• Title/Summary/Keyword: Exact test

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Study on Anti-estrogenic Activity of DEHP as an Endocrine Disruption Chemical (내분비 교란성 DEHP의 항-에스트로젠 활성에 관한 연구)

  • Kim, Eun-Joo
    • Journal of Environmental Health Sciences
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    • v.29 no.2
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    • pp.7-15
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    • 2003
  • Di-2-ethylhexyl phthalate (DEHP), is a widely used plasticizer known to be a suspected endocrine disrupter, but its exact effects on aquatic organisms are not yet known. When Japanese medaka (Oryzias latipes) were exposed from the time of hatching to 3 months of age to an aqueous DEHP solution at nominal concentrations of 1, 10, and 50 $\mu\textrm{g}$/l, DEHP treated female fish showed distinct reproductive effect. And the midge (Chironomus riparius.). an aquatic invertebrate, was exposed to DEHP to evaluate the effects on reproductive processes via sediment toxicity. The test endpoints included emergence, sex ratio, fecundity, and the viability of F1 offspring egg ropes. The result implied that the normal developmental and/or reproductive processes in C. riparius had been disrupted when exposed to DEHP, the effect also being displayed in the next generation. In summary, DEHP hinders the development of reproductive organs in the female Japanese medaka and C. riparius.

A Study on Consumers' Advertising Discriminatory Competencies and the Related Factors (소비자의 광고판별능력과 관련요인에 관한 연구 -기만광고판별을 중심으로-)

  • 이기춘
    • Journal of the Korean Home Economics Association
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    • v.28 no.2
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    • pp.91-106
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    • 1990
  • This study focuses on consumers' advertising discriminatory competencies and the influencing facors. So the objects of this study are as follows : 1) to identify the overall level of advertising discriminatory competencies. 2) to examine if consumer attitude variables have significant effects on the ads. discriminatory competenceis. 3) to examine if the frequencies of contacting advertising variable have significant effects on the ads. discriminatory competencies. 4) to examine if socio-economics variables-age, educational level, monthly family income, occupational status-have significant effects on the ads. discriminatory competencies. 5) to find out the independent influence of variables related to the ads. discriminatory competencies. For this purpose, a survey was conducted using questionaires and advertisement papers. The data used in this study included 194 Homemakers living in Seoul. The ads. used in this study included ads. of diary products like foods, drinks, medicine, cosmetic, detergent in TV, radio, newspaper and magagine. Statistics were Frequency Distribution, Mean, percentile, ANOVA, Scheff -test, Pearsons' Correlation, Multiple Regrassion Analysis. Major findings were as follows : First, in 26 items(70%) of 37 items measured consumers' ads. discriminatory competencies, the rate of right answer was below 50%, so over the half of consumers were misleaded by the deceptive ads. Second, consumers' ads. discriminatory competencies differed significantly according to consumer attitude variables but no according to the frequency of contacting advertising. Third, according to socio-demographic variables-age, educational level, monthly family income, occupational status-advertising discriminatory competencies differed significantly. In group of lower age, higher educational level, higher income and professional occupation status, the level of ads. discriminatory competencies were high. Forth, the most influencing variabel on ads. disciriminatory competencies were eudcational level and in turn general attitude toward ads., attitude toward consumerism. This three variables explain 22.9% of dependent variable's variance. From these findings, the following suggestions are made, First, the consumer education offering informations and learing practical ads. discriminatory competencies should be conducted for all consumers wheather they are educated or not. Also the education to improve the consumer attitude must be. Second, considering misleading level, the business must make the regulatory standards and reinforce the regulation voluntarily, and by enforcing the regulation of ads. and deciding more diverse, objective and exact standards, the government should keep the consumer's right to know.

