• Title/Summary/Keyword: F2 generation

검색결과 574건 처리시간 0.025초

Characterization of Quantitative Trait Loci (QTL) for Growth using Genome Scanning in Korean Native Pig

  • Lee, H.K.;Choi, I.S.;Choi, B.H.;Kim, T.H.;Jung, I.J.
    • Reproductive and Developmental Biology
    • /
    • 제28권2호
    • /
    • pp.107-112
    • /
    • 2004
  • Molecular genetic markers were genotyped used to detect chromosomal regions which contain economically important traits such as growth traits in pigs. Three generation resource population was constructed from a cross between the Korean native boars and Landrace sows. A total of 193 F2 animals from intercross of F1 were produced. Phenotypic data on 7 traits, birth weight, body weight at 3, 5, 12, 30 weeks of age, live empty weight were collected for F2 animals. Animals including grandparents (F0), parents (F1), offspring (F2) were genotyped for 194 microsatellite markers covering from chromosome 1 to 18. Quantitative trait locus analyses were performed using interval mapping by regression under line-cross model. To characterize presence of imprinting, genetic full model in which dominance, additive and imprinting effect were included was fitted in this analysis. Significance thresholds were determined by permutation test. Using imprinting full model, four QTL with expression of imprinted effect were detected at 5% chromosome-wide significance level for growth traits on chromosome 1, 5, 7, 13, 14, and 16.

생명현상에 관한 과학적 의문 생성 과정에서 나타나는 생물학자의 두뇌 활성 양상 (The Biologists' Boon Activation Patterns during the Generation of Scientific Questions on Biological Phenomena)

  • 권용주;정진수;이준기;양일호
    • 한국과학교육학회지
    • /
    • 제27권1호
    • /
    • pp.84-92
    • /
    • 2007
  • 이 연구는 생물학자들이 생물학 현상에서 과학적 의문을 생성할 때 나타나는 두뇌의 활성을 분석하고자했다. 이를 위해서 10개의 의문 생성 과제를 개발하여 8명의 생물학자들에 투입하였고, 의문 생성 과정에서 fMRl를 통해 생물학자들의 두뇌 활성을 측정하여 분석하였다. 그 결과, 방추이랑, 전안구운동 영역, 소뇌, 좌측 전두엽, 좌우측 해마와 대상이랑, 복외측전 두피질부 등이 특징적으로 활성화되었다. 이것은 과학적 의문을 생성하는 과정에서 생물학자들의 뇌는 주어진 생물학 현상을 상세히 분석하였고, 언어적 전략을 사용하였으며, 현재의 현상과 비교하기 위해서 과거의 경험상황과 선지식 등의 장기기억을 인출하고 표상했다고 할 수 있다. 특히 복외측전 두피질부의 활성은 의문 생성 과정에서 뇌가 인지적 갈등 및 부조화 단계를 거쳤음을 보여주었다고 할 수 있다.

Bisphenol A와 butyl benzyl phthalate 동시투여가 임신랫드와 차산자에 미치는 영향 (The Reproductive Toxicity by Combined Treatment of Bisphenol A and Butyl Benzyl Phthalate During Gestation, Lactation Period in Rats)

  • 최경호;황성희;권은아;김판기
    • 한국환경보건학회지
    • /
    • 제30권2호
    • /
    • pp.71-78
    • /
    • 2004
  • This study was performed to evaluate developmental and estrogenic activity of bisphenol A (BPA) and butyl benzyl phthalate (BBP) to the second generation of Sprague-Dawley rats ingested during gestational or lactational periods. Rats were given BPA 20$\mu\textrm{g}$/kg BBP 100mg/kg of pregnancy or lactation periods. Maternal body weight and neonatal body weight were recorded. The rats were sacrificed on day 21 after birth. Reproductive organs of dam and neonate were utilized for receptor binding assay. The plasma concentrations of BPA and MBep, one of the major metabolites of BBP were analyzed with HPLC. The co-administration of BPA and BBP induced slow weight gain compared with single administration in dams. Also, such mixture induced low neonatal body weights in next generation. The dams treated with BPA and BBP during lactational periods showed significant organ weight changes in liver and spleen. The dams exposed during lactational periods showed significant organ weight changes not only in liver and spleen but also in kidney, uterus and ovary. The F1 female rats exposed during lactation periods showed significant organ weight changes in liver, spleen, ovary. The F1 male rats showed significant organ weight changes in liver, kidney, epididymis, vesicular glands, prostate. However, no clear synergistic effects of BPA and BBP were noted. There was no significantly different ER$\alpha$ expression pattern between control and treated groups. However, ER$\alpha$ expression were increased in F1 male testis and female uterus. PI male showed distinct ER$\alpha$ expression, especially in the group of lactational combined exposure. Synergistic ER$\alpha$ expression was found by combined treatment of BPA and BBP. We could not find any evidences of synergistic effects on BPA and/or BBP combined administration on dams and their fetuses, except in ER$\alpha$ expression of F1 male.

