• 제목/요약/키워드: Extrarenal Wilms' tumor

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폐와 골 전이를 동반한 후복막강 내 신외 윌름 종양 1례 (A Case of Retroperitoneal Extrarenal Wilms' Tumor with Metastasis to Lung and Bone)

  • 정재헌;한원철;최두영
    • Clinical and Experimental Pediatrics
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    • 제48권1호
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    • pp.112-115
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    • 2005
  • 저자들은 8세 남아에서 교통사고 후 우연히 발견된 혈흉과 복부 종물의 진단 과정에서 확진된 폐 및 골 전이를 동반한 후복강 내 신외 윌름 종양 1례를 경험하였기에 문헌 고찰과 함께 보고 하고자 한다.

폐로 전이한 Wilms 종양의 세침흡인 세포학적 소견 - 2예 보고 - (Fine Needle Aspiration Cytology of Metastatic Wilms' Tumor in the Lung - Report of Two Cases -)

  • 김완섭;김남훈;고영혜;박문향;이중달
    • 대한세포병리학회지
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    • 제7권2호
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    • pp.218-224
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    • 1996
  • We describe two cases of metastatic Wilms' tumor in the lung with emphasis on the cytologic features of specimens obtained by needle aspiration. One of them was extrarenal Wilms' tumor. The findings were correlated with the histopathologic features of the primary lesion. Cellular components in the fine needle aspiration cytology (FNAC) slides included blastemal, epithelial, stromal and inflammatory cells with immature tubular differentiation and rosette formation. Recognition of these cellular components in FNAC smears help in establishing FNAC diagnosis of Wilms' tumor. The blastemal cells were represented by small to medium sized cells with scanty cytoplasm having ill-defined borders and round to slightly oval nuclei with evenly dispersed chromatin and small marginated nucleoli. They were seen in our two cases. The differential diagnosis includes neuroblastoma, malignant lymphoma, malignant rhabdoid tumor, clear cell sarcoma, Ewing's sarcoma and embryonal rhabdomyosarcoma. In conclusion, making a definite cytologic diagnosis of metastatic Wilms' tumor may be possible by light and electron microscopy and immunohistochemical staining. The above findings may contribute to the diagnosis of FNAC of metastatic Wilms' tumor.

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신장외 악성 횡문양 종양 - 1예 보고 - (Extrarenal Malignant Rhabdoid Tumor - A Case Report -)

  • 이상용;김대철;나서희;홍숙희;강태훈;이영호;남경진;정진숙
    • 대한세포병리학회지
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    • 제7권1호
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    • pp.69-74
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    • 1996
  • Malignant rhabdold tumor is a distinct renal tumor in the pediatric age group. It was originally described as a rhabdomyosarcomatold variant of Wilms' tumor. However, subsequent studies fatted to confirm myogenous differentiation, so it is now considered to be a distinct and unique type of highly malignant tumor, histogenetically unrelated. Although extrarenal forms of this tumor are rare, several examples have been described in other sites, especially the liver, prostate, paravertebral area, urinary bladder and soft tissue. We experienced a case of malignant rhabdiod tumor located in the intraabdominal cavity in a 10 month-old boy. Smear of peritoneal fluid showed round, polygonal and irregular shaped cells with large nuclei, ample cytoplasm containing light pink to purple cytoplasmic inclusions, and one or a few prominent nucleoli. Immunocytochemistry revealed positivity to cytokeratin, epithelial membrane antigen and vimentin, and negativity to desmin and neuron-specific enolase. These distinct cytologic appearance and immunophenotypes were most consistent with a diagnosis of extrarenal malignant rhabdoid tumor. The cytoplasmic inclusions were correlated with eosinophilic inclusions seen in histologic section and electron microscopy confirmed this interpretation, showing filamentous aggregations in the cytoplasms of the tumor cells.

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