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Polymorphism of Dopamine Transporter Gene(DAT1) in Korean Social Phobia Patients:Preliminary Study (한국인에서의 도파민 수송체 유전자 다형성(Dopamine Transporter Gene(DAT1) Polymorphism)과 사회공포증과의 연관성에 관한 예비 연구)

  • Oh, Kang Seob;Yoon, Hyung Kun;Lee, Min Soo
    • Korean Journal of Biological Psychiatry
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    • v.11 no.2
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    • pp.165-172
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    • 2004
  • Objective:Although polymorphism of dopamine transporter gene(DAT1) has been considered to be implicated in the pathogenesis of social phobia, previous investigations have been inconsistent and controversial. The authors investigated the relationship between DAT1 polymorphism and social phobia in Koreans. Methods:DAT1 and alleles of fifty subjects who met DSM-IV criterion of social phobia, and those of age- & sex- matched fifty normal controls in Korea were compared. Additionally, patients were grouped into generalized(33) and nongeneralized(17) types and DAT1 polymorphism was compared with that of age- & sex- matched controls. DAT1 with variable number of tandem repeats(VNTR) were determined by using polymerase chain reaction. To compare the distribution of the DAT1 polymorphism between different groups, Fisher's exact test was used. Results:There were no significant differences in either genotypic(p=0.451) or allelic(p=0.452) distributions between the social phobia patients and the controls. There also were no differences in genotypic distribution between subtypes of social phobia patients and the controls. Conclusion:We couldn't find any association between DAT1 polymorphism and social phobia. Further studies including larger number of samples and diverse clinical variables should be conducted to elucidate the present findings.

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Estimation of Hydrodynamic Coefficients for AUV-SNUUV I (AW-SNUUV I의 동유체력 계수 추정)

  • Kim Kihun;Kim Joonyoung;Shin Minseop;Choi Hang S.;Seong Woojae
    • Proceedings of the KSME Conference
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    • 2002.08a
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    • pp.201-204
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    • 2002
  • This paper describes the hydrodynamic characteristics of a test-bed AUV SNUUV-I constructed at Seoul National University. The main purpose of the AUV is to carry out fundamental control and hydrodynamic experiments. Its configuration is basically a long cylinder of 1.35m in length and 0.25m in diameter with delta-type wings near its rear end. On the edge of each wing, a thruster of 1/4HP is mounted, which is used for both drive and turn the vehicle for horizontal movement as the output control power is varied. A pair of control surfaces installed near its font part generates pitch moments for vertical movement. The 6 DOF mathematical model of SNUUV-I contains hydrodynamic forces and moments expressed in terms of a set of hydrodynamic coefficients. These coefficients can be classified into linear damping coefficients, linear inertial coefficients and nonlinear damping coefficients. It is important to estimate the exact value of these coefficients to control the vehicle precisely. Among these, the linear coefficients are known to affect the motion of the vehicle dominantly. The linear damping coefficients are estimated by using Extended Kalman Filter. The responses of the vehicle to input signals are used to estimate the hydrodynamic coefficients, which can be inferred from output signals measured from an IMU (inertial motion unit) sensor, while the linear inertial coefficients are calculated by a potential code. By using these coefficients estimated as described above, a simulation program is constructed using Matlab.

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Relation between Location of Pelvic bone Fractures and the Injury to the Urinary bladder, Urethra or Lower gastrointestinal tract (골반 골절 위치와 방광, 요도, 하부 위장관계 손상의 관련성)

  • Kim, Chang Ho;Park, Jung Bae;Ryoo, Hyun Wook;Seo, Kang Suk;Seo, Jun Seok;Chung, Jae Myung;Je, Dong Wook;Sung, Ae Jin
    • Journal of Trauma and Injury
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    • v.20 no.2
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    • pp.90-95
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    • 2007
  • Purpose: This research was conducted to study whether the specific location of pelvic-bone fractures could increase the risk for injury to the urinary bladder, urethra, or lower gastrointestinal tract. Methods: We retrospectively reviewed the data of 234 patients with pelvic-bone fractures who visited the emergency department of Kyungpook National University Hospital from January 2004 to December 2006. The location of the pelvic-bone fracture was divided into 8 parts. The association of fracture location with injury to the urinary bladder, urethra, or lower gastrointestinal tract was analyzed with Fisher' s-exact test and multiple logistic regression. Results: Nineteen(19) patients had urinary bladder injury, 8 had urethral injury, and 9 had lower gastrointestinal tract injury. The following fracture locations were found to be significant; urinary bladder: sacroiliac (SI) joint (p<0.001), symphysis pubis (p=0.011), and sacrum (p=0.005); urethra: SI joint (p=0.020); lower gastrointestinal tract: symphysis pubis (p=0.028). After the multiple logistic regression analysis, the primary and the independent predictors for each of the injuries were as follows; urinary bladder: sacroiliac joint (p=0.000, odds ratio [OR]=10.469); lower gastrointestinal tract: symphysis pubis (p=0.037, OR=7.009). Conclusion: Consideration of further workup for injuries to the lower gastrointestinal and urinary tract is needed for some locations of pelvic-bone fractures because certain pelvic-bone fracture locations, especially the sacroiliac joint and the symphysis pubis, are associated with increased risk for injury to the lower gastrointestinal and urinary tracts.

