• Earthquakes and Structures
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• v.14 no.4
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• pp.337-347
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• 2018

This paper presents some shaking table tests conducted on a 1/4-scaled model with 5-story steel reinforced concrete (SRC) spatial frame with irregular section columns under a series of base excitations with gradually increasing acceleration peaks. The test frame was subjected to a sequence of seismic simulation tests including 10 white noise vibrations and 51 seismic simulations. Each seismic simulation was associated with a different level of seismic disaster. Dynamic characteristic, strain response, acceleration response, displacement response, base shear and hysteretic behavior were analyzed. The test results demonstrate that at the end of the loading process, the failure mechanism of SRC frame with irregular section columns is the beam-hinged failure mechanism, which satisfies the seismic code of "strong column-weak beam". With the increase of acceleration peaks, accumulated damage of the frame increases gradually, which induces that the intrinsic frequency decreases whereas the damping ratio increases, and the peaks of acceleration and displacement occur later. During the loading process, torsion deformation appears and the base shear grows fast firstly and then slowly. The hysteretic curves are symmetric and plump, which shows a good capacity of energy dissipation. In summary, SRC frame with irregular section columns can satisfy the seismic requirements of "no collapse under seldom earthquake", which indicates that this structural system is suitable for the construction in the high seismic intensity zone.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.15 no.9
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• pp.5452-5459
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• 2014

A resonance linear electric generator in a vehicle suspension is a system that performs self-electric generation by collecting the vibration energy when a vehicle runs on a road, and takes the resonance phenomenon to derive large electric generation from slight road surface vibrations. In this paper, the motions of an armature in three different electric generator structures were simulated and the actual generation quantity was calculated and compared with these results. Furthermore, when the vehicle runs on the road, the design improvement for a multi-degree of freedom electric generator was conducted to make the resonance respond to various excitation frequencies, and the change in the resonance points and generation quantity were identified.

• The Korean Journal of Physiology and Pharmacology
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• v.4 no.4
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• pp.275-281
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• 2000

Cholecystokinin (CCK) is a gastrointestinal hormone which plays an important role in satiety and gastric motility. It is also widely distributed throughout the central nervous system, where it appears to be involved in the central control of anxiety, feeding behavior and nociception. Two distinct CCK receptor types, $CCK_A$ and $CCK_B,$ have been found in the brain. Both CCK receptors coexist in the rat nucleus tractus solitarius (NTS), which is the primary center for the coordination of peripheral and central activities related to gastrointestinal, cardiovascular and respiratory functions. In order to study ionic actions of CCK on each type of receptor, we investigated the effects of CCK-8S on neurons located in the NTS of the rat using whole-cell patch-clamp recordings in brainstem slices. Application of CCK-8S, under current clamp, produced a membrane depolarization accompanied by action potential firing. This CCK-evoked excitation was dose-dependent $(10\;nM{\sim}10\;{\mu}M)$ and observed in more than 60% of NTS neurons. Under voltage clamp conditions, CCK-8S induced an inward current with a notably increased spontaneous excitatory synaptic activity. However, CCK-8S did not significantly change the amplitude of pharmacologically isolated and evoked EPSP(C)s. Using selective $CCK_A$ and $CCK_B$ receptor antagonists, we observed two different effects of CCK-8S, which suggest $CCK_A$ receptor-mediated inhibitory and $CCK_B$ receptor-mediated excitatory effects in the NTS. These results may help to explain the ability of CCK to modulate gastrointestinal and other reflex systems in the NTS.

• The Korean Journal of Physiology
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• v.25 no.2
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• pp.133-146
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• 1991

