• Structural Engineering and Mechanics
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• v.72 no.3
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• pp.355-366
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• 2019

Self-centering wall (SCW) is a resilient and sustainable structural system which incorporates unbonded posttensioning (PT) tendons to provide self-centering (SC) capacity along with supplementary dissipators to dissipate seismic energy. Hysteretic energy dissipators are usually placed at two sides of SCWs to facilitate ease of postearthquake examination and convenient replacement. To achieve a good prediction for the skeleton curve of the wall, this paper firstly developed an analytical investigation on lateral load responses of self-centering walls with distributed vertical dampers (VD-SCWs) using the concept of elastic theory. A simplified method for the calculation of limit state points is developed and validated by experimental results and can be used in the design of the system. Based on the analytical results, parametric analysis is conducted to investigate the influence of damper and tendon parameters on the performance of VD-SCWs. The results show that the proposed approach has a better prediction accuracy with less computational effects than the Perez method. As compared with previous experimental results, the proposed method achieves up to 60.1% additional accuracy at the effective linear limit (DLL) of SCWs. The base shear at point DLL is increased by 62.5% when the damper force is increased from 0kN to 80kN. The wall stiffness after point ELL is reduced by 69.5% when the tendon stiffness is reduced by 75.0%. The roof deformation at point LLP is reduced by 74.1% when the initial tendon stress is increased from $0.45f_{pu}$ to $0.65f_{pu}$.

• The Journal of the Convergence on Culture Technology
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• v.5 no.1
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• pp.153-167
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• 2019

Purpose: The aim of this study was to examine factors influencing health-related quality of life in middle and old adult one-person households. Method: This study carried out secondary analysis using the data from the $7^{th}$ Korean National Health and Nutrition Examination Survey. Subject samples who were selected are 497 middle and old adult one-person households over 40 years. Data were analyzed using descriptive statistics, simple and multiple regression techniques with the SPSS/WIN 24 program. Result: Factors influencing health-related quality of life in middle adult one-person households were activity limitation, depression, exercise, smoking habits with 57% prediction. In male old adult one-person households they were subjective health, metabolic syndrome, activity limitation, perceived stress with 44.8% prediction and in female old adult one-person households they were subjective health, activity limitation, home income with 35.9% prediction. Conclusion: Therefore, to improve their health-related quality of life it needs to develop & to apply national and local promotion policy and intervention program on health-related quality of life of middle and old adult one-person households.

• Journal of Ginseng Research
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• v.45 no.1
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• pp.108-118
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• 2021

Background: Korean ginseng (Panax ginseng Meyer) contains a variety of ginsenosides that can be metabolized to a biologically active substance, compound K. Previous research showed that compound K could be enriched in the red ginseng extract (RGE) after hydrolysis by pectinase. The current study investigated whether the enzymatically hydrolyzed red ginseng extract (HRGE) containing a notable level of compound K has cognitive improving and neuroprotective effects. Methods: A scopolamine-induced hypomnesic mouse model was subjected to behavioral tasks, such as the Y-maze, passive avoidance, and the Morris water maze tests. After sacrificing the mice, the brains were collected, histologically examined (hematoxylin and eosin staining), and the expressions of antioxidant proteins analyzed by western blot. Results: Behavioral assessment indicated that the oral administration of HRGE at a dosage of 300 mg/kg body weight reversed scopolamine-induced learning and memory deficits. Histological examination demonstrated that the hippocampal damage observed in scopolamine-treated mouse brains was reduced by HRGE administration. In addition, HRGE administration increased the expression of nuclear-factor-E2-related factor 2 and its downstream antioxidant enzymes NAD(P)H:quinone oxidoreductase and heme oxygenase-1 in hippocampal tissue homogenates. An in vitro assay using HT22 mouse hippocampal neuronal cells demonstrated that HRGE treatment attenuated glutamate-induced cytotoxicity by decreasing the intracellular levels of reactive oxygen species. Conclusion: These findings suggest that HRGE administration can effectively alleviate hippocampus-mediated cognitive impairment, possibly through cytoprotective mechanisms, preventing oxidative-stress-induced neuronal cell death via the upregulation of phase 2 antioxidant molecules.

