• 제목/요약/키워드: F.E.M analysis

검색결과 568건 처리시간 0.024초

Cryptosporidium spp., Giardia intestinalis, and Enterocytozoon bieneusi in Captive Non-Human Primates in Qinling Mountains

  • Du, Shuai-Zhi;Zhao, Guang-Hui;Shao, Jun-Feng;Fang, Yan-Qin;Tian, Ge-Ru;Zhang, Long-Xian;Wang, Rong-Jun;Wang, Hai-Yan;Qi, Meng;Yu, San-Ke
    • Parasites, Hosts and Diseases
    • /
    • 제53권4호
    • /
    • pp.395-402
    • /
    • 2015
  • Non-human primates (NHPs) are confirmed as reservoirs of Cryptosporidium spp., Giardia intestinalis, and Enterocytozoon bieneusi. In this study, 197 fresh fecal samples from 8 NHP species in Qinling Mountains, northwestern China, were collected and examined using multilocus sequence typing (MLST) method. The results showed that 35 (17.8%) samples were positive for tested parasites, including Cryptosporidium spp. (3.0%), G. intestinalis (2.0%), and E. bieneusi (12.7%). Cryptosporidium spp. were detected in 6 fecal samples of Macaca mulatta, and were identified as C. parvum (n=1) and C. andersoni (n=5). Subtyping analysis showed Cryptosporidium spp. belonged to the C. andersoni MLST subtype (A4, A4, A4, and A1) and C. parvum 60 kDa glycoprotein (gp60) subtype IId A15G2R1. G. intestinalis assemblage E was detected in 3 M. mulatta and 1 Saimiri sciureus. Intra-variations were observed at the triose phosphate isomerase (tpi), beta giardin (bg), and glutamate dehydrogenase (gdh) loci, with 3, 1, and 2 new subtypes found in respective locus. E. bieneusi was found in Cercopithecus neglectus (25.0%), Papio hamadrayas (16.7%), M. mulatta (16.3%), S. sciureus (10%), and Rhinopithecus roxellana (9.5%), with 5 ribosomal internal transcribed spacer (ITS) genotypes: 2 known genotypes (D and BEB6) and 3 novel genotypes (MH, XH, and BSH). These findings indicated the presence of zoonotic potential of Cryptosporidium spp. and E. bieneusi in NHPs in Qinling Mountains. This is the first report of C. andersoni in NHPs. The present study provided basic information for control of cryptosporidiosis, giardiasis, and microsporidiosis in human and animals in this area.

수치해석법에 의한 비대칭 변단면 기둥의 탄성 임계하중 (Elastic Critical Load of Non-symmetrically Tapered Columns by Numerical Method)

  • 신세욱;김선혜;이수곤
    • 한국전산구조공학회:학술대회논문집
    • /
    • 한국전산구조공학회 1999년도 봄 학술발표회 논문집
    • /
    • pp.11-18
    • /
    • 1999
  • For the proper design of a slender compression member, the exact determination of the elastic critical load is crucial, In the cases of non-prismatic compression members, the determinations of the elastic critical load cannot be usually expressed in closed forms. h this paper, the non-symmetrically tapered compression members with arbitrary boundary conditions me analysed by using the finite element method to determine the elastic critical load. The main parameters considered in the numerical analysis are the In Parameter, $\alpha$ and the sectional property parameter, m. To generaliza the unmerical analysis, of the computed results for each sectional parameter, m are presented in algebraic equations, which agrees fairy well with those by F.E.M in most cases.

  • PDF

단순지지 변단면 압축재의 임계하중 (Elastic Critical Laod of Tapered Columns)

  • 홍종국;김순철;이수곤
    • 한국전산구조공학회:학술대회논문집
    • /
    • 한국전산구조공학회 1999년도 봄 학술발표회 논문집
    • /
    • pp.252-259
    • /
    • 1999
  • One of the most important factors for a proper design of a slender compression member may be the exact determination of the elastic critical load of that member. In the cases of non-prismatic compression member, however, there are times when the exact critical load becomes impossible to determinate if one relies on the neutral equilibrium method or energy principle. Here in this paper, the approximate critical loads of symmetrically or non-symmetrically tapered members are computed by finite element method. The two parameters considered in this numerical analysis are the taper parameter, $\alpha$ and the sectional property parameters, m. The computed results for each sectional property parameter, m are presented in an algebraic equation which agrees with those by F.E.M The algebraic equation can be easily used by structural engineers, who are engaged in structural analysis and design of non-prismatic compression member.

