• 운동과학
• /
• 제21권1호
• /
• pp.111-120
• /
• 2012

본 연구는 복부비만 여성을 대상으로 운동 트레이닝을 통해 심폐체력의 반응의 차이가 심혈관계 위험요인 및 아디포싸이토카인 분비 및 유전자 발현에 미치는 영향을 알아보는 데 그 목적이 있다. 본 연구는 운동 트레이닝 실시 후 심폐체력 향상의 유무를 이용하여 복부비만 여성 총 48명을 운동-반응 집단(n=34)과 운동-비반응 집단(n=14)으로 나누었다. 운동 트레이닝은 주당 1200kcal를 소모하도록 설계되었으며, 중등도-활발한 운동강도, 걷기나 간단한 조깅의 형태로 12주간 실시하였다. 측정 변인으로 실험 참가 전, 후에 신체조성, 혈압, 심폐체력, 혈중지질, 글루코스, 인슐린 그리고 유리지방산을 측정하였으며, 혈중 아디포싸이토카인과 복부지방 아디포싸이토카인 유전자 발현을 분석하였다. 본 연구의 결과 운동 트레이닝 후 두 집단 모두 비만지표에서 통계적으로 유의하게 감소하였지만, 허리둘레(p=0.040), 체지방률(p=0.031) 그리고 중성지방(p=0.023)과 수축기 혈압(0.046)은 운동-반응 집단과 운동-비반응 집단에서 상호작용 효과를 보였다. 혈중 렙틴은 두 집단에서 상호작용 효과(p=0.022)가 나타났으나 복부지방 렙틴 유전자는 두 집단 모두에서 트레이닝 후(p<0.001)에 유의하게 감소하였다. 이상의 결과를 종합해보면 12주간 운동 트레이닝 실시 후 심폐체력의 향상을 보인 운동-반응 집단은 운동-비반응 집단에 비해 심혈관계 질환 위험요소와 아디포싸이토카인 분비 및 유전자 발현에 더 효과적인 것으로 나타났다. 또한 운동 트레이닝 실시 후 심폐체력의 개선이 없었던 운동-비반응 집단에서도 비만지표와 혈중 렙틴 및 렙틴 유전자 발현이 감소되는 것을 살펴봤을 때 규칙적인 운동 자체가 비록 심폐체력의 개선이 없더라도 인간의 건강상의 이점을 주는 것으로 나타났다. 따라서 심폐체력이 향상되지 않더라도 규칙적인 운동 은 비만 관련 위험요인의 감소 및 예방에 좋은 영향을 주는 것으로 사료된다.

• 운동과학
• /
• 제21권3호
• /
• pp.373-384
• /
• 2012

흡기근 훈련을 동반한 유산소운동이 흡기근력, 폐기능, 최대산소섭취량(maximal oxygen uptake; VO₂max)에 어떠한 영향을 미치는지 연구하였다. 24명의 건강한 대학생이 3 그룹으로 나뉘어 6주간의 실험에 참여하였다. 대상자들은 호흡근육훈련(RTG; n=8), 유산소성달리기훈련(REG; n=8), 호흡근육 및 달리기훈련(BTG; n=8) 그룹으로 나뉘었다. 실험전과 후 폐기능, 최대흡기압력(maximal inspiratory pressure; PImax), VO₂max가 평가되었다. RTG는 실험기간 동안 흡기근육훈련(inspiratory muscle training; IMT) 프로그램에 참여하였으며, PImax 의 50 % 강도로, 하루 2회, 주당 4일, 회당 30회 훈련하였다. REG는 개인별 VO₂max의 70-75 % 강도로, 하루 1회, 주당 4회, 회당 30분 달리기 훈련을 하였다. BTG는 같은 기간 동안 IMT와 달리기훈련 모두에 참여하였다. 실험기간 중 대상자들의 체격변인과 폐기능 변인은 변하지 않았다. VO₂max는 RTG, REG, BTG에서 각각 6.1±3.3 %, 5.9±6.6 %, 10.0±8.3 % 증가하였고(p< .05), PImax 또한 RTG, REG, BTG에서 각각 21.7±14.3 %, 19.7±12.0 %, 27.0±12.1 % 증가하였으나(p< .05), 그룹 간의 유의한 차이는 나타나지 않았다. 결론적으로, 모든 그룹에서 향상이 관찰되었으며, 흡기근 훈련과 유산소운동을 동반한 그룹에서 VO₂max와 PImax의 가장 큰 향상을 보였다.

