• Macromolecular Research
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• 제10권2호
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• pp.115-121
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• 2002

Synthesis of polymers with controlled thermosensitive properties was carried out by conventional radical copolymerization of N-isopropylacrylamide (NIPAAm) with N-vinylpyrrolidone (NVP) taken as a hydrophilic comonomer. Lower activity of NVP rather than NIPAAm was revealed by gravimetric and $^1$H NMR analysis. Thermosensitive properties of the copolymers were investigated. It was found that aqueous solutions of the copolymers undergo thermo-induced phase transition and become opaque, precipitate or gel with heating. After formation of the gels their significant contraction was observed at storage. Swelling degree and amount of expelled water were measured in dependence on the copolymer composition, temperature and ionic strength of environment medium and concentration of the solution. It was determined that in collapsed state gels exhibit quite high water content. According to physico-chemical properties of the copolymers observed they could be suitable for biomedical application as an injectable implant material.

• 한국축산식품학회지
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• 제36권4호
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• pp.487-493
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• 2016

The antimicrobial activity of bovine lactoferrin hydrolysates (bLFH) was measured against Pseudomonas strains (P. syringae and P. fluorescens) in vitro. To compare susceptibility to bLFH, minimal inhibitory concentration (MIC) values were determined using chemiluminescence assays and paper disc plate assays. Antimicrobial effect against P. fluorescens was not observed by either assay, suggesting that bLFH did not exhibit antimicrobial activity against P. fluorescens. However, a significant inhibition of P. syringae growth was observed in the presence of bLFH. The addition of bLFH in liquid or solid medium inhibited growth of P. syringae in a dose-dependent manner. Furthermore, a bLFH peptide with antimicrobial activity toward P. syringae was isolated and identified. The N-terminal amino acid sequences of thus obtained antimicrobial bLFH peptides were analyzed by a protein sequencer and were found to be Leu-Arg-Ile-Pro-Ser-Lys-Val-Asp-Ser-Ala and Phe-Lys-Cys-Arg-Arg-Trp-Gln-Trp-Arg-Met. The latter peptide sequence is known to be characteristic of lactoferricin. Therefore, in the present study, we identified a new antimicrobial peptide against P. syringae, present within the N-terminus and possessing the amino acid sequence of Leu-Arg-Ile-Pro-Ser-Lys-Val-Asp-Ser-Ala.

• Asian-Australasian Journal of Animal Sciences
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• 제15권11호
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• pp.1559-1563
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• 2002

The ovarian follicular fluid was found to contain steroidogenesis stimulatory protein similar to albumin from human and buffalo. Therefore, the albumins from various species, commercial and purified, were studied for their steroidogenic effect on progesterone secretion by granulosa cells from buffalo ovaries, during culture. A dose of $20{\mu}g$ of bovine serum albumin was optimum to exhibit maximum progesterone secretion on day 6 of culture, in medium ($350{\mu}l$) containing $10^5$ cells. Among commercial albumins, chicken albumin showed highest effect on progesterone secretion, which was followed by albumins from goat, bovine, human, sheep and rat, respectively at day 6 of culture. The albumins were also purified from blood serum of buffalo, goat and rat using salt fractionation, ion-exchange chromatography, gel filtration and SDS-PAGE. The highest stimulatory effect on progesterone secretion was shown by albumin purified from buffalo blood serum and lowest by that from rat blood. Comparatively the buffalo and goat albumins were more biologically active than commercial albumins. The presence of some active molecules conjugated with freshly purified albumins may be responsible for better stimulatory effect.

