• 생명과학회지
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• 제8권2호
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• pp.226-226
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• 1998

Molecular chaperone의 발견은 생명과학자들에게 살아있는 세포 내에서 어떻게 생체활성단백질이 만들어지고 유지되는지에 대한 자극과 함께 그것을 증명하기 위한 실험동기를 부여하였다. 초기에는 Molecular chaperone이 nucleosomes의 assembly에 관여하는 단백질을 설명하기 위하여 사용되었으나, 지금은 기본적인 세포생리기능의 하나인 단백질의 folding과 assembly를 돕는 assistant protein으로 주로 사용된다. 단백질합성 뿐만 아니라 단백질수송, oligomeric structure의 assembly와 disassembly, heat shock을 포함한 각종 내, 외부스트래스에 의해서 변성된 단백질의 세로내분화와 회복에도 Molecular chaperone이 관여하고 있다. 그러나 아직까지는 Molecular chaperone들의 3차구조와 그들간의 상호작용에 관한 정보가 부족하여 크게 진전되지 못하고 있지만, 많은 연구자에 의한 정보축적으로 인하여 빠른 시일 내에 Molecular chaperone에 세포내역할이 분명하게밝혀질 것이다.

• 태양에너지
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• 제18권3호
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• pp.197-203
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• 1998

A 5 ton/day pilot scale two-phase anaerobic digester was constructed and tasted to treat Korean food wastes in Anyang city. The process was developed based on 3 years of lab-scale experimental results on am optimim treatment method for the recovery of biogas and humus. Problems related to food waste are ever Increasing quantity among municipal solid wastes(MSW) and high moisture and salt contents. Thus our food waste produces large amounts of leachate and bed odor in landfill sites which are being exhausted. The easily degradable presorted food waste was efficiently treated in the two-phase anaerobic digestion process. The waste contained in plastic bags was shredded and then screened for the removal of inert material such as fabrics and plastics, and subsequently put into the two-stage reactors. Heavy and light inerts such as bones, shells, spoons and plastic pieces were again removed by gravity differences. The residual organic component was effectively hydrolyzed and acidified in the first reactor with 5 days space time at pH of about 6.5. The second, methanization reactor part of which is filled with anaerobic fillters, converted the acids into methane with pH between 7.4 to 7.8. The space time for the second reactor was 15 days. The effluent from the second reactor was recycled to the first reactor to provide alkalinities. The process showed stable steady state operation with the maximum organic rate of 7.9 $kgVS/m^3day$ and the volatile solid reduction efficiency of about 70%. The total of 3.6 tons presorted MSW containing 2.9 tons of food organic was treated to produce about $230m^3$ of biogas with 70% of methane and 80kg humus. This process is extended to full scale treating 15 tons of food waste a day in Euiwang city and the produced biogas is utilized for the heating/cooling of adjacent buildings.

• 대한구순구개열학회지
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• 제9권2호
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• pp.79-84
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• 2006

Cleft palate is one of the most devastating congenital facial deformities frequently accompanied by cleft lip. In many cases, it causes phonetic and swallowing difficulties although surgical interventionwas applied. Among the surgical methods, Veau-Wardill-Kilner pushback palatoplasty (V-Y reposition) is widely used in the most cleft palate cases. It is designed to lengthen the palate posteriorly, hence to overcome the speech and swallowing problems, but broad postoperative palatal scar might interfere the normal maxillary growth. If the velar muscles were not reoriented, it could result in incomplete speech recovery. In this case report, the modified two-flap palatoplasty with minimal pushback was successfully applied to a 21 month-old girl who has had incomplete cleft palate extended to the posterior third of hard palate. The speech evaluation was confirmed as functional reconstruction of cleft palate was achieved.

• Bulletin of the Korean Chemical Society
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• 제33권11호
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• pp.3727-3734
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• 2012

An analytical method has been developed for the rapid determination of perfluorinated compounds (PFCs) in human serum samples. The extraction and purification of PFCs from human serum were performed by the modified method of previous report. Ten PFCs were rapidly separated within 3.3 min by C18-monolithic column liquid chromatography (LC) and detected by electrospray ionization (ESI) tandem mass spectrometry (MS/MS) in negative ion mode. The runtime of PFCs on monolithic column LC was up to 4-fold faster than that on conventional column LC. The effect of triethylamine (TEA) to the mobile phase has investigated on the overall MS detection sensitivity of PFCs in ESI ionization. Quantification was performed by LC-MS/MS in multiple-ion reaction monitoring (MRM) mode, using $^{13}C$-labeled internal standards. Method validation was performed to determine recovery, linearity, precision, and limits of quantification, followed by, the analysis of a standard reference material (SRM 1957 from NIST). The overall recoveries ranged between 81.5 and 106.3% with RSDs of 3.4 to 16.2% for the entire procedure. The calibration range extended from 0.33 to 50 $ng\;mL^{-1}$, with a correlation coefficient ($R^2$) greater than 0.995 and the limits of quantification with 0.08 to 0.46 $ng\;mL^{-1}$. This approach can be used for rapid and sensitive quantitative analysis of 10 PFCs in human serum with high performance and accuracy.

