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Management of Infections with Rapidly Growing Mycobacteria after Unexpected Complications of Skin and Subcutaneous Surgical Procedures

  • Lim, Jong-Min;Kim, Jong-Hwan;Yang, Ho-Jik
    • Archives of Plastic Surgery
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    • v.39 no.1
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    • pp.18-24
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    • 2012
  • Background : Infection caused by rapidly growing mycobacteria (RGM) is not uncommon, and the prevalence of RGM infection has been increasing. Clinical diagnosis is difficult because there are no characteristic clinical features. There is also no standard antibiotic regimen for treating RGM infection. A small series of patients with RGM infections was studied to examine their treatments and outcomes. Methods : A total of 5 patients who had developed postoperative infections from January 2009 to December 2010 were retrospectively reviewed. Patients were initially screened using a mycobacteria rapid screening test (polymerase chain reaction [PCR]-reverse blot hybridization assay). To confirm mycobacterial infection, specimens were cultured for nontuberculous mycobacteria and analyzed by 16 S ribosomal RNA and rpoB gene PCR. Results : The patients were treated with intravenous antibiotics during hospitalization, and oral antibiotics were administered after discharge. The mean duration of follow-up was 9 months, and all patients were completely cured of infection with a regimen of a combination of antibiotics plus surgical treatment. Although none of the patients developed recurrence, there were complications at the site of infection, including hypertrophic scarring, pigmentation, and disfigurement. Conclusions : Combination antibiotic therapy plus drainage of surgical abscesses appeared to be effective for the RGM infections seen in our patients. Although neither the exact dosage nor a standardized regimen has been firmly established, we propose that our treatment can provide an option for the management of rapidly growing mycobacterial infection.

Prediction of the Blade Flapping Angle for Korean Utility Helicopter by Applying Indirect Method (간접기법을 이용한 한국형 기동헬기 블레이드 플래핑 각도 예측)

  • Kim, Young-Jin;Lee, Sang-Gi;Lee, Seung-Jae;Chang, In-ki;Shim, Dai-Sung
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.43 no.10
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    • pp.888-895
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    • 2015
  • This paper shows an approximate equation which calculates a flapping angle of blade for verification of KUH safety area. The flapping behavior of blade must be reviewed in an aspect of safety because of a collision possibility with airframe. However, it is difficult to measure an exact flapping angle during flight. A prediction equation of a coning angle is derived from aeromechanics and that of a dynamic flapping angle is derived from analysis results in development phase, respectively. Following, the equations are verified by comparison the flapping angle through an aircraft simulation test to a calculation. Finally, the safety area, which was established in development phase, is verified by calculating a flapping angle during the flight which is required by the terms of safety based on AC29 and FAR29.

A Study on the Comparative Utilization of Cone Penetration Test and Seismic Prospecting (콘관입시험과 탄성파탐사의 비교 이용에 관한 연구)

  • 송무영;김팔규;김연천;류권일
    • The Journal of Engineering Geology
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    • v.8 no.1
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    • pp.25-34
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    • 1998
  • It is not easy to understand exact soil properties, because soil is nonhomogeneous and anisotropic. There are raany inefficient cases in aspect of time and economy in site survey. So this study tried to analyze the correlation of cone resistance and seismic velocity in order to present an efficient method in ground investigation. A cone penetrometer is frequently used to investigate soil properties, which are especially fit to investigate coastal soft ground. A portable cone penetrometer was used in this research. A portable cone penetrometer has an advantage in investigating the state of soil swiftly and is convenient to manipulate. Also, seismic prospecting is one of the most PoPular methods among geophysical prospecting methods in the estimation of ground properties and its usage is continuously increasing in the survey of soft ground Cone resistance makes a regular group according to stratum in each depth. The results of seismic prospecting show a tendency to have a certain coherence according to the boundary of straturft Therefore, cone resistance and seisrnic prospecting have considerable relations that rnay irnprnve the efficiency of ground investigation.

