• Title/Summary/Keyword: FFS

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Effect of Donor Cell Types and Passages on Preimplantation Development and Apoptosis in Porcine Cloned Embryos

  • Lee, Youn-Su;Ock, Sun-A;Cho, Seong-Keun;Jeon, Byeong-Gyun;Kang, Tae-Young;Balasubramanian, S.;Choe, Sang-Yong;Rho, Gyu-Jin
    • Asian-Australasian Journal of Animal Sciences
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    • v.20 no.5
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    • pp.711-717
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    • 2007
  • In this study, two cell types from porcine females, namely fetal fibroblasts (pFFs) and adult ear fibroblasts (pAEFs) and two passages (3-4 and 7-8) were investigated by evaluating the development rate, blastocyst cell number and the incidence of apoptosis. No significant differences were observed in the cleavage rates of cloned and IVF embryos. The blastocyst rates between the embryos cloned with pFFs ($15.1{\pm}3.2$) and pAEFs ($10.4{\pm}2.6$) did not differ significantly but was significantly (p<0.05) lower in pAEFs than that in IVF ($22.5{\pm}4.5$) embryos. Total cell number in pFFs ($28.4{\pm}4.3$) and pAEFs cloned blastocysts ($24.2{\pm}5.1$) was significantly (p<0.05) lesser than IVF control ($35.4{\pm}3.2$). Apoptosis rates between cloned blastocysts differed significantly (p<0.05) and were significantly (p<0.05) higher than IVF embryos. The blastocyst rates between the cloned embryos cloned with different cell passages did not differ significantly but in embryos cloned with 7-8 cell passage was significantly (p<0.05) lower than the IVF control. Apoptosis signals were detected in IVF and cloned embryos as early as day 3 and the rates of apoptosis increased concurrently with the embryo development. In conclusion, high apoptosis during in vitro preimplantation development resulted in low development rate and total cell number of cloned embryos. Moreover, based on the apoptotic incidence in cloned blastocysts, fetal fibroblasts are more suitable for production of cloned embryos in porcine.

Impact of DRG Payment on the Length of Stay and the Number of Outpatient Visits After Discharge for Caesarean Section During 2004-2007 (DRG 지불제도가 재원일수와 퇴원 후 외래방문일수에 미치는 영향: 2004-2007년도 제왕절개술을 중심으로)

  • Shon, Chang-Woo;Chung, Seol-Hee;Yi, Seon-Ju;Kwon, Soon-Man
    • Journal of Preventive Medicine and Public Health
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    • v.44 no.1
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    • pp.48-55
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    • 2011
  • Objectives: The purpose of this study was to examine the impact of Diagnosis-Related Group (DRG)-based payment on the length of stay and the number of outpatient visits after discharge in for patients who had undergone caesarean section. Methods: This study used the health insurance data of the patients in health care facilities that were paid by the Fee-For-Service (FFS) in 2001-2004, but they participated in the DRG payment system in 2005-2007. In order to examine the net effects of DRG payment, the Difference-In-Differences (DID) method was adopted to observe the difference in health care utilization before and after the participation in the DRG payment system. The dependent variables of the regression model were the length of stay and number of outpatient visits after discharge, and the explanatory variables included the characteristics of the patients and the health care facilities. Results: The length of stay in DRG-paid health care facilities was greater than that in the FFS-paid ones. Yet, DRG payment has no statistically significant effect on the number of outpatient visits after discharge. Conclusions: The results of this study that DRG payment was not effective in reducing the length of stay can be related to the nature of voluntary participation in the DRG system. Only those health care facilities that are already efficient in terms of the length of stay or that can benefit from the DRG payment may decide to participate in the program.

Variation in hospital length of stay according to the DRG-based prospective payment system in the voluntarily participating providers (DRG(Diagnosis-Related Group)를 이용한 포괄진료비 지불제도의 선택 참여에 따른 재원일수 변화)

