• Title/Summary/Keyword: Experimental surgery

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Anesthesia for the Experimental Rats (실험용 쥐의 마취)

  • Choi, Hee-Rack;Ko, Jong-Hyun;Lee, Hae Beom;Lee, Jun-Mo
    • Archives of Reconstructive Microsurgery
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    • v.22 no.1
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    • pp.1-6
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    • 2013
  • Rats and mice are commonly used in experimental laboratories and anesthetic drugs are important for researchers to understand the details. Administration of fluids helps to stabilize the experimental animals before anesthesia via intravenously through the lateral vein in rats and in case of difficulty in catheterization and maintenance, fluids are usually administered as boluses. Large volumes of cool fluids will rapidly lead to hypothermia and all parenteral fluids must be warmed to body temperature before administration. Premedication with a sedative may ease induction with volatile anesthetic drugs. The first choice for rodent anesthesia is complete inhalational anesthesia. The second option is using injectable anesthesia. Recovery from the volatile agents that have been used rapid when the agent is no longer administered. Anesthetic monitoring equipment is an infant-size bell sthethoscope that can be used to ausculate the heart and lungs. Supplemental heating should be provided to reduce the heat loss supply and maintain core body temperature. The kinds of drugs, characteristics, route of administration and care after surgery were reviewed and summarized from the references. Anesthetic drugs, maintenance, monitoring and aftercare are important in the laboratories to keep the animal safe in all experimental procedures.

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The Effect of Warming Intravenous Fluids on Body Temperature Change under a General Anesthesia, Shivering, and Recovery (수액가온요법이 전신마취 하 체온변화와 전율 및 회복에 미치는 영향)

  • Han, Hyo Jeong;Jeong, So Ra;Lee, Seong Hee;Choe, Gyeong Ran;Cha, Na Jeong;Sin, Yu Ri
    • Journal of Korean Clinical Nursing Research
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    • v.16 no.1
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    • pp.71-82
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    • 2010
  • Purpose: The study was aimed to investigate the effects of warm fluid used during surgery on the patients' hypothermia prophylaxis and recovery after surgery. Methods: This data were collected from Jul. 13 to Nov. 31. 2009 at S hospital in M City. 60 patients who met the selection criteria were recruited in the study and divided into two groups. The warmed fluids were used for 30 patients in the experimental group, and the fluids in room air temperature were used for the others in the control group. Collected data were statistically analyzed using SPSS/win 18.0. Results: The body temperatures of the control group were significantly lower during surgery than those of the experimental group (p<.001). Shivering was significantly less occurred in the experimental group than the control group (p=.018). The experimental group used warmed fluids recovered faster than the control group. Conclusion: Warming fluid for the patients with general anesthesia was revealed to be effective in decreasing hypothermia during surgery, reducing shivering, helping recovery from the anesthesia. Further research is warranted to refine and apply this evidence in nursing practice.

Comparison of Effects of Exhalation and Inhalation Breathing Exercises on Pulmonary Function and Complications in Elderly Patients with Upper-abdominal Surgery (호기 및 흡기호흡운동이 상복부 수술을 한 노인 환자의 폐환기능과 폐 합병증에 미치는 효과 비교)

  • Koo, Mijee;Hwang, Sunkyung
    • Journal of Korean Academy of Nursing
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    • v.46 no.4
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    • pp.514-522
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    • 2016
  • Purpose: The purpose of this study was to identify the effects of exhalation breathing exercises using expirometer and that of inhalation breathing exercises using incentive spirometry on pulmonary function and complications in elderly patients with upper-abdominal surgery. Methods: The research design was a nonequivalent control group non-synchronized design. Participants were 63 patients who underwent upper-abdominal surgery under general anesthesia (32 in experiment group, 31 in control group). They were recruited at P university hospital from August 1 to November 30, 2015. Effects were evaluated by measuring pulmonary functions (Forced Vital Capacity [FVC], Forced Expiratory Volume in 1 second [FEV1]) and pulmonary complications. Data were analyzed using SPSS/WIN 18.0 program. Results: There was no difference in FVC between the experimental group and the control group, but FEV1 in the experimental group increased significantly compared to the control group by time change (p=.001). Also, there were no pulmonary complications in the experimental group but there were 5 cases (16.1%)(p=.018) in the control group. Conclusion: Findings indicate that exhalation breathing exercises by elderly patients following upper-abdominal surgery is an effective nursing intervention in enhancing pulmonary function and preventing pulmonary complications.

