• Journal of Veterinary Clinics
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• v.16 no.1
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• pp.203-209
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• 1999

A 4-year-old female Shih-tzu with severe episcleral congestion and buphthalmos in left eye was referred to the Veterinary Teaching Hospital, Chonnam National University in October 1998. During two months in local veterinary clinics, the dog had been treated unsuccessfully with tarsorrhaphy and antibiotics. By history taking, cause of the glaucoma was ascertained as accidental nonpenetrated cornea trauma by owner, Ophthalmic examination revealed that the left eye was buphthalmic with severe episcleral congestion, pain and fever. The direct pupillary light response could not be evaluated in the left eye, but right eye had normal reaction. The intraocular pressure was 4.5 mmHg in the right eye and 33 mmHg in the left eye, as measured with a Schiotz tonometer, Ultrasonographic finding revealed hyperechoic vitrous body and central echofree material. The Schirmer tear test showed 20 mm in the left eye and 8 mm in the right eye. The hematologic examination revealed monocytosis. The initial medical treatment was admitted, but there was no response. Transpalpebral enucleation in the left eye under inhalation anesthesia with enflurane 1.2 vol% in oxygen was performed. The day after operation the left eye ravealed no exudate, and pain, and the systemic vital signs were normal. The prognosis is excellent.

• Clinical and Experimental Pediatrics
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• v.56 no.6
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• pp.254-259
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• 2013

Purpose: Retinoblastoma (RB) is the most common primary malignant intraocular tumor in children. Although systemic chemotherapy has been the primary treatment, intra-arterial chemotherapy (IAC) represents a new treatment option. Here, we performed alternate systemic chemotherapy and IAC and retrospectively reviewed the efficacy and safety of this approach. Methods: Patients diagnosed with intraocular RB between January 2000 and December 2011 at Severance Children's Hospital, Yonsei University, were reviewed. Before February 2010, the primary treatment for RB was chemotherapy (non-IAC/CTX). Since February 2010, the primary treatment for RB has been IAC (IAC/CTX). External beam radiotherapy or high-dose chemotherapy were used as "last resort" treatments just prior to enucleation at the time of progression or recurrence during primary treatment. Enucleation-free survival (EFS) and progression-free survival were assessed. Results: We examined 19 patients (median age, 11.9 months; range, 1.4 to 75.6 months) with a sum of 25 eyes, of which, 60.0% were at advanced Reese Ellsworth (RE) stages. The enucleation rate was 33.3% at early RE stages and 81.8% at advanced RE stages (P=0.028). At 36 months, EFS was significantly higher in the IAC/CTX group than in the non-IAC/CTX group (100% vs. 40.0%, P=0.016). All 5 patients treated with IAC achieved eye preservation, although most patients were at advanced RE stages (IV-V). Conclusion: Despite the limitation of a small sample size, our work shows that an alternative combined approach using IAC and CTX may be safe and effective for eye preservation in advanced RB.

• Parasites, Hosts and Diseases
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• v.49 no.2
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• pp.173-175
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• 2011

Ophthalmomyiasis rarely occurs worldwide, and has not been reported in Korea. We present here a case of ophthalmomyiasis caused by Phormia sp. fly larva in an enucleated eye of a patient. In June 2010, a 50-year-old man was admitted to Dankook University Hospital for surgical excision of a malignant melanoma located in the right auricular area. He had a clinical history of enucleation of his right eye due to squamous cell carcinoma 5 years ago. During hospitalization, foreign body sensation developed in his right eye, and close examination revealed a fly larva inside the eye, which was evacuated. The larva was proved to be Phormia sp. based on the morphology of the posterior spiracle. Subsequently, no larva was found, and the postoperative course was uneventful without any complaints of further myiasis. This is the first case of ophthalmomyiasis among the literature in Korea, and also the first myiasis case caused by Phormia sp. in Korea.

• Journal of Veterinary Clinics
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• v.34 no.2
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• pp.123-125
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• 2017

An eight-year-old Shih-Tzu dog was referred to Kyungpook National University Veterinary Medical Teaching Hospital because of severe glaucoma and exophthalmos. The symptoms included severe buphthalmos, conjunctival hyperemia, focal dried cornea and discomfort in the affected eye. Although enucleation was considered as a potential intervention measure in light of the severity of symptoms, it was possible to save the globe and relieve symptoms through evisceration, intraocular prosthesis implantation, and lateral canthoplasty. Our experience with this case suggests that symptomatic salvage therapy, rather than enucleation, is an appropriate approach for resolution of exopthalmos and other complications associated with glaucoma surgery.

