• Development and Reproduction
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• v.17 no.4
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• pp.389-397
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• 2013

FGF9/16/20 signaling pathway specify the developmental fates of notochord, mesenchyme, and neural cells in ascidian embryos. Although a conserved Ras/MEK/Erk/Ets pathway is known to be involved in this signaling, the detailed mechanisms of regulation of FGF signaling pathway have remained largely elusive. In this study, we have isolated Hr-Erf, an ascidian orthologue of vertebrate Erf, to elucidate interactions of transcription factors involved in FGF signaling of the ascidian embryo. The Hr-Erf cDNA encompassed 3110 nucleotides including sequence encoded a predicted polypeptide of 760 amino acids. The polypeptide had the Ets DNA-binding domain in its N-terminal region. In adult animals, Hr-Erf mRNA was predominantly detected in muscle, and at lower levels in ganglion, gills, gonad, hepatopancreas, and stomach by quantitative real-time PCR (QPCR) method. During embryogenesis, Hr-Erf mRNA was detected from eggs to early developmental stage embryos, whereas the transcript levels were decreased after neurula stage. Similar to the QPCR results, maternal transcripts of Hr-Erf was detected in the fertilized eggs by whole-mount in situ hybridization. Maternal mRNA of Hr-Erf was gradually lost from the neurula stage. Zygotic expression of Hr-Erf started in most blastomeres at the 8-cell stage. At gastrula stage, Hr-Erf was specifically expressed in the precursor cells of brain and mesenchyme. When MEK inhibitor was treated, embryos resulted in loss of Hr-Erf expression in mesenchyme cells, and in excess of Hr-Erf in a-line neural cells. These results suggest that zygotic Hr-Erf products are involved in specification of mesenchyme and neural cells.

• Journal of the Korean Dietetic Association
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• v.9 no.3
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• pp.197-208
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• 2003

This study was surveyed to provide the information on current operational practices and issues of contract-managed foodservice companies. Questionnaires were distributed to 79 contract-managed foodservice companies (eight large-size, 48 mid-size, 23 small-size companies) from March to May in 2002. The contract-managed foodservice companies provided averages of 269,184 (range 140,036-503,500), 14,837 (range 450-75,269), and 4,065 (range 930-8,050) meals daily from large, medium, and small-size companies, respectively. The companies managed to averages of 268.2 (160-619) foodservice contracts at large-size companies, 21.9 (5-63) contracts at mid-size companies, and 4.7 (1-10) contracts at small-size companies. The average numbers of dietitians were 298.6 (range 104-671) in large-size companies, 22.2(6-86) in mid-size companies, and 3.8(1-9) in small-size companies. The averages of sales were 156.5 billion at large-size companies, 6.7 billion at mid-size companies, and 1.7 billion at small-size companies in 2001. The contract was two types including management fee contract(5%), and profit and loss contract(95%). The cost ratios for office foodservice were 59.5% at food cost, 24.2% at labor cost, 6.3% at profit, and 10.1% at other cost. For hospital foodservice, the ratios were 54.0% at the food cost, 34.6% at labor cost, 3.0% at profit, and 11.8% at other cost. For high school foodservice, the ratios were 62.2% at the food cost, 21.5% at labor cost, 5.4% at profit, and 11.2% at other cost. When the contractors managed to the foodservice, the most important matters were the sanitation management and customer satisfaction. Also, the difficult problems were excess investment of equipments and low meal prices.

• Journal of the Institute of Electronics and Information Engineers
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• v.53 no.11
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• pp.160-165
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• 2016

The rapidly developing applications of optical fiber in sensors, sensor system and super high speed optical communication have begun to produce tangible demands for optical coupler and connected WDM. we have designed and made Hopper type WDM (national patent NO:10-1502954). The Hopper type WDM is bi-directional $1{\times}3$ WDM of asymmetry Butt coupling for super high speed optical communication. The Hopper type WDM is used central wavelength of each 850nm,1300nm,1550nm. The Hopper type WDM has an excellent merits which the existing WDM and also it has an excellent signal of super high speed and economic in made. The characteristic of Hopper type WDM is superior in ave 0.02-0.03dB as compared with $1{\times}3$ optical coupler to excess loss. Especially, we can expect the utilization of super high speed optical MUX and also can be developed as the high-sensibility signal detected system in using optical sensor system parts.