Monitoring changes in the genetic structure of Brown Tsaiya duck selected for feeding efficiency by microsatellite markers

  • Yi-Ying Chang;Hsiu-Chou Liu;Chih-Feng Chen
    • Animal Bioscience
    • /
    • 제36권3호
    • /
    • pp.417-428
    • /
    • 2023
  • Objective: Few studies have genetically monitored chickens over time, and no research has been conducted on ducks. To ensure the sustainable management of key duck breeds, we used microsatellite markers to monitor Brown Tsaiya ducks over time genetically. Methods: The second, fourth, sixth to eighth generations of the Brown Tsaiya duck selected for feeding efficiency and control lines were included in this study to investigate the genetic variations, effective population size, population structure and the differentiation between populations over time with 11 microsatellite markers derived from Brown Tsaiya duck. Results: The results showed there were a slight decrease in the genetic variations and an increase in within-population inbreeding coefficient (FIS) in both lines, but no consistent increase in FIS was observed in each line. The effective population size in the second and eighth generations was 27.2 for the selected line and 23.9 for the control line. The change in allele richness showed a downward trend over time, and the selected line was slightly lower than the control line in each generation. The number of private alleles (Np) in the selected line were higher than in the control line. Moderate differentiation was observed between the second and eighth generations in the selected line (FST = 0.0510) and the control line (FST = 0.0606). Overall, differentiation tended to increase with each generation, but genetic variation and structure did not change considerably after six generations in the two lines. Conclusion: This study provides a reference for poultry conservation and helps to implement cross-generation genetic monitoring and breeding plans in other duck breeds or lines to promote sustainable management.

연속발진 불화중수소 화학 레이저 출력특성 (Output characteristics of a continuous wave deuterium fluoride chemical laser)

  • 이정환;박병서;김재기
    • 한국광학회지
    • /
    • 제13권1호
    • /
    • pp.65-69
    • /
    • 2002
  • 불소원자(F)와 D$_2$ 기체 발열반응에 의해 레이저 이득매질인 DF 여기분자를 생성시키는 구조의 연속발진형 불화중수소 (DF)화학 레이저를 설계, 제작하고 발진 실험을 수행하였다. 불소원자는 F$_2$ 기체와 H$_2$ 기체를 연소시켜 생성시키고, 불소원자를 초음속 노즐을 통과시킨 직후에 D$_2$ 기체를 분사하여 형성된 DF 여기분자 초음속 흐름을 활성 매질로 사용하여 레이저를 발진시켰다. 본 연구에서 얻은 레이저 발진 출력은 101W이며, 최적의 유량조건에서 얻은 화학 효율은 5.12%, 비출력은 96.5 J/g이다.

기계학습 기반 개체명 인식을 위한 사전 자질 생성 (Feature Generation of Dictionary for Named-Entity Recognition based on Machine Learning)

  • 김재훈;김형철;최윤수
    • 정보관리연구
    • /
    • 제41권2호
    • /
    • pp.31-46
    • /
    • 2010
  • 오늘날 정보 추출의 한 단계로서 개체명 인식은 정보검색 분야 뿐 아니라 질의응답과 요약 분야에서 매우 유용하게 사용되고 있다. 개체명은 일반 단어와 달리 다양한 문서에서 꾸준히 생성되고 변화되고 있다. 이와 같은 개체명의 특성 때문에 여러 응용 시스템에서 미등록어 문제가 야기된다. 본 논문에서는 이런 미등록어 문제를 해결하기 위해 기계학습 기반 개체명 인식 시스템을 위한 새로운 자질 생성 방법을 제안한다. 일반적으로 기계학습 기반 개체명 인식 시스템은 단어 단위의 자질을 사용하므로 구절 단위의 개체명을 그대로 자질로 사용할 수 없다. 이 문제를 해결하기 위해 본 논문에서는 새로운 구절 단위의 정보를 단어 단위의 자질로 변환하는 자질 생성 방법을 제안하였다. 이 방법으로 개체명 사전과 WordNet을 개체명 인식의 자질로 사용할 수 있었다. 그 결과 영어 개체명 시스템은 F1 점수의 약 6%가 향상되었고 오류의 약 38%가 줄어들었다.