  • PDF

광촉매 TiO2의 황산용액에서의 양극산화전압과 도핑이 광촉매 활성에 미치는 영향 (Effects of Anodic Voltages of Photcatalytic TiO2 and Doping in H2SO4 Solutions on the Photocatalytic Activity)

  • 이승현;오한준;지충수
    • 한국재료학회지
    • /
    • 제22권8호
    • /
    • pp.439-444
    • /
    • 2012
  • To compare the photocatalytic performances of titania for purification of waste water according to applied voltages and doping, $TiO_2$ films were prepared in a 1.0 M $H_2SO_4$ solution containing $NH_4F$ at different anodic voltages. Chemical bonding states of F-N-codoped $TiO_2$ were analyzed using surface X-ray photoelectron spectroscopy (XPS). The photocatalytic activity of the co-doped $TiO_2$ films was analyzed by the degradation of aniline blue solution. Nanotubes were formed with thicknesses of 200-300 nm for the films anodized at 30 V, but porous morphology was generated with pores of 1-2 ${\mu}m$ for the $TiO_2$ anodized at 180 V. The phenomenon of spark discharge was initiated at about 98 V due to the breakdown of the oxide films in both solutions. XPS analysis revealed the spectra of F1s at 684.3 eV and N1s at 399.8 eV for the $TiO_2$ anodized in the $H_2SO_4-NH_4F$ solution at 180 V, suggesting the incorporation of F and N species during anodization. Dye removal rates for the pure $TiO_2$ anodized at 30 V and 180 V were found to be 14.0% and 38.9%, respectively, in the photocatalytic degradation test of the aniline blue solution for 200 min irradiation; the rates for the F-N-codoped $TiO_2$ anodized at 30 V and 180 V were found to be 21.2% and 65.6%, respectively. From the results of diffuse reflectance absorption spectroscopy (DRS), it was found that the absorption edge of the F-N-codoped $TiO_2$ films shifted toward the visible light region up to 412 nm, indicating that the photocatalytic activity of $TiO_2$ is improved by appropriate doping of F and N by the addition of $NH_4F$.

Anti-angiogenic, Anti-cell Adhesion Switch from Halophilic Enterobacteria

  • Lim, Jong Kwon;Seo, Hyo Jin;Kim, Eun Ok;Meydani, Mohsen;Kim, Jong Deog
    • 한국해양바이오학회지
    • /
    • 제1권3호
    • /
    • pp.156-162
    • /
    • 2006
  • The halophilic enterobacteria, Enterobacteria cancerogenus, was isolated from the intestines of the fusiform fish (Trachurus japonicus) to yield a protein-like material termed PLM-f74. PLM-f74 was characterized by strong inhibition ratios to angiogenesis (82.8% at the concentration of $18.5{\mu}g/mL$) and elevated antioxidative capacities with low toxicity. The PLM-f74 is a glycoprotein comprised of saccharides and amino acids. PLM-f74 inhibited non-activated U937 monocytic cell adhesion to HUVECs activated with IL-$1{\beta}$ by 78.0%, and the adherence of U937 cells treated with the PLM-f74 and stimulated with IL-$1{\beta}$ to unstimulated HUVECs decreased by 102%. When both cell types were pretreated with PLM-f74, the adhesion of U937 cells to IL-$1{\beta}$ stimulated HUVECs was completely suppressed by 121% at a concentration of 18.5 ug/mL. PLM-f74 blocked signal pathways from VEGFR2, PI3K, ${\beta}$-catenin and VE-cadherin to NF-kB based on western bolt analysis. And also inhibited IL-1-stimulated HUVEC expression of the adhesion molecules, ICAM-1 by 40%, VCAM-1 by 60%, and E-selectin by 70% at the same concentration noted above. New anti-angiogenic and anti-cell adhesion materials showing elevated antioxidative capacities and non-toxicity may be expected from these results.

  • PDF

Salmonella typhi KNIH100으로부터 aroD 유전자의 클로닝과 염기서열 분석 (Cloning and Nucleotide Sequence Analysis of the aroD Gene from Salmonella typhi KNIHI100)

  • 길영식;전형규;신희정;김영창
    • 미생물학회지
    • /
    • 제36권3호
    • /
    • pp.187-191
    • /
    • 2000
  • 장티푸스는 Salmonella typhi 에 의해 유발되는 장감염성 질환으로 사람과 동물에 공통되는 질병이다. 본 연구에서는 기 보고된Salmonella typhi KNH100의 염색체 DNA로부 터 방향족 아미노산의 생합성에 관여하는 효소인 3-dehydroquinate hydratase(3- dehydroquinate)를 암호화하는 aroD 유전자를 포함하는 약 3.2 kb의 Sal I 절편을 pSAL62 이라 명명하였다. 클로닝된 재조합 plasmid인 pSAL61에는 ATG 개시코돈과 TGA 종결코돈 을 포함하는 759 염기로 구성된 aroD 유전자가 위치하고 있었다. 또한 S. typhi Ty2, Shigella dysenteriae, 그리고 Escherichia coli 등 다른 장내 세균의 aroD 유전자와 상동성을 비교하여 본 결과 각각 90%, 72.7% 그리고 73%의 상동성을 나타내었다.

