• Annals of Clinical Neurophysiology
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• 제8권2호
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• pp.107-124
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• 2006

The basal ganglia are a group of nuclei located in the deep portion of the brain. Along with the cerebellum, the basal ganglia have a major role in controlling human voluntary movements, and their dysfunction is apparently responsible for various involuntary movements. Although the exact mechanism of how the basal ganglia control movements has yet to be clarified, the model of focused selection (through the direct pathway) and tonic inhibition (via the indirect pathway) is proposed to be a principal functional model of the basal ganglia. Parkinson's disease (PD) is classically characterized by bradykinesia, rigidity and tremor-at-rest. All features seem to be associated with dopamine depletion resulting from the degeneration of the nigrostriatal pathway, which produces reduced activity of the direct pathway and a concurrent enhancement of excitatory output from STN. This change may result in increased tonic background inhibition and reduced focused selection via the direct pathway, causing difficulties in performing voluntary movements selectively. However, it has not been possible to define a single underlying pathophysiologic mechanism that explains all parkinsonian symptoms. Here the data that give separate understanding to each of the three classic features are discussed.

• 한국구조물진단유지관리공학회 논문집
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• 제18권3호
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• pp.10-19
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• 2014

파형강판은 제형, 정현형 등의 형상으로 얇은 강판을 주름지게 가공한 것으로 두꺼운 평판을 대신하여 사용하여도 높은 면외방향의 강성을 확보할 수 있다. 또한, 아코디언효과로 축방향 강성이 거의 없어 플레이트거더의 웨브에 적용할 경우 웨브가 전단력만을 부담하는 방법으로 쉽게 설계할 수 있다. 그러나 파형강판의 전단좌굴은 평판과는 달리 국부좌굴과 전체좌굴 외에도 이들의 연성에 의해서도 좌굴이 발생하는 매우 복잡한 특성이 있으며, 이러한 연성좌굴에 대한 원인과 특성의 규명은 정현형의 경우 제형보다 연구결과가 부족한 실정이다. 따라서 본 연구에서는 정현형 파형강판의 전단좌굴 특성과 연성좌굴이 발생하는 경향에 대해서 연구하였다. 전단좌굴강도를 계산하기 위해서는 유한요소프로그램을 이용하였고 해석결과를 정해와 비교하였다. 또한, 주름의 두께와 형상 파라메타에 따른 좌굴응력 변화의 특성과 좌굴모드형상의 변화를 분석하였으며, 이들의 결과를 이론식의 결과와 비교하여 좌굴양상의 변화시점에 대해서 분석하였다.

• Structural Engineering and Mechanics
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• 제32권3호
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• pp.383-398
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• 2009

Applying nonlinear statistical analysis methods in estimating the performance of structures in earthquakes is strongly considered these days. This is due to the methods' simplicity, timely lower cost and reliable estimation in seismic responses in comparison with time-history nonlinear dynamic analysis. Among nonlinear methods, simplified to be incorporated in the future guidelines, Modal Pushover Analysis, known by the abbreviated name of MPA, simply models nonlinear behavior of structures; and presents a very proper estimation of nonlinear dynamic analysis using lateral load pattern appropriate to the mass. Mostly, two kinds of connecting joints, 'hinge' and 'rigid', are carried out in different type of steel structures. However, it should be highly considered that nominal hinge joints usually experience some percentages of fixity and nominal rigid connections do not employ totally rigid. Therefore, concerning the importance of these structures and the significant flexibility effect of connections on force distribution and elements deformation, these connections can be considered as semi-rigid with various percentages of fixity. Since it seems, the application and implementation of MPA method has not been studied on moment-resistant steel frames with semi rigid connections, this research focuses on this topic and issue. In this regard several rigid and semi-rigid steel bending frames with different percentages of fixity are selected. The structural design is performed based on weak beam and strong column. Followed by that, the MPA method is used as an approximated method and Nonlinear Response History Analysis (NL-RHA) as the exact one. Studying the performance of semi-rigid frames in height shows that MPA technique offers reasonably reliable results in these frames. The methods accuracy seems to decrease, when the number of stories increases and does decrease in correlation with the semi-rigidity percentages. This generally implies that the method can be used as a proper device in seismic estimation of different types of low and mid-rise buildings with semi-rigid connections.