• Archives of Plastic Surgery
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• v.48 no.1
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• pp.80-83
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• 2021

Eye socket contracture is a well-known late complication of enucleation surgery, and the additional insult of radiotherapy at an early age causes even further fibrosis and scarring of the socket. Management of the contracted socket is challenging, and several methods have been proposed. We report a case of eye socket contracture after enucleation and radiotherapy in which multiple reconstructive procedures failed. The recurrent contracture caused difficulty in housing and retaining the eye prosthesis. We reconstructed the lower eyelid with a facial artery myomucosal flap and nasolabial flap, and the upper eyelid with a Fricke flap following reconstruction of the orbital rims (supraorbital and infraorbital rims with a calvarial bone graft, and further augmentation of the infraorbital rim with a rib bone graft). Cosmesis post-reconstruction was acceptable and the prosthesis was retained very well.

• Animal cells and systems
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• v.2 no.3
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• pp.389-393
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• 1998

We localized a calcium-binding protein, calretinin, in the superior colliculus of the mouse and studied the distribution and effect of eye enucleation on the distribution of this protein. Calretinin was localized with immunocyto-chemistry. A dense plexus of anti-calretinin-labeled fibers was found within the superficial layers. The highest density was found in the deep superficial gray layer. Monocular enucleation produced an almost complete reduction of calretinin-immunoreactive fibers in the superficial layers of the superior colliculus contralateral to the enucleation. Furthermore, many calretinin-labeled cells appeared in the contralateral superior colliculus. These newly appeared neurons had small oval or round cell bodies. The results demonstrate that calretinin identify unique neuronal sublaminar organizations in the superior colliculus of the mouse. They also suggest that the retinal projection may control in part the content of calretinin in some neurons in the superficial layers of the mouse superior colliculus.

• Journal of Veterinary Clinics
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• v.32 no.2
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• pp.205-208
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• 2015

A 6-year old, neutered male, Maltese dog was presented in Veterinary Medical Teaching Hospital, Seoul National University. As hyphema and aqueous flare in the right eye were found, medical treatment for uveitis was started. Four months later, anterior displacement of dorsotemporal iris was observed. A mass originating from ciliary body of the right eye was revealed by ocular sonography. There was no evidence of metastasis on thoracic and abdominal radiographic imaging. Enucleation was performed on the right eye due to the enlargement of the mass and deteriorating uveitis. On histopathological evaluation, anterior uveal melanocytoma with chronic hemorrhage was confirmed. This case suggests adequate removal of intraocular neoplasm by enucleation can be curative in case of continuous hemorrhage or inflammation in the eye that cannot be controlled by non-surgical medications.

• Journal of Veterinary Clinics
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• v.39 no.6
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• pp.411-416
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• 2022

A 2.2 kg adult female Amur leopard cat (Prionailurus bengalensis) injured in a road accident was rescued. Severe abrasions on the left chin were washed daily with an antiseptic and silver sulfadiazine ointment was applied. Corneal edema of the oculus sinister (OS) was treated with ofloxacin and 5% sodium chloride eye drops. The skin wounds gradually improved, but the eye condition did not improve and the lens was also found to be detached. In addition, on the 6th day of hospitalization, melena was observed. On radiographic examination, foreign bodies in the stomach and a fracture of the sternum were confirmed. Subsequently, endoscopic removal of foreign bodies and enucleation of the OS using an electrothermal vessel sealer were performed sequentially over several days. However, corrective surgery of the fractured sternum was not carried out because a natural union of the fracture had occurred, which was found to be fairly stable. The patient completely recovered on the 83rd day and was successfully released into the wild on the 97th day, after two weeks of adaptation training in a natural environment. This report describes the rehabilitation of a wild Amur leopard cat injured in a road accident through a series of diagnostic and treatment steps until its eventual return to the wild and highlights some improvements needed in the process.

• Journal of Veterinary Clinics
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• v.32 no.1
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• pp.123-126
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• 2015

A 14-year-old, male Shih-tzu was presented with glaucoma in the left eye. Menace response was negative in the left eye. On ophthalmic examination, exotropia, buphthalmos, bulging of upper lateral globe and episcleral injection was detected in the left eye. Also, there was corneal edema, corneal pigmentation and hyphema in the left eye. The pupil was difficult to observe due to corneal lesions in the left eye. On ultrasonographic examination, an amorphous large mass protruding from the region of the optic disc into the vitreous was observed in the left eye. Enucleation was performed in the left eye. Histologically, the left intraocular mass was diagnosed as glioma. Immunohistochemically, the neoplastic cells were positive to glial fibrillary acidic protein.

• Archives of Craniofacial Surgery
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• v.25 no.1
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• pp.31-37
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• 2024

Orbital floor fractures are commonly encountered, but the dislocation of the eyeball into the maxillary sinus is relatively rare. When it does occur, globe dislocation can have serious consequences, including vision loss, enucleation, and orbito-ocular deformity. Immediate surgical intervention is typically attempted when possible. However, severe comorbidities and poor general health can delay necessary surgery. In this report, we present the surgical outcomes of a 70-year-old woman who received delayed treatment for traumatic eyeball dislocation into the maxillary sinus due to a subarachnoid hemorrhage and hemopneumothorax. Additionally, we propose a treatment algorithm based on our clinical experience and a review of the literature.