• 국제초고층학회논문집
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• 제5권4호
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• pp.271-291
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• 2016

There is much architectural and engineering literature which discusses the virtues of exterior bracing and diagrid systems in regards to sustainability - two systems which generally reduce building materials, enhance structural performance, and decrease overall construction cost. By surveying past, present as well as possible future towers, this paper examines another attribute of these structural systems - the blend of structural functionality and aesthetics. Given the external nature of these structural systems, diagrids and exterior bracings can visually communicate the inherent structural logic of a building while also serving as a medium for artistic effect. Viewed in this light, the visual appeal of these systems can be enhanced to give a tower a more distinct urban identity. This entails the creation of structural elements that are aesthetically pleasing, geometrically coherent and that demonstrate dexterity of application in regards to a building's composition, while also respecting the laws of physics and mechanics. In this fashion, an artistic approach can exhibit structural systems as not just purely rational features that enable the construction of tall buildings, but as important visual components that afford opportunities for creative expression. This paper, therefore, synthesizes the concepts of structural performance and creative artistry to facilitate a better understanding of the aesthetic developments in skyscrapers worldwide.

• 자연과학논문집
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• 제13권1호
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• pp.35-50
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• 2003

점토광물은 첨단소재용 원료로서 석유, 펄프, 비료, 점결제와 페인트 등 사용분야가 다양한 광물이며, 이러한 천연 점토광물을 비교적 간단하게 처리하여 체내에 농축되면 독성과 피해를 일으키는 염료 폐수의 흡착처리 및 흡착 메커니즘에 대해서 조사하였다. 그 결과 유기염료를 흡착처리하기 위한 입상 점토광물제조의 최적조선은 굽기온도 $700^{\circ}C$이며, 점결제인 polyvinyl alcohol 의 량은 25% 이었다. 제조된 입상 점토광물의 pH는 중성이었고 산성 메디움에서의 안정한 pH의 범위는 3~9 사이였고, 비표면적은 $83m^2/g$ 이였다. 제조된 입상점토광물에 대한 유기염료의 흡착량은 산성 메디움에서 좋은 흡착결과를 보였고, 이때 흡착엔탈피는 -3.36~ -0.84 kcal/mol 로 전형적인 물리흡착임을 나타내었다.

• Mycobiology
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• 제36권4호
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• pp.260-265
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• 2008

Cyclic voltammetric measurements were performed for Co(II), Ni(II), Cu(II) and Zn(II) complexes of 1 : 1 alternating copolymer, poly(3-nitrobenzylidene-1-naphthylamine-co-succinic anhydride) (L) and Ni(II) and Cu(II) complexes of 1 : 1 alternating copolymer, poly(3-nitrobenzylidene-1-naphthylamine-co-methacrylic acid) ($L^1$). The in vitro biological screening effects of the investigated compounds were tested against the fungal species including Aspergillus niger, Rhizopus stolonifer, Aspergillus flavus, Rhizoctonia bataicola and Candida albicans and bacterial species including Staphylococcus aureus, Escherichia coli, Klebsiella pneumaniae, Proteus vulgaris and Pseudomonas aeruginosa by well diffusion method. A comparative study of inhibition values of the copolymers and their complexes indicates that the complexes exhibit higher antimicrobial activity. Copper ions are proven to be essential for the growth-inhibitor effect. The extent of inhibition appeared to be strongly dependent on the initial cell density and on the growth medium. The nuclease activity of the above metal complexes were assessed by gel electrophoresis assay and the results show that the copper complexes can cleave pUC18 DNA effectively in presence of hydrogen peroxide compared to other metal complexes. The degradation experiments using Rhodamine B dye indicate that the hydroxyl radical species are involved in the DNA cleavage reactions.

• 한국응용약물학회:학술대회논문집
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• 한국응용약물학회 1998년도 Proceedings of UNESCO-internetwork Cooperative Regional Seminar and Workshop on Bioassay Guided Isolation of Bioactive Substances from Natural Products and Microbial Products
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• pp.135-135
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• 1998

To find an antagonist of Pythium ultimum, the causal agent of damping-off, numerous actinomycete strains were screened for in vitro inhibiting mycelial growth of the target fungus and producing bioactive metabolites. A strain identified as Streptomyces sp. G60655 was isolated and used for further antagonistic efficacy. The degree of antagonism between the fungus and G60655 was affected by the medium used. Furthermore, the preinoculation of the antagonist was found to be necessary to exhibit the maximum efficacy of antagonsim against the fungus. From the culture broth, a bioactive metabolite was detected and purified by solvent extraction, silica gel chromatography and preparative HPLC. The FAB-MS spectrum of the active compound showed a molecular ion peak at m/z 1101 (M + H)$\^$+/, suggesting the molecular weight of 1100. The UV absorptions at 242 and 323 nm indicated the presence of aromatic functions. The structure of this compound was identified as echinomycin, a depsipeptide antibiotic by spectroscopic studies including various NMR measurements. Echinomycin was inactive against several soil born fungi, but inhibited the mycelial growth of P. ultimum and its related oomycetous fungi.

