• Journal of Veterinary Science
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• v.24 no.4
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• pp.51.1-51.17
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• 2023

Background: To date, various genotypes of infectious bronchitis virus (IBV) have co-circulated and in Korea, GI-15 and GI-19 lineages were prevailing. The spike protein, particularly S1 subunit, is responsible for receptor binding, contains hypervariable regions and is also responsible for the emerging of novel variants. Objective: This study aims to investigate the putative major amino acid substitutions for the variants in GI-19. Methods: The S1 sequence data of IBV isolated from 1986 to 2021 in Korea (n = 188) were analyzed. Sequence alignments were carried out using Multiple alignment using Fast Fourier Transform of Geneious prime. The phylogenetic tree was generated using MEGA-11 (ver. 11.0.10) and Bayesian analysis was performed by BEAST v1.10.4. Selective pressure was analyzed via online server Datamonkey. Highlights and visualization of putative critical amino acid were conducted by using PyMol software (version 2.3). Results: Most (93.5%) belonged to the GI-19 lineage in Korea, and the GI-19 lineage was further divided into seven subgroups: KM91-like (Clade A and B), K40/09-like, QX-like (I-IV). Positive selection was identified at nine and six residues in S1 for KM91-like and QX-like IBVs, respectively. In addition, several positive selection sites of S1-NTD were indicated to have mutations at common locations even when new clades were generated. They were all located on the lateral surface of the quaternary structure of the S1 subunits in close proximity to the receptor-binding motif (RBM), putative RBM motif and neutralizing antigenic sites in S1. Conclusions: Our results suggest RBM surrounding sites in the S1 subunit of IBV are highly susceptible to mutation by selective pressure during evolution.

• Journal of Venture Innovation
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• v.6 no.3
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• pp.73-93
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• 2023

This study provides a prospect for the fast growing the smartwatch market by investigating the relationship between the satisfaction and the continuous use intention of Apple watch users, as well as the factors influencing their satisfaction. Based on the TAM, this study uses system quality, information quality, and self-efficacy as independent variables, perceived usefulness, perceived ease of use, and satisfaction as mediators, and continuous use intention as the dependent variable. We analyze the data of 256 individuals who completed an online survey with SPSS 26.0 and AMOS 26.0 software. This study conducts several tests and analyses to empirically evaluate the data including reliability analysis, factor analysis, feasibility analysis, path analysis, hypothesis verification, and mediation analysis. Our results investigate which factors may influence consumers' intention to continuously using Apple Watch devices in the future. In summary, satisfaction has a positive effect on the intention to continuously use smartwatchs. Perceived usefulness and perceived ease of use have a positive effect on satisfaction. Among the three factors (system quality, information quality, and self-efficacy), only self-efficacy has no significant impact on perceived usefulness but had a positive effect on perceived ease of use. In addition, system quality and information quality positively affect perceived usefulness, perceived ease of use, satisfaction, and continuous intention to use an Apple Watch. Taking the Apple Watch as the subject of our research topic, this study provides theoretical value by exploring the impact of user's satisfaction with their smartwatch on their continuous usage intention. This study further explains the influence of system quality, information quality, and self-efficacy on user satisfaction. Additionally, this research offers valuable insight to practitioners by confirming that information quality, system quality, and self-efficacy are important features for enhancing satisfactory user experiences which in turn may increase users' intention to continued using smartwatches.

• Animal Bioscience
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• v.37 no.6
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• pp.1001-1006
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• 2024

