• Journal of the Korean Magnetic Resonance Society
• /
• v.21 no.3
• /
• pp.102-108
• /
• 2017

Escherichia coli responds to ever-changing external and internal stresses by rapidly adjusting its physiology for better survival. This adjustment occurs at all levels including metabolites as well as mRNAs and proteins. Although there has been many reports describing E. coli's adaptation to various stresses regarding transcriptomics or proteomics, only a few investigations have been reported regarding this adaptation viewed from metabolites' perspective. We applied four different types of stresses at four different doses as imposed by NaCl, sorbitol, ethanol, and pH to investigate the similarities or differences among the stresses, and which stress causes the largest perturbation of the metabolite composition. We profiled the metabolites under such external stresses by using two-dimensional NMR spectroscopy and identified 39 metabolites including amino acids, sugars, organic acids, and nucleic acids. According to our statistical analysis, the osmotic stress caused by sorbitol differentiated itself from others, while NaCl showed the largest dose dependent metabolic perturbations. We hope this work will form a foundation on which an approach to a successful protein production is systematically provided by a favorable metabolic environment by imposing proper external stresses.

• Journal of the Korean Society for Precision Engineering
• /
• v.18 no.11
• /
• pp.107-115
• /
• 2001

Most of rotating machineries supported by contact bearing accompany lowering efficiency, vibration and wear. Moreover, because of vibration, which is occurred in rotating shaft, they have the limits of driving speed and precision. The rotor system has parametric variations or external disturbances such as mass unbalance variations in long operation. Therefore, it is necessary to research about magnetic bearing, which is able to support the shaft without mechanical contact and to control rotor vibration without being affected by external disturbances or parametric changes. Magnetic bearing system in the paper is composed of position sensor, digital controller, actuating amplifier and electromagnet. This paper applied the robust control method using quantitative feedback theory (QFT) to control the magnetic bearing. It also proposed design skill of optimal controller, in case the system has structured uncertainty, unstructured uncertainty and disturbance. Reduction of vibration is verified at critical rotating speed even external disturbance exists. Unbalance response, a serious problem in rotating machinery, is improved by magnetic bearing using QFT algorithm.

• The Bulletin of The Korean Astronomical Society
• /
• v.44 no.1
• /
• pp.74.3-75
• /
• 2019

Recent Integral Field Spectroscopy (IFS) studies revealed that not only late type galaxies (LTGs) but also early type galaxies (ETGs) have various kinds of kinematic rotation. (e.g. not clearly detectable rotation, disk-like rotation, kinematically distinct core (Cappellari 06)) Among the various studies about galactic kinematics, one of the most notable anomalies is the star-gas misalignment. The gas forms stars and stars release gas through mass-loss. In this process, their angular momentum is conserved. Therefore, kinematic decoupling between stars and gas can occur due to external gas inflow or perturbation of components. There are some possible origins of misalignment: cold gas from filaments, hot gas from outer halo, interaction or merging events with galaxies and environmental effects. Misalignment, the black box from mixture of internal and external gas, can be an important keyword for understanding further about galaxies' kinematics and external processes. Using both SAMI IFS data(Sydney-AAO Multi-object Integral field spectrograph Galaxy Survey, Croom+12) and Horizon-AGN simulation(Dubois+14), we examined misaligned galaxies properties and distribution. Because the simulation has lots of galaxies at various z, we were able to study history of formation, evolution and extinction of misalignment, which was hard to be done with observation only.

• Journal of the Korean Chemical Society
• /
• v.47 no.5
• /
• pp.447-459
• /
• 2003

Generalized 2D correlation spectroscopy has been applied extensively to the analysis of spectral data sets obtained during the observation of a system under some external perturbation. It is used in various fields of spectroscopy including IR, Raman, UV, fluorescence, X-ray diffraction, and X-ray absorption spectroscopy (XAS) as well as chromatography. 2D hetero-spectral correlation analysis compares two completely different types of spectra obtained for a system under the same perturbation. Because of the wide range of applications of this technique, it has become one of the standard analytical techniques for the analytical chemistry, physical chemistry, biochemistry, and so on, and for studies of polymers, biomolecules, nanomaterials, etc. In this paper, we will introduce the principle of generalized 2D correlation spectroscopy and its applications that we have studied.

