fourier Transform Infrared (FT-IR) spectrometry and X-ray photoelectron spectroscopy (XPS). Also, the changes in the surface functional groups of the MCs were quantitatively detected by Boehm's titration method. The structural properties of the MCs were investigated using X-ray diffraction (XRD). The hydrogen adsorption capacity of the MCs was evaluated by means of adsorption isotherms at 77 K/1 bar. The formation of surface functional groups by the acidic treatments could influence on the hydrogen storage capacity of the MCs.

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Chemical synthesis of processable conducting polyaniline derivative with free amine functional groups

  • Kar, Pradip
    • Advances in materials Research
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    • v.3 no.2
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    • pp.117-128
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    • 2014
  • Processable conducting polyaniline derivative with free amine functional groups was successfully synthesized from the monomer o-phenylenediamine in aqueous hydrochloric acid medium using ammonium persulfate as an oxidative initiator. The synthesized poly(o-phenylenediamine) (PoPD) in critical condition was found to be completely soluble in common organic solvents like dimethyl sulfoxide, N,N-dimethyl formamide etc. From the intrinsic viscosity measurement, the optimum condition for the polymerization was established. The polymer was characterized by ultraviolet visible spectroscopy, Fourier transform infrared spectroscopy, proton magnetic resonance spectroscopy ($^1HNMR$) and thermogravimetric (TGA) analyses. The weight average molecular weights of the synthesized polymers were determined by the dynamic light scattering (DLS) method. From the spectroscopic analysis the structure was found to resemble that of polyaniline derivative with free amine functional groups attached to ortho/meta position in the phenyl ring. However, very little ladder unit was also present with in the polymer chain. The moderate thermal stability of the synthesized polymer could be found from the TGA analysis. The average DC conductivity of $2.8{\times}10^{-4}S/cm$ was observed for the synthesized polymer pellet after doping with hydrochloric acid.

Pervaporation of aqueous organic mixture through in situ complex membranes based on polycrylonitrile

  • Lee, Young-Moo;Oh, Boo-Keun
    • Proceedings of the Membrane Society of Korea Conference
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    • 1995.09a
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    • pp.39-55
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    • 1995
  • Modified polycrylonitrile(PAN) membranes were prepared by emulsion or emulsifier-free emulsion polymerization technique. Separation capacity was determined at several operating temperatures(25, 40, 55 and 70 $^{\circ}$C) to dehydrate 56wt% pyridine aqueous solution through modified PAN membranes having different functional groups. All these PAN-based membranes were selective toward water to different degrees depending on the nature of functional groups present in the membranes. Pervaporation characteristics of PAN-based membranes are so different and classified into three categories depending on the type of the functional groups in PAN copolymers. Among PAN-based membranes, the in-situ complex membranes show the best separation capacity over the operating temperatures.

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Structural Arrangement for Functional Requirements of Brain Recombinant 4-Aminobutyrate Aminotransferase

  • Sung, Bo-Kyung;Kim, Young-Tae
    • BMB Reports
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    • v.33 no.1
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    • pp.43-48
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    • 2000
  • 4-Aminobutyrate aminotransferase is a key enzyme of the 4-aminobutyric acid shunt. It converts the neurotransmitter 4-aminobutyric acid to succinic semialdehyde. In order to study the structural and functional aspects of catalytically active Cys residues of pig brain 4-aminobutyrate aminotransferase, we purified the active form in E. coli by coproduction of thioredoxin. The structural arrangement for functional requirements of a dimeric protein using a bifunctional sultbydryl reagent was then characterized, and the spatial proximity between the essential SH groups and a cofactor (pyridoxal-5'-phosphate) binding site was determined. The bifunctional sultbydryl reagent DMDS reacted with the enzyme at the ratio of one molecule per enzyme dimer. This resulted in an approximately 50% loss of enzymatic activity. The spatial proximity of the distance between the essential SH groups and the cofactor-binding site was determined by the energy transfer measurement technique. The result (approximate 20 ${\AA}$) suggested that cross-linking of two sulfhydryl groups with DMDS is not near a PLP binding site.

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Dielectric Polymers for OTFT Application

  • Choi, Sung-Lan;Kim, Yeon-Ok;Kim, Hong-Doo
    • Journal of Information Display
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    • v.11 no.3
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    • pp.95-99
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    • 2010
  • A series of new dielectric polymers with phenyl, epoxy, and carboxylicacid functional groups was prepared via free-radical polymerization. The effect of such dielectric polymers with various functional groups on the performance of OTFT was investigated. The nonpolar groups of terpolymer made the surface of the dielectric layer more hydrophobic and improved the crystal growth of pentacene on the gate insulator, resulting in higher mobility. By controlling the functional group, the electric characteristics of OTFT performance was varied, with $0.00017-0.15\;cm^2/V{\cdot}s$ mobility.