In order to elucidate systematically the effects of serotonin on gastric motility of guinea-pig, the contractile and electrical responses to serotonin were recorded using four kinds of muscle strips prepared from antral circular, antral longitudinal, fundic circular, and fundic longitudinal muscles. Experiments were performed using various methods including isometric contraction recording, transmural electrical field stimulation, junction potential recording, intracellular microelectrode technique, and partition stimulation method. The results were as follows: 1) The effect of serotonin on spontaneous contractions was inhibitory in the circular muscle strips of the antrum and fundus, while it was excitatory in the longitudinal muscle strips of the antrum and fundus. Serotonin changed mainly phasic contractions of both the circular and longitudinal muscle strips in the antrum, while it changed mainly tonic contractions of both the circular and longitudinal muscle strips in the fundus. 2) On the contractions induced by transmural nerve stimulation, serotonin decreased the amplitude in the circular muscle strips of the antrum, but it increased them in the other three groups of muscle strips(antral longitudinal, fundic circular, and fundic longitudinal). 3) On the contractions induced by direct muscle stimulation, serotonin decreased the amplitude in the circular muscle strips of the antrum and fundus. 4) In the fundic circular muscle strips serotonin potentiated excitatory junction potentials (EJPs), and in the antral circular muscle strips it evoked EJPs after inhibitory junction potentials(IJPS). 5) In the antral circular muscle strips serotonin did not affect the slow wave even at the disappearance of spontaneous contractions. On the contrary it increased the amplitude of the slow wave, when the spike component was potentiated and the second component was inhibited. 6) In the antral circular muscle strips the membrane potential was slightly hyperpolarized, but the membrane resistance was not changed. From the above results following conclusions could be made. 1) Serotonin inhibits spontaneous contractions of the circular muscle layer and it increases those of the longitudinal one, irrespective of the gastric region. 2) In the guinea-pig stomach there exists a serotoninergic facilitatory neuromodulation system which exerts its effect on cholinergically mediated contraction. 3) The excitation-contraction decoupling was observed in the effect of serotonin.

• The Korean Journal of Physiology and Pharmacology
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• v.1 no.5
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• pp.467-475
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• 1997

Although one of the major physiological functions of taurine(2-aminoethanesulfonic acid) is the inhibitory action on the central nervous system(CNS), the mechanism of taurine in controlling the neuronal excitation in the CNS has been in controversy. Electrically evoked pEPSP and spontaneous activity induced by the perfusion of low $Mg^{++}-ACSF$ were recorded in the CA1 pyramidal cell layer of the hippocampal slice. To test the inhibitory effect of taurine on spontaneous responses, taurine was treated for 2 min at various concentrations(1 mM-10 mM). Taurine reduced the spontaneous activity by 22.2% at 1 mM, and 100% at 2 mM in low $Mg^{++}-ACSF$. Evoked response was induced by electrical stimulation of Schaffer collateral-commissural fibers. Taurine reduced the evoked response by 11.68% at 3 mM, and 24.25% at 5 mM. Even 20 mM of taurine reduced the evoked response only by 24 % after 5 min treatment. That is, the inhibitory efficacy was much higher in spontaneous activity than in evoked response. The $GABA_A$ receptor antagonist, 100 uM bicuculline, blocked the inhibitory action of taurine, while $GABA_B$ receptor antagonist, 700 uM phaclofen, did not. Taurine blocked the spontaneous activity in the presence of CNQX, and did not block the electrically evoked responce in the presence of APV. The results suggest that taurine causes hyperpolarization in the cell by binding to $GABA_A$ receptor and preferentially attenuates NMDA receptor-mediated hyperexcitation, leaving synaptic transmission unmodified.

• The Korean Journal of Physiology and Pharmacology
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• v.18 no.6
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• pp.517-524
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• 2014

Phasic and tonic ${\gamma}$-aminobutyric acidA ($GABA_A$) receptor-mediated inhibition critically regulate neuronal information processing. As these two inhibitory modalities have distinctive features in their receptor composition, subcellular localization of receptors, and the timing of receptor activation, it has been thought that they might exert distinct roles, if not completely separable, in the regulation of neuronal function. Inhibition should be maintained and regulated depending on changes in network activity, since maintenance of excitation-inhibition balance is essential for proper functioning of the nervous system. In the present study, we investigated how phasic and tonic inhibition are maintained and regulated by different signaling cascades. Inhibitory postsynaptic currents were measured as either electrically evoked events or spontaneous events to investigate regulation of phasic inhibition in layer 2/3 pyramidal neurons of the rat visual cortex. Tonic inhibition was assessed as changes in holding currents by the application of the $GABA_A$ receptor blocker bicuculline. Basal tone of phasic inhibition was maintained by intracellular $Ca^{2+}$ and $Ca^{2+}$/calmodulin-dependent protein kinase II (CaMKII). However, maintenance of tonic inhibition relied on protein kinase A activity. Depolarization of membrane potential (5 min of 0 mV holding) potentiated phasic inhibition via $Ca^{2+}$ and CaMKII but tonic inhibition was not affected. Thus, phasic and tonic inhibition seem to be independently maintained and regulated by different signaling cascades in the same cell. These results suggest that neuromodulatory signals might differentially regulate phasic and tonic inhibition in response to changes in brain states.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.4
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• pp.657-663
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• 2018