• Advances in nano research
• /
• v.15 no.3
• /
• pp.215-224
• /
• 2023

Nonlinearity plays an important role in control systems and the application of design. For this reason, in addition to linear vibrations, nonlinear vibrations of the stepped nanobeam are also discussed in this manuscript. This study investigated the vibrations of stepped nanobeams according to Eringen's nonlocal elasticity theory. Eringen's nonlocal elasticity theory was used to capture the nanoscale effect. The nanoscale stepped Euler Bernoulli beam is considered. The equations of motion representing the motion of the beam are found by Hamilton's principle. The equations were subjected to nondimensionalization to make them independent of the dimensions and physical structure of the material. The equations of motion were found using the multi-time scale method, which is one of the approximate solution methods, perturbation methods. The first section of the series obtained from the perturbation solution represents a linear problem. The linear problem's natural frequencies are found for the simple-simple boundary condition. The second-order part of the perturbation solution is the nonlinear terms and is used as corrections to the linear problem. The system's amplitude and phase modulation equations are found in the results part of the problem. Nonlinear frequency-amplitude, and external frequency-amplitude relationships are discussed. The location of the step, the radius ratios of the steps, and the changes of the small-scale parameter of the theory were investigated and their effects on nonlinear vibrations under simple-simple boundary conditions were observed by making comparisons. The results are presented via tables and graphs. The current beam model can assist in designing and fabricating integrated such as nano-sensors and nano-actuators.

• The Transactions of the Korean Institute of Electrical Engineers D
• /
• v.54 no.10
• /
• pp.587-594
• /
• 2005

An adaptive observer for rotor resistance is designed to estimate rotor flux for the a-b model of an induction motor assuming that rotor speed and stator currents are measurable. A singularly perturbed model of the motor is used to design an Adaptive sliding mode observer which drives the estimated stator currents to their true values in the fast time scale. The adaptive observer on the sliding surface is based on the equivalent switching vector and both the estimated fluxes and the estimated rotor resistance converge to their true values. A speed controller considering the effects of parameter variations and external disturbance is proposed in this paper. First, induction motor dynamic model at nominal case is estimated. based on the estimated model, speed controller is designed to match the prescribed speed tracking specifications. Then a dead-time compensator and a robust controller are designed to reduce the effects of parameter variations and external disturbances. the desired speed tracking control performance can be preserved under wide operating range, and good speed load regulating performance. Some simulated results are provided to demonstrate the effectiveness of the Proposed controller.

• Proceedings of the Korean Society for Bioinformatics Conference
• /
• 2005.09a
• /
• pp.191-196
• /
• 2005

Genetic networks are a key to unraveling dynamic properties of biological processes and regulation of genes plays an essential role in dynamic behavior of the genetic networks. A popular characterization of regulation of the gene is a kinetic model. However, many kinetic parameters in the genetic regulation have not been available. To overcome this difficulty, in this report, state-space approach to modeling gene regulation is presented. Second-order systems are used to characterize gene regulation. Interpretation of coefficients in the second order systems as resistance, capacitance and inductance is studied. The mathematical methods for transient response analysis of gene regulation to external perturbation are investigated. Criterion for classifying gene into three categories: underdamped, overdamped and critical damped is discussed. The proposed models are applied to yeast cell cycle gene expression data.

• Journal of the Korean Mathematical Society
• /
• v.52 no.6
• /
• pp.1149-1159
• /
• 2015

This paper is concerned with a generalized 2D parabolic equation with a nonautonomous perturbation $$-{\Delta}u_t+{\alpha}^2{\Delta}^2u_t+{\mu}{\Delta}^2u+{\bigtriangledown}{\cdot}{\vec{F}}(u)+B(u,u)={\epsilon}g(x,t)$$. Under some proper assumptions on the external force term g, the upper semicontinuity of pullback attractors is proved. More precisely, it is shown that the pullback attractor $\{A_{\epsilon}(t)\}_{t{\epsilon}{\mathbb{R}}}$ of the equation with ${\epsilon}>0$ converges to the global attractor A of the equation with ${\epsilon}=0$.

• Tribology and Lubricants
• /
• v.23 no.4
• /
• pp.162-169
• /
• 2007

This paper deals with friction effects on the performance of double-bumped AFBs. The stiffness and damping coefficients of the double bump vary depending on the external load and its friction coefficient. The double bump can be either in the single or double active region depending on vertical deflection. The equivalent stiffness and damping coefficients of the bump system are derived from the vertical and horizontal deflection of the bump, including the friction effect. A static and dynamic performance analysis is carried out by using the finite difference method and the perturbation technique. The results of the performance analysis for a double-bumped AFB are compared with those obtained for a single-bumped AFB. This paper successfully proves that a double bumped AFB has higher load capacity, stiffness, and damping than a single-bumped AFB in a heavily loaded condition.

• Proceedings of the KIPE Conference
• /
• 2004.07a
• /
• pp.147-150
• /
• 2004

Maximum power point tracking for PV systems traditionally uses either perturbation and observation method or incremental conductance method. Both methods require modulation of the output voltage and this leads to significant power loss. In this paper, a method, which senses output circuit voltage and short circuit current and use the above two parameters for optimum control with a fuzzy controller, is introduced. The short circuit current of PV cell represents illumination, and the output circuit voltage carry on information about the temperature. PCS(power conditioning system) is controlled not only feed to inverter for stability voltage variation despite of variety external environment, but also operate in order to feeding voltage and current at maximum power point by boost type chopper.