Objective: This study aimed to investigate the effect of Codonopsis pilosula polysaccharide (CPP) on the motility, mitochondrial integrity, acrosome integrity rate, and antioxidant ability of sheep sperm after preservation at 4℃. Methods: Semen from healthy adult rams were collected and divided into four groups with separate addition of 0, 200, 400, and 1,000 mg/L CPP. Sperm motility was analyzed using the Computer-Assisted Semen Analysis software after preservation at 4℃ for 24, 72, 120, and 168 h. Sperm acrosome integrity rate was analyzed by Giemsa staining at 24, 72, and 120 h, and mitochondrial membrane integrity was analyzed by Mito-Tracker Red CMXRos. The total antioxidant capacity (T-AOC) and malondialdehyde (MDA) content of spermatozoa were measured after 120 h of preservation. Results: The sperm viability and forward-moving sperm under 200 mg/L CPP were significantly higher than that in the control group at 72 h (61.28%±3.89% vs 52.83%±0.70%, 51.53%±4.06% vs 42.84%±1.14%), and 168 h (47.21%±0.85% vs 41.43%±0.37%, 38.68%±0.87% vs 31.68%±0.89%). The percentage of fast-moving sperm (15.03%±1.10% vs 11.39%±1.03%) and slow-moving sperm (23.63%±0.76% vs 20.29%±1.11%) in the 200 mg/L group was significantly higher than control group at 168 h. The mitochondrial membrane integrity of the sperm in the group with 200 mg/L CPP was significantly higher than those in the control group after storage at 4℃ for 120 h (74.76%±2.54% vs 65.67%±4.51%, p<0.05). The acrosome integrity rate in the group with 200 mg/L (87.66%±1.26%) and 400 mg/L (84.00%±2.95%) was significantly higher than those in the control group (80.65%±0.16%) after storage for 24 h (p<0.05). CPP also increased T-AOC and decreased the MDA concentration after preservation at 4℃ (p<0.05). Conclusion: Adding CPP could improve the T-AOC of sperm, inhibit lipid peroxidation, and facilitate semen preservation.

• Journal of KIISE:Computing Practices and Letters
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• v.13 no.5
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• pp.293-299
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• 2007

Intelligent pipeline inspection gauges (PIGs) are inspection vehicles that move along within a (gas or oil) pipeline and acquire signals (also called sensor data) from their surrounding rings of sensors. By analyzing the signals captured in intelligent PIGs, we can detect pipeline defects, such as holes and curvatures and other potential causes of gas explosions. There are two major data access patterns apparent when an analyzer accesses the pipeline signal data. The first is a sequential pattern where an analyst reads the sensor data one time only in a sequential fashion. The second is the repetitive pattern where an analyzer repeatedly reads the signal data within a fixed range; this is the dominant pattern in analyzing the signal data. The existing PIG software reads signal data directly from the server at every user#s request, requiring network transfer and disk access cost. It works well only for the sequential pattern, but not for the more dominant repetitive pattern. This problem becomes very serious in a client/server environment where several analysts analyze the signal data concurrently. To tackle this problem, we devise a fast in-memory cache manager, called T-Cache, by considering pipeline sensor data as multiple time-series data and by efficiently caching the time-series data at T-Cache. To the best of the authors# knowledge, this is the first research on caching pipeline signals on the client-side. We propose a new concept of the signal cache line as a caching unit, which is a set of time-series signal data for a fixed distance. We also provide the various data structures including smart cursors and algorithms used in T-Cache. Experimental results show that T-Cache performs much better for the repetitive pattern in terms of disk I/Os and the elapsed time. Even with the sequential pattern, T-Cache shows almost the same performance as a system that does not use any caching, indicating the caching overhead in T-Cache is negligible.

• Progress in Medical Physics
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• v.17 no.2
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• pp.83-88
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• 2006

Purpose: We Investigated to achieve high resolution magnetic resonance (MR) Imaging and spectra of human skin in vitro with using a 14.1 T MRI/MRS system, and to evaluate the hydration effect of a moisturizer by measuring the skin's water concentration. Materials and Methods: We used the Brukrer 14.1 T MRI/MRS system with a vertical standard bore that was equipped with a DMX spectrometer gradient system (200 G/cm at a maximum 40 A), RF resonators (2, 5 and 10 mm) and Para Vision software. Spin echo and fast spin echo pulse sequences were employed for obtaining the high resolution MR images. The 3D-localized point resolved spectroscopy (PRESS) method was used to acquire the MR spectra. Results: The high resolution MR images and spectra of human skin in vitro were successfully obtained on a 14.IT system. The water concentration of human skin after applying a moisturizer was higher than that before applying a moisturizer. Conclusions: The present study demonstrated that the high-resolution MR images and spectra of human skin from a high field MRS instrument could be applicable to evaluating the hydration state of the stratum corneum.