• Journal of Physiology & Pathology in Korean Medicine
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• v.27 no.2
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• pp.153-166
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• 2013

Yang deficiency pattern is a representative syndrome differentiation. This article is a study on to which categories of modern diseases yang deficiency is assigned by reference to modern clinical papers and the meaning of yang deficiency interpreted with a perspective of Korean Medicine and a modern perspective. Yang deficiency, yang qi deficiency, lack of yang qi and yang qi debilitation are the words found in "Nei Ching" and yang qi can be interpreted as something to warm, drive and arouse. Zhangzhongjing considered recovery or loss of Yang as the key to life in "Shanghanlun". Danxi proposed "Yang being liable to hyperactivity, Yin being insufficient" and emphasized pathological ministerial fire of Yang exuberance rather than physiological ministerial fire of Yang deficiency. Zhangjingyue proposed "Yang not being in excess, Yin being often deficient" and understood growth and decline of yin qi are all led by yang qi and put emphasis on true yin in addition to yang qi. Diseases of yang deficiency pattern are related with decline of metabolic level, hypofunction of internal secretion, disorder of immune function, disorder of automatic nerve system, sympathetic nerve inhibition, metabolic disorder of microelements, increase of cGMP, change of microcirculation, low speed of blood stream, kidney malfunction. Diseases related with kidney are sterility, polycystic ovary syndrome, spinal stenosis, edema, renal failure, IgA nephropathy, erectile dysfunction, nephritis, prostatitis, benign prostatic hyperplasia, decrease of adrenal cortical hormone by nephrotic syndrome, myelodysplastic syndrome. Disease related with heart are heart failure, arrhythmia, cardiomyopathy, atherosclerosis heart disease, hypertension, hyperlipidemia, pulmonary heart disease. Diseases related with spleen are irritable bowel syndrome, ulcerative colitis. Diseases related with liver are hypothyroidism, liver cirrhosis ascites, hepatitis B, chronic hepatitis, hepatic diabetes. Diseases related with lung are allergic rhinitis, cough variant asthma, bronchial asthma, pulmonary emphysema. And diabetes mellitus, metabolic syndrome, aplastic anemia, headache, encephalatrophy, Alzheimer's disease are also related with yang deficiency.

• Korean Journal of Soil Science and Fertilizer
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• v.45 no.4
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• pp.484-491
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• 2012

The hydrological components of a sandy loam soil of nearly level in Chuncheon over 30 years were computed using the E-DiGOR model. Daily simulations were carried out for each year during the period of 1980 to 2009 using standard climate data. Reference evapotranspiration and potential soil evaporation based on Penman-Montheith model were higher during May to August because of the higher atmospheric evaporative demand. Actual soil evaporation was mainly found to be a function of the amount and timing of rainfall, and presumably soil wetness in addition to atmospheric demand. Drainage was affected by rainfall and increased with a higher amount of precipitation and soil water content. Excess drainage occurred throughout rainy months (from July to September), with a peak in July. Therefore, leaching may be a serious problem in the soils all through these months. The 30-year average annual reference evapotranspiration and potential soil evaporation were 951.5 mm and 714.2 mm, respectively. The actual evaporation from bare soil varied between 396.9-528.4 mm and showed comparatively lesser inter-annual variations than drainage. Annual drainage rates below 120 cm soil depth ranged from 477.8 to 1565.9 mm. The long-term mean annual drainage-loss was approximately two times higher than actual soil evaporation.

• Structural Engineering and Mechanics
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• v.49 no.4
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• pp.491-498
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• 2014

During the past years, the protection of the environment has become a major concern out passing the state frontiers to reach a planetary dimension. Depository waste sites have become a serious problem in terms of their locations and costs. On the other hand, the construction industry has a leading place in terms of quantities of waste produced from the start to the end of each construction site, by the large amounts of raw materials used and their respective consequences on the environment. The recycling of quarry wastes products, of demolished concrete, bricks and large quantities of waste resulting from the transformation of marble blocks can provide ideal solutions and advantages for the preservation of the environment, to become a supplementary source of aggregates. The main purpose of this study is to show technically the possibility of recuperating the aggregates of marble wastes as a partial substitute or total in the mortars. The aggregates used in this study is a sand of marble wastes (excess loads of sand exposed to bad weather conditions) of the quarry derived from Fil-fila marble (Skikda, east of Algeria). To achieve this work, we have studied the effect of sand substitution of marble wastes in the mortar with rates of (25, 50, 75, 100%); comparing the results obtained with reference samples (0%), the properties when the samples are fresh, and the mechanical performances of mortars at solid state (loss and gain of weight, dimensional variations). The introduction of recycled sand in the mortars gives good results and can be used as granulates.