• Advances in Computational Design
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• 제1권2호
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• pp.139-154
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• 2016

The usage of sandwich structure is extensively increasing in lightweight protective structures due to its low density and other useful properties. Sandwich panels made of metal sheets with unfilled cellular cores are found to exhibit lower deflections by comparing to an equivalent monolithic plate of same metal and similar mass per unit density. However, the process of localized impact on solid structures involving plastic deformation, high strain rates, temperature effect, material erosion, etc. does not hold effectively as that of monolithic plate. In present work, the applications of the sandwich plate with corrugated core have been extended to develop optimized lightweight armour using foam as medium of its core by explicit finite element analysis (FEA). The mechanisms of hardened steel projectile penetration of aluminum corrugated sandwich panels filled with foams have been numerically investigated by finite element analysis (FEA). A comparative study is done for the triangular corrugated sandwich plate filled with polymeric foam and metallic foam with different densities in order to achieve the optimum penetration resistance to ballistic impact. Corrugated sandwich plates filled with metallic foams are found to be superior when compared to the polymeric one. The optimized results are then compared with that of equivalent solid and unfilled cores structure to observe the effectiveness of foam-filled corrugated sandwich plate which provides an effective resistance to ballistic response. The novel structure can be the alternative to solid aluminum plate in the applications of light weight protection system.

• 천문학회보
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• 제38권1호
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• pp.31.2-31.2
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• 2013

We use grid-based hydrodynamic simulations to study star formation in nuclear rings in barred galaxies. The gaseous medium is assumed to be infinitesimally thin, isothermal, and unmagnetized. To investigate various situations, we vary the total gas content in the bar regions and the bar growth time. We find that star formation rate (SFR) in a nuclear ring is determined by the mass inflow rate to the ring rather than the total gas mass in the ring. The SFR shows a strong primary burst and weak secondary bursts at early time, and declines to small values at late time. The primary burst is caused by the rapid gas infall to the ring due to the bar growth, with its duration and peak depending on the bar growth time. The secondary bursts result from re-infall of the ejected gas by star formation feedback of the primary burst. When the SFR is low, ages of young star clusters exhibit an azimuthal gradient along the ring since star formation takes place mostly near the contact points between the dust lanes and the nuclear ring. When the SFR is large, on the other hand, star formation is widely distributed throughout the whole length of the ring, with no apparent age gradient of star clusters. Regardless of SFR, star clusters have a positive radial age gradient, with younger clusters located closer to the ring, since the ring shrinks in size over time.

• 한국기계가공학회지
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• 제11권6호
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• pp.169-174
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• 2012

Electromagnetic interference(EMI) shielding effectiveness(SE) was investigated in of woven fabric made of epoxy/copper-nickel fabrics and nickel coated carbon fiber reinforced acrylonitrile-butadiene-styrene(ABS) composites. The coaxial transmission line method was used to measure the EMI shielding effectiveness of the composites. We designed and constructed a measuring system, consisting of a network analyzer and a device that plays the serves as a sample holder and at the same time as a transmission medium of the incident electromagnetic wave. The measurement of SE were carried out frequency range from 100MHz to 2GHz. It is observed that the SE of the composits is the frequency dependent increase with the increase in nickel coated carbon fibre volume fraction. The nickel coating with 20wt% ABS composite was shown to exhibit up to 60dB of SE. The result that nickel coated carbon fibre ABS composite can be used for the purpose of EMI shielding as well as for some microwave applications.