• 전자공학회지
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• 제22권8호
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• pp.33-43
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• 1995

생산시스템 분야에서의 다중로봇시스템에 대한 필요성이 증가되고 있기 때문에, 이에 대한 시스템 성능분석이 우선적으로 필요하다. 본 논문에서는 다중로봇시스템의 성능평가를 위한 컴퓨터 시뮬레이션 방법을 제시한다. 먼저 오류회복 기능만을 고려한 다중로봇시스템에 대하여 여러 가지의 모델링 방법 중에서 확장 페트리 네트 모델을 기초로 하여 컴퓨터 시뮬레이션 하는 과정을 제시하고 제시된 시뮬레이션 방법의 유효성을 입증하기 위하여 부가적으로 큐잉모델을 기초로 한 해석적 수식을 유도하여 두 가지의 결과를 비교해 본다. 그 다음, 오류회복 기능에 덧붙여서 충돌회피 기능을 고려한 다중로봇시스템은 해석적 수식을 유도하기 위해서는 강력한 가정들이 필요하며 이러한 가정들 때문에 실제 시스템을 정확히 모델에 반영하기 어려워진다. 따라서, 그 유효성이 입증된 컴퓨터 시뮬레이션을 이용하면 필요한 최적의 운용 변수를 용이하게 선택할 수 있을 것이다. Since there are Increasing demands for multirobot interconnection systems(MRIS) in Industrial manufacturing system, the performance evaluation of the MRIS is first needed. This thesis presents a computer simulation technique for the performance evaluation of the MRIS. First, we consider a error recoverable MRIS. We adopt the extended Petri net model as a computer simulation model that allows an easy evaluation of the performance. To verify the significance of the proposed computer simulation method, mathematical analysis, which is based on the given queueing model, is carried out with some design issues for the MRIS. In addition to this, it is required to analyze the MRIS considering collision avoidance as well as error recovery. In this case, methematial analysis needs hard assumptions which are the constraints for the precise description of real environment. Thus, we present a computer simulation model and its results suggest an optimal operational strategy for the MRIS under given conditions.

• 한국정보과학회논문지:컴퓨팅의 실제 및 레터
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• 제8권3호
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• pp.336-343
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• 2002

오늘날 무선망의 출현으로 기존의 인터넷 환경은 유/무선이 통합된 단일 망으로 변화하고 있다. 그러나 현재 TCP는 전송상의 모든 패킷 손실을 혼잡으로 인한 손실로 판단하여 혼잡 윈도우를 줄이는 등의 혼잡 제어 메커니즘을 호출한다. 이것을 무선 구간에 적용시켰을 때 핸드오프나 비트 에러로 인한 패킷 손실이 발생할 때조차 혼잡으로 인한 패킷 손실로 판단하여 혼잡 윈도우를 줄이기 때문에 종단간 TCP 처리량을 저하시킨다. 본 논문에서는 이러한 문제들을 해결하기 위해 기존의 유선 망에서 혼잡 제어 메커니즘으로 사용되던 ECN(Explicit Congestion Notification)을 확장하여 무선 링크 상에서의 TCP 성능을 제어하는 기법을 제시한다. 이것은 패킷 손실이 혼잡에 의한 것인지, 무선 링크 구간에서 비트 에러 또는 핸드오프에 의한 것인지를 구분하는 기법으로 유/무선이 통합된 망에서 혼잡이 발생할 때만 혼잡 제어 메커니즘을 호출하도록 하는 기법이다.

• 자원리싸이클링
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• 제28권5호
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• pp.19-29
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• 2019

최근에 들어 태양광 발전의 시설용량이 급격히 증가되고 기 설치된 태양광 패널의 수명이 다하여 폐기될 모듈의 양이 점점 많아짐에 따라, 이에 대한 처리가 환경문제 해결뿐만 아니라 유가물질의 회수차원에서도 크나큰 관심을 받고 있다. 사용 후 태양광 모듈의 처리 공정은 대부분 알루미늄 프레임의 해체, 강화유리의 분리 회수, 실리콘 웨이퍼에 부착된 에틸렌 비닐 아세테이트(EVA)의 제거 및 태양광 셀 중에 함유된 유가금속의 회수 등으로 구성되어 있다. 전술한 태양광 폐모듈의 리싸이클링 기술들을 치밀하게 검토한 다음, 물질 선별기술을 포함한 효과적인 처리 기술을 제시하였다. 그리고 리싸이클링 산업의 활성화를 위해서 필수적인 생산자 책임제도의 시행을 비롯한 종합적인 의견을 제안하였다.