• 한국산학기술학회논문지
• /
• 제22권1호
• /
• pp.363-371
• /
• 2021

본 연구는 12주간 복합운동 중 혈류제한을 적용한 것과 적용하지 않은 것이 65세 이상 여성노인들의 운동수행능력(심폐지구력, 하체근력)과 평형성(동적평형성, 낙상위험지수)에 미치는 영향을 알아보기 위해 실시하였다. 연구대상자는 혈류제한을 통한 복합운동(14명), 혈류제한을 하지 않은 복합운동(14명)과 통제집단(15명)으로 총 43명이 연구에 참여하였다. 혈류제한 복합운동 그룹과 복합운동 그룹 모두 주 3회 총 12주 동안 복합운동을 실시하였고, 통제집단은 훈련기간 동안 일상적인 생활을 하였다. 본 연구의 자료처리는 SPSS/ver22를 사용하였으며 사전값의 동질성 검사 후 이원반복측정분산분석(Two-way Repeated Measures ANOVA)과 대비검증(contrast)을 이용하여 분석하였고, 모든 자료의 유의수준은 α=.05로 설정하였다. 연구결과 혈류제한을 적용한 복합운동 집단과 적용하지 않은 복합운동 집단의 운동수행능력(심폐지구력, 하체근력)과 평형성(동적평형성)은 유의하게 증가하였고, 두 집단 모두 낙상위험지수는 유의하게 감소하였다. 하지만 통제집단에서는 유의한 변화가 없었다. 추가적으로 두 운동집단 중 혈류제한을 적용한 복합운동 집단이 사전과 사후 변화량(%△)과 효과크기(effect size)가 일반복합운동 집단 보다 높이 나왔다. 이는 혈류제한을 적용한 복합운동집단이 혈류제한을 적용하지 않은 복합운동보다 운동수행력과 평형성에 더욱 긍정적인 효과를 나타냈다.

• 대한통합의학회지
• /
• 제8권4호
• /
• pp.133-142
• /
• 2020

Purpose : The purpose of this study was to investigate the effective recovery method of exercise-induced fatigue and muscle pain by comparing the effect of the use of illite hot mat product and general hot mat product on the recovery of muscle pain induced by high intensity exercise. Methods : To measure and analyze the changes in lactic acid, CRP, and ACR according to the high-intensity circuit training program, this study was conducted for the healthy adult men and women, who exercise st the K-region sports center. A total of 45 subjects were studied in 15 groups of 15 patients who received an illite hot-water mat recovery group (A group), 15 general hot-water mat recovery group (B group), and 15 control group (C group). The circuit training exercise program was conducted as a one-time exercise, and each exercise time consisted of 30 minutes of warm-up exercise, 5 minutes of main exercise, 20 minutes of clean-up exercise, and 5 minutes of strength exercise. The intensity setting was high intensity of subjective exercise intensity It carried out by setting to (14-16RPE). Results : Changes in Lactic Acid Concentration There was a significant difference in the lactic acid concentrations between the groups after the high intensity circuit training program (p <.05). The illite rest group (A) decreased 7.71 mmol / L and the control group decreased 4.03 mmol / L. Significantly decreased (p <.05). Changes in ACR Concentration. There was a significant difference in the ACR concentrations Significant differences were found in CRP and ACR during the recovery period after exercise. (p <.05), the elite rest group (A) decreased 2.47 mg / mmol, and the control group increased 1.63 mg / mmol. There was a significant difference (p <.05). Conclusion: The static rest on a heated mat after high-intensity exercise has an effect on changes in blood lactate and ACR levels.

