• 제목/요약/키워드: FAT4 protein

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Dietary Soy Protein and Calcium Reduce Serum Lipid and Cholesterol in Rats Fed Eat-Enriched Diets

  • Lee, Yeon-Sook;Jung, Eun-Hee
    • Preventive Nutrition and Food Science
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    • 제7권4호
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    • pp.367-372
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    • 2002
  • This study investigated the effects of dietary soy protein and Ca on the lipid profiles of rats fed fat-enriched diets. Rats were divided into two groups and fed either a casein-low Ca (Exp I) or ISP-high Ca diet (Exp II) for a control period of 4 weeks. The two groups of rats were again subdivided into 4 groups and fed one of 4 experimental diets for another 4 weeks. The experimental diets consisted of 18% beef tallow and 1 % cholesterol, in which either 20 % casein or ISP with one of two levels of Ca, high (1 %) or low (0.1 %). The concentrations of total lipid, cholesterol and triglyceride in serum, liver and feces were determined. At the end of the control period, the serum total lipid and cholesterol concentrations were low in the rats fed ISP-high Ca diet (67~76% and 83~86%). During the next 4 week period, these concentrations remained significantly lower in rats fed the diets containing ISP and high Ca compared with those on casein and low Ca diets (p < 0.05). Total lipid and cholesterol concentrations in feces were significantly higher in the ISP-high Ca dietary group at 4 weeks, and high in both high Ca groups at 8 weeks. This study demonstrates that both soy protein and Ca reduce serum and liver cholesterol, triglyceride, and total lipid in rats fed fat-enriched diet, and that they have an additive effect when combined.

Effects of Caloric Restriction on Endocrine Functions and Body Fat Distribution in Overweight Premenopausal Women, Related to their UCP3 (Uncoupling Protein 3) Genotypes

  • Lee, Jong-Ho;Kim, Oh-Yoen;Kim, Ji-Young;Park, Kyoung;Yangsoo Jang
    • Nutritional Sciences
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    • 제5권1호
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    • pp.13-19
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    • 2002
  • A mutation in the promoter region of uncoupling protein 3 (UCF3), specifically the -55C longrightarrow T transition, may influence an individual's energy metabolism and body weight. The objective of this study was to investigate the effect of a weight reduction program on endocrine functions and body fat distribution, related to UCP3 promoter genotype. Ninety overweight pre-menopausal female subjects participated in the weight reduction program at Yonsei University Hospital, and were placed on a calorie-restricted diet (300 kcal less than their daily requirements) for 12 weeks. After 12 weeks, all subjects on the program lost approximately 5% of their initial body weights and had lower Body Mass Index (BMI) values. Among the 90 women, 56 had a normal (without mutation) UCP3 genotype, while 34 women had mutations in the promoter region of UCP3. Despite similar weight reductions in both groups, a significantly higher decrease in abdominal adipose tissue was observed in the normal UCP3 genotype group, compared to the group with mutations. In particular, there was a significant reduction of fat at the lumbar 1 (Ll) level in the without-mutation group. Serum levels of total cholesterol, apolipoprotein Al were significantly decreased in the without-mutation group, by 4.4% and 5.7% respectively. Serum levels of hormones were not significantly changed in both groups artier the intervention. However, in the group without the mutations, the leptin level significantly reduced by 23.4% (p<0.001). Serum free fatty acid (FFA) concentration was significantly increased in the group with mutation following the weight reduction program. On the other hand, FFA responses were shown similar increases in both groups. In conclusion, although no difference was found in the magnitude of weight reduction in both groups, there were significant differences in body fat distribution and in endocrine function between the groups.

The Quality Characteristics of Salted Ground Pork Patties Containing Various Fat Levels by Microwave Cooking

  • Jeong, Jong Youn;Lim, Seung Taek;Kim, Cheon Jei
    • 한국축산식품학회지
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    • 제36권4호
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    • pp.538-546
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    • 2016
  • This study was carried out to evaluate the effects of fat level on the microwave cooking properties of ground pork patties with NaCl (1.5%). Ground pork patties were processed from pork hams to achieve fat levels of 10%, 15%, 20%, and 25%, respectively. Each patty was cooked from a thawed state to 75℃ in a microwave oven at full power (700 W). After microwave cooking, protein content, moisture content, fat retention, and shear force values in patties decreased as fat level increased from 10 to 25%. As fat level increased, cooking time decreased but total cooking loss and drip loss were increased, whereas slight differences in diameter reduction and thickness of patties were observed. In raw patties, 10% fat patties had lower L* values and higher a* values compared to patties with more fat, but these differences were reduced when patties were cooked. Patties with 10% fat showed a more pink color on the surface and interior than patties with a higher fat content but more air pockets were noted in higher-fat patties. Higher-fat patties were more tender, juicy, and oily than lower-fat patties.