유유아(乳幼兒) 및 성장기 아동을 위한 영양식품 개발에 관한 연구 -흰쥐 성장에 미치는 영향- (The Protein rich Food Mixtures for Korean Infants)

  • 호진희;김숙희
    • Journal of Nutrition and Health
    • /
    • 제3권2호
    • /
    • pp.95-99
    • /
    • 1970
  • Korea is one of the typical rice eating countries where availability of animal protein is limited even for the growing generation. Nutritive food products for infants and children are not available commercially in large scale at the present time, although a limited amount of expensive milk products are produced. The present study deals with a pioneering attempt on a new food mixture to meet this demand. Several food mixtures, possibly produced in the country, consisting of rice, soybean, FPC, vitamin, minerals and other food additives are developed in this work Sixty female and male rats aged $30{\sim}40$ days were divided into five groups, twelve rats each. The rats had been maintained with the six different diets, as follow. Formulation of proposed infant food mixturesComposition F-R-1 F-S-2 F-F-3 F-P-4 S Rice 100% 40% 37% 46% 70% Sugar - 12 13 10 70 Casein - - - - 20 Bean - 40 37 24 - Yeast - 3 2 3 - Mineral Vitamain - 2 4 2 4.3 F.P.C - 3 4 7 - Fat - - 4 8 4 Cod liver Oil - - - - 3 The findings of this study presented in FER, PER, final organ weights, body weights growth, percentage of nitrogen retention in the body. F-P-4 group tended to remain the heaviest and F-R-1 the lightest in the body weight among three groups throughout the experimental period. In terms of FER (Feed Efficiency Ratio) and PER (Prortein E. R.) value, F-P-4 group kept the highest record throughout. F-P-4 group showed the highest value of nitrogen retention in the body. In comparision between F-P-4 groups and casein 20% group (standard) in all respects of this experiment, F-P-4 group which is the most superior among experimental group, revealed statisfically no significant inferior than that of standard group. This fact could be interpreted that most limiting a. a., methionine in the soy protein produced little inferiority of the experimental groups in the study.

  • PDF

누에 육종에 있어서 잡종강세, 선발지수, 유전진전, 선발효율에 관한 연구 (Studies on Heterosis Selective Index, Genetic Advance and Selective Efficiency for some Characters in Silkworm Breeding)

  • 정원복
    • 한국잠사곤충학회지
    • /
    • 제32권1호
    • /
    • pp.8-16
    • /
    • 1990
  • 누에 7개 품종을 이면교잡하여 얻은 F$_1$, 세대에 대한 잡종강세, 선발지수 그리고 유전적 진전 등을 분석한 결과는 다음과 같다. 잡종강세는 F$_1$세대에서 5령경과, 견층연감율의 자웅이 부의 방향을 나타냈고 견층비율을 제외한 전 형질이 20.90-37.60%로 정의 높은 강세율을 나타내었다. F$_2$에서는 견층비율, 견층연감율의 자웅이 부로, 그 외의 전 형질이 정의 강세율을 나타내었다. 선발지수는 선발의 최종대상형질을 견사량으로 하였을 때 F$_1$, F$_2$세대 모두 단일형질에서 단견중이 높았다. 선발대상형질을 5령경과, 단견중 견층중, fibroin량 등의 4개 형질로 하여 2, 3, 4형질을 조합하였을 때, 5령 경과와 단견중의 조합에서 선발가중치가 가장 크게 나타났다. 유전진전은 F$_1$, F$_2$세대에서 한일형질에서는 모두 견층중이 가장 높았고, 각 형질간의 조합에서는 전 형질을 조합하였을 때가 가장 높았다. 관계효율도 전 형질을 조합하였을 때가 가장 높았다.

