• Title/Summary/Keyword: FELIX

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Natural Dye Extraction from Merbau (Intsia bijuga) Sawdust: Optimization of Solid-Solvent Ratio and Temperature

  • Aswati MINDARYANI;Ali SULTON;Felix Arie SETIAWAN;Edia RAHAYUNINGSIH
    • Journal of the Korean Wood Science and Technology
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    • v.51 no.6
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    • pp.481-492
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    • 2023
  • The ecofriendly lifestyle has attracted considerable support for sustainable development. Natural dyes, as sustainable products, have become a research focus and development area for many scientists. Ecofriendly processing also supports circular sustainable development. This study effectively obtained tannins as a natural dye from merbau (Intsia bijuga) sawdust using water as an ecofriendly solvent. Merbau sawdust is an underutilized industrial waste. Temperature and solid-solvent ratio variations were performed to extract tannins from merbau sawdust. Temperature and solid-solvent ratio positively affected solution yield and tannin concentration. The optimal condition was identified using response surface methodology and experimental observations. A yield of 0.2217 g tannins/g merbau was obtained under the conditions of 333.15 K and 0.125 solid-solvent ratio. Extraction was controlled by convective mass transfer at the interface of solid particles.

The SPIZWURZ project - Experimental investigations and modeling of the behavior of hydrogen in zirconium alloys under long-term dry storage conditions

  • Mirco Grosse;Felix Boldt;Michel Herm;Conrado Roessger;Juri Stuckert;Sarah Weick;Daniel Nahm
    • Nuclear Engineering and Technology
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    • v.56 no.3
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    • pp.824-831
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    • 2024
  • In order to investigate the occurring processes during long-term dry storage of spent fuel assemblies, a joined project called SPIZWURZ, between the Karlsruhe Institute of Technology and the Gesellschaft für Anlagen-und Reaktorsicherheit (GRS), was started. Aim of the SPIZWURZ project is the determination and quantification of the influence of texture and elastic strain on diffusion and solubility of hydrogen in three different zirconium alloys used in western Europe during a long-term cooling transient (1 K/d) starting at 400 ℃. The strain in the cladding of an irradiated spent fuel rod shall be measured. Models predicting the formation of radial oriented hydrides will be validated, improved, and implemented in the GRS fuel rod performance code TESPA-ROD. This paper describes the SPIZWURZ project and already obtained first results.

Progress in the Direct Application of Pharmacogenomics to Patient Care: Sustaining innovation

  • Burckart, Gilbert J.;Frueh, Felix W.;Lesko, Lawrence J.
    • Proceedings of the Korean Society of Applied Pharmacology
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    • 2006.11a
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    • pp.23-39
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    • 2006
  • The application of the knowledge from the Human Genome Project to clinical medicine will be through both industrial drug development and the application of pharmacogenomics (PG) to patient care. The slow uptake of clinical innovations into clinical practice can be frustrating, but understanding the history of acceptance and sustaining medical innovation is critically important to position PG to succeed. This primarily means that PG tests must have legitimacy; they must be thoroughly validated, must be cost-effective, must be widely accepted by medical practitioners, must be supported by public policy, and must have a way of being easily incorporated into current medical practice. They must also lead to actionalble decisions by health care providers for their patients. Innovative PG assays should be tested in the best US laboratories, and reimbursement for testing must be accepted at the federal and state level. The companies providing these PG tests should be capable of supporting the interpretation and use of the test throughout medical practice. Advances such as the addition of PG information to drug labeling and the routine use of validated biomarkers to determine choice of cancer chemotherapy have been made. The PG research community must pay attention to the principles that have been previously described for acceptance and sustaining medical innovations in order for PG to be widely accepted in clinical medical practice.

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Damage Tolerant Design for the Tilt Rotor UAV (틸트 로터형 무인항공기의 손상허용 설계)

  • Park, Young Chul;Im, Jong Bin;Park, Jung Sun
    • Journal of Aerospace System Engineering
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    • v.1 no.2
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    • pp.27-36
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    • 2007
  • The Damage Tolerant Design is developed to help alleviate structural failure and cracking problems in aerospace structures. Recently, the Damage Tolerant Design is required and recommended for most of aircraft design. In this paper, the damage tolerant design is applied to tilt rotor UAV. First of all, the fatigue load spectrum for the tilt rotor UAV is developed and fatigue analysis is performed for the flaperon joint which has FCL (fatigue critical location). Tilt rotor UAV has two modes: helicopter mode when UAV is taking off and landing; fixed wing mode when the tilt rotor UAV is cruising. To make fatigue load spectrum, FELIX is used for helicopter mode. TWIST is used for fixed wing mode. Fatigue analysis of flaperon joint is performed using fatigue load spectrum. E-N curve approach is used for picking crack initiation point. The LEFM(Linear Elastic Fracture Method) is considered for analyzing crack growth or propagation. Finally, including the crack initiation and propagation, the fatigue life is evaluated. Therefore the Damage Tolerant Design can be done.