Effect of Fat Level and the Ripening Time on Quality Traits of Fermented Sausages

  • Yim, Dong-Gyun;Jang, Kyoung-Hwan;Chung, Ku-Young
    • Asian-Australasian Journal of Animal Sciences
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    • 제29권1호
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    • pp.119-125
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    • 2016
  • The objective of this study was to investigate the effect of the fat reduction on the physicochemical and microbiological characteristics of fermented sausages during ripening and drying. Low fat fermented sausages were produced with different fat levels (30%, 20%, 10%, and 5%) under ripening conditions and fermented process. Samples from each treatment were taken for physicochemical and microbiological analyses on the 0, 1, 2, 3, 4, 5, 7, 10, 14, and 21st day of ripening. In proximate analysis, the fat reduction in sausages produced an increase in moisture, protein and ash contents during ripening and drying (p<0.05). The weight losses were significantly higher in high fat formulations during the first 4 days, whereas those were higher in low fat ones after 10 days of storage (p<0.05). Fat reduction was responsible for an increase in shear force values after 3 days of storage. The volatile basic nitrogen (VBN) value of the low fat samples was significantly higher (p<0.05). Low fat sausages reduced the extent of lipid oxidation. The lower fat level produced redder sausages. Total plate bacteria and Pseudomonas counts of sausages showed no significant differences. Production of low fat sausages resulted in the physicochemical and microbiological attributes equal to or better than the high fat sausages without negative effects, except only a higher VBN and weight loss.

맥류(麥類)의 가공(加工)에 관(關)한 연구(硏究) (Studies on the Milling of Barley, Naked-barley & Wheat)

  • 김희갑
    • 한국식품과학회지
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    • 제10권2호
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    • pp.109-111
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    • 1978
  • 보리, 쌀보리, 밀등 3종(種)의 국산맥류(國産麥類)를 공시(公試)하여 도정(搗精)과 제분(製粉)의 두가지 가공방법(加工方法)으로 가공수율(加工收率) 60%, 70%, 80%, 90%의 네 수준(水準)으로 나누어 회분(灰分), 단백질(蛋白質), 지질(脂質) 섬유질(纖維質), Calcium, 철분(鐵分), Thiamine등의 함유율(含有率)을 분석(分析) 조사(調査)하였던바 다음과 같은 결과(結果)를 얻었다. 1) 가공(加工)된 곡물(穀物)의 회분(灰分), 단백질(蛋白質), 지질(脂質), 섬유질(纖維質), Calcium, 철분(鐵分), Thiamine등의 함유율(含油率)은 도정(搗精)의 경우 제분(製粉)의 경우에 다 같이 가공수율(加工收率)과 정비례관계(正比例關係)에 있었다. 2) 겉보리에서는 도정(搗精)한 것이 제분(製粉)한 것에 비(比)해 평균적(平均的)으로 동일(同一)한 가공수율(加工收率)에서 회분(灰分)은 0.83%, 단백질(蛋白質)은 1.31%, 지질(脂質)은 0.40%, 섬유질(纖維質)은 0.75%, Calcium은 3.03mg%, 철분(鐵分)은 2.40mg%, Thiamine은 0.14mg%가 낮았다. 3) 쌀보리에서는 도정(搗精)한 것이 제분(製粉)한 것에 비(比)해 평균적(平均的)으로 동일(同一)한 가공수율(加工收率)에서 회분(灰分)은 0.41%, 단백질(蛋白質)은 1.96%, 지질(脂質)은 0.33%, 섬유질(纖維質)은 0.84%, Calcium은 4.54mg%, 철분(鐵分)은 1.19mg%, Thiamine은 0.10mg%가 낮았다. 4) 밀에서는 도정(搗精)한 것이 제분(製粉)한 것에 비(比)해 평균적(平均的)으로 동일(同一)한 가공수율(加工收率)에서 회분(灰分)은 0.28%, 단백질(蛋白質)은 2.25%, 지질(脂質)은 0.05%, 섬유질(纖維質)은 0.25%, Calcium은 4.31mg%, 철분(鐵分)은 0.12mg%, Thiamine은 0.15mg%가 높았다.