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A Comparative Study on the Anthropometric Method - Anthropometric Point and Line - (인체측정(人體測定) 방법(方法)에 관(關)한 비교(比較) 연구(硏究) - 인체측정(人體測定) 기준점(基準點), 기준선(基準線)을 중심(中心)으로 -)

  • Kwon, Young-Ja;Shim, Boo-Ja
    • Journal of Fashion Business
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    • v.5 no.4
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    • pp.89-100
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    • 2001
  • The major purpose of this study is to show exact and convenient devices and minimize error in body measurement. This study was referred to 13 records and compared 6 items that the investigator's opinion has been differed about anthropometric point and line and suggested convenient and radical device, and measured by if need be. The 30 students from 20 to 25 ages were measured and data was analyzed by mean, std. deviation and paired t-test. The results are as follows. 1. Side neck point has been suggested many devices, but was suggested in this study to decide by M. trapezius, cervicale point and fossa jugularis point. 2. Shoulder point was suggested to decide by point of 1/2 armhole depth, upper arm depth and shoulder depth except acromion point. 3. Waist circumference line has been differed between horizontal line and natural line. The result of measurements was no significant difference between two methods and natural line was convenience. Waist circumference line must considered two methods together for garment construction and somato type. 4. The standard of hip circumference line has been differed between buttock point and trochanterion point. The result of measurements was significant difference between two methods, but two point must considered together because of body type. 5. Chest circumference line at scye has been differed between horizontal line and natural line. The result of measurements was significant difference between two methods and natural line was convenience. Chest circumference line at scye must studied to decide method the line for garment construction.

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The Effect of Personalization and Accessibility of Online Shopping Cart on Fashion Product Purchase Intention -Focusing on the Mediation Roles of Psychological Ownership- (온라인 장바구니의 개인화와 접근성이 패션제품 구매의도에 미치는 영향 -심리적 소유감의 매개효과를 중심으로-)

  • Dong, Jiyoon;Hur, Hee Jin;Choo, Ho Jung
    • Journal of the Korean Society of Clothing and Textiles
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    • v.43 no.6
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    • pp.910-929
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    • 2019
  • This study identifies the effects of the characteristics of an online shopping cart based on the theory of psychological ownership. This study created experimental stimuli similar to the actual fashion website in order to derive the exact emotional and behavioral responses of participants. To test the hypotheses, four experimental groups of 2 (personalization: high / low) × 2 (accessibility: high / low) were formed with between-subject design. We selected 201 women in 20-30s as participants and they responded to an online survey after experiencing website stimuli. The collected data were analyzed using SPSS 25.0 and SPSS PROCESS Macro program. The results show that the effects of personalization of an online shopping cart on the purchase intention of the fashion product in the cart is significant; in addition, the main effect of personalization of cart on consumer's psychological ownership was confirmed. It was also found that the path of personalization of the online shopping cart to purchase intention through psychological ownership was significant. The findings of this study contributes to the extension of online shopping cart research and provide suggestions to recognize the important role of psychological ownership in increasing the purchase conversion rate.

Influence of elderly-related experience on attitude toward elderly in dental hygiene students (일 개 대학 치위생과 학생들의 노인관련 경험이 노인에 대한 태도에 미치는 영향)