Equipment for Measuring the Adiabatic Temperature Rise of Concrete by Compensating Heat Loss (열손실량 보정을 통한 콘크리트 단열온도상승량 예측 장치)

  • Jin, Eun-Woong;Kim, Chin-Yong;Kim, Jin-Keun
    • Journal of the Korea Concrete Institute
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    • v.24 no.5
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    • pp.535-542
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    • 2012
  • Adiabatic temperature rise test for predicting heat of hydration in mass concrete is especially inconvenient in the field. In order to overcome the problem, the equipment to effectively and conveniently measure semi-adiabatic temperature change was developed. The main objective of this paper is to propose a new and simple equipment for measuring semi-adiabatic temperature rise by using insulation bottles. In order to predict exact heat loss of concrete using this device, it is required to assume the specific heat loss coefficient of the device by water temperature change inside the experimental device. According to experimental and analytical results, the adiabatic temperature rise does not have significant differences in changes of temperature and humidity of air, as well as initial temperature of water. By comparing adiabatic temperature rise tests, the equipment for measuring semi-adiabatic temperature change can be used to predict the hydration heat of concrete within sufficient accuracy.

Flame and Smoke Detection Method for Early and Real-Time Detection of Tunnel Fire (터널 화재의 실시간 조기 탐지를 위한 화염 및 연기 검출 기법)

  • Lee, Byoung-Moo;Han, Dong-Il
    • Journal of the Institute of Electronics Engineers of Korea SP
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    • v.45 no.4
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    • pp.59-70
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    • 2008
  • In this paper, we proposed image processing technique for automatic real-time fire and smoke detection in tunnel environment. To avoid the large scale of damage of fire occurred in variety environments, it is purposeful to propose many studies to minimize and to discover the incident as fast as possible. But we need new specific algorithm because tunnel environment is quite different and it is difficult to apply previous fire detection algorithm to tunnel environment. Therefore, in this paper, we proposed specific algorithm which can be applied in tunnel environment. To minimize false detection in tunnel we used color and motion information. And it is possible to detect exact position in early stage with detection, test, verification procedures. In addition, by comparing properties of each algorithm throughout experiment, we have proved the validity and efficiency of proposed algorithm.

How to Improve Patients' Satisfaction in Healthcare Organization? - Healthcare Service Quality Classification using Kano Model - (의료기관의 소비자 만족도 향상요소 도출 - Kano 모형에 기반한 의료서비스 품질 분류를 중심으로 -)

  • Paik, Hye-Ran;Kim, Kwang-Jum
    • Korea Journal of Hospital Management
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    • v.19 no.2
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    • pp.73-88
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    • 2014
  • Objective: This research investigates how to increase the quality of medical service and supply high quality of medical service to patients. By using Kano Model theory we examines what medical service attributes the hospital would be conducted preferentially for patient's satisfaction and provides informations of management strategies for hospitals. Method: To study patients' perception of medical service quality, first we performed pilot test to derive 30 medical service attributes. With 30 medical service attributes, we conducted survey of 300 subjects who have experienced medical services in 6 months. To examine patients' conception of medical services, a modified Kano's questionnaire using 5 scale is applied. Finally we calculated SI(Satisfaction index) and DI(Dissatisfaction index) and PCSI(Potential Customer Satisfaction Improvement) index with Kano's Model analysis results. Key Findings: We found that the quality of medical service categorized in 15 one-dimensional elements, 9 must-be elements and 6 indifferent elements. Moreover the attribute of gives prompt services and have patient's best interest at heart scored the highest SI, whereas the attributes of accurate and precise medical service, exact records, enough explanation and polite attitudes are the highest score of DI. And also good explanation of the bill scored the highest PCSI. In this study findings indicate that while medical service providers try to increase patients' satisfaction by improving hospital's environments, patients' perception of trust and good interpersonal relationships with medical service providers have strong and positive impact on patients' satisfaction.

