• Title/Summary/Keyword: External Validation

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Determination of Protein Content in Pea by Near Infrared Spectroscopy

  • Lee, Jin-Hwan;Choung, Myoung-Gun
    • Food Science and Biotechnology
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    • v.18 no.1
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    • pp.60-65
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    • 2009
  • Near infrared reflectance spectroscopy (NIRS) was used as a rapid and non-destructive method to determine the protein content in intact and ground seeds of pea (Pisum sativum L.) germplasms grown in Korea. A total of 115 samples were scanned in the reflectance mode of a scanning monochromator at intact seed and flour condition, and the reference values for the protein content was measured by auto-Kjeldahl system. In the developed ground and intact NIRS equations for analysis of protein, the most accurate equation were obtained at 2, 8, 6, 1 math treatment conditions with standard normal variate and detrend scatter correction method and entire spectrum (400-2,500 nm) by using modified partial least squares regression (n=78). External validation (n=34) of these NIRS equations showed significant correlation between reference values and NIRS estimated values based on the standard error of prediction (SEP), $R^2$, and the ratio of standard deviation of reference data to SEP. Therefore, these ground and intact NIRS equations can be applicable and reliable for determination of protein content in pea seeds, and non-destructive NIRS method could be used as a mass analysis technique for selection of high protein pea in breeding program and for quality control in food industry.

Multi-scale wireless sensor node for health monitoring of civil infrastructure and mechanical systems

  • Taylor, Stuart G.;Farinholt, Kevin M.;Park, Gyuhae;Todd, Michael D.;Farrar, Charles R.
    • Smart Structures and Systems
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    • v.6 no.5_6
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    • pp.661-673
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    • 2010
  • This paper presents recent developments in an extremely compact, wireless impedance sensor node (the WID3, $\underline{W}$ireless $\underline{I}$mpedance $\underline{D}$evice) for use in high-frequency impedance-based structural health monitoring (SHM), sensor diagnostics and validation, and low-frequency (< ~1 kHz) vibration data acquisition. The WID3 is equipped with an impedance chip that can resolve measurements up to 100 kHz, a frequency range ideal for many SHM applications. An integrated set of multiplexers allows the end user to monitor seven piezoelectric sensors from a single sensor node. The WID3 combines on-board processing using a microcontroller, data storage using flash memory, wireless communications capabilities, and a series of internal and external triggering options into a single package to realize a truly comprehensive, self-contained wireless active-sensor node for SHM applications. Furthermore, we recently extended the capability of this device by implementing low-frequency analog-to-digital and digital-to-analog converters so that the same device can measure structural vibration data. The compact sensor node collects relatively low-frequency acceleration measurements to estimate natural frequencies and operational deflection shapes, as well as relatively high-frequency impedance measurements to detect structural damage. Experimental results with application to SHM, sensor diagnostics and low-frequency vibration data acquisition are presented.

Prediction of Type 2 Diabetes Remission after Bariatric or Metabolic Surgery

  • Park, Ji Yeon
    • Journal of Obesity & Metabolic Syndrome
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    • v.27 no.4
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    • pp.213-222
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    • 2018
  • Bariatric surgery has evolved from a surgical measure for treating morbid obesity to an epochal remedy for treating metabolic syndrome as a whole, which is represented by type 2 diabetes mellitus. Numerous clinical trials have advocated bariatric or metabolic surgery over nonsurgical interventions because of markedly superior metabolic outcomes in morbidly obese patients who satisfy traditional criteria for bariatric surgery (body mass index [BMI] >$35kg/m^2$) and in less obese or simply overweight patients. Nevertheless, not all diabetes patients achieve the most desirable outcomes; i.e., diabetes remission after metabolic surgery. Thus, candidates for metabolic surgery should be carefully selected based on comprehensive preoperative assessments of the risk-benefit ratio. Predictors for diabetes remission after metabolic surgery may be classified into two groups based on mechanism of action. The first is indices for preserved pancreatic beta-cell function, including younger age, shorter duration of diabetes, and higher C-peptide level. The second is the potential for an insulin resistance reduction, including higher baseline BMI and visceral fat area. Several prediction models for diabetes remission have been suggested by merging these two to guide the joint decision-making process between clinicians and patients. Three such models, DiaRem, ABCD, and individualized metabolic surgery scores, provide an intuitive scoring system and have been validated in an independent external cohort and can be utilized in routine clinical practice. These prediction models need further validation in various ethnicities to ensure universal applicability.

