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Characterization of Quantitative Trait Loci (QTL) for Growth using Genome Scanning in Korean Native Pig  

Lee, H.K. (Genomic Informatics Center, Hankyong National University)
Choi, I.S. (Department of Bionolgy Genomic Engineering, Hankyong National University)
Choi, B.H. (Genomic Informatics Center, Hankyong National University)
Kim, T.H. (Genomic Informatics Center, Hankyong National University)
Jung, I.J. (Genomic Informatics Center, Hankyong National University)
Publication Information
Reproductive and Developmental Biology / v.28, no.2, 2004 , pp. 107-112 More about this Journal
Abstract
Molecular genetic markers were genotyped used to detect chromosomal regions which contain economically important traits such as growth traits in pigs. Three generation resource population was constructed from a cross between the Korean native boars and Landrace sows. A total of 193 F2 animals from intercross of F1 were produced. Phenotypic data on 7 traits, birth weight, body weight at 3, 5, 12, 30 weeks of age, live empty weight were collected for F2 animals. Animals including grandparents (F0), parents (F1), offspring (F2) were genotyped for 194 microsatellite markers covering from chromosome 1 to 18. Quantitative trait locus analyses were performed using interval mapping by regression under line-cross model. To characterize presence of imprinting, genetic full model in which dominance, additive and imprinting effect were included was fitted in this analysis. Significance thresholds were determined by permutation test. Using imprinting full model, four QTL with expression of imprinted effect were detected at 5% chromosome-wide significance level for growth traits on chromosome 1, 5, 7, 13, 14, and 16.
Keywords
Microsatellite; QTL mapping; Imprinting effect; Korean Native pig; Genome scanning;
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