Effect of a Therapeutic Exercise Program on the Functional Recovery Following Temporomandibular Joint Surgery (측두하악관절 수술 후 관절 운동프로그램이 기능회복에 미치는 영향)

  • Oh, Duck-Won;Kim, Ki-Song;Lee, Gyu-Wan;Jung, Nak-Su
    • Physical Therapy Korea
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    • v.6 no.3
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    • pp.94-109
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    • 1999
  • The purposes of this study were to assess the effect of therapeutic exercise and to offer an approach to the physical therapy and rehabilitation procedure of the temporomandibular joint (TMJ) following surgery. In this research, 42 patients with TMJ surgery were assigned one of two groups. The experimental group included 21 patients who performed therapeutic exercise, and the control group included 21 patients who did not perform therapeutic exercise. Conservative therapy such as an ice pack, a hot pack, and pulsed ultrasound was applied to both groups. Treatment was applied twice a day during the admission period and, after discharge, everyday for six weeks. Visual analogue scale (VAS), incisal biting force, and joint ROM were measured before surgery and at 30 days after surgery. The results were as follows: VAS (p<0.05), mouth opening (p<0.01), lateral excursion to unaffected side (p<0.05), and protrusion (p<0.05) between experimental group and control group showed statistically significant differences. Incisal biting force and lateral excursion to affected side between experimental group and control group showed no statistically significant difference.

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Comparison of the Effects of Hand Massage Provided with Different Intervals and Periods on Pain and Sleep Disturbance after Orthopedic Surgery

  • Cho, You-Na;Kim, Inja
    • The Korean Journal of Rehabilitation Nursing
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    • v.18 no.2
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    • pp.128-134
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    • 2015
  • Purpose: The purpose of this study was to compare the effects of hand massage provided with different intervals and periods on pain and sleep disturbance after orthopedic surgery. Methods: A non-equivalent control group pretest- posttest design was used. The subjects were admitted in an orthopedic hospital to get a surgery. They were divided into three groups. Group I (n=30) had hand massage every day. Group II (n=30) had hand massage every other day. Control group (n=31) had usual care. Data of all three groups were collected on the day before operation, POD (postoperative day) 6 and POD12. Hand massage was given for 2 and half minutes per hand. Results: Pain on POD6 of experimental group II was reduced more than those of control group. Pains on POD12 of both experimental groups were reduced more than those of control group. On POD6, only perceived sleep disturbance (PSD) was significantly different among groups. On POD12, PSD, total sleeping time, and sleep efficiency were more improved in the experimental groups. Conclusion: Hand massage was effective on the reduction of pain and sleep disturbance after orthopedic surgery. Applying hand massage on alternate day was effective enough. Also the effects were more obvious after 12 days.

Development of Handpiece Moving System (HMS) for Cutting Performance Evaluation of Dental Ultrasonic Surgery Unit (치과용 초음파 수술기의 절삭성능 평가를 위한 핸드피스 이송 시스템 구축)

  • Sa, Min-Woo;Shim, Hae-Ri;Ko, Tae-Jo;Lee, Jong-Min;Kim, Jong Young
    • Journal of the Korean Society for Precision Engineering
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    • v.33 no.5
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    • pp.377-383
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    • 2016
  • Recently, research on bone fracture and osteoplasty using ultrasonic bone surgery unit has been ongoing in the fields of dentistry, plastic surgery, and otorhinolaryngology. However, detailed data evaluation with ultrasonic bone surgery unit has not been conducted to date. In this study, we developed handpiece moving system (HMS) for cutting performance evaluation. In the experimental setup of HMS, a handpiece was immobilized, and bone samples from cortical bone of bovine leg were prepared. Also, the experimental process was described in detail, and a basic experiment was carried out to evaluate the cutting performance. Future study is required on all experimental process conditions by HMS.

