• Korean Journal of Pharmacognosy
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• v.27 no.2
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• pp.155-158
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• 1996

The methanol extract of Albizzia julibrissin Durazz. (Leguminosae) was successively partitioned into dichloromethane, ethylacetate, butanol (BuOH) and water fractions, and the effects of the each solvent extract on catecholamine biosynthesis in PC12 cells were investigated. Among them, the BuOH fraction $(5{\mu}g/ml\;medium)$ showed 68.8% and 63.6% inhibition on dopamine and norepinephrine content in PC12 cells, respectively. Tyrosine hydroxylase (TH) activity was also reduced markedly by treatment of the BuOH fraction (41.8% inhibition at $5{\mu}g/ml$ in the medium). Each solvent fraction did not show cytotoxicity towards PC12 cells by trypan blue exclusion test. This result suggests that the BuOH fraction has an inhibitory effect on catecholamine biosynthesis by reducing TH activity in PC12 cells.

• Proceedings of the KSRS Conference
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• 2003.11a
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• pp.773-775
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• 2003

From the view point of data fusion, we integrate LIDAR data and digital aerial images to perform 3D building modeling in this study. The proposed scheme comprises two major parts: (1) building block extraction and (2) building model reconstruction. In the first step, height differences are analyzed to detect the above ground areas. Color analysis is then performed for the exclusion of tree areas. Potential building blocks are selected first followed by the refinement of building areas. In the second step, through edge detection and extracting the height information from LIDAR data, accurate 3D edges in object space is calculated. The accurate 3D edges are combined with the already developed SMS method for building modeling. LIDAR data acquired by Leica ALS 40 in Hsin-Chu Science-based Industrial Park of north Taiwan will be used in the test.

• Culinary science and hospitality research
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• v.23 no.5
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• pp.48-57
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• 2017

This study aims to analyze the relationships among brand value, brand trust, and brand loyalty of dessert cafes and to verify the mediating effect of brand trust in the relationship between brand value and loyalty. This study targeted eight dessert cafes located in Seoul, and a survey with customers aged 20 or over was conducted over 11 days from April 10th to 21th, 2017. A total of 230 self-administered questionnaires were distributed, and 205 questionnaires (89.13%) were included for the data analysis after the exclusion of 25 incomplete and unreliable responses. Every data used for analysis went through frequency analysis, reliability test, exploratory factor analysis, simple regression analysis, multiple regression analysis, mediator effect analysis, and Sobel test using the SPSS 18.0 analysis program. The study results revealed that brand value had a significant positive relationship to brand trust, and brand trust had a significant positive relationship to brand loyalty. Also, brand value had a significant positive relationship to brand loyalty, and brand trust mediated the relationship between brand value and loyalty. Based on these findings, the discussion to enhance brand loyalty of dessert cafes were suggested.

• Journal of Families and Better Life
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• v.25 no.1 s.85
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• pp.159-167
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• 2007

The purpose of this study was to investigate the evaluation of regional antagonism in children and adolescents in Youngnam and Honam region. There were 684 subjects included in this study from three ages in the Youngnam and Honam regions: 12.8 years(6th grade, n=208), 14.8 years(8th grade, n=211), and 16.9 years(10th grade, n=265). Of the 684 subject, 357(53.3%) were boys and 327(47.8%) were girls. The instruments consisted of subjects' self-reported social distance, stereotype, and prejudice. The data were analyzed by frequencies, t-test, one-way ANOVA and the $Scheff\'{e}$ test. Major findings were as follows: The mean score of the out-group stereotype was greater than the median, so the in-group preference was greater than the out-group exclusion. The in-group stereotype was different based on the age and the sex. The 6th and 8th graders and the boys were higher than 10th and the girls. The prejudice was different based on the lesion. The social distance was different based on the age and the region.