• 대한간호학회지
• /
• 제33권5호
• /
• pp.591-600
• /
• 2003

Purpose: The purpose of this study was to investigate the effects of exercise training using biofeedback and constraint-induced movement on the upper extremity function of hemiplegic patients. Method: A non-equivalent pretest-posttest design was used. Study subjects were a conveniently selected group of 40 hemiplegic patients(20 experimental subjects, 20 control subjects) who have been enrolled in two community health centers. After biofeedback training the subjects of experimental group were given constraint-induced movement, involving restraint of unaffected U/E in a sling for about 6 hours in a day over a period of two weeks, while at the same time intensively training the affected U/E. Outcomes were evaluated on the basis of the VIE motor ability(hand function, grip power, pinch power, U/E ROMs), and motor activity(amount, quality). Result: 1. After 2 weeks of treatment, the motor abilities of affected U/E(hand function, grip power, pinch power, ROMs of wrist flexion, elbow flexion and shoulder flexion/extension) were significantly higher in subjects who participated in exercise training than in subjects in the control group with no decrement at 4-week follow-up. However, there was no significant difference in wrist extension between experimental or control group. 2. After 2 weeks of treatment, the amount of use and the quality of motor activity of affected U/E were significantly higher in subjects who participated in exercise training than in subjects in the control group with no decrement at 4-week follow-up. Conclusion: The above results state that exercise training using biofeedback and constraint-induced movement could be an effective intervention for improving U/E function of chronic hemiplegic patients. Long-term studies are needed to determine the lasting effects of constraint-induced movement.

• 생명과학회지
• /
• 제22권5호
• /
• pp.569-574
• /
• 2012

본 연구는 운동 트레이닝이 비만 어린이의 산화적 스트레스, 신경성장 및 간 세포성장 인자에 미치는 영향을 알아보기 위하여 12주간 유산소 운동을 실시한 후 트레이닝 전과 후의 농도 수준을 비교하였다. 연구결과, NGF와 BDNF는 트레이닝 전과 후 모두 OT군이 NT군 보다 낮았으며, NGF는 트레이닝에 따라 두 그룹 모두 증가되었다. HGF는 트레이닝 전 OT군이 NT군 보다 높게 나타났지만, 트레이닝 후 차이는 없었다. MDA, ox-LDL, 8-OHdG 모두 OT군이 NT군 보다 높은 수치를 나타냈고, 트레이닝에 따른 차이는 ox-LDL에서만 발견되었다. 이상의 결과, 비만은 성장기 어린이에게 산화적 스트레스를 유발하고, 신경과 간 성장인자의 분비 이상을 초래한다는 것을 알 수 있었고, 12주 유산소 운동은 이들 인자들의 개선에 긍정적인 영향을 주고 인지기능 향상에도 도움을 줄 수 있을 것으로 본다.

• Asian Pacific Journal of Cancer Prevention
• /
• 제14권5호
• /
• pp.2931-2936
• /
• 2013

Background: Doxorubicin is an anthracycline antibiotic commonly used to treat a variety of cancers as a most effective antitumor. However, its clinical use is associated with the toxic effects in numerous healthy tissues. Here we investigated the pretreatment effect of regular aerobic exercise on oxidative stress in rats acutely exposed to DOX-induced hepatotoxicity. Materials and Methods: Forty-eight Wistar male rats were randomly divided into 2 groups: control and training. The training protocol included treadmill running between 25 to 54 min/day and 15 to 20m/min, 5 days/week for 6 weeks. At the end of the exercise training protocol, rats from the control and trained groups were again randomly separated into 3 subgroups: DOX10mg/kg, DOX20mg/kg and saline. All treatments were carried 24 h after the last exercise bout and animals were sacrificed 24 h after DOX and saline injections. Results: Administration of DOX (10 and 20 $mg.kg^{-1}$) resulted in imbalance in biomarkers related to oxidants and antioxidants in liver tissue, as compared to control groups. Six weeks of pretreatment training led to a significant increase in nitric oxide (NO), superoxide dismutase (SOD) and glutathione peroxidase (GPX) as compared to the control+DOX 10 mg/kg group. Training before DOX 20 mg/kg administration also led to a significant increase in NO and SOD, and a significant decrease in malondialdehyde (MDA). In addition, there was a significant difference between DOX 10 mg/kg and DOX 20 mg/kg treatments in MDA levels, only. Conclusions: The results of the present study indicate that pretreatment with aerobic exercise induces positive adaptations and has a potential protective effect against doxorubicin (DOX)-induced hepatotoxicity with doses of 10 and 20 mg.kg.