• The Journal of the Society of Korean Medicine Diagnostics
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• v.12 no.1
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• pp.42-62
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• 2008

Objectives: It is well known that some parameters of the photoplethysmogram (PPG) acquired by time domain contour analysis can be used as markers of vascular aging. But the previous studies that have been performed for frequency domain analysis of the PPG to date have provided only restrictive and fragmentary information. The aim of the present investigation was to determine whether the harmonics extracted from the PPG using a fast Fourier transformation could be used as an index of vascular aging. Methods: The PPG was measured in 600 recruited subjects for 30 second durations, To grasp the gross age-related change of the PPG waveform, we grouped subjects according to gender and age and averaged the PPG signal of one pulse cycle. To calculate the conventional indices of vascular aging, we selected the 5-6 cycles of pulse that the baseline was relatively stable and then acquired the coordinates of the inflection points. For the frequency domain analysis we performed a power spectral analysis on the PPG signals for 30 seconds using a fast Fourier transformation and dissociated the harmonic components from the PPG signals. Results: A final number of 390 subjects (174 males and 216 females) were included in the statistical analysis. The normalized power of the harmonics decreased with age and on a logarithmic scale reduction of the normalized power in the third (r=-0.492, P<0.0001), fourth (r=-0.621, P<0.0001) and fifth harmonic (r=-0.487, P<0.0001) was prominent. From a multiple linear regression analysis, Stiffness index, reflection index and corrected up-stroke time influenced the normalized power of the harmonics on a logarithmic scale. Conclusions: The normalized harmonic power decreased with age in healthy subjects and may be less error prone due to the essential attributes of frequency domain analysis. Therefore, we expect that the normalized harmonic power density can be useful as a vascular aging marker.

• Journal of Broadcast Engineering
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• v.13 no.2
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• pp.200-213
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• 2008

H.264| MPEG-4 AVC is a new video codingstandard defined by JVT (Joint Video Team) which consists of ITU-T and ISO/IEC. Many techniques are adopted fur the compression efficiency: Especially, an intra prediction in an inter frame is one example but it leads to excessive amount of encoding time due to the decision of a candidate mode and a RDcost calculation. For this reason, a fast determination of the best intra prediction mode is the main issue for saving the encoding time. In this paper, by using the result of statistical relation between intra $16{\times}16$ and $4{\times}4$ intra predictions, the number of candidate modes for $4{\times}4$ intra prediction is reduced. Firstly, utilizing motion vector obtained after inter prediction, prediction of a block mode for each macroblock is made. If an intra prediction is needed, the correlation table between $16{\times}16$ and $4{\times}4$ intra predicted modes is created using the probability during each I frame-coding process. Secondly, using this result, the candidate modes for a $4{\times}4$ intra prediction that reaches a predefined specific probability value are only considered in the same GOP For the experiments, JM11.0, the reference software of H.264|MPEG-4 AVC is used and the experimental results show that the encoding time could be reduced by 51.24% in maximum with negligible amounts of PSNR drop and bitrate increase.

• Journal of Internet Computing and Services
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• v.19 no.1
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• pp.77-86
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• 2018

For the past few years, KISTI has been servicing an online simulation execution platform, called EDISON, allowing users to conduct simulations on various scientific applications supplied by diverse computational science and engineering disciplines. Typically, these simulations accompany large-scale computation and accordingly produce a huge volume of output data. One critical issue arising when conducting those simulations on an online platform stems from the fact that a number of users simultaneously submit to the platform their simulation requests (or jobs) with the same (or almost unchanging) input parameters or files, resulting in charging a significant burden on the platform. In other words, the same computing jobs lead to duplicate consumption computing and storage resources at an undesirably fast pace. To overcome excessive resource usage by such identical simulation requests, in this paper we introduce a novel framework, called IceSheet, to efficiently manage simulation data based on execution metadata, that is, provenance. The IceSheet framework captures and stores each provenance associated with a conducted simulation. The collected provenance records are utilized for not only inspecting duplicate simulation requests but also performing search on existing simulation results via an open-source search engine, ElasticSearch. In particular, this paper elaborates on the core components in the IceSheet framework to support the search and reuse on the stored simulation results. We implemented as prototype the proposed framework using the engine in conjunction with the online simulation execution platform. Our evaluation of the framework was performed on the real simulation execution-provenance records collected on the platform. Once the prototyped IceSheet framework fully functions with the platform, users can quickly search for past parameter values entered into desired simulation software and receive existing results on the same input parameter values on the software if any. Therefore, we expect that the proposed framework contributes to eliminating duplicate resource consumption and significantly reducing execution time on the same requests as previously-executed simulations.