Influence of Plasma Treatment on Hydrogen Chloride Removal of Activated Carbon Fibers

  • Park, Soo-Jin;Kim, Byung-Joo;Ryu, Seung-Kon
    • Carbon letters
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    • v.5 no.3
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    • pp.103-107
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    • 2004
  • The atmospheric pressure plasma treatments ($Ar/O_2$ and $Ar/N_2$) of activated carbon fibers (ACFs) were carried out to introduce hydrophilic functional groups on carbon surfaces in order to enhance the hydrogen chloride gas (HCl) adsorption. Surface properties of the ACFs were determined by XPS and SEM. $N_2$/77 K adsorption isotherms were investigated by BET and D-R (Dubinin-Radushkevich) plot methods. The HCl removal efficiency was confirmed by HCl detecting tubes (range:1~40 or 40~1000 ppm). As experimental results, it was found that all plasma-treated ACFs showed the decrease in the pore volume, but the HCl removal efficiency showed higher level than that of the untreated ACFs. This result indicated that the plasma treatments led to the conformation of hydrophilic functional groups on the carbon surfaces, resulting in the increase of the interaction between the ACFs and HCl gas.

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Activated Carbons as Electrode Materials in Electric Double-Layer Capacitors I. Electrochemical Properties of Activated Carbons in Relation to their Porous Structures and Surface Oxygen Functional Groups

  • Kim, Chang-Hee;Pyun, Su-Il
    • Journal of the Korean Ceramic Society
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    • v.40 no.9
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    • pp.819-826
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    • 2003
  • This article is concerned with the overview of activated carbons as electrode materials in electric double-layer capacitors. Firstly, this article introduced various types of activated carbons with their precursors and manufacturing conditions which can be divided into two main steps of the carbonization and activation processes. Secondly, the present article gave the detailed discussion about the porous structures and examined previous works on the electrochemical behaviors of activated carbons in relation to their porous structures, along with our recent works. Finally, this article characterized the surface oxygen functional groups and presented their influence on the electrochemical properties of activated carbons by reviewing our recent results.

Analytic Study of 68 Patients with Functional Dyspepsia According to Syndrome Differentiation (68명의 기능성 소화불량증 환자에 대한 한의학적 변증분석)

  • Park, Yang-Chun;Cho, Jung-Hyo;Choi, Sun-Mi;Son, Chang-Gue
    • The Journal of Internal Korean Medicine
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    • v.29 no.3
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    • pp.574-581
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    • 2008
  • Objective : Functional dyspepsia is a common disease impeding subjective quality of life. The present study aimed to analyze syndrome differentiation of functional dyspepsia to help with development of oriental therapeutics. Methods : Sixty-eight subjects diagnosed with functional dyspepsia were analyzed and classified into one of five syndrome differentiations. We compared symptomatic characteristics according to the Nepean Dyspepsia Index (NDI), such as severity, kinds of dyspepsia-related complaints and functional dyspepsia quality of life (QOL) among groups. Results : Patients with disharmony between liver and stomach were most prevalent (52.9%), but no patients with complex of fever and cold. The scores of symptom severity and QOL were not significantly different between groups. Each group had a specified pattern of complaints. Conclusions : Clinical-study based analysis of functional dyspepsia constructed by this study, could be useful in objectively developing Oriental medicines for this disease.

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The Effect of Low, High Frequency Electroacupuncture on Functional Dyspepsia: A Randomized, Double Blinded, Two Arm Trial (기능성 소화불량증에 대한 저빈도, 고빈도 전침의 효능 비교 연구: 무작위배정, 이중맹검(피험자, 평가자), 평행군 설계)

  • Yeo, In Ho;Lee, Eun Yong;Lee, Cham Kyul
    • Journal of Acupuncture Research
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    • v.31 no.3
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    • pp.19-24
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    • 2014
  • Objectives : The purpose of this study is to investigate the efficacy of the electroacupuncture with different frequency on functional dyspepsia. Methods : We observed 30 functional dyspepsia patients from May, 2013 to June, 2014. This study was randomized and double blinded. The patients were divided into two groups. One group(group A) was treated with 3 Hz electroacupuncture and the other group(group B) was treated with 300 Hz electroacupuncture. We evaluated the treatment effect of each group by using visual analogue scale(VAS) and pressure algometer. Results : 1. Functional dyspepsia was significantly improved in group treated with 3 Hz electroacupuncture. 2. Functional dyspepsia was significantly improved in group treated with 300 Hz electroacupuncture. 3. As a result of evaluation there were no statistical significance between two groups. Conclusion : Both 3 Hz and 300 Hz electroacupuncture has significant effect on functional dyspepsia. But there is no significant difference between 3 Hz and 300 Hz electroacupuncture.