  • Jun, Bo-Hye;Choi, Young-Suk
    • Journal of Korean society of Dental Hygiene
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    • v.15 no.6
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    • pp.1019-1026
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    • 2015
  • Objectives: The purpose of the study is to investigate the influence of elderly-related experience on attitude toward elderly in dental hygiene students. Methods: A self-reported questionnaire was completed by 213 dental hygiene students in Suwon from November 21 to 30, 2012. The questionnaire consisted of general characteristics of the subjects, elderly-related experience, knowledge on elderly, and attitude toward elderly by Likert 7 points scale. The instrument for knowledge on elderly was adapted from facts on aging quiz-I by Palmore and modified by Kim et al. Data were analyzed by t test, one way ANOVA, and multiple regression analysis using SPSS 21.0 program. Results: The attitude toward the elderly was $2.79{\pm}0.42$. The elderly-related experience had a positive influence on the attitude toward elderly(p=0.019) according to the level of experiencing the elderly(r=0.161, p<0.05). The influence of elderly-related experience on attitude toward the elderly showed that an experiencing variable is key factor in predicted variable of the attitude toward the elderly(${\beta}$=0.177 p=0.015). Conclusions: Elderly-related experience had an effect on positive attitude toward the elderly people in the dental hygiene students. It is necessary to develop and implement the education program for the exact knowledge and attitude toward the elderly.

Analysis System for Practical Dynamic Load with Hybrid Method under Random Frequency Vibration (불규칙 가진시 하이브리드기법을 이용한 실동하중 해석시스템)

  • Song, Joon-Hyuk;Yang, Sung-Mo;Kang, Hee-Yong;Yu, Hyo-Sun
    • Transactions of the Korean Society of Automotive Engineers
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    • v.16 no.6
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    • pp.33-38
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    • 2008
  • Most structures of vehicle are composed of many substructures connected to one another by various types of mechanical joints. In vehicle engineering, it is important to study these jointed structures under random frequency vibration for the evaluations of fatigue life and stress concentration exactly. It is rarely obtained the accurate load history of specified positions in a jointed structure because of the errors such as modeling, measurement, and etc. In the beginning of design, exact load data are actually necessary for the fatigue strength and life analysis to minimize the cost and time of designing. In this paper, the hybrid method of practical dynamic load determination is developed by the combination of the principal stresses from F. E. Analysis and test of a jointed structure. Least square pseudo inverse matrix is adopted to obtain an inverse matrix of analyzed stresses matrix. The error minimization method utilizes the inaccurate measured error and the shifting error that the whole data is stiffed over real data. The least square criterion is adopted to avoid these errors. Finally, to verify the proposed system, a heavy-duty bus is analyzed. This measurement and prediction technology can be extended to the different jointed structures.

Microsatellite Instability Is Associated with the Clinicopathologic Features of Gastric Cancer in Sporadic Gastric Cancer Patients

  • Kim, Shin-Hyuk;Ahn, Byung-Kyu;Nam, Young-Su;Pyo, Joo-Youn;Oh, Young-Ha;Lee, Kang-Hong
    • Journal of Gastric Cancer
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    • v.10 no.4
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    • pp.149-154
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    • 2010
  • Purpose: Replication error is an important mechanism in carcinogenesis. The microsatellite instability (MSI-H) of colorectal cancers is associated with the development of multiple cancers. The influence of MSI-H on the development of multiple gastric cancers in sporadic gastric cancer patients has not been defined. This study was performed to reveal the association between the clinicopathologic features and MSI in sporadic gastric cancers. Materials and Methods: Between July 2004 and March 2009, the clinicopathologic characteristics, including MSI status, were evaluated in 128 consecutive patients with sporadic gastric cancers. None of the patients had hereditary non-polyposis colorectal cancer of familial gastric cancer. The markers that were recommended by the NCI to determine the MSI status for colorectal cancers were used Results: MSI-H cancers were found in 10.9% of the patients (14/128). Synchronous gastric cancers were shown in 4 patients (3.1%). Synchronous cancers were found in 2 of 14 patients with MSI-H gastric cancer (14.3%) and 2 of 114 patients with MSS gastric cancer (1.8%; P=0.059, Fisher's exact test). Among the patients with synchronous cancer 50% (2/4) had MSI-H cancer, but 9.7% of the patients (12/124) without synchronous cancer had MSI-H cancer. MSI-H (RR, 24.7; 95% CI, 1.5~398.9; P=0.024) was related with to synchronous gastric cancer, but age, gender, family history, histologic type, location, gross morphology, size, and stage were not related to synchronous gastric cancer. Conclusions: MSI is associated with the intestinal-type gastric cancer and the presence of multiple gastric cancers in patients with sporadic gastric cancer. Special attention to the presence of synchronous and the development of metachronous multiple cancer in patients with MSI-H gastric cancer is needed.