In this study, shape optimization was performed to improve the vibration isolation capability of an anti-vibration rubber assembly, which is used in the field option cabin of agricultural tractors. A uniaxial tension test and biaxial tension test were performed to characterize the hyper-elastic material properties of rubber, and the data were used to calibrate the material model used in the finite element analyses. A field test was performed to quantify the input excitation from the tractor and the output response at the cabin frame. To account for the nonlinear behavior of rubber, static analyses were performed and the load-displacement curve of rubber was derived. The stiffness of the rubber was calculated from this curve and input to the harmonic analyses of the cabin. The results were verified using the test data. Taguchi's parameter design method was used to find the optimal shape of the anti-vibration rubber assembly, which indicated a shape with reduced stiffness. The vibration of the cabin frame was reduced by the optimization by as much as 35% compared to the initial design.

• Journal of Soil and Groundwater Environment
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• v.7 no.2
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• pp.35-44
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• 2002

In order to determine the contamination of the aromatic hydrocarbons in soil, a fiber-optic sensing technique with fluorescence detector has been proposed. Previous researches have shown that the optimal condition for detecting benzene, toluene, ethylbenzene, xylene (BTEX) was 260 nm /290 nm (excitation/emission wavelength). However, broader fluorescence spectra of BTEX-polluted soil sample ranging from 300 nm to 600 nm were observed. Additionally, the intensity of fluorescence increased with increasing BTEX concentration, which was conspicuous in the fine-particle soil, The overall results indicated that the suggested technique could be useful for in-situ monitoring system for subsurface oil-storage tank.

• International Journal of Control, Automation, and Systems
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• v.4 no.4
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• pp.414-427
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• 2006

This paper presents an adaptive feedback linearization control scheme for induction motors with simultaneous variation of rotor and stator resistances. Two typical modeling techniques, rotor flux model and stator flux model, have been developed and successfully applied to the controller design and adaptive observer design, respectively. By using stator fluxes as states, over-parametrization in adaptive control can be prevented and control strategy can be developed without the need of nonlinear transformation. It also decrease the relative degree for the flux modulus by one, thereby, yielding, a simple control algorithm. However, when this method is used for flux observer, it cannot guarantee the convergence of flux. Similarly, the rotor flux model may be appropriate for observers, but it is not so for adaptive controllers. In addition, if these two existing methods are merged into overall adaptive control system, it brings about structural complexies. In this paper, we did not use these two modeling methods, and opted for the airgap flux model which takes on only the positive aspects of the existing rotor flux model and stator flux model and prevents structural complexity from occuring. Through theoretical analysis by using Lyapunov's direct method, simulations, and actual experiments, it is shown that stator and rotor resistances converge to their actual values, flux is well estimated, and torque and flux are controlled independently with the measurements of rotor speed, stator currents, and stator voltages. These results were achieved under the persistent excitation condition, which is shown to hold in the simulation.

• Journal of the Earthquake Engineering Society of Korea
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• v.6 no.5
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• pp.19-27
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• 2002

Dynamic responses of a multi-span simply supported bridge are investigated to examine the effect of bearing damage under seismic excitations. The damaged bearings are modeled as sliding elements with friction between the superstructure and the top of the pier. Various values of the friction coefficients are examined to figure out the effect of damaged bearings with various levels of peak ground accelerations. It is found that the global seismic behaviors are significantly influenced by the occurrence of bearing damage. It should be noticed that the most possible location of unseating failure of superstructures differs from that in the bridge model without considering the bearing damage. It can be concluded that the bearing damage may play the major role in the unseating failure of a bridge system, so that the damage of bearings should be included to achieve more rational seismic safety evaluation.