• Title/Summary/Keyword: Exposure model

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A study on the usefulness of a fusion model designed cloak shield to reduce the radiation exposure of the assistant during CT of severely injured patient (중증외상환자 CT 검사 시 검사보조자의 방사선피폭 경감을 위한 융합적 망토 차폐체의 유용성 연구)

  • Seo, Sun-Youl;Han, Man-Seok;Kim, Chang-Gyu;Jeon, Min-Cheol;Kim, Yong-Kyun;Kim, Gab-Jung
    • Journal of the Korea Convergence Society
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    • v.8 no.9
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    • pp.211-216
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    • 2017
  • The purpose of this study is to evaluate the usefulness of a newly fusion model designed cloak shield to reduce the radiation exposure of the assistant during CT(computed tomography) of severely injured patient. Radiation dose was measured in the heart, both axillary and thyroid areas using newly designed cloak shield and existing shield with head phantom and human phantom under the same conditions as brain vascular CT scan. The newly designed cloak shield was measured higher for radiation shielding rate than the existing shields, 61.9 % for heart, 46.2 % for left axillary, 69.8 % for right axillary and 71.1 % for thyroid gland, respectively. a newly developed fusion model of cloak shields are useful for reducing radiation exposure. It is expected to make a significant contribution to reduction of radiation exposure.

SUMRAY: R and Python Codes for Calculating Cancer Risk Due to Radiation Exposure of a Population

  • Michiya Sasaki;Kyoji Furukawa;Daiki Satoh;Kazumasa Shimada;Shin'ichi Kudo;Shunji Takagi;Shogo Takahara;Michiaki Kai
    • Journal of Radiation Protection and Research
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    • v.48 no.2
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    • pp.90-99
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    • 2023
  • Background: Quantitative risk assessments should be accompanied by uncertainty analyses of the risk models employed in the calculations. In this study, we aim to develop a computational code named SUMRAY for use in cancer risk projections from radiation exposure taking into account uncertainties. We also aim to make SUMRAY publicly available as a resource for further improvement of risk projection. Materials and Methods: SUMRAY has two versions of code written in R and Python. The risk models used in SUMRAY for all-solid-cancer mortality and incidence were those published in the Life Span Study of a cohort of the atomic bomb survivors in Hiroshima and Nagasaki. The confidence intervals associated with the evaluated risks were derived by propagating the statistical uncertainties in the risk model parameter estimates by the Monte Carlo method. Results and Discussion: SUMRAY was used to calculate the lifetime or time-integrated attributable risks of cancer under an exposure scenario (baseline rates, dose[s], age[s] at exposure, age at the end of follow-up, sex) specified by the user. The results were compared with those calculated using another well-known web-based tool, Radiation Risk Assessment Tool (RadRAT; National Institutes of Health), and showed a reasonable agreement within the estimated confidential interval. Compared with RadRAT, SUMRAY can be used for a wide range of applications, as it allows the risk projection with arbitrarily specified risk models and/or population reference data. Conclusion: The reliabilities of SUMRAY with the present risk-model parameters and their variance-covariance matrices were verified by comparing them with those of the other codes. The SUMRAY code is distributed to the public as an open-source code under the Massachusetts Institute of Technology license.

Effect of Body Exposure and Color of Suit on the Impression of Modesty (의복의 색과 신체노출이 정숙성인상에 미치는 영향)

  • Koh AeRan;Kahng Hewon
    • Journal of the Korean Society of Clothing and Textiles
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    • v.16 no.3 s.43
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    • pp.181-195
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    • 1992
  • The purposes of this study were to investigate 1) the effect of body exposure and color of a woman's suit on the perception of modesty, and 2) the effect of perceiver's sex and age on impression formed by the function of clothing variables. The instrument of this study consisted of a response scale and stimuli. Thirteen items of 7-point semantic differential scales were developed to measure the perceiver's impression on wearer's modesty. Stimuli were color pictures of a model wearing one of 8 types of suit constructed by a 2 $\times$ 2 $\times$ 2 factorial design. The manipulation of each level of the clothing variables were: color of the suit by black and red, leg exposure by varying skirt lengths to a Chanel-line and mini skirt, and neck exposure by shirt collar blouse and scarf. Two models, representing typical female college students living in Seoul, were selected to eliminate model effect. The sample include 384 subjects, consisting of 4 groups of male and female college students and middle aged men and women. Eight experimental groups were randomly assigned to one of eight stimuli based on between-subject design. One half of each group responded to model 1 and the other half to model 2 of same stimulus. Responses to the semantic differential scales were factor analyzed (pc model, Varimax rotation) to identify factors constructing impression of modesty. Two factors emerged regard­less of subgroups; Elegance and Extroversion factor. The first factor was found to be dominant, accounting for 60 percent of the total variance. The other accounted for just 11 percent. Multidimensional ANOVA (5-way, 3-way) was conducted to test the effect of the clothing variables against two factors identified from the factor analysis. Leg exposure was the most powerful variable affecting the impression of Elegance and Extroversion factor for all per. ceiver subgroups. Neck exposure had primary effect on the impression of Elegance, whereas it partially influenced that of Extroversion. Color of suit had only partial effect on the impression of Extroversion. Hypothesis I was partially supported from the findings above. The effect of perceiver's age and sex on impression by the function of clothing variables was tested by comparing the result between four subgroups. In forming an impression of the wearer's modesty, male college students were least affected by the manipulation of clothing variables, while middle aged males were affected most. In the female groups, there was no age difference and they fell between the male groups in the degree to which they were affected. Hypothesis II was supported only by age difference in two male groups, and by sex difference in two student groups.