Association of HLA Genotype and Fulminant Type 1 Diabetes in Koreans

  • Kwak, Soo Heon;Kim, Yoon Ji;Chae, Jeesoo;Lee, Cue Hyunkyu;Han, Buhm;Kim, Jong-Il;Jung, Hye Seung;Cho, Young Min;Park, Kyong Soo
    • Genomics & Informatics
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    • v.13 no.4
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    • pp.126-131
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    • 2015
  • Fulminant type 1 diabetes (T1DM) is a distinct subtype of T1DM that is characterized by rapid onset hyperglycemia, ketoacidosis, absolute insulin deficiency, and near normal levels of glycated hemoglobin at initial presentation. Although it has been reported that class II human leukocyte antigen (HLA) genotype is associated with fulminant T1DM, the genetic predisposition is not fully understood. In this study we investigated the HLA genotype and haplotype in 11 Korean cases of fulminant T1DM using imputation of whole exome sequencing data and compared its frequencies with 413 participants of the Korean Reference Panel. The $HLA-DRB1^*04:05-HLA-DQB1^*04:01$ haplotype was significantly associated with increased risk of fulminant T1DM in Fisher's exact test (odds ratio [OR], 4.11; 95% confidence interval [CI], 1.56 to 10.86; p = 0.009). A histidine residue at $HLA-DR{\beta}1$ position 13 was marginally associated with increased risk of fulminant T1DM (OR, 2.45; 95% CI, 1.01 to 5.94; p = 0.054). Although we had limited statistical power, we provide evidence that HLA haplotype and amino acid change can be a genetic risk factor of fulminant T1DM in Koreans. Further large-scale research is required to confirm these findings.

Relationship between anterior disc displacement with/without reduction and effusion in temporomandibular disorder patients using magnetic resonance imaging

  • Koh, Kwang-Joon;Park, Ha-Na;Kim, Kyoung-A
    • Imaging Science in Dentistry
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    • v.43 no.4
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    • pp.245-251
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    • 2013
  • Purpose: This study was performed to evaluate the relationship between anterior disc displacement and effusion in temporomandibular disorder (TMD) patients using magnetic resonance imaging (MRI). Materials and Methods: The study subjects included 253 TMD patients. MRI examinations were performed using a 1.5 T MRI scanner. T1- and T2-weighted images with para-sagittal and para-coronal images were obtained. According to the MRI findings, temporomandibular joint (TMJ) disc positions were divided into 3 subgroups: normal, anterior disc displacement with reduction (DWR), and anterior disc displacement without reduction (DWOR). The cases of effusion were divided into 4 groups: normal, mild (E1), moderate (E2), and marked effusion (E3). Statistical analysis was made by the Fisher's exact test using SPSS (version 12.0, SPSS Inc., Chicago, IL, USA). Results: The subjects consisted of 62 males and 191 females with a mean age of 28.5 years. Of the 253 patients, T1- and T2-weighted images revealed 34 (13.4%) normal, DWR in 103 (40.7%), and DWOR in 116 (45.9%) on the right side and 37 (14.6%) normal, DWR in 94 (37.2%), and DWOR in 122 (48.2%) joints on the left side. Also, T2-images revealed 82 (32.4%) normal, 78 (30.8%) E1, 51 (20.2%) E2, and 42 (16.6%) E3 joints on the right side and 79 (31.2%) normal, 85 (33.6%) E1, 57 (22.5%) E2, and 32 (12.7%) E3 on the left side. There was no difference between the right and left side. Conclusion: Anterior disc displacement was not related to the MRI findings of effusion in TMD patients (P>0.05).