A COMPARATIVE STUDY ON POST-OPERATIVE ANALGESIC EFFECT FOR PATIENT-CONTROLLED AND INTRAMUSCULAR ANALGESIA IN MANDIBULAR FRACTURE PATIENTS (하악골 골절환자에서 술후 자가통증조절장치와 근주용 진통제의 효과에 관한 비교)

  • Lee, Seok-Jae;Kim, Kyung-Wook;Kim, Chul-Hwan
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.28 no.1
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    • pp.42-48
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    • 2006
  • Open reduction and rigid internal fixation is the most popular treatment method for maxillofacial fracture patients, and it is unevitable that postoperative pain can be developed. Many surgeons including oral & maxillofacial surgeons have made constant efforts to decrease postoperative pain. This study is a comparison of postoperative analgesia and intramuscular analgesia in patients with mandibular fractures. In this study, twenty-one patients (Experimental group) were randomly selected and they were injected with IV patient-controlled analgesia (PCA; Walkmed$^{(R)}$, USA). For control group another twenty-one patients were injected with intramusclar non-steroid anti-inflammatory drugs (Rheoma$^{(R)}$, Samsung Pharm. Co.). And then, we measured visual analogue scale (VAS) scores from first postoperative day to second day at regular time interval. The following results were uptained; 1. In patient group who with open reduction and rigid internal fixation, there was significant difference of postoperative analgesic effect during the first postoperative day(p<0.05). 2. In patient group with over 90 minutes surgery time, there was significant difference of postoperative analgesic effect during the first and second postoperative day when compared between experimental group and control group(p<0.05). 3. In patient group with less than 90 minutes surgery time, there was no significant difference of postoperative analgesic effect during the first and second postoperative day when compared between experimental group and control group(p>0.05). 4. In patient group with surgery of open reduction using rigid internal fixation at single fractured site, there was no significant difference of postoperative analgesic effect during the first and second postoperative day when compared between experimental group and control group(p>0.05). 5. In patient group with surgery at two fractured sites, there was significant difference of postoperative analgesic effect during the first postoperative day when compared between experimental group and control group(p<0.05). As mentioned above, it suggest that patient-controlled analgesia is more effective for postoperative pain relief than intramuscular injection in patients with rigid internal fixation by open reduction after mandibular fracture occurred. Especially, it is considered that in patient with more than 90 minutes surgery time or in cases with multiple fractured sites had more effective results with PCA therapy than conventional intramuscular analgesics.

A Study on Efficacy of Preemptive Analgesia - A Comparison on Efficacy of Preoperative and Postoperative Analgesic Administration - (선행적 진통 요법의 효과성에 대한 연구 -발치 전과 후 진통 요법의 효과 비교-)

  • Jung, Young-Soo;Kim, Moon-Key;Park, Hyung-Sik;Lee, Eui-Wung;Kang, Jeong-Wan
    • Journal of The Korean Dental Society of Anesthesiology
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    • v.3 no.1 s.4
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    • pp.10-18
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    • 2003
  • Background: Studies on the pain have been dealing with many different ways for last several centuries. Especially, preemptive analgesia is being used as a method to control the postoperative pain. Many studies on its efficacy have been processed in different ways about various drugs, administration methods and times for various operations. And the value of preemptive analgesia are still controversial regarding the results of other clinical studies. The authors performed a clinical study on efficacy of preemptive analgesia using an non-steroidal anti-inflammatory drug (NSAID) for the surgical extraction of impacted third molar teeth and present the more effective pain treatment after oral surgery with literature review. Methods: Using a randomized double blind test design, this study compared the analgesic efficacies of an NSAID, Talniflumate 370 mg. This drug administrated first either 1 hour preoperatively (experimental group) or when the pain developed moderately to severely over 5 scale of verbal rating scales (0-10) to respective 30 patients undergoing the removal of impacted third molars. Pain intensity and the time from the end of surgery were assessed postoperatively whenever the patients demanded additional drug over 5 scale for forty eight hours using same verbal rating scales. Results: The sex distribution, the age of the patients. and the time required for surgery in two groups were similar. The average first time for demanding additional drug after surgery was 163.9 minutes in experimental group and 191.5 minutes in control group. At this time, the average pain intensity was 5.8 in experimental group and 6.1 in control group. And the average second time for demanding additional drug was 365.5 minutes in experimental group and 351.8 minutes in control group. At this time. the average pain intensities were 6.6 in experimental group and 6.2 in control group. No statistically significant difference was found between the average first times and second times, and the average pain intensities at first and second times in two groups. Conclusions: From these results the efficacy of preemptive analgesia used in this study was not appeared. This clinical study indicates that many NSAIDs administrated preoperatively in present practices have weak efficacy of preemptive analgesia for postoperative pain, thus the authors recommend that only postoperative analgesics are adequate without preoperative use of analgesics.