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Acute Radiation Syndrome in an Irradiated Minipig Model for Patients with Radiation Exposure

  • Jang, Hyosun;Kim, Joong-sun;Shim, Sehwan;Jang, Won-seok;Lee, Sun-Joo;Myung, Jae Kyung;Lee, Seung-Sook;Park, Sunhoo
    • Journal of Radiation Protection and Research
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    • v.42 no.3
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    • pp.146-153
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    • 2017
  • Background: Acute radiation syndrome (ARS) primarily refers to damage to the hematopoietic system, myeloid system, and gastrointestinal (GI) system caused by radiation exposure. Such damage progresses to become life-threatening. In particular, as the syndrome develops very rapidly-within several hours from radiation exposure-prompt and accurate diagnosis and treatment are needed, as is further research into appropriate diagnostic and treatment modalities. Materials and Methods: Minipigs, which display human-like properties, underwent whole-body irradiation at 2 or 4 Gy (doses causing hematopoietic ARS) or at higher doses of 7 or 12 Gy. Changes in the blood cells and clinical symptoms were analyzed and we performed a necropsy when the animals succumbed to ARS. Results and Discussion: The minipig irradiated with 2 Gy showed a decrease in white blood cells, including neutrophils, lymphocytes, and platelets in the early stages. However, the blood cell counts gradually increased and returned to normal values. The minipig irradiated with 4 Gy succumbed due to hematopoietic ARS. In contrast, the minipigs irradiated with 7 or 12 Gy exhibited clinical symptoms of combined GI damage and hematopoietic syndrome. Moreover, a characteristic pattern of platelet changes was observed in the 7 and 12 Gy irradiated minipigs. Conclusion: The changes in the platelet count caused by radiation exposure observed in minipigs, which are hematologically and pathohistologically similar to humans, suggest that they can be used as a novel diagnostic criterion.

The effect of the exposure to hazard factors on job satisfaction in employees (임금근로자의 작업장 유해위험요인 노출이 근로환경에 대한 만족도에 미치는 영향)

  • Park, Won Yeol
    • Journal of the Korea Safety Management & Science
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    • v.16 no.3
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    • pp.257-266
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    • 2014
  • This study was planned to investigate the effect of the exposure to hazard factors on work environment satisfaction. Existing researches about job satisfaction have focused on the general working conditions, such as working hours, wage, human relationship, job task and so on. Korean Working Conditions Survey was used for this study because that relevant questions were included. The effect of the exposure to hazard factors on work environment satisfaction may be produced by hierarchical regression analysis because of comparison with existing model for work environment satisfaction. The exposure to hazards factors were statistically significant effect on work environment satisfaction after adjusting other confounding variables, such as gender, age, educational level, job security, work hour, work load, work autonomy, social support, etc. This study has some limitation because that KWCS was cross sectional survey. Some researches about the causal effect and its mechanism may be suggested as future study.

Implementation of the VHOE-based Multiview 3D Display System by using Optimized Exposure-Time Scheduling Scheme

  • Kim, Seung-Chul;Gu, Jung-Sik;Kim, Eun-Soo
    • 한국정보디스플레이학회:학술대회논문집
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    • 2002.08a
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    • pp.883-886
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    • 2002
  • A new exposure time scheduling scheme to implement the optimized photopolymer-based VHOE is proposed and using this method, the 8-view VHOE system is experimentally developed. The CGS dependence on the exposure energy is mathematically modeled using the fourth-order polynomial function and using this model optimized exposure-time schedule for recording the given multiple gratings in the photopolymer is calculated. In addition, basing on this suggested exposure-time schedule, 8-view VHOE is finally implemented and its performance is discussed.

