• Archives of Pharmacal Research
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• v.27 no.5
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• pp.562-569
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• 2004

Self-assembling nanospheres of hydrophobized pullulan have been developed. Pullulan acetate (PA), as hydrophobized pullulan, was synthesized by acetylation. Carboxymethylated poly(ethylene-glycol) (CMPEG) was introduced into pullulan acetate (PA) through a coupling reaction using N, N'-dicyclohexyl carbodiimide (DCC). A synthesized PA-PEG-PA (abbreviated as PEP) conjugate was confirmed by Fourier transform-infrared (FT-IR) spectroscopy. Since PEP conjugates have amphiphilic characteristics in aqueous solution, polymeric nanoparticles of PEP conjugates were prepared using a simple dialysis method in water. From the analysis of fluorescence excitation spectra primarily, the critical association concentration (CAC) of this conjugate was found to be 0.0063 g/L. Observations by scanning electron microscopy (SEM) showed the spherical morphologies of the PEP nanoparticles. The particle size distribution of the PEP conjugates was determined using photon correlation spectroscopy (PCS) and the intensity-average particle size was 193.3 ${\pm}$ 13.53 nm with a unimodal distribution. Clonazepam (CNZ), as a model drug, was easy to entrap into polymeric nanoparticles of the PEP conjugates. The drug release behavior was mainly diffusion controlled from the core portion.

• Bulletin of the Korean Chemical Society
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• v.34 no.11
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• pp.3350-3356
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• 2013

Quasi-classical trajectory calculations have been carried out for the reaction H+HS by using the newest triplet 3A" potential energy surface (PES). The effects of the collision energy and reagent initial rotational excitation are studied. The cross sections and thermal rate constants for the title reaction are calculated. The results indicate that the integral cross sections (ICSs) are sensitive to the collision energy and almost independent to the initial rotational states. The ro-vibrational distributions for the product $H_2$ at different collision energies are presented. The investigations on the vector correlations are also performed. It is found that the collision energies play a postive role on the forward scatter of the product molecules. There is a negative influence on both the alignment and orientation of the product angular momentum for low collision energy at low energy region. Whereas the influence of collision energy is not obvious at high energy region.

• Proceedings of the Computational Structural Engineering Institute Conference
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• 2007.04a
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• pp.639-644
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• 2007

The accurate peak response estimation of a seismically excited structure with frictional damping system(FDS) is very difficult since the structure with FDS shows nonlinear behavior dependent on the structural period, loading characteristics, and relative magnitude between the frictional force and the excitation load. Previous studies have estimated that by replacing a nonlinear system with an equivalent linear one or by employing the response spectrum obtained based on nonlinear time history and statistical analysis. In the case that on earthquake load is defined with probabilistic characteristics, the corresponding response of the structure with FDS has probabilistic distribution. In this study, nonlinear time history analyses were performed for the structure with FDS subjected to artificial earthquake loads generated using Kanai-Tajimi filter. An equation for the probability density function (PDF) of the displacement response is proposed by adapting the PDF of the normal distribution. Finally, coefficients of the proposed PDF is obtained by regression analysis of the statistical distribution of the time history responses. Finally, the correlation between PDFs and statistical response distribution is presented.

• Bulletin of the Korean Chemical Society
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• v.30 no.7
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• pp.1452-1458
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• 2009

The change in the electronic absorption and emission energy of 7-aminocoumarin derivatives in binary solvent mixtures has been studied. The electronic transition energy along with the Stokes' shift is correlated with the orientation polarizability of the solvent as well as the empirical solvent polarity parameters $E_T$ (30). It is observed that the emission peak shift traces the change of $E_T$ (30) value very closely in binary solvent mixtures. The emission transition more strongly depends on the solvent polarity than the absorption, which indicates the dipole moment gets larger on excitation. From the dependence of the Stokes’ shift of 7-aminocoumarins with the solvent polarity parameters and the ground state dipole moment obtained by the semi-empirical calculations, the excited state dipole moment was estimated. The fluorescence lifetime change of 7-aminocoumarins in binary solvent mixtures was measured and the results are explained in terms of molecular conformation and solvent polarity. The study indicates the empirical solvent polarity $E_T$ (30) is a good measure of microscopic solvent polarity and it probes in general the non-specific solvent interactions.

• Earthquakes and Structures
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• v.8 no.4
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• pp.821-841
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• 2015

This paper proposes a two-stage imaging approach for quantitative inspection of damages in metallic plates using the fundamental anti-symmetric mode of ($A_0$) Lamb wave. The proposed approach employs a number of transducers to transmit and receive $A_0$ Lamb wave pulses, and hence, to sequentially scan the plate structures before and after the presence of damage. The approach is applied to image the corrosion damages, which are simplified as a reduction of plate thickness in this study. In stage-one of the proposed approach a damage location image is reconstructed by analyzing the cross-correlation of the wavelet coefficient calculated from the excitation pulse and scattered wave signals for each transducer pairs to determine the damage location. In stage-two the Lamb wave diffraction tomography is then used to reconstruct a thickness reduction image for evaluating the size and depth of the damage. Finite element simulations are carried out to provide a comprehensive verification of the proposed imaging approach. A number of numerical case studies considering a circular transducer network with eight transducers are used to identify the damages with different locations, sizes and thicknesses. The results show that the proposed methodology is able to accurately identify the damage locations with inaccuracy of the order of few millimeters of a circular inspection area of $100mm^2$ and provide a reasonable estimation of the size and depth of the damages.