  • Choi, Sook-Ja;Kwon, Soon-Man;Kang, Gil-Won;Moon, Sang-Jun;Lee, Jin-Seok
    • Health Policy and Management
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    • v.20 no.2
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    • pp.17-39
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    • 2010
  • This study explored the impact on the DRG(Diagnosis-Related Groups)-based prospective payment system(PPS) operated by voluntarily participation providers. We analyzed whether the provides in the DRG-based PPS and in traditional fee-for-service(FFS) systems showed different the degree of variation in length of stay(LOS), and the providers' behaviors depending on the differences according to the varied participation periods. The study sample included all data 2,061 institutions participated in DRG-PPS in 2007 and all cases 473 FFS institutions which reported fee-for-service claims were reviewed same diagnosized diseases at least 10cases claims during three months We compared the differences of the LOS among health care institutions according to their type, region, and size. For DRGs showing significant differences in LOS, multiple regression analyses were performed to find out factors associated with LOS and interaction effect participation and hospital types or participation periods. The result provide the evidence that the DRG payment system operated by volunteering health care institutions had impact on resources use, which can reduce the institutions' the length of stay. While some DRGs had no correlation between participation periods and LOS, other DRGs, DRG participation period reversely linear relationship with LOS. That is to say, the longer participation year, the less reducing the LOS. These results support the future expansion of the DRG-based PPS plan to all health care services in Korea.

Test Generation for Partial Scanned Sequential Circuits Based on Boolean Function Manipulation (논리함수처리에 의한 부분스캔순차회로의 테스트생성)

  • Choi, Ho-Yong
    • The Transactions of the Korea Information Processing Society
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    • v.3 no.3
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    • pp.572-580
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    • 1996
  • This paper describes a test generation method for sequential circuits which improves the application limits of the IPMT method by applying the partial scan design to the IPMT method. To solve the problem that the IPMT method requires enormous computation time in image computation, and generates test patterns after the partialscan design is introduced to reduce test complexity. Scan flip-flops are selected for the partial scan design according to the node size of the state functions of a sequential circuit in their binary decision diagram representations. Experimental results on ISCAS'95 benchmark circuits show that a test generator based on our method has achieved 100% fault coverage by use of either 20% scan FFs for s344, s349, and s420 or 80% scan FFs for sl423. However, test gener-ators based on the previous IPM method have not achieved 100% fault coverage for those circuits.

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The predictive value of serum myeloma protein in solitary plasmacytoma

  • Chang, Won Ick;Koh, Hyeon Kang;Yoon, Sung-Soo;Kim, Han-Soo;Eom, Keun-Yong;Kim, Il Han
    • Radiation Oncology Journal
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    • v.38 no.2
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    • pp.129-137
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    • 2020
  • Purpose: To identify the clinical usefulness of serum M protein and to establish a rationale for regular follow-up with serum protein electrophoresis in solitary plasmacytoma. Materials and Methods: Sixty-nine patients with solitary plasmacytoma and solitary plasmacytoma with minimal marrow involvement according to the International Myeloma Working Group criteria were retrospectively reviewed. Results: At a median follow-up of 6.2 years, 5-year local control (LC), 5-year multiple myeloma-free survival (MMFS), 5-year failure-free survival (FFS), and 5-year overall survival (OS) were 82.6%, 44.1%, 41.8%, and 85.1%, respectively. Among the patients whose initial serum M protein was present or not evaluated, 37.3% of patients showed disappearance of serum M protein after various treatment. MMFS of these patients were comparable to non-secretory plasmacytoma with undetectable levels of M protein, and significantly better than patients with persistent M protein. Increase of serum M protein ≥0.1 g/dL was most predictive of treatment failure with area under the curve of 0.731. Conclusion: Patients who eventually showed persistence of serum M protein after treatment showed worse MMFS and FFS compared to those whose serum M protein disappeared or who had initially non-secretory disease. The increase of serum M protein level ≥0.1 g/dL from current nadir was predictive of treatment failure. Therefore, regular follow-up with serum M protein is highly recommended especially unless the patient had initially non-secretory disease.

Evaluation and treatment of facial feminization surgery: part I. forehead, orbits, eyebrows, eyes, and nose

  • Dang, Brian N.;Hu, Allison C.;Bertrand, Anthony A.;Chan, Candace H.;Jain, Nirbhay S.;Pfaff, Miles J.;Lee, James C.;Lee, Justine C.
    • Archives of Plastic Surgery
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    • v.48 no.5
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    • pp.503-510
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    • 2021
  • Facial feminization surgery (FFS) incorporates aesthetic and craniofacial surgical principles and techniques to feminize masculine facial features and facilitate gender transitioning. A detailed understanding of the defining male and female facial characteristics is essential for success. In this first part of a two-part series, we discuss key aspects of the general preoperative consultation that should be considered when evaluating the prospective facial feminization patient. Assessment of the forehead, orbits, hairline, eyebrows, eyes, and nose and the associated procedures, including scalp advancement, supraorbital rim reduction, setback of the anterior table of the frontal sinus, rhinoplasty, and soft tissue modifications of the upper and midface are discussed. In the second part of this series, bony manipulation of the midface, mandible, and chin, as well as soft tissue modification of the nasolabial complex and chondrolaryngoplasty are discussed. Finally, a review of the literature on patient-reported outcomes in this population following FFS is provided.