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Progress in the Direct Application of Pharmacogenomics to Patient Care: Sustaining innovation

  • Frueh, Felix W.;Lesko, Lawrence J.;Burckart, Gilbert J.
    • Biomolecules & Therapeutics
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    • v.15 no.1
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    • pp.1-6
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    • 2007
  • The application of the knowledge from the Human Genome Project to clinical medicine will be through both industrial drug development and the application of pharmacogenomics (PG) to patient care. The slow uptake of clinical innovations into clinical practice can be frustrating, but understanding the history of acceptance and sustaining medical innovation is critically important to position PG to succeed. This primarily means that PG tests must have legitimacy; they must be thoroughly validated, must be cost-effective, must be widely accepted by medical practitioners, must be supported by public policy, and must have a way of being easily incorporated into current medical practice. They must also lead to actionalble decisions by health care providers for their patients. Innovative PG assays should be tested in the best US laboratories, and reimbursement for testing must be accepted at the federal and state level. The companies providing these PG tests should be capable of sup-porting the interpretation and use of the test throughout medical practice. Advances such as the addition of PG information to drug labeling and the routine use of validated biomarkers to determine choice of cancer chemotherapy have been made. The PG research community must pay attention to the principles that have been previously described for acceptance and sustaining medical innovations in order for PG to be widely accepted in clinical medical practice.

Performance of Fusarium oxysporum EKT01/02 isolate in cyanide biodegradation system

  • Akinpelu, Enoch Akinbiyi;Adetunji, Adewole Tomiwa;Ntwampe, Seteno Karabo Obed;Nchu, Felix;Mekuto, Lukhanyo
    • Environmental Engineering Research
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    • v.23 no.2
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    • pp.223-227
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    • 2018
  • This study reports a cyanide resistant and/or tolerant fungus, isolated from the rhizosphere of Zea mays contaminated with cyanide-based pesticides. The isolate was characterised using molecular biology. The effect of free cyanide and heavy metals on the growth of isolate in a synthetic gold mine wastewater was examined. The molecular analyses identified the isolate as Fusarium oxysporum EKT01/02 (KU985430/KU985431). The isolate had a free cyanide degradation efficiency of 77.6%. The results indicated greater growth impairment in culture containing Arsenic (optical density 1.28 and 1.458) and cyanide (optical density 1.315 and 1.385). Higher growth was observed in all cultures supplemented with extracellular polymeric substance. This study showed that the isolate possesses wide substrate utilisation mechanism that could be deployed in environmental engineering applications.

A Case of Tsutsugamushi Disease (경북지방에서 발견된 Tsutsugamushi 병 치험 1례)

  • Park, Shie-Hwoa;Yoon, Sung-Chul;Lee, Young-Hyun;Chung, Jae-Chun;Kim, Chong-Suhi;Hong, Seok-Il
    • Journal of Yeungnam Medical Science
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    • v.4 no.1
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    • pp.173-176
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    • 1987
  • Tsutsugamushi disease is an acute, febrile, typhus-like disease of rural Asia transmitted by the bite of larval trombiculid mites. The disease is caused by infection with Rickettsia tsutsugamushi. Recently the authors experienced a case of tsutsugamushi disease which was serologically confirmed. Here we reports a case of tsutsugamushi disease which successfully managed with doxycycline and reviewed literatures on it briefly.

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Research on Disney's 3D Animation 's Style, Layout Pipeline, and Camer a Capture System

  • Paik, Jiwon;Kim, Cheeyong
    • Journal of Korea Multimedia Society
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    • v.16 no.11
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    • pp.1348-1356
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    • 2013
  • Disney Animation has showed not only artistic excellence but also technological innovations through a lot of animation films that they released. Especially with the unique concept that free-willed game characters dive into different worlds of games in animation film, received both critical and commercial acclaim for its stunning visuals and outstanding CG (computer graphics) effects. The purpose of this study is to analyze different styles of game worlds, Disney's layout pipeline, and in-house camera capture system used in . This paper analyzes that three game worlds in this film such as Fix-It Felix Jr., Sugar Rush, and Hero's Duty express different styles by using appropriate character animation and camera movements. Especially Hero's Duty game which new in-house camera capture system is extensively used maximizes unseen visuals by perfectly making realistic and believable game world. Disney's newly developed in-house camera capture system, which is used in this film for the first time, allows real camera's motion and shake and real-time camera's movement and correction within animation set. Result of this study proves that this system improves directing of feature animation and enhance efficiency of the layout department's production process. Therefore, it contributes to a great extent to development of animation films' business.

Controlling size and magnetic properties of Fe3O4 clusters in solvothermal process

  • Madrid, Sergio I. Uribe;Pal, Umapada;Jesus, Felix Sanchez-De
    • Advances in nano research
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    • v.2 no.4
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    • pp.187-198
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    • 2014
  • Magnetite nanoparticles (MNPs) of different sizes were synthesized by solvothermal process maintaining their stoichiometric composition and unique structural phase. Utilizing hydrated ferric (III) chloride as unique iron precursor, it was possible to synthesize sub-micrometric magnetite clusters of sizes in between 208 and 381 nm in controlled manner by controlling the concentration of sodium acetate in the reaction mixture. The sub-micrometer size nanoclusters consist of nanometric primary particles of 19 - 26.3 nm average size. The concentration of sodium acetate in reaction solution seen to control the final size of primary MNPs, and hence the size of sub-micrometric magnetite nanoclusters. All the samples revealed their superparamagnetic behavior with saturation magnetization ($M_s$) values in between 74.3 and 77.4 emu/g. $M_s$. The coercivity of the nanoclusters depends both on the size of the primary particles and impurity present in them. The mechanisms of formation and size control of the MNPs have been discussed.