• 한국자기공명학회논문지
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• 제21권3호
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• pp.102-108
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• 2017

Escherichia coli responds to ever-changing external and internal stresses by rapidly adjusting its physiology for better survival. This adjustment occurs at all levels including metabolites as well as mRNAs and proteins. Although there has been many reports describing E. coli's adaptation to various stresses regarding transcriptomics or proteomics, only a few investigations have been reported regarding this adaptation viewed from metabolites' perspective. We applied four different types of stresses at four different doses as imposed by NaCl, sorbitol, ethanol, and pH to investigate the similarities or differences among the stresses, and which stress causes the largest perturbation of the metabolite composition. We profiled the metabolites under such external stresses by using two-dimensional NMR spectroscopy and identified 39 metabolites including amino acids, sugars, organic acids, and nucleic acids. According to our statistical analysis, the osmotic stress caused by sorbitol differentiated itself from others, while NaCl showed the largest dose dependent metabolic perturbations. We hope this work will form a foundation on which an approach to a successful protein production is systematically provided by a favorable metabolic environment by imposing proper external stresses.

• 한국정밀공학회지
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• 제18권11호
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• pp.107-115
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• 2001

Most of rotating machineries supported by contact bearing accompany lowering efficiency, vibration and wear. Moreover, because of vibration, which is occurred in rotating shaft, they have the limits of driving speed and precision. The rotor system has parametric variations or external disturbances such as mass unbalance variations in long operation. Therefore, it is necessary to research about magnetic bearing, which is able to support the shaft without mechanical contact and to control rotor vibration without being affected by external disturbances or parametric changes. Magnetic bearing system in the paper is composed of position sensor, digital controller, actuating amplifier and electromagnet. This paper applied the robust control method using quantitative feedback theory (QFT) to control the magnetic bearing. It also proposed design skill of optimal controller, in case the system has structured uncertainty, unstructured uncertainty and disturbance. Reduction of vibration is verified at critical rotating speed even external disturbance exists. Unbalance response, a serious problem in rotating machinery, is improved by magnetic bearing using QFT algorithm.

• 천문학회보
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• 제44권1호
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• pp.74.3-75
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• 2019

Recent Integral Field Spectroscopy (IFS) studies revealed that not only late type galaxies (LTGs) but also early type galaxies (ETGs) have various kinds of kinematic rotation. (e.g. not clearly detectable rotation, disk-like rotation, kinematically distinct core (Cappellari 06)) Among the various studies about galactic kinematics, one of the most notable anomalies is the star-gas misalignment. The gas forms stars and stars release gas through mass-loss. In this process, their angular momentum is conserved. Therefore, kinematic decoupling between stars and gas can occur due to external gas inflow or perturbation of components. There are some possible origins of misalignment: cold gas from filaments, hot gas from outer halo, interaction or merging events with galaxies and environmental effects. Misalignment, the black box from mixture of internal and external gas, can be an important keyword for understanding further about galaxies' kinematics and external processes. Using both SAMI IFS data(Sydney-AAO Multi-object Integral field spectrograph Galaxy Survey, Croom+12) and Horizon-AGN simulation(Dubois+14), we examined misaligned galaxies properties and distribution. Because the simulation has lots of galaxies at various z, we were able to study history of formation, evolution and extinction of misalignment, which was hard to be done with observation only.

• Steel and Composite Structures
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• 제51권5호
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• pp.473-485
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• 2024

This paper proposes a composite form of fuzzy adaptive control plan based on a robust observer. The fuzzy 2D control gains are regulated by the parameters in the LMIs. Then, control and learning performance indices with weight matrices are constructed as the cost functions, which allows the regulation of the trade-off between the two performance by setting appropriate weight matrices. The design of 2D control gains is equivalent to the LMIs-constrained multi-objective optimization problem under dual performance indices. By using this proposed smart tracking design via fuzzy nonlinear criterion, the data link can be further extended. To evaluate the performance of the controller, the proposed controller was compared with other control technologies. This ensures the execution of the control program used to track position and trajectory in the presence of great model uncertainty and external disturbances. The performance of monitoring and control is verified by quantitative analysis. The goals of this paper are towards access to adequate, safe and affordable housing and basic services, promotion of inclusive and sustainable urbanization and participation, implementation of sustainable and disaster-resilient buildings, sustainable human settlement planning and manage. Therefore, the goal is believed to achieved in the near future by the ongoing development of AI and control theory.

• 대한화학회지
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• 제47권5호
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• pp.447-459
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• 2003

일반화된 이차원 상관 분광학은 모든 분자 분광학 즉, 적외선 (infrared, IR), 근적외선 (near-infrared, NIR), 라만 (Raman) 및 형광 (fluorescence) 분광학뿐만 아니라 X-ray 회절, X-ray 흡수 분광학 (XAS), 크로마토그래피 (chromatography) 등에 적용되어 시간뿐만 아니라 온도, 압력, 농도, 조성과 같은 다른 물리적 변화인 외부 섭동 (perturbation) 아래에서 얻은 스펙트럼 분석의 새로운 분광학으로 다양한 분야의 연구가 활발히 진행 중이다. 또한 같은 외부 섭동 아래에서 얻은 완전히 다른 두 스펙트럼의 2D hetero-spectral correlation analysis가 가능하므로 다양한 분야 즉, 생체 물질, 고분자, 나노입자 등의 연구가 활발히 진행 중이다. 이런 다양한 분야의 응용성 때문에 ？일반？?이차원 상관 분광학？？물리, 분석, 고분자, 나노물질 및 생화학 연구에 새로운 방향을 제시할 수 있을 뿐만 아니라 바이오 나노기술 연구에 상승 효과를 제공할 수 있다. 본 논문은 "일반화된 이차원 상관 분광학"의 원리와 그 다양한 응용성을 본 저자들의 연구를 중심으로 소개하고자 한다.