• Current Optics and Photonics
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• 제2권5호
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• pp.422-430
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• 2018

Rolling shutter operation of CMOS cameras can be utilized in optical camera communications in order to transmit data from an LED to mobile devices such as smart-phones. From temporally modulated light, a spatial flicker pattern is obtained in the captured image, and this is used for signal recovery. Due to the degradation of rolling shutter images caused by light smear, motion blur, and focus blur, the conventional decoding schemes for rolling shutter cameras based on the pattern width for 'OFF' and 'ON' cannot guarantee robust communications performance for practical uses. Aside from conventional techniques, such as polynomial fitting, histogram equalization can be used for blurry light mitigation, but it requires additional computation abilities resulting in burdens on mobile devices. This paper proposes a transition-based decoding scheme for rolling shutter cameras in order to offer simple and robust data decoding in the presence of image degradation. Based on the designed synchronization pulse and modulated data symbols according to the LED dimming level, the decoding process is conducted by observing the transition patterns of two sequential symbol pulses. For this, the extended symbol pulse caused by consecutive symbol pulses with the same level determines whether the second pulse should be included for the next bit decoding or not. The proposed method simply identifies the transition patterns of sequential symbol pulses other than the pattern width of 'OFF' and 'ON' for data decoding, and thus, it is simpler and more accurate. Experimental results ensured that the transition-based decoding scheme is robust even in the presence of blurry lights in the captured image at various dimming levels

• Annals of Rehabilitation Medicine
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• 제42권6호
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• pp.777-787
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• 2018

Objective To examine the long-term effects of the low-frequency repetitive transcranial magnetic stimulation (LF-rTMS) combined with task-specific training on paretic hand function following subacute stroke. Methods Sixteen participants were randomly selected and grouped into two: the experimental group (real LF-rTMS) and the control group (sham LF-rTMS). All the 16 participants were then taken through a 1-hour task-specific training of the paretic hand. The corticospinal excitability (motor evoke potential [MEP] amplitude) of the non-lesioned hemisphere, and the paretic hand performance (Wolf Motor Function Test total movement time [WMFT-TMT]) were evaluated at baseline, after the LF-rTMS, immediately after task-specific training, 1 and 2 weeks after the training. Results Groups comparisons showed a significant difference in the MEP after LF-rTMS and after the training. Compared to the baseline, the MEP of the experimental group significantly decreased after LF-rTMS and after the training and that effect was maintained for 2 weeks. Group comparisons showed significant difference in WMFT-TMT after the training. Only in the experimental group, the WMFT-TMT of the can lifting item significantly reduced compared to the baseline and the effect was sustained for 2 weeks. Conclusion The results of this study established that the improvement in paretic hand after task-specific training was enhanced by LF-rTMS and it persisted for at least 2 weeks.

• Journal of Yeungnam Medical Science
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• 제39권3호
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• pp.235-243
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• 2022

Background: Intrahepatic cholangiocarcinoma (ICC) of the left liver often shows left-sided lymph node (LN) metastasis. If gastric lesser curvature is extensively dissected, it can induce an iatrogenic injury to the extragastric vagus nerve branches that control motility of the pyloric sphincter and lead to gastric stasis. To cope with such LN dissection-associated gastric stasis, we performed pyloroplasty preemptively. The objective of this study was to analyze our 20-year experience of preemptive pyloroplasty performed in 10 patients. Methods: We investigated clinical sequences of 10 patients with ICC who underwent preemptive pyloroplasty following left hepatectomy and extended left-sided LN dissection. Incidence of gastric stasis and oncological survival outcomes were analyzed. Results: All 10 patients were classified as stage IIIB due to T1-3N1M0 stage according to the 8th edition of American Joint Committee on Cancer staging system. The overall patient survival rate was 51.9% at 1 year, 25.9% at 2 years, and 0% at 3 years. Seven patients showed uneventful postoperative recovery after surgery. Two patients suffered from gastric stasis, which was successfully managed with supportive care. One patient suffered from overt gastric paresis, which was successfully managed with azithromycin administration for 1 month. Conclusion: We believe that preemptive pyloroplasty is an effective surgical option to prevent gastric stasis in patients undergoing extensive left-sided LN dissection. Azithromycin appears to be a potent prokinetic agent in gastroparesis.