• 대한족부족관절학회지
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• 제9권1호
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• pp.99-104
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• 2005

Purpose: The purpose of this study was to investigate usefulness of locking compression plate (LCP) as an open reduction technique by evaluating clinical results obtained from the patients with lateral malleolar fracture treated by internal fixation using LCP after open reduction. Materials and Methods: Among the patients with lateral malleolar fracture, the 28 patients who were treated by internal fixation using Locking compression plate after an open reduction and were able to be followed up for more than 6 months were included in this study. Final postoperative evaluation was done based on the Meyer's clinical and radiologic evaluation system. Results: All cases achieved anatomical reduction and fixation of the reduction postoperatively. 28 minutes were taken meaningly from the incision to the fixation of LCP plate after the anatomical reduction. Everage bony union time was 8.2 weaks, and the result was excellent in 23 cases (82%), good in 5 cases (17%) and poor result was abscent according to the criteria of Meyer et al. One case of post traumatic arthritis and one case of superficial infection on the operation site were found, but non-union, delayed union and malunion were not occurred. Conclusion: The internal fixation after open reduction using LCP is an effective treatment method in treating lateral malleolar fracture of the ankle since it offers advantages including easy application and a greater stability due to its capability of maintaining exact anatomical reduction even though the screw does not penetrate the medial cortex of fibular to add the stability and rigidity of the fixation.

• 한국강구조학회 논문집
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• 제16권5호통권72호
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• pp.671-682
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• 2004

본 연구는 부분 전단연결을 가지는 강-콘크리트 합성보의 처짐에 미치는 전단슬립의 영향을 조사하는 것이다. 현재 각국의 설계규준에서는 합성보의 처짐 계산시 전단연결재의 강도와 관련되어 있지만, 본 연구에서는 하중조건에 상관없는 전단연결재의 강성에 기반을 둔 정확한 해를 유도하였다. 우선, 평형조건, 곡률의 적합조건에 기반을 둔 3가지 하중조건에서의 합성보의 등가강성을 유도하고, 이로부터 하중조건에 상관없이 슬립의 영향을 적용할 수 있는 간편한 제안식을 유도하였다. 이러한 제안식의 타당성을 검증하기 위해서 현재 AISC에서 사용하고 있는 합성보의 유효강성 및 Nie가 제안한 식과 비교하였다. 일반적으로 사용되는 보의 경우, 전단슬립의 영향은 스팬이 짧을 경우, AISC에 비해서 최대 18%까지의 강성의 감소를 나타냄을 알 수 있었다. 완전합성보의 경우, AISC의 제안 값이 본 연구의 결과 보다 크게 나타났는데, 이는 안전측이 되지 못함을 알 수 있었으며, 불완전 합성보의 경우, AISC 제안식이 본 연구보다 강성을 과소 평가하는 결과를 나타내었다.

• 고려인삼학회:학술대회논문집
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• 고려인삼학회 1998년도 Advances in Ginseng Research - Proceedings of the 7th International Symposium on Ginseng -
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• pp.208-215
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• 1998