  • PDF

초크랄스키 방법으로 성장한 CaF2 단결정 분석 (Analysis of calcium fluoride single crystal grown by the czochralski method)

  • 이하린;나준혁;박미선;장연숙;정해균;김두근;이원재
    • 한국결정성장학회지
    • /
    • 제32권6호
    • /
    • pp.219-224
    • /
    • 2022
  • 광학 윈도우, 프리즘, 렌즈 등에 사용되는 CaF2 단결정은 3개의 부격자를 가진 face-centered cubic(FCC) 구조를 가지고 있으며 밴드갭(12 eV)이 크고 넓은 파장영역에서 투과율이 우수하고 굴절률이 낮다는 특징이 있다. CaF2 단결정 성장은 대표적으로 높은 생산효율과 큰 결정을 만들 수 있는 초크랄스키(Czochralski) 방법으로 생산되고 있다. 이 연구에서는 초크랄스키 방법으로 성장한 일본의 Nikon 사와 미국의 M TI 사 (100)면, (111)면의 CaF2 단결정 상용화 웨이퍼의 결정성과 결함밀도를 분석하기 위해 X선 회절(XRD), XRC(X-ray rocking curve) 측정 및 Chemical Etching을 수행하였고 푸리에 변환 적외선 분광법(FT-IR)과 UV-VIS-NIS을 이용하여 CaF2 결정의 광학적 특성을 분석하였다. 다양한 분석 결과를 통해 CaF2 단결정의 다양한 분야에서의 응용가능성을 체계적으로 살펴보았다.

폴리머 압출 제품의 형상예측 및 실험결과 비교분석 (Shape prediction of polymer extrusion product and Comparative Analysis of experimental results)

  • 김수현;나상화;유철종
    • 한국소성가공학회:학술대회논문집
    • /
    • 한국소성가공학회 2008년도 추계학술대회 논문집
    • /
    • pp.110-113
    • /
    • 2008
  • This study was performed to predict the shape of polymer extrusion product and to find the cause of defective products Experiments was performed to extrude the complex profile shape using PC/ABS composite resin with new profile die and cooling die. A finite element analysis for the Polymer Extrusion process considering the heat transfer and thermal deformation was also performed, and the result was compared with the experimental data. It is found that the predicted profile shape in F. E. M was similar to the experimental result and the thickness of extruded product was thin when the velocity of profile die outlet was slow than the velocity of production (2m/min).

  • PDF

생체역학의 유한요소법 응용 (Analysis of Bony Structures by F.E.M.)

  • 우광성
    • 전산구조공학
    • /
    • 제6권4호
    • /
    • pp.5-9
    • /
    • 1993
  • 본 논문에서는 생체역학 중 주로 뼈 구조에 유한요소법이 어떻게 사용되고 있는지에 대해 주로 정형외과에서 중요시되는 대퇴부, 요추 등의 예제를 통해 어떻게 모델링되고 있으냐와 유한요소법의 응용분야에 대해 간략히 설명하였다. 물론, 생체역학이라고 하면 허파, 심장 등을 포함하는 순환기, 혈관, 치아 등등 여러 분야를 일컫는 용어로 그 연구분야에 구조공학자의 관심이 필요로 함을 강조하고 싶다. 아울러 유한요소해석 결과에 대해서는 본 논문에서는 언급하지 않았지만 비교적 실험치에 비해 근사함을 여러 문헌을 통해 알 수 있다. 국내에서는 아직도 이 분야에 대한 연구가 매우 미진한 상태이므로 향후 이에 대한 연구가 수행되어야 할 것으로 사료된다.

  • PDF

동특성변화에 따른 구조물의 변경된 설계파라미터 예측 (Prediction of Structural Modified Design Parameter due to the Change of Dynamic Characteristic)

  • 이정윤
    • 한국공작기계학회:학술대회논문집
    • /
    • 한국공작기계학회 2004년도 춘계학술대회 논문집
    • /
    • pp.191-196
    • /
    • 2004
  • This study proposed the analysis of mass position detection and modified stiffness due to the change of the mass and stiffness of structure by using the original and modified dynamic characteristics. The method is applied to examples of a cantilever and 3 degree of freedom by modifying the mass. The predicted detection of mass positions and magnitudes are in good agrement with these from the structural reanalysis using the modified mass.

  • PDF