• Journal of Convergence for Information Technology
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• v.11 no.3
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• pp.46-53
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• 2021

This study aimed to compare general and female health-related factor between day-work and shift-work worker. It is based on the data of the Korea National Health&Nutrition Examination Survey(KNHANES) 2nd year on 7th period. The number of participants was 10,430. Out of the participants, 1,995 workers' dara was analyzed. The age, marital status, education level, occupational status and childbirth experience of female workers indicated significant differences between day and shift work. By contrast, health-related quality of life did not represent significant differences these factors; income, subjective health cognition, stress perception, depression experience, menarcheal age, menopausal age and breastfeeding period. The shift work is inevitably implemented as an industrial development and flexible work hours. Therefore, social and national attention and measures as well as those of individual workers are required to reduce the side effects from shiftwork.

• Journal of Oral Medicine and Pain
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• v.46 no.4
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• pp.161-164
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• 2021

The foramen of Huschke (FH) or foramen tympanicum is a persistent bony defect connecting the external auditory canal (EAC) to the temporomandibular joint (TMJ). It arises from an incomplete ossification of the tympanic part of the temporal bone that persists after the age of 5. If a herniation exists in the TMJ, otological symptoms may occur. An 80-year-old female patient complained of noise in her left TMJ and otorrhea in her left ear. On her cone beam computed tomography images, there were only degenerative joint disease signs on her left mandibular condyle. However, her computed tomography images revealed that the soft tissue of the TMJ herniate into the EAC. Additional examination was planned for the further evaluation. But the patient no longer visited the hospital due to her systemic health status, and symptoms disappeared spontaneously without any treatments. Usually this type of herniation is very rare, but years of mechanical stress from mastication may result in weakening and widening of the foramen with age. Therefore, although FH is usually congenital, sometimes it may be acquired in the elderly. The treatment plan should be determined in consideration of the patient's symptom level and the patient's general health status. If the clinical symptoms are not severe, no treatment is required.

• Journal of Ginseng Research
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• v.46 no.4
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• pp.543-549
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• 2022

Background: In physical activity or labor, the human body is in a state of high intensity stress, and all parts or physiological functions of the body respond positively to maintain or balance the need for movement. The human body has many physiological changes in the process of movement, and fatigue is the external manifestation of various complex changes inside the human body. Fatigue is also a physiological mechanism of self-protection after the body reaches a certain level of activity, which can prevent the occurrence of life-threatening excessive functional failure. The generation of fatigue is a very complex process, and its mechanism has not been concluded yet. Therefore, it is an important work to search and screen the effective components of natural plants that have anti-fatigue effect and to explore their mechanism. Methods: This was a 8-week, randomized, double-blind, placebo-controlled clinical trial. A total of 110 subjects who passed physical examination were included according to the scheme design, and randomly divided into a test group which was given KRG and a placebo control group. The calculation is carried out according to the standard of sub-high-intensity exercise test. Results: There was no adverse effect on safety index of subjects after taking red ginseng capsule. After KRG treatment, subjective strength grade is significant lower than placebo treatment. Blood lactic acid content is significantly get lower after trial in KRG group, and significant lower than placebo group. Creatine phosphokinase(CK) content is significantly get lower after trial in KRG group, and significant lower than placebo group. Conclusion: According to the criterion in the test scheme, the result shows that KRG is helpful on relieving physical fatigue.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.33 no.3
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• pp.73-81
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• 2022

Since dissociative identity disorder (DID) has symptoms similar to schizophrenia, such as auditory hallucinations and delusional thoughts of being controlled, there are difficulties in its differential diagnosis. A 16-year-old adolescent male patient who was previously diagnosed with schizophrenia from a different hospital was admitted to our inpatient psychiatric unit for the evaluation of auditory hallucinations and suicide attempts. Through psychiatric evaluations, it was determined that the patient suffered from identity alternation, dissociation, and amnesia. As for the diagnostic evaluations, the following measures were implemented: a psychiatric interview regarding the diagnostic criteria, mental status examination, laboratory tests, brain imaging studies, electroencephalography, and full psychological test for adolescents, and the self-reported measure of the Adolescent Dissociative Experiences Scale. The patient was diagnosed with DID, and the following treatments were administered: pharmacotherapy, ego state therapy, psychoeducation regarding emotions, trauma-focused psychotherapy including stabilization, and family therapy. Following treatment, in the internal dimensions, the patient was able to recognize the nine alternate identities in charge of his emotions, which established a basis for the potential integration of identities. In the external dimensions, he showed improvements in the aspects of family conflicts and issue of school refusal. This is the first reported case of DID in an adolescent in Korea; it emphasizes the consideration of DID in the differential diagnosis of other mental illnesses such as schizophrenia, bipolar disorder, and posttraumatic stress disorder and expands the treatment opportunities for DID by sharing the procedures of ego state therapy.