• Journal of the Korean Society of School Health
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• v.36 no.2
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• pp.52-61
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• 2023

Purpose: The purpose of the study was to compare the characteristics between adolescents who have run away from home before and who have contemplated running away from home before, and to find risk factors that predict runaway behavior among them. Methods: The data of 「the survey on adolescents' right to adequate housing and the way to ensure their housing with the focus on social exclusion」 by the National Youth Policy Institute (2020) were analyzed. A total of 494 adolescents were included in the study. Descriptive statistics, x2 test, t-test, and simple and multiple logistic regressions were carried out using SAS 9.2. Results: Gender, depression, anxiety, self-esteem, and school level were significantly different between the two groups. From the multivariate analysis, the adjusted odds ratio for runaway behavior was significantly higher in male students (AOR: 2.14, p<.001), lower in the middle economic class than in the high economic class (AOR: 0.64, p=.051), lower in the 4th quartile group of self-esteem (AOR: 0.52, p=.041), and higher in high school students (AOR: 1.55, p=.050). Conclusion: Considering that male students, students from wealthier families, students with low self-esteem, and high school students are high-risk groups for runaway behavior, among adolescents who have contemplated running away before, interventions targeting these groups are needed.

• The Journal of Internal Korean Medicine
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• v.27 no.2
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• pp.379-393
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• 2006

Objectives: We are aimed to identify anti-tumor effects of Curcuma aromatics on some kinds of cancer cells through molecular biologic methods. Materials & Methods: We used 4 kinds of cancer cell lines such as lung cancer cells(AS49), cervical cancer cells(HeLa), glioma cancer cells(A172) and prostate cancer cells(PC3). We treated the boiled extract of Curcuma aromatica $5{\mu}g,\;10{\mu}g$ to cultural media(ml) for 24 hours. We measured the cytotoxicitv on 4 kinds of cancer cells through tryphan blue exclusion test and the suppressive effect on viability of 4 kinds of cancer cells via MTT assay. We measured change of mitochondria membrane potential via flow cytometry. The quantitative RT-PCR was used to examine the effect on the revelation of Bcl-2 and Bax which are genes related to apoptosis. We examined the effect on the revelation of Bcl-2 Protein and Bar protein by western blot analysis. Results : In the experiment of tryphan blue exclusion test, the extract of Curcuma aromatica showed more significant killing effect on AS49, HeLa than the control group with density dependent manner, which was statistically significant. In the experiment of MTT assay the extract of Curcuma aromatica showed more suppressive effect on viability of A549, HeLa than the control group with density dependent manner, which was statistically significant. Curcuma aromatica induced apoptosis by decreasing the membrane potential of mitochondria in A549, HeLa. In the experiment of the revelation of genes related to apoptosis, the revelation of Bcl-2 decreased and the revelation of Bax increased in A549, HeLa treated with Curcuma aromatica with dose dependent manner. In the experiment of the revelation of protein related to apoptosis, the protein levels of Bcl-2 decreased and the protein levels of Bax increased in AS49, HeLa treated with Curcuma aromatica with dose dependent manner. Conclusions: From this study, we can infer that Curcuma aromatica has anti-tumor effect on lung cancer cells and uterine carcinoma cells but not on glioma cells and prostate cancer cells.

• Journal of the Korean GEO-environmental Society
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• v.17 no.11
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• pp.45-53
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• 2016

A precast panel wall system resists against the horizontal earth pressure by increasing the shear strength of ground by reinforcement connected to the panel. The application of precast panel wall system is growing to lately minimize the earth work and environmental damage caused by large cut slope and to use the limited land effectively. The ground adhered panel wall system is the construction method that has the panel engraved with natural rock shape to improve the landscape. This system is developed to complete Top-Down method, and it is possible to have vertical cut, and to adhere to in-situ ground, improve construction ability by minimizing the ground relaxation and exclusion the trench and backfill process. In this study the field tests were performed to verify the construction ability about the vertical cut and complete Top-Down process and the construction behavior of ground adhered panel wall system was analyzed by large scale loading test and measurement results during loading test.