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APPLICATION OF METABOLITE PROFILE KINETICS FOR EXPOSURE AND RISK ASSESSMENT

  • Lee, Byung-Mu
    • Proceedings of the Korean Society of Toxicology Conference
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    • 2006.11a
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    • pp.34-45
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    • 2006
  • Chemical toxicants are metabolically converted to numerous metabolites in the body. Toxicokinetic characteristics of metabolites could be therefore used as biomarker of exposure for human risk assessment. Biologically based dose response (BBDR) model was proposed for future direction of risk assessment. However, this area has not been developed well enough for human application. Benzo(a)pyrene (BP), for example, is a well-known environmental carcinogen and may produce more than 100 metabolites and BPDE-DNA adduct, a covalently bound form of DNA with benzo(a)pyrene diolepoxides (BPDES), has been applied to qualitatively or quantitaively estimate human exposure to BP. In addition, di(2-ethylhexyl) phthalate (DEHP), a widely used plasticize. in the polymer industry, is one of endocrine-disrupting chemicals (EDCs) and has been monitored in humans using urinary or serum concentrations of DEHP or its monomer MEHP for exposure and risk assessment. However, it is difficult to estimate the actual level of toxicants using these biomarkers in humans using. This presentation will discuss a methodology of exposure and risk assessment by application of metabolic profiling kinetics.

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Statistical Modeling of the Pretilt Angle Control in Nematic Liquid Crystal using In-situ Photoalignment Method on Plastic Substrate

  • Kang, Hee-Jin;Lee, Jung-Hwan;Yun, Il-Gu;Seo, Dae-Shik
    • Transactions on Electrical and Electronic Materials
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    • v.7 no.3
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    • pp.145-148
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    • 2006
  • In this study, the response surface modeling of the pretilt angle control using in-situ photoalignment method with oblique UV exposure .on plastic substrate is investigated. The pretilt angle is the main factor to determine the alignment of the liquid crystal display. The response surface model is used to analyze the variation of the pretilt angle on the various process conditions. Heating temperature and UV exposure time are considered as input factors. The liquid crystal (LC) pretilt angle increased with increasing heating temperature and UV exposure time. The analysis of variance is used to analyze the statistical significance and the effect plots are also investigated to examine the relationship between the process parameters and the response.

Numerical study on the impact response of SC walls under elevated temperatures

  • Lin Wang;Weiyi Zhao;Caiwei Liu;Qinghong Pang
    • Steel and Composite Structures
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    • v.46 no.3
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    • pp.345-352
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    • 2023
  • A thermal-mechanical coupling finite element model of the steel-plate concrete composite (SC) wall is established, taking into account the strain rate effect and variation in mechanical and thermal properties under different temperatures. Verifications of the model against previous fire test and impact test results are carried out. The impact response of the SC wall under elevated temperatures is further investigated. The influences of the fire exposure time on the impact force and displacement histories are discussed. The results show that as the fire exposure time increases, the deflection increases and the impact resistance decreases. A formula is proposed to calculate the reduction of the allowable impact energy considering the fire exposure time.

Theoretical Conception of Synergistic Interactions

  • Kim, Jin-Kyu;Vladislav G. Petin
    • Korean Journal of Environmental Biology
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    • v.20 no.4
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    • pp.277-286
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    • 2002
  • An increase in the overall biological effect under the combined action of ionizing radiation with another inactivating agent can be explained in two ways. One is the supposition that synergism may attribute to a reduced cellular capacity of damn-ge repair after the combined action. The other is the hypothesis that synergism may be related to an additional lethal or potentially lethal damage that arises from the interaction of sublesions induced by both agents. These sublesions ave considered to be in-effective when each agent is applied separately. Based on this hypothesis, a simple mathematical model was established. The model can predict the greatest value of the synergistic effect, and the dependence of synergy on the intensity of agents applied, as well. This paper deals with the model validation and the peculiarity of simultaneous action of various factors with radiation on biological systems such as bacteriophage, bacterial spores, yeast and mammalian cells. The common rules of the synergism aye as follows. (1) For any constant rate of exposure, the synergy can be observed only within a certain temperature range. The temperature range which synergistically increases the effects of radiation is shifted to the lower temperature fer thermosensitive objects. Inside this range, there is a specific temperature that maximizes the synergistic effect. (2) A decrease in the exposure rate results in a decrease of this specific temperature to achieve the greatest synergy and vice versa. For a constant temperature at which the irradiation occurs, synergy can be observed within a certain dose rate range. Inside this range an optimal intensity of the physical agent may be indicated, which maximizes the synergy. As the exposure temperature reduces, the optimal intensity decreases and vice versa. (3) The recovery rate after combined action is decelerated due to an increased number of irreversible damages. The probability of recovery is independent of the exposure temperature for yeast cells irradiated with ionizing or UV radiation. Chemical inhibitors of cell recovery act through the formation of irreversible damage but not via damaging the recovery process itself.