• Journal of The Korean Society of Integrative Medicine
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• v.9 no.3
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• pp.47-58
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• 2021

Purpose : This study aimed to investigate the association between asthma and oral health and factors influencing asthma in adults. We also investigated whether asthma is related to mental health and physiological factors of blood. Methods : Data from 12,639 adults was taken from the 7th period (2016~2018) Korea National Health and Nutrition Examination Survey and analyzed using with SPSS 22.0 statistical program. Statistical analysis of data included frequency analysis, cross-analysis, and logistic regression analysis. For continuous data, an independent sample t-test was performed. The statistical significance level was defined as 0.05. Results : The probability of asthma occurrence was statistically different within general characteristics (gender, age, school grade, income, and drinking). By independent variables in a logistic regression analysis, the asthma diagnosis group had more people with speech discomfort (OR=1.37), chewing discomfort (OR=1.29), and oral pain (OR=.73). We found that people with asthma had a more unfavorable perception of their health (OR=1.73), suffered more depression (OR=.45), stress (OR=.66), and limited activity (OR=2.38). Moreover, the white blood cell count (OR=1.10) and high sensitivity C-reactive protein test (OR=1.06) also showed higher values than the control group. Conclusion : Our study showed that oral health and mental health were associated with the asthma, and influencing factors were oral health and behavior and mental health-related characteristics. Therefore, it is necessary to understand asthma-related risk factors for oral health and recognize the importance of systematic oral care education and regular dental visits for patients receiving asthma treatment. Thus, this study provides valuable insights on appropriate oral health management and prevention of asthma in patients.

• The Journal of the Convergence on Culture Technology
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• v.7 no.2
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• pp.207-216
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• 2021

This study was conducted on 315 women in their 20s and 40s living in Changwon, South Gyeongsang Province, and recorded in a self-recorded format using the questionnaire survey method. In this study, the skin type according to the skin condition was not applied for 30 minutes after washing and checking the cheek area through the examination method to distinguish it by intelligence, neutral, dryness and boredom to see the interaction with each condition. The X2-test was conducted to find out the relevance between each factor and the data processing was done using PC/SAS. We reached at following conclusions. We can find some connections between skin condition and age, job, marriage by statistics(p<0.01). Each value of X2-TEST was 42.961(p<0.001) and 7.345(p<0.05). The pimples are shown after stress on cheek, chin and around neck easily. We also find some connections between skin trouble reaction and the beginning of pimple shown time(p<0.01).

• The Korea Journal of Herbology
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• v.30 no.2
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• pp.1-9
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• 2015

Objectives : The present study was conducted to examine whether Toosendan Fructus has an ameliorative effect on diabetes-induced alterations such as oxidative stress and inflammation in the pancreas of non-obese diabetic (NOD) mice, a model of human type I diabetes. Methods : Extracts of Toosendan Fructus (ETF) were administered to NOD mice at three doses (50 mg/kg, 100 mg/kg and 200 mg/kg). Mice at 18 weeks of age were measured glucose tolerance using intraperitoneal glucose tolerance test. After 28 weeks of ETF treatment, glucose, total cholesterol (TC), triglyceride (TG), and proinflammatory cytokines in serum, western blot analyses and a histopathological examination in pancreas tissue, and on the onset of diabetes were investigated. Results : The results showed that levels of glucose, glucose tolerance, TC, TG, interferon-${\gamma}$, interleukin (IL)-1 ${\beta}$, IL-6, and IL-12 in serum were down-regulated, while IL-4, IL-10, SOD, and catalase significantly increased. In addition, ETF improved protein expression of proinflammatory mediaters (such as cyclooxygenase-2, and inducible nitric oxide synthase) and a proapoptotic protein (caspase-3) in the pancreatic tissue. Also, in the groups treated with ETF (100 mg/kg or 200 mg/kg), insulitis and infiltration of granulocytes were alleviated. Conclusions : Based on these results, the anti-diabetic effect of ETF may be due to its anti-inflammatory and antioxidant effect. Our findings support the therapeutic evidence for Toosendan Fructus ameliorating the development of diabetic pancreatic damage via regulating inflammation and apoptosis. Our future studies will be focused on the search for active compounds in these extracts.