• The Journal of Internal Korean Medicine
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• v.29 no.3
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• pp.800-809
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• 2008

Objective : Although chronic prostatitis/chronic pelvic pain syndrcme(CP/CPPS) is a common disease, there is no consensus on the etiology or pathology and treatment. This was a double-blinded, placebo-controlled, randomized clinical trial, investigating the therapeutic effects of the traditional Korean medicine, Bosingunyang-tang(BSGYT). Method : Participants who met US National Institutes of Health (NIH) consensus criteria for CP/CPPS were entered after applying inclusion/exclusion criteria. They were randomized to the BSGYT or placebo group. and treated three times a day for 6 weeks. NIH-Chronic Prostatitis Symptom Index (NIH-CPSI) was used to estimate the clinical symptoms of CP/CPPS. Prostaglandin E2 and ${\beta}$-endorphin in prostatic fluid, collected by 2-glass pre-massage and post-massage test, were analyzed as factors associated with pain and inflammation. Result : The mean decrease in NIH-CPSI total score of the BSGYT group was 11.0 points, which is 5.7 points more than the placebo group. (Mann Whitney test P=0.038) Also the BSGYT group showed three times higher response rate than the placebo group in NIH-CPSI pain subscale score. (Fisher's exact test P=0.027) In those responders, prostaglandin E2 decreased significantly. (Wilcoxon's signed-ranks test P=0.037). No specific side effects were observed. Conclusion : After a 6-week treatment period, BSGYT improved clinical symptoms of CP/CPPS patients by decreasing PGE2 level in prostatic fluid.

• Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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• v.11 no.1
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• pp.5-11
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• 2000

Background and Objectives : Tongue-tie, or partial ankyloglossia, is manifested by an abnormally short and thick lingual frenulum. Degree of tongue-tie varies from the mild to the rare, severe and its treatment of choice is frenulotomy. Theoretically tongue-tie can affect expression of alveolar sounds. The purpose of this study is to evaluate the degree of articulation problem and to evaluate the efficacy of frenulotomy itself on alveolar sounds in tongue-tie patients. Materials and Methods : Prospectively, the authors performed preoperative and postoperative speech evaluation using picture consonants test for tongue-tie patients. Percentage of consonants correct(PCC), mean value of each alveolar phoneme depends on articulation site were evaluated. for exclusion of other articulatory improving factors except of frenulotomy itself, postoperative picture consonants test was performed 1 month after surgery. Results : Preoperative speech evaluation was performed to 37(male 21, female 16) patients and postoperative speech evaluation was performed to 17(male 9, female 8) patients, the other 20 patients were follow-up loss. Low PCC was observed in tongue-tie patients and PCC of female was higher an at of male in 2-4 years old patients. Overall PCC was improved after frenulotomy. Preoperative mean value of liquids and fricatives was lower than the other alveolar phonemes(p＜0.05) and it was improved postoperatively(p＜0.05). Conclusion : Frenulotomy itself can improve the articulation of liquids and fricatives on short follow-up. Speech therapy would be needful for improvement of the other alveolar phonemes.

• Journal of Preventive Medicine and Public Health
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• v.46 no.1
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• pp.10-18
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• 2013

Objectives: We investigated the association between particulate matter less than $10{\mu}m$ in aerodynamic diameter ($PM_{10}$) exposure and non-accidental mortality in Asian populations by meta-analysis, using both time-series and case-crossover analysis. Methods: Among the 819 published studies searched from PubMed and EMBASE using key words related to $PM_{10}$ exposure and non-accidental mortality in Asian countries, 8 time-series and 4 case-crossover studies were selected for meta-analysis after exclusion by selection criteria. We obtained the relative risk (RR) and 95% confidence intervals (CI) of non-accidental mortality per $10{\mu}g/m^3$ increase of daily $PM_{10}$ from each study. We used Q statistics to test the heterogeneity of the results among the different studies and evaluated for publication bias using Begg funnel plot and Egger test. Results: Testing for heterogeneity showed significance (p<0.001); thus, we applied a random-effects model. RR (95% CI) per $10{\mu}g/m^3$ increase of daily $PM_{10}$ for both the time-series and case-crossover studies combined, time-series studies relative risk only, and case-crossover studies only, were 1.0047 (1.0033 to 1.0062), 1.0057 (1.0029 to 1.0086), and 1.0027 (1.0010 to 1.0043), respectively. The non-significant Egger test suggested that this analysis was not likely to have a publication bias. Conclusions: We found a significant positive association between $PM_{10}$ exposure and non-accidental mortality among Asian populations. Continued investigations are encouraged to contribute to the health impact assessment and public health management of air pollution in Asian countries.