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Risk Factors Affecting Recurrence of Thyroglossal Duct Cyst in Children (소아에서 발생한 갑상설관낭종의 재발에 영향을 미치는 위험인자)

  • Jung, Hee-Kyung;Park, Jin-Young
    • Advances in pediatric surgery
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    • v.17 no.1
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    • pp.35-44
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    • 2011
  • Thyroglossal duct cysts (TGDC) are the most common type of congenital developmental anomaly encountered in the anterior midline of the neck in childhood. The aim of the study was to evaluate the clinical characteristics of TGDC and identify any factors that could be related to recurrence after surgery. This study consisted of a retrospective chart review of 45 patients treated at Kyungpook National University Hospital for TGDC between 1990 and 2008. All records were reviewed for age and sex, length of history, presentation, diagnostic methods, sizes and locations of cyst, surgical management, histopathology of the lesion and recurrences. The statistical analysis of risk factors for recurrence was made using the Fisher's exact test with a significance level of p (0.05. The male to female ratio was 2.2:1 with a male preponderance. The mean age at operation was 5 years and 2 months (4 months - 17 years). The most common presenting symptom was a nontender cervical mass (78 %). Most TGDC were found in the midline position. Twenty four were infrahyold, 17 were hyoid, and 4 were suprahyoid level. Forty one (91 %) patients received the Sistrunk operation, and 4(9 %) patients received Cyst excision. Postoperative a seroma developed in six patients in the early postoperative days. There were a total of 3(6.6 %) recurrences, 2 in patients who had excision only and in one patient who had the Sistrunk operation. Univariate analysis for risk factors with recurrence showed that there was no statistical relationship between the presence of preoperative infection and the development of recurrence. The removal of hyoid bone along with TGDC was a statistically significant risk factor for recurrent disease. This study suggests that the Sistrunk operation Is the treatment of choice for TGDC in order to reduce recurrence.

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Clinicopathological Features of Adrenal Tumors: a Ten-year Study in Yazd, Iran

  • Zahir, Shokouh Taghipour;Aalipour, Ezatollah;Barand, Poorya;Kaboodsaz, Mansoureh
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.12
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    • pp.5031-5036
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    • 2015
  • Background: Adrenal tumors are relatively uncommon, and have different presentations, so we decided to evaluate the clinico-pathological characteristics of benign and malignant tumors in a ten-year period. Materials and Methods: This cross sectional-analytical study was conducted on adrenal resection samples taken during 2004-2014 in three hospitals in Yazd province. Data were analyzed using SPSS software, version 17. Chi-square and Fisher's exact test were used as appropriate Results: A total of 71 patients with adrenal tumors were analyzed, including 32 (45.1%) men and 39 (54.9%) women with an overall mean age $37.7{\pm}19.9$ (range: 6-75 years). Some 50.7% of lesions were benign and 49.3% were malignant. Neuroblastoma was the most malignant lesion (32.3%) followed by adrenocortical carcinoma (8.4%). Among the benign lesions pheochromocytoma was the most common (25.3%) followed by adrenocortical adenoma (12.6%). While 64% of tumors were functional 36% were non functional. Significant correlation was seen between the age of patient and type of tumor (P=0.001). In patients between 14-40 years old no malignant lesions was found, although under 14 years old all of the tumors were malignant. Malignant lesions mostly presented with abdominal pain, abdominal mass and anorexia (57.2%, 45.7% and 45.7%) respectively. Benign lesions mostly presented with paroxysmal hypertension, headache and abdominal pain (61.2%, 47.2% and 44.4%) respectively. Conclusions: Since the trend of adrenal tumors is on the rise based on this and other studies, suspected cases should undergo prompt hormonal and radiological assessment. Early diagnosis and treatment could prevent tumor progression and reduce mortality and morbidity rates.