An improved Kalman filter for joint estimation of structural states and unknown loadings

  • He, Jia;Zhang, Xiaoxiong;Dai, Naxin
    • Smart Structures and Systems
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    • v.24 no.2
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    • pp.209-221
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    • 2019
  • The classical Kalman filter (KF) provides a practical and efficient way for state estimation. It is, however, not applicable when the external excitations applied to the structures are unknown. Moreover, it is known the classical KF is only suitable for linear systems and can't handle the nonlinear cases. The aim of this paper is to extend the classical KF approach to circumvent the aforementioned limitations for the joint estimation of structural states and the unknown inputs. On the basis of the scheme of the classical KF, analytical recursive solution of an improved KF approach is derived and presented. A revised form of observation equation is obtained basing on a projection matrix. The structural states and the unknown inputs are then simultaneously estimated with limited measurements in linear or nonlinear systems. The efficiency and accuracy of the proposed approach is verified via a five-story shear building, a simply supported beam, and three sorts of nonlinear hysteretic structures. The shaking table tests of a five-story building structure are also employed for the validation of the robustness of the proposed approach. Numerical and experimental results show that the proposed approach can not only satisfactorily estimate structural states, but also identify unknown loadings with acceptable accuracy for both linear and nonlinear systems.

Endoscopic slide-in orbital wall reconstruction for isolated medial blowout fractures

  • Kim, Taewoon;Kim, Baek-Kyu
    • Archives of Craniofacial Surgery
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    • v.21 no.6
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    • pp.345-350
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    • 2020
  • Background: This study evaluated the efficacy of the endoscopic medial orbital wall repair by comparing it with the conventional transcaruncular method. This surgical approach differs from the established endoscopic technique in that we push the mesh inside the orbit rather than placing it over the defect. Methods: We retrospectively reviewed 40 patients with isolated medial orbital blowout fractures who underwent medial orbital wall reconstruction. Twenty-six patients underwent endoscopic repair, and 14 patients underwent external repair. All patients had preoperative computed tomography scans taken to determine the defect size. Pre- and postoperative exophthalmometry, operation time, the existence of diplopia, and pain were evaluated and compared between the two methods. We present a case showing our procedure. Results: The operation time was significantly shorter in the endoscopic group (44.7 minutes vs. 73.9 minutes, p= 0.035). The preoperative defect size, enophthalmos correction rate, and pain did not significantly differ between the two groups. All patients with preoperative diplopia, eyeball movement limitation, or enophthalmos had their symptoms resolved, except for one patient who had preexisting strabismus. Conclusion: This study demonstrates that endoscopic medial orbital wall repair is not inferior to the transcaruncular method. The endoscopic approach seems to reduce the operation time, probably because the dissection process is shorter, and no wound repair is needed. Compared to the previous endoscopic method, our method is not complicated, and is more physiological. Larger scale studies should be performed for validation.

Translation and psychometric evaluation of the Korean version of the fertility awareness and attitudes towards parenthood questionnaire

  • Shin, Hyewon;Hong, Minjoo;Jo, Minjeong;Lee, Jungmin
    • Child Health Nursing Research
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    • v.27 no.3
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    • pp.256-265
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    • 2021
  • Purpose: This study presents a translation, cultural adaptation, and psychometric evaluation of two instruments of the Fertility Awareness and Attitudes Towards Parenthood (FAAP) questionnaire (Conditions and Life changes) for use in South Korea. Methods: This methodological study included 166 university students for psychometric evaluation in the sixth step. The first five steps included forward translation, backward translation, committee review, assessment of content validity, and a pre-test. In the sixth step, psychometric properties, including internal consistency, construct validity, and criterion validity, were evaluated. Exploratory factor analysis and confirmatory factor analysis were conducted to identify the structure of the tool and to assess its validity. Results: The Korean version showed acceptable internal consistency. Cronbach's α was .73 for FAAP-Conditions and .83 for FAAP-Life changes. FAAP-Conditions showed a four-factor structure (social conditions, relationship with partner, external environment, and child-rearing support) and FAAP-Life changes had a two-factor structure (reward and burden). In the confirmatory analysis, CMIN/DF, TLI, IFI, SRMR, CFI, and RMSEA were satisfactory. Conclusion: This study provided preliminary evidence of the acceptability, reliability, and validity of the Korean version of the FAAP questionnaire in university students in South Korea. Nonetheless, further evaluation among Korean young adults is warranted to validate this instrument.

Development of Image Segmentation Model for Sarcopenia Diagnosis and Its External Validation (근감소증 진단을 위한 영상분할 모델 개발 및 외부검증)