  • PDF

Development of high yield rice of long grain type adaptable to South-East Asia tropical region

  • Cho, YC;Baek, MK;Park, HS;Nam, JK;Jeong, JM;Kim, WJ;Shin, WC;Song, YC;Cho, JH;Lee, JY;Kim, CS;Park, HG;Kim, BK
    • 한국작물학회:학술대회논문집
    • /
    • 한국작물학회 2017년도 9th Asian Crop Science Association conference
    • /
    • pp.339-339
    • /
    • 2017
  • The long grain rice varieties adaptable to South-east Asia tropical regions were tried to develop in Cambodian Agriculture Research and Development Institute (CARDI), Cambodia. The final goal is to develop rice varieties which can culture in diverse environmental conditions of tropical regions of South-east Asia under climate change. We collected and evaluated for agronomic traits of 131 rice germplasm from Cambodia, China, India, Indonesia, Myanmar, Philippines and Vietnam in CARDI. We selected core germplasm including leading varieties of target countries and made 813 F1 cross combinations between leading varieties of each country and promising germplasm of high yield potential, resistance to biotic/abiotic stresses, aromatic rice, and so on. Out of 607 F1s evaluated to heading date, plant type, agronomic traits, and grain type, 106 F1s selected and advanced to F2 populations. 106 F2 populations were evaluated to major agronomic traits, grain type and yield-component traits, and selected 2,560 plants in 62 F2 populations. During six seasons in 2014~2016, the lines of F3 subsequent-generation were cultured a total of 6,256 lines. In yield trial for promising lines in F5 generation, the growth duration from sowing to harvesting was 97~114 days. These lines were 88~129 in number of grain per panicle, an average of 84.6% in the range of 79.3~91.9% in the percentage of ripened grain and 17.5~22.8g in 1000-brown rice weight. The rough rice yields were in the range of 4.33~6.06 ton/ha with an average of 5.23 ton/ha. The yield was increased to 5~47% than Chulsa and 12~41% than IR66. Five lines, KR54-28-1, KR55-14-2, KR57-5-2, KR67-57-2 and KR128-19-1 were 5.33~6.06 ton/ha in rough rice yield. These high yield potential lines would be evaluated to adaptability in Cambodia, Laos, Myanmar and Vietnam during 2017.

  • PDF

Development of high yield rice of long grain type adaptable to South-East Asia tropical region

  • Cho, YC;Baek, MK;Park, HS;Nam, JK;Jeong, JM;Kim, WJ;Shin, WC;Song, YC;Cho, JH;Lee, JY;Kim, CS;Park, HG;Kim, BK
    • 한국작물학회:학술대회논문집
    • /
    • 한국작물학회 2017년도 9th Asian Crop Science Association conference
    • /
    • pp.155-155
    • /
    • 2017
  • The long grain rice varieties adaptable to South-east Asia tropical regions were tried to develop in Cambodian Agriculture Research and Development Institute (CARDI), Cambodia. The final goal is to develop rice varieties which can culture in diverse environmental conditions of tropical regions of South-east Asia under climate change. We collected and evaluated for agronomic traits of 131 rice germplasm from Cambodia, China, India, Indonesia, Myanmar, Philippines and Vietnam in CARDI. We selected core germplasm including leading varieties of target countries and made 813 F1 cross combinations between leading varieties of each country and promising germplasm of high yield potential, resistance to biotic/abiotic stresses, aromatic rice, and so on. Out of 607 F1s evaluated to heading date, plant type, agronomic traits, and grain type, 106 F1s selected and advanced to F2 populations. 106 F2 populations were evaluated to major agronomic traits, grain type and yield-component traits, and selected 2,560 plants in 62 F2 populations. During six seasons in 2014~2016, the lines of F3 subsequent-generation were cultured a total of 6,256 lines. In yield trial for promising lines in F5 generation, the growth duration from sowing to harvesting was 97~114 days. These lines were 88~129 in number of grain per panicle, an average of 84.6% in the range of 79.3~91.9% in the percentage of ripened grain and 17.5~22.8g in 1000-brown rice weight. The rough rice yields were in the range of 4.33~6.06 ton/ha with an average of 5.23 ton/ha. The yield was increased to 5~47% than Chulsa and 12~41% than IR66. Five lines, KR54-28-1, KR55-14-2, KR57-5-2, KR67-57-2 and KR128-19-1 were 5.33~6.06 ton/ha in rough rice yield. These high yield potential lines would be evaluated to adaptability in Cambodia, Laos, Myanmar and Vietnam during 2017.

  • PDF