• Journal of the Institute of Electronics and Information Engineers
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• v.50 no.8
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• pp.253-263
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• 2013

Frequency Scanning Interferometry(FSI) system, one of the most promising optical surface measurement techniques, generally results in superior optical performance comparing with other 3-dimensional measuring methods as its hardware structure is fixed in operation and only the light frequency is scanned in a specific spectral band without vertical scanning of the target surface or the objective lens. FSI system collects a set of images of interference fringe by changing the frequency of light source. After that, it transforms intensity data of acquired image into frequency information, and calculates the height profile of target objects with the help of frequency analysis based on Fast Fourier Transform(FFT). However, it still suffers from optical noise on target surfaces and relatively long processing time due to the number of images acquired in frequency scanning phase. 1) a Polarization-based Frequency Scanning Interferometry(PFSI) is proposed for optical noise robustness. It consists of tunable laser for light source, ${\lambda}/4$ plate in front of reference mirror, ${\lambda}/4$ plate in front of target object, polarizing beam splitter, polarizer in front of image sensor, polarizer in front of the fiber coupled light source, ${\lambda}/2$ plate between PBS and polarizer of the light source. Using the proposed system, we can solve the problem of fringe image with low contrast by using polarization technique. Also, we can control light distribution of object beam and reference beam. 2) the signal processing acceleration method is proposed for PFSI, based on parallel processing architecture, which consists of parallel processing hardware and software such as Graphic Processing Unit(GPU) and Compute Unified Device Architecture(CUDA). As a result, the processing time reaches into tact time level of real-time processing. Finally, the proposed system is evaluated in terms of accuracy and processing speed through a series of experiment and the obtained results show the effectiveness of the proposed system and method.

• Investigative Magnetic Resonance Imaging
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• v.5 no.1
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• pp.57-65
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• 2001

Purpose : $T_2$-weighted half courier Echo Planar Imaging (T2HEPI) method is proposed to reduce measurement time of existing EPI by a factor of 2. In addition, high $T_2$ contrast is obtained for clinical applications. High resolution single-shot EPI images with $T_2$ contrast are obtained with $128{\times}128$ matrix size by the proposed method. Materials and methods : In order to reduce measurement time in EPI, half courier space is measured, and rest of half courier data is obtained by conjugate symmetric filling. Thus high resolution single shot EPI image with $128{\times}128$ matrix size is obtained with 64 echoes. By the arrangement of phase encoding gradients, high $T_2$ weighted images are obtained. The acquired data in k-space are shifted if there exists residual gradient field due to eddy current along phase encoding gradient, which results in a serious problem in the reconstructed image. The residual field is estimated by the correlation coefficient between the echo signal for dc and the corresponding reference data acquired during the pre-scan. Once the residual gradient field is properly estimated, it can be removed by the adjustment of initial phase encoding gradient field between $70^{\circ}$ and $180^{\circ}$ rf pulses. Results : The suggested T2EPl is implemented in a 1.0 Tela whole body MRI system. Experiments are done with the effective echo times of 72ms and 96ms with single shot acquisitions. High resolution($128{\times}128$) volunteer head images with high $T_2$ contrast are obtained in a single scan by the proposed method. Conclusion : Using the half courier technique, higher resolution EPI images are obtained with matrix size of $128{\times}128$ in a single scan. Furthermore $T_2$ contrast is controlled by the effective echo time. Since the suggested method can be implemented by software alone (pulse sequence and corresponding tuning and reconstruction algorithms) without addition of special hardware, it can be widely used in existing MRI systems.