  • Lee, Chung-sub;Lim, Dong-Wook;Kim, Ji-Eon;Noh, Si-Hyeong;Yu, Yeong-Ju;Kim, Tae-Hoon;Jeong, Chang-Won
    • Proceedings of the Korea Information Processing Society Conference
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    • 2022.05a
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    • pp.535-538
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    • 2022
  • 근감소증은 영양부족, 운동량 감소 그리고 노화 등으로 정상적인 근육의 양과 근력 및 근 기능이 감소하는 질환을 말한다. 근감소증은 보편적으로 유럽 근감소증 실무그룹분석(EWGSOP)에서 정의한 측정 방법을 따른다. 본 논문에서는 근감소증 진단을 위한 영상 분할 모델을 개발하고 외부검증하는 방법에 대해서 제안한다. 우리는 CT 영상에서 L3 영역을 선별하여 자동으로 근육, 피하지방, 내장지방을 분할할 수 있는 인공지능 모델을 U-Net을 사용하여 개발하였다. 또한 모델의 성능을 평가하기 위해서 분할영역의 IOU(Intersection over Union)를 계산하여 내부검증을 진행하였으며, 타 병원의 데이터를 이용하여 같은 방법으로 외부검증을 진행한 결과를 보인다. 검증 결과를 토대로 문제점과 해결방안에 대해서 고찰하고 보완하고자 했다.

Thermal-hydraulic 0D/3D coupling in OpenFOAM: Validation and application in nuclear installations

  • Santiago F. Corzo ;Dario M. Godino ;Alirio J. Sarache Pina;Norberto M. Nigro ;Damian E. Ramajo
    • Nuclear Engineering and Technology
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    • v.55 no.5
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    • pp.1911-1923
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    • 2023
  • The nuclear safety assessment involving large transient simulations is forcing the community to develop methods for coupling thermal-hydraulics and neutronic codes and three-dimensional (3D) Computational Fluid Dynamics (CFD) codes. In this paper a set of dynamic boundary conditions are implemented in OpenFOAM in order to apply zero-dimensional (0D) approaches coupling with 3D thermal-hydraulic simulation in a single framework. This boundary conditions are applied to model pipelines, tanks, pumps, and heat exchangers. On a first stage, four tests are perform in order to assess the implementations. The results are compared with experimental data, full 3D CFD, and system code simulations, finding a general good agreement. The semi-implicit implementation nature of these boundary conditions has shown robustness and accuracy for large time steps. Finally, an application case, consisting of a simplified open pool with a cooling external circuit is solved to remark the capability of the tool to simulate thermal hydraulic systems commonly found in nuclear installations.

Integration of BIM and Simulation for optimizing productivity and construction Safety

  • Evangelos Palinginis;Ioannis Brilakis
    • International conference on construction engineering and project management
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    • 2013.01a
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    • pp.21-27
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    • 2013
  • Construction safety is a predominant hindrance in in-situ workflow and considered an unresolved issue. Current methods used for safety optimization and prediction, with limited exceptions, are paper-based, thus error prone, as well as time and cost ineffective. In an attempt to exploit the potential of BIM for safety, the objective of the proposed methodology is to automatically predict hazardous on-site conditions related to the route that the dozers follow during the different phases of the project. For that purpose, safety routes used by construction equipment from an origin to multiple destinations are computed using video cameras and their cycle times are calculated. The cycle times and factors; including weather and light conditions, are considered to be independent and identically distributed random variables (iid); and simulated using the Arena software. The simulation clock is set to 100 to observe the minor changes occurring due to external parameters. The validation of this technology explores the capabilities of BIM combined with simulation for enhancing productivity and improving safety conditions a-priori. Preliminary results of 262 measurements indicate that the proposed methodology has the potential to predict with 87% the location of exclusion zones. Also, the cycle time is estimated with an accuracy of 89%.

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A Study on the Development of a MOOC Design Model

  • LEE, Gayoung;KEUM, Sunyoung;KIM, Myungsun;CHOI, Yoomi;RHA, Ilju
    • Educational Technology International
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    • v.17 no.1
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    • pp.1-37
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    • 2016
  • The purpose of this study was to develop a MOOC design model that would improve the current practice of MOOC development in Korea by specifying easy-to-use course development procedures and guiding strategies. Following Richey and Klein (2007)'s conceptual model development procedure, the first step was to perform critical review of relevant literature and observe typical MOOC development processes. As a result, the initial model was developed. The second step was to conduct the expert review with five educational technology and MOOC researchers to secure the internal validity of the model. Based on the experts' suggestions, the model was revised and once again reviewed by the same experts. This process resulted in the development of the 2nd version of model. The third step was to carry out external validation research in order to test the effectiveness, efficiency, and usability of the model. A basic model may be confirmed or corrected based on examination of its results. Consequently, the model was elaborated as the final model. In the final model, 6 procedural phases and 9 specific steps were included. The six procedural phases are: Analysis (1st Iteration), Design, Development (Course Development), Implementation, Evaluation, and Analysis (2nd Iteration), a slight variation of ADDIE model. The specific steps include: 1) Goal Setting, 2) Environment Analysis, 3) Content Design, 4) Style Design, 5) Course Development, 6) Implementation Plan, 7) Course Implementation, 8) Summative Evaluation, and 9) Need Reflection. The study concluded with suggestions for further research and application of the MOOC design model.