• Advances in aircraft and spacecraft science
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• v.2 no.3
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• pp.345-365
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• 2015

This paper focuses on the design, fabrication, testing and analysis of a novel load-bearing element with energy dissipation capability. A single element comprises two von-Mises trusses (VMTs), which are sandwiched between two plates and connected to dashpots that stroke as the VMTs cycle between stable equilibrium states. The elements can be assembled in-plane to form a large plate-like structure or stacked with different properties in each layer for improved load-adaptability. Also introduced in the elements are pre-loaded springs (PLSs) that provide high initial stiffness and allow the element to carry a static load even when the VMTs cannot under harmonic disturbance input. Simulations of the system behavior using the Simscape environment show good overall correlation with test data. Good energy dissipation capability is observed over a frequency range from 0.1 Hz to 2 Hz. The test and simulation results show that a two layer prototype, having one soft VMT layer and one stiff VMT layer, can provide good energy dissipation over a decade of variation in harmonic load amplitude, while retaining the ability to carry static load due to the PLSs. The paper discusses how system design parameter changes affect the static load capability and the hysteresis behavior.

• Journal of Astronomy and Space Sciences
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• v.30 no.4
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• pp.247-253
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• 2013

It has long been known that the magnetospheric particles can precipitate into the atmosphere of the Earth. In this paper we examine such precipitation of energetic electrons using the data obtained from low-altitude polar orbiting satellite observations. We analyze the precipitating electron flux data for many periods selected from a total of 84 storm events identified for 2001-2012. The analysis includes the dependence of precipitation on the Kp index and the electron energy, for which we use three energies E1 > 30 keV, E2 > 100 keV, E3 > 300 keV. We find that the precipitation is best correlated with Kp after a time delay of < 3 hours. Most importantly, the correlation with Kp is notably tighter for lower energy than for higher energy in the sense that the lower energy precipitation flux increases more rapidly with Kp than does the higher energy precipitation flux. Based on this we suggest that the Kp index reflects excitation of a wave that is responsible for scattering of preferably lower energy electrons. The role of waves of other types should become increasingly important for higher energy, for which we suggest to rely on other indicators than Kp if one can identify such an indicator.

• Current Optics and Photonics
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• v.2 no.6
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• pp.589-594
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• 2018

We have investigated the dimensional nature of center-of-mass exciton confinement states in a CdMnTe/CdTe/CdMnTe heterostructure, where the CdTe well is too wide (144 nm) to confine both electrons and holes but able to confine whole excitons in the center-of-mass coordinate. Fine multiple photoluminescence spectra with a few meV separation were observed at 6 K. From the thickness dependence of the transition rate, they were attributed to even numbered center-of-mass exciton confinement states (N = 2, 4, 6, ${\cdots}$, 18). Dimensionality of the center-of-mass exciton confinement states was also investigated in terms of temperature dependence of radiative decay time. At low temperatures (${\leq}12K$), we found that the ground state excitons are likely localized possibly due to the barrier interface fluctuation, resulting in a constant decay time (~350 ps). With increased temperature (${\geq}12K$), localized excitons are thermally released, giving rise to a linear temperature dependence of radiative decay time as an evidence of two-dimensional nature.

• Smart Structures and Systems
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• v.24 no.3
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• pp.361-377
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• 2019

The stiffness of shape memory alloy (SMA) spring while in actuation is represented by an empirical model that is derived from the logistic differential equation. This model correlates the stiffness to the alloy temperature and the functionality of SMA spring as active variable stiffness actuator (VSA) is analyzed based on factors that are the input conditions (activation current, duty cycle and excitation frequency) and operating conditions (pre-stress and mechanical connection). The model parameters are estimated by adopting the nonlinear least square method, henceforth, the model is validated experimentally. The average correlation factor of 0.95 between the model response and experimental results validates the proposed model. In furtherance, the justification is augmented from the comparison with existing stiffness models (logistic curve model and polynomial model). The important distinction from several observations regarding the comparison of the model prediction with the experimental states that it is more superior, flexible and adaptable than the existing. The nature of stiffness variation in the SMA spring is assessed also from the Dynamic Mechanical Thermal Analysis (DMTA), which as well proves the proposal. This model advances the ability to use SMA integrated mechanism for enhanced variable stiffness actuation. The investigation proves that the stiffness of SMA spring may be altered under controlled conditions.

• Computers and Concrete
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• v.27 no.1
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• pp.29-39
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• 2021

This study aimed to develop a method for the determination of the damaged story in reinforced concrete (RC) structure with ambient vibrations, based on modified jerk energy methodology. The damage was taken as a localized reduction in the stiffness of the structural member. For loading, random white noise excitation was used, and dynamic responses from the finite element model (FEM) of 4 story RC shear frame were extracted at nodal points. The data thus obtained from the structure was used in the damage detection and localization algorithm. In the structure, two damage configurations have been introduced. In the first configuration, damage to the structure was artificially caused by a local reduction in the modulus of elasticity. In the second configuration, the damage was caused, using the Elcentro1940 and Kashmir2005 earthquakes in real-time history. The damage was successfully detected if the frequency drop was greater than 5% and the mode shape correlation remained less than 0.8. The results of the damage were also compared to the performance criteria developed in the Seismostruct software. It is demonstrated that the proposed algorithm has effectively detected the existence of the damage and can locate the damaged story for multiple damage scenarios in the RC structure.