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Gene expression of fatty acid binding protein genes and its relationship with fat deposition of Thai native crossbreed chickens

  • Tunim, Supanon;Phasuk, Yupin;Aggrey, Samuel E.;Duangjinda, Monchai
    • Animal Bioscience
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    • 제34권4호
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    • pp.751-758
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    • 2021
  • Objective: The objectives of this study were to investigate the relationship between the mRNA expression of adipocyte type fatty acid binding protein (A-FABP) and heart type FABP (H-FABP) in Thai native chicken crossbreeds and evaluate the level of exotic inclusion in native chicken that will improve growth while maintaining its relatively low carcass fat. Methods: The fat deposition traits and mRNA expression of A-FABP and H-FABP were evaluated at 6, 8, 10, and 12 weeks of age in 4 chicken breeds (n = 8/breed/wk) (100% Chee breed [CH] [100% Thai native chicken background], CH male and broiler female [Kaimook e-san1; KM1] [50% CH background], broiler male and KM1 female [Kaimook e-san2; KM2] [25% CH background], and broiler [BR]) using abdominal fat (ABF) and muscular tissues. Results: The BR breed was only evaluated at 6 weeks of age. At week 6, the CH breed had a significantly lower A-FABP expression in ABF and intramuscular fat (IF) compared with the other breeds. At 8 to 12 weeks, the KM2 groups showed significant upregulation (p<0.05) of A-FABP in both ABF and IF compared to the CH and KM1 groups. The expression of H-FABP did not follow any consistent pattern in both ABF and IF across the different ages. Conclusion: Some level of crossbreeding CH chickens can be done to improve growth rate while maintaining their low ABF and IF. The expression level of A-FABP correlate with most fat traits. There was no consistency of H-FABP expression across breed. A-FABPs is involved in fat deposition, genetic markers in these genes could be used in marker assisted studies to select against excessive fat accumulation.

Expressional Patterns of Adipocyte-Associated Molecules in the Rat Epididymal Fat during Postnatal Development Period

  • Lee, Ki-Ho;Kim, Nan Hee
    • 한국발생생물학회지:발생과생식
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    • 제22권4호
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    • pp.351-360
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    • 2018
  • The adipogenesis is a maturation process of pre-adipocyte cell into mature lipid-filled adipocyte cell. The adipogenesis begins at the late prenatal stage and continues until the early postnatal age. Because the adipogenesis and formation of adipose tissue persist during postnatal period and are precisely regulated by the action of numerous gene products, the present research was attempted to determine the expressional patterns of adipose tissue-associated genes in the rat epididymal fat pad at different postnatal ages, from 7 days to 2 years of ages, using a quantitative real-time PCR analysis. The basal expression levels of CCAAT/enhancer binding protein gamma, sterol regulatory element binding transcription factor 1, fatty acid binding protein 4, adiponectin, leptin, and resistin at the early postnatal ages were significantly lower than those at the elderly ages, even though a fluctuation of expressional levels was observed at some ages. The lowest expressional level of delta like non-canonical Notch ligand 1 was detected at 44 days and 5 months of ages. The expression of peroxisome proliferator-activated receptor gamma ($PPAR{\gamma}$) was the highest at 44 days of age, followed by a diminished expression of $PPAR{\gamma}$ at the elderly ages. These results indicate the existence of a complex regulatory mechanism(s) for expression of adipose tissueassociated genes in the rat epididymal fat during postnatal period.

젖소에서 유성분 분석을 통한 영양상태 평가 및 건강관리에 관한 연구 IV. 고능력우 위주의 대규모 목장에서 분만 후 첫 번째 유검정 성적과 제4위전위 질병과의 관련성 (Studies on health management and nutritional evaluation by milk components analysis in Holstein cows IV. The relationship between milk composition from the first test within 35 days in milk and displaced abomasum in a large dairy herd of high yielding Holstein cows)