• 재활간호학회지
• /
• 제5권2호
• /
• pp.134-144
• /
• 2002

Purpose: The purpose of this study was to investigate the effects of upper extremity exercise training on the motor activity, the ADL and the health related quality of life. Method: A non-equivalent pretest-posttest design was used. Study subjects were conveniently selected 40 hemiplegic patients(20 experimental subjects, 20 control subjects) who had been enrolled in two community health centers. After biofeedback training the subjects of experimental group were given constraint-induced movement, involving restraint of unaffected U/E in a sling for about 6 hours over a period of two weeks, while at the same time intensively training the affected U/E. Outcomes were evaluated on the basis of motor activity(amount, quality) of plegic side, ADL(ADL, IADL) and health related QOL(SF-36). Results: 1. After 2 weeks of treatment, the amount of use and the quality of motor activity of affected U/E were significantly higher in subjects who participated in exercise training than in subjects in the control group. 2. There were no significant differences in ADL and IADL between experimental and control groups. 3. After 2 weeks of treatment, the health related QOL was significantly higher in subjects who participated in exercise training than in subjects in the control group. Conclusion: The above results state that the U/E exercise training could be an effective intervention for improving the motor activity and the health related QOL of chronic hemiplegic patients. Long-term studies are needed to determine the lasting effects of constraint-induced movement.

• The Journal of Korean Physical Therapy
• /
• 제29권4호
• /
• pp.201-206
• /
• 2017

Purpose: The aim of this study was to identify the effects of Pilates mat exercise may improve trunk muscle thickness and balance in healthy adults. Methods: Eighteen healthy adults participated in this study. They were randomly assigned to one of two groups: Pilates mat exercise group (n=9) and the control group (n=9). Subjects in Pilates mat exercise group performed the exercises three days per week for 6 weeks, which consisted of warm up, main workout, and cool down. Trunk muscle thickness of the rectus abdominis (RA), internal oblique (IO), external oblique (EO), transverse abdominis (TrA), multifidus (MF), and erector spine (ES) were measured using an ultrasonography. Balance ability was evaluated using Romberg test and limits of stability (LOS). Measurements were performed before training, 3 weeks after training, and 6 weeks after training. Results: There was a significant difference of RA, EO, IO, MF, and ES according to the main effect of time (p<0.05). There was a significant difference of EO, MF, ES, Romberg, and LOS according to interaction effect between the time and group (p<0.05). There was a significant difference only for LOS according to the main effect of the group (p<0.05). Conclusion: Pilates mat exercise did increase trunk muscle thickness and balance. However, the effect with respect to trunk thickness was limited. Pilates mat exercise appears to be more effective in improving muscles related to trunk extension and balance.

• Preventive Nutrition and Food Science
• /
• 제3권1호
• /
• pp.71-76
• /
• 1998

This study investigated the effect of regular exercise on serum lipid profiles and carnitine levels in college students. Daily nutrient intake, anthropometry , serum lipid, and carnitine profiles in serum and urine were evaluated prior to beginning the study and after 35 days of treadmill running for 30 minutes per day. The results obtained were summarized as follows : 1) Concentrations of total lipid and Triglyceride in serum were decreased by regular exercise in female subjects but unaffected in males. 2) Serum LDL-cholesterol was significantly decreased, but total cholesterol and HDL-cholesterol in serum were not affected in both male and female subjects. 3) nonesterified carnitinem, acid-insoluble acylcarnitine, and total carnitine levels in serum were not affected, but acid-soluble acylcarnitine level was increased by regular exercise in both subjects. 4) Urinary excretionof the acid-soluble acylcarnitine level was increased by regular exercise -training. These results suggest that regular exercise -training has different effects on serum lipid oxidation via carnitine metabolism in this condition.