• Advances in nano research
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• 제15권3호
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• pp.215-224
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• 2023

Nonlinearity plays an important role in control systems and the application of design. For this reason, in addition to linear vibrations, nonlinear vibrations of the stepped nanobeam are also discussed in this manuscript. This study investigated the vibrations of stepped nanobeams according to Eringen's nonlocal elasticity theory. Eringen's nonlocal elasticity theory was used to capture the nanoscale effect. The nanoscale stepped Euler Bernoulli beam is considered. The equations of motion representing the motion of the beam are found by Hamilton's principle. The equations were subjected to nondimensionalization to make them independent of the dimensions and physical structure of the material. The equations of motion were found using the multi-time scale method, which is one of the approximate solution methods, perturbation methods. The first section of the series obtained from the perturbation solution represents a linear problem. The linear problem's natural frequencies are found for the simple-simple boundary condition. The second-order part of the perturbation solution is the nonlinear terms and is used as corrections to the linear problem. The system's amplitude and phase modulation equations are found in the results part of the problem. Nonlinear frequency-amplitude, and external frequency-amplitude relationships are discussed. The location of the step, the radius ratios of the steps, and the changes of the small-scale parameter of the theory were investigated and their effects on nonlinear vibrations under simple-simple boundary conditions were observed by making comparisons. The results are presented via tables and graphs. The current beam model can assist in designing and fabricating integrated such as nano-sensors and nano-actuators.

• 대한전기학회논문지:시스템및제어부문D
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• 제54권10호
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• pp.587-594
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• 2005

An adaptive observer for rotor resistance is designed to estimate rotor flux for the a-b model of an induction motor assuming that rotor speed and stator currents are measurable. A singularly perturbed model of the motor is used to design an Adaptive sliding mode observer which drives the estimated stator currents to their true values in the fast time scale. The adaptive observer on the sliding surface is based on the equivalent switching vector and both the estimated fluxes and the estimated rotor resistance converge to their true values. A speed controller considering the effects of parameter variations and external disturbance is proposed in this paper. First, induction motor dynamic model at nominal case is estimated. based on the estimated model, speed controller is designed to match the prescribed speed tracking specifications. Then a dead-time compensator and a robust controller are designed to reduce the effects of parameter variations and external disturbances. the desired speed tracking control performance can be preserved under wide operating range, and good speed load regulating performance. Some simulated results are provided to demonstrate the effectiveness of the Proposed controller.

• 한국생물정보학회:학술대회논문집
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• 한국생물정보시스템생물학회 2005년도 BIOINFO 2005
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• pp.191-196
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• 2005

Genetic networks are a key to unraveling dynamic properties of biological processes and regulation of genes plays an essential role in dynamic behavior of the genetic networks. A popular characterization of regulation of the gene is a kinetic model. However, many kinetic parameters in the genetic regulation have not been available. To overcome this difficulty, in this report, state-space approach to modeling gene regulation is presented. Second-order systems are used to characterize gene regulation. Interpretation of coefficients in the second order systems as resistance, capacitance and inductance is studied. The mathematical methods for transient response analysis of gene regulation to external perturbation are investigated. Criterion for classifying gene into three categories: underdamped, overdamped and critical damped is discussed. The proposed models are applied to yeast cell cycle gene expression data.

• 대한수학회지
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• 제52권6호
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• pp.1149-1159
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• 2015

This paper is concerned with a generalized 2D parabolic equation with a nonautonomous perturbation $$-{\Delta}u_t+{\alpha}^2{\Delta}^2u_t+{\mu}{\Delta}^2u+{\bigtriangledown}{\cdot}{\vec{F}}(u)+B(u,u)={\epsilon}g(x,t)$$. Under some proper assumptions on the external force term g, the upper semicontinuity of pullback attractors is proved. More precisely, it is shown that the pullback attractor $\{A_{\epsilon}(t)\}_{t{\epsilon}{\mathbb{R}}}$ of the equation with ${\epsilon}>0$ converges to the global attractor A of the equation with ${\epsilon}=0$.

• Tribology and Lubricants
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• 제23권4호
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• pp.162-169
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• 2007

This paper deals with friction effects on the performance of double-bumped AFBs. The stiffness and damping coefficients of the double bump vary depending on the external load and its friction coefficient. The double bump can be either in the single or double active region depending on vertical deflection. The equivalent stiffness and damping coefficients of the bump system are derived from the vertical and horizontal deflection of the bump, including the friction effect. A static and dynamic performance analysis is carried out by using the finite difference method and the perturbation technique. The results of the performance analysis for a double-bumped AFB are compared with those obtained for a single-bumped AFB. This paper successfully proves that a double bumped AFB has higher load capacity, stiffness, and damping than a single-bumped AFB in a heavily loaded condition.