  • 문진산;손창호;주이석;강현미;장금찬;김종만
    • 대한수의학회지
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    • 제41권3호
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    • pp.407-412
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    • 2001
  • Milk data may be increasingly used as indicators of the protein-energy balance and actual farm feeding practices. It was related to milk production, nutritional and reproductive disorders. The purpose of this study was to investigate the relationship between level of fat, protein or milk urea nitrogen (MUN) from the first test within 35 days in milk and displaced abomasum (DA) in a large dairy herd with high yielding Holstein cows. Milk data from forty-five DA cases were compared to those from 90 healthy cows. Higher odds of DA diagnosis was found with higher 5.0% milk fat, lower 3.0% milk protein. Therefore, cows with a fat to protein ratio of>1.5 had higher risks for DA. Also, incidence rates of DA was higher in the cows which the level of MUN was lower than 12.0 mg/dl or higher than 25.0 mg/dl relative to healthy cows. These results indicate that cows diagnosed with DA were energy deficient prior to DA diagnosis. We conclude that level of fat, protein or MUN serve as a monitoring tool of protein and energy nutritional balance in early lactation cows and also as a significant predictor of risk for DA.

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육계의 생산에 있어 단백질수준 및 급여시기에 관한 연구 (Effects of Different Protein Levels and Time of Change from Starter to Finisher Ration on the Performance of Broilers)

  • 김현조;오세정
    • 한국가금학회지
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    • 제14권1호
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    • pp.15-24
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    • 1987
  • 본 시험은 육계사료의 단백질수준 및 급여시기가 육계의 생산성에 미치는 효과를 구명하기 위하여 전기와 후기사료의 단백질수준을 각각 22%와 20%, 20%와 18%로 하고 전후기사료의 교체시기를 2, 4 및 6주령으로 하는 6개처리에 육계초생추 216수를 공시하여 1984년 12월 14일부터 1985년 2월 8일까지 8주간에 걸쳐 축산시험장에서 시험을 실시한 결과를 요약하면 다음과 같다. 1. 증체량은 단백질수준이 높을수록 증가하였으며, 전후기사료의 교찬시기가 빠를수록 점차 감소하였지만 사료교체시기에서 4주령과 6주령 간에는 차이가 없었다. 2. 사료섭취량은 처리간에 차이가 없었으며, 사료요구율은 전후기 사료의 단백질수준 22% 및 20%를 4주령 또는 6주령에 교체했을 때 가장 유리하였다. 3. 단위증체당 단백질요구량은 단백질수준이 높아질수록 증가하였다. 4. 육성율은 단백질수준이나 교찬시기에 의하여 영향을 받지 않았다. 5. 도체율은 처리간에 차이가 없었지만 복강지방 축적율은 단백질수준이 증가할수록, 그리고 교체시기가 늦어질수록 점차 감소하였다. 6. 수당소득은 전후기사료의 단백질수준 22% 및 20%를 4주령에 교체한 처리에서 가장 높았다. 이상의 결과를 종합해서 볼 때 육계 전기 및 후기사료의 단백질수준은 각각 22%와 20%, 교체시기는 4주령이 적합할 것으로 사료된다.

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Effect of Feeding High Forage Diets with Supplemental Fat on Blood Metabolites, Rumen Fermentation and Dry Matter Digestibility in Dairy Cows

  • Abdullah, M.;Young, J.W.;Tyler, H.D.;Mohiuddin, G.
    • Asian-Australasian Journal of Animal Sciences
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    • 제13권4호
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    • pp.451-456
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    • 2000
  • Fifty mid-lactation Holstein cows were used in a six-week feeding trial to study effects of high-forage, and high-fat diets on blood constituents, rumen fermentation and dry matter digestibility. Cows were divided into 10 replicates, each consisting of five cows. Each cow was assigned to a control (diet 1) or one of the four experimental diets (high-forage (75%), high-fat (7.5%) (diet 2); high-forage. medium-fat (5.0%) (diet 3); medium forage (65%), high-fat (diet 4); medium-forage, medium-fat (diet 5)), or a control diet containing about 50% forage and 2% fat. All diets were isonitrogenous (17.7% crude protein). The forage mixture consisted of 20% alfalfa hay, 40% alfalfa haylage, and 40% corn silage. Supplemental fat included 80% rumen-protected fat and 20% yellow grease. A non-significant difference was observed in concentrations of blood glucose for cows on different experimental and control diets. Plasma nonesterified fatty acids (NEFA) were higher in cows consuming experimental diets than those consuming the control diet. However, differences in NEFA concentrations in the plasma of cows consuming diets with different forage and fat levels were not significant. Rumen pH, concentration of volatile fatty acids (VFA) in rumen contents, and dry matter digestibility of control and experimental diets, and diets with different levels of forage and supplemental fat did not differ significantly.