• Advances in Energy Research
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• v.7 no.1
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• pp.67-84
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• 2020

Given the recent surge of interest towards utilization of renewable distributed energy resources (DER), in particular in remote areas, this paper aims at designing an optimal hybrid system in order to supply loads of a village located in Esfarayen, North Khorasan, Iran. This paper illustrates the optimal design procedure of a standalone hybrid system which consists of Wind Turbine Generator (WTG), Photo Voltaic (PV), Diesel-generator, and Battery denoting as the Energy Storage System (ESS). The WTGs and PVs are considered as the main producers since the site's ambient conditions are suitable for such producers. Moreover, batteries are employed to smooth out the variable outputs of these renewable resources. To this end, whenever the available power generation is higher than the demanded amount, the excess energy will be stored in ESS to be injected into the system in the time of insufficient power generation. Since the standalone system is assumed to have no connection to the upstream network, it must be able to supply the loads without any load curtailment. In this regard, a Diesel-Generator can also be integrated to achieve zero loss of load. The optimal hybrid system design problem is a discrete optimization problem that is solved, here, by means of a recently-introduced meta-heuristic optimization algorithm known as Lightning Attachment Procedure Optimization (LAPO). The results are compared to those of some other methods and discussed in detail. The results also show that the total cost of the designed stand-alone system in 25 years is around 92M€ which is much less than the grid-connected system with the total cost of 205M€. In summary, the obtained simulation results demonstrate the effectiveness of the utilized optimization algorithm in finding the best results, and the designed hybrid system in serving the remote loads.

• Environmental and Resource Economics Review
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• v.16 no.4
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• pp.947-978
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• 2007

In this paper, we investigated a Value-at-Risk approach to the volatility of two crude oil markets (Brent and Dubai). We also assessed the performance of various VaR models (RiskMetrics, GARCH, IGARCH and FIGARCH models) with the normal and skewed Student-t distribution innovations. The FIGARCH model outperforms the GARCH and IGARCH models in capturing the long memory property in the volatility of crude oil markets returns. This implies that the long memory property is prevalent in the volatility of crude oil returns. In addition, from the results of VaR analysis, the FIGARCH model with the skewed Student-t distribution innovation predicts critical loss more accurately than other models with the normal distribution innovation for both long and short positions. This finding indicates that the skewed Student-t distribution innovation is better for modeling the skewness and excess kurtosis in the distribution of crude oil returns. Overall, these findings might improve the measurement of the dynamics of crude oil prices and provide an accurate estimation of VaR for buyers and sellers in crude oil markets.

• Journal of Microbiology and Biotechnology
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• v.21 no.5
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• pp.519-524
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• 2011

The correlation between alcoholic fermentation rate, measured as carbon dioxide ($CO_2$) evolution, and the rate of hydrogen sulfide ($H_2S$) formation during wine production was investigated. Both rates and the resulting concentration peaks in fermentor headspace $H_2S$ were directly impacted by yeast assimilable nitrogenous compounds in the grape juice. A series of model fermentations was conducted in temperature-controlled and stirred fermentors using a complex model juice with defined concentrations of ammonium ions and/or amino acids. The fermentation rate was measured indirectly by noting the weight loss of the fermentor; $H_2S$ was quantitatively trapped in realtime using a pre-calibrated $H_2S$ detection tube which was inserted into a fermentor gas relief port. Evolution rates for $CO_2$ and $H_2S$ as well as the relative ratios between them were calculated. These fermentations confirmed that total sulfide formation was strongly yeast strain-dependent, and high concentrations of yeast assimilable nitrogen did not necessarily protect against elevated $H_2S$ formation. High initial concentrations of ammonium ions via addition of diammonium phosphate (DAP) caused a higher evolution of $H_2S$ when compared with a non-supplemented but nondeficient juice. It was observed that the excess availability of a certain yeast assimilable amino acid, arginine, could result in a more sustained $CO_2$ production rate throughout the wine fermentation. The contribution of yeast assimilable amino acids from conventional commercial yeast foods to lowering of the $H_2S$ formation was marginal.

• The Journal of the Acoustical Society of Korea
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• v.34 no.6
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• pp.455-462
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• 2015

It is well known that warm eddy is frequently developed through the year in the East Sea. The warm eddy may affect sound propagation due to changes of sound velocity structures in the sea water. To verify the effects of the warm eddy for long-range sound propagation, transmission loss and performance surface, which were used mean direct signal excess range generated by sound propagation modeling using re-analyzed climatology data on March 23th in 2007 were analysed. From these analyses, we found that characteristics of sound propagation in the sea water are changed by the warm eddy, and boundaries of the warm eddy act as a barrier for long-range sound propagation. Furthermore, these disadvantages of the eddy related to sound propagation were increased when the sea bottom depth is shallow.