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EFFECT OF PRP (PLATELET RICH PLASMA) ON SINUS BONE GRAFTING IN RABBIT (가토의 상악동 골이식술시 혈소판 농축 혈장(Platelet Rich Plasma)의 골형성 효과)

  • Kim, Yong-Yun;Kwon, Kyung-Hwan;Choi, Moon-Ki;Oh, Sung-Hwan;Min, Seung-Ki
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.27 no.2
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    • pp.140-150
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    • 2005
  • Maxillary sinus lifting procedure and bone grafting are used to reconstruct atrophic maxillae. These procedure are usually followed by the placement of endosseous dental implants. Different materials and techniques can be used for sinus bone grafting. Platelets are known to contain various growth factors involved in the repair of the vasculature and tissues, and it is known that the specialized platelet secretory granules, the alpha granules, contain platelet derived growth factor(PDGF), transforming growth factor-beta(TGF-beta), insuline like growth factor-I(IGF-I), epidermoid growth factor(EGF), and others. This study was to evaluate the effect of PRP on bone formation in a sinus bone grafting. Twelve rabbits were included in this randomized, blinded, prospective pilot study. In experimental group, sinus bone grafting with autobone and platelet rich plasma. In control group, sinus bone grafting with only autobone. Rabbits were sacrificed at 2nd, 4th, 8th, 12th weeks postoperatively. Clinical and radiographic tests, histological analysis were conducted to compare both sides. In clinical examination, there in no significant difference between experimental group and control group. But, in radiographic examination, a distinct incresed in the radiopaque of the PRP experimental group at 2nd and 4th weeks. The histologic examination revealed that more new bone formation and osteoblast activity were seen in experimental group at 2nd and 4th weeks. In conclusion, PRPs action in sinus bone grafting had a capacity of increased new bone formation in a early bone healing stage.

The Effect of Music Therapy on Anxiety of Cesarean Section Wemen (음악요법이 제왕절개 임부의 수술불안에 미치는 영향)

  • Kwun Young-Sook;Kim Tae-Hee
    • Journal of Korean Academy of Fundamentals of Nursing
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    • v.7 no.3
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    • pp.466-478
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    • 2000
  • The purpose of this study was to identify the effects of music therapy on anxiety of cesarean section wemen. The research design was a nonequivalent control group non-synchronized design. The subjects of this study were 65 cesarean section wemen scheduled for surgery. The study was conducted from October 15, 1999 to January 5, 2000. Two groups consisted of subjects assigned : one the experimental group(33 wemen), and the other the control group(32 wemen). The music therapy was performed 3 times to experimental group just before surgery day, on surgery day. The level of anxiety was measured by State Anxiety Inventory, blood pressure, pulse rate, respiratory rate. The data were analyzed using descriptive statistics, $x^2-test$, t-test, Repeated measures of ANCOVA. The results of study were as fellows : 1) State anxiety scores were significantly different between the experimental group and the control group after music therapy. 2) Systolic blood pressures and diastolic blood pressures were significantly different between the experimental group and the control group after music therapy. 3) Pulse rates were significantly different between the experimental group and the control group after music therapy. 4) Respiratory rates were significantly different between the experimental group and the control group after music therapy. According to these results, music therapy can be regarded as an effective nursing intervention that relieves anxiety of cesarean section wemen.

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