Development and Validation of Dynamic Model for KC-100 UAS (KC-100 항공기 무인화를 위한 운동모델 구축 및 검증)

  • Seong Hyeon Kim;Ji Bon Kim;Jung Hoon Lee;Eung Tai Kim;Byoung Soo Kim
    • Journal of Aerospace System Engineering
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    • v.17 no.1
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    • pp.79-87
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    • 2023
  • To design a control law of an aircraft, an accurate aircraft dynamic model is required. To obtain an aerodynamic database (DB) to build a dynamic model, a large number of wind tunnel tests are typically required. However, when flight test data of target aircraft exist such as in the process of unmanned conversion of a manned aircraft, an aircraft dynamic model can be obtained through a parameter estimation method and a DB tuning procedure. This paper describes a nonlinear model construction process and a verification method for KC-100 OPV aircraft. Flight data compatibility analysis was performed to determine suitability of the estimation method application. Linear model estimation was performed using the maximum likelihood estimation method. Results of aerodynamic DB tuning process and verification applying the FFS standard to the nonlinear model constructed are presented.

Design of an Intelligent Ambulatory Monitoring System Using Flash Memory Card (Flash Memory Card를 이용한 Intelligent Ambulatory Monitoring 시스템 설계)

  • Song, G.K.;Lee, K.J.;Yoon, H.R.
    • Proceedings of the KOSOMBE Conference
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    • v.1997 no.05
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    • pp.330-333
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    • 1997
  • In this paper, we designed a low power and small-sized, light weighted intelligent ambulatory monitoring system using a flash memory card. The system's hardware specifications are as follows: 2 channels, 8bit/250Hz sampling rate, 20M byte storage capacity, a single-chip microcontroller (68HC11E9). To easily interface with PC based system, FFS(Flash File System) was used. We obtained the QRS detection rate of 99.14 through the evaluation with MIT/BIH database.

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A Study on the Color Performance of FFS Mode Using the Various Analysis Methods

  • Park, Se-Hong;Park, Eun-Jung;Han, Sang-Hun;Park, Jong-Gyun;Park, In-Cheol;Lee, Kyung-Ha;Lee, Jung-Yeal
    • 한국정보디스플레이학회:학술대회논문집
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    • 2006.08a
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    • pp.691-694
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    • 2006
  • So far, we have done much research improving quality of LCD TV. Recently, we have developed 26" WXGA LCD TV by advance fringe field switching (AFFS) technology with smooth and every scene realistic in color image that obtained from the amazing authentic color delivery, optical characteristic and fast response time. Our upgrade device has shown the brightness over 600nits (Color shift <0.015 and Transmittance ratio > 5.5%), gray to gray response time under 6ms, contrast ratio over 1200:1 and viewing angle over 178/178, respectively. And also, motion artifacts improved by fast response of LC with low viscosity, cell gap and dielectric constant.

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Cell Gap Dependent Transmission Characteristic of the Fringe-Field Switching Mode in a LC with Negative Dielectric Anisotropy

  • Kim, H.Y.;Kim, J.M.;Song, S.H.;Lee, S.K.;Lim, Y.J.;Jung, S.H.;Lee, S.H.
    • 한국정보디스플레이학회:학술대회논문집
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    • 2003.07a
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    • pp.539-542
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    • 2003
  • We have studied cell gap-dependent electrode-optic characteristics of the FFS mode using the LC with negative dielectric anisotropy. In case of a small cell gap of 2 ${\mu}m$, the transmittance at the center of pixel and common electrodes is low due to stronger influence of surface anchoring that holds the LC to the initial state than twisting force induced by neighboring LCs. In case of a large cell gap of 4 ${\mu}m$, the influence of surface anchoring force becomes weak so that the LCs at the center of pixel and common electrode can be twisted enough by applied voltage, giving rise to high transmittance. Therefore, we conclude that the light efficiency in the device is dependent on the cell gap.

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