Ginseng has been used in maintaining physical vitality all over the East Asian countries and recently its metabolism and actions on neurologic, cardiovascular and endocrinologic systems are being elucidated. Korean red ginseng (KRG) has been used in various aliments, and to prove its efficacy icy erectile dysfunction an international study on Asians other than Korean was performed. Patients with borderline organic and psychogenic erectile dysfunction were included. KRG were given daily, and placebos were given as controls. Treatment lasted a total of 3 months. Surveys including libido, erectile potency, the sexual satisfactions were given. Serum testosterone and erectile function study were taken. Among the 23 patients with KRG, 18 patients were followed. Four had diabetes, 2 hypertension, 3 hyperchole, iterolemia, 1 low testosterone,4 psychogenic, and 4 idiopathic. In 10 patients with placebo, 7 were followed for more than three months. The clinical efficacy of KRG was 66.7% on objective Questionnaire and 72.2% on subjective analysis. When KRG were given, all parameters surveyed have shown improvements compared to the controls. Serum testosterone Bevels were normalized in 2 patients with KRG, whose serum testosterone levels were reduced from prestudy. When the erectile functions after audiovisual stimuli evaluated using Rigiscan in 6 patients with KRG,4 showed rigidity move than 70oyc. One patient reported constipation, and 2 gastric up-sets in the KRG group. In conclusion, KRG has beneficiary action on male erectile capabilities with minimal side effects. Thus KRG has been proven effective in Koreans, and a result on other Asians is pending. The exact action mechanism and the active ingredients in KRC need to be itudied.

• 대한토목학회논문집
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• 제33권2호
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• pp.409-422
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• 2013

부재간의 연결조건에 따른 다양하고 복잡한 강구조물의 P-${\Delta}$ 해석 및 좌굴 거동특성을 파악하기 위하여, 본 연구에서는 부재의 연결이 회전 및 이동스프링으로 구성된 부분강절(semi-rigid) 뼈대요소의 일반화된 접선강도 행렬을 유도하였고 이로부터 다시 Taylor 전개를 적용하여 탄성강도 행렬과 기하학적 강도행렬을 일반화된 형태로 제시하였다. 이를 위하여, 보-기둥부재의 좌굴조건을 만족시키는 처짐함수로부터 안정함수(stability function)를 유도하였고, 횡변위(sway)를 고려한 힘-변위관계와 적합조건을 고려하여 엄밀한 부분강절 뼈대요소의 접선강도행렬을 제시하였다. 다양한 수치해석 예제에 대해 타 연구자의 해석 결과 및 본 연구의 선형 및 비선형 해석이론을 통한 좌굴해석 결과를 비교하여 본 연구의 타당성과 부분강절 뼈대구조물의 좌굴거동 특성을 제시하였다.

• 한국동물위생학회지
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• 제46권1호
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• pp.87-92
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• 2023

A 7-year-old dog weighing 3.9 kg visited the hospital with symptoms of inability to stand and quadriparesis. There were seizure symptoms 2 months before admission to the hospital, and the symptoms of stiffness and rigidity appeared. Radiographs showed normal vertebrae in cervical vertebral column. Magnetic resonance imaging (MRI) and computed tomography (CT) were performed immediately to diagnose vertebral lameness. As a result of the CT, it was possible to observe the fracture of the odontoid process of the axis, and the exact location of the damage was identified. The odontoid process was fractured and separated from the body of the 2^nd cervical vertebra (axis), and fragment of the process was observed inside the vertebral arch of the first cervical vertebra (atlas), and the body of the axis was lifted to the dorsal side. The MRI examination reflected the CT findings and confirmed severe spinal cord compression due to the fracture of the odontoid process. The patient was applied by neck brace and medical management including Mycophenolate mofetil administration was performed. The patient was able to move legs and tail after 2 weeks, and was able to voluntarily defecate, urinate and stand up after 4 weeks of administration.

• 한국지구물리탐사학회:학술대회논문집
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• 한국지구물리탐사학회 2004년도 정기총회 및 제6최 특별 심포지움
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• pp.25-48
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• 2004

구조물의 시간경과에 따른 변형 및 성능저하 현상은 인위적 요인 및 시간경과에 따른 지반상태의 변화 혹은 지반 변위요인의 누적에 의해 발생한다. 본 연구에서는 경상남도 경주시에 위치한 첨성대를 연구대상으로 설정하였다. 첨성대는 약 1,300여 년 전 건립된 석축구조물로서 지반침하로 약간 기울어져 있으며, 일부 석재 사이의 틈이 벌어져 있는 상태이다. 본질적인 대책수립을 위하여 본 연구에서는 이러한 목적을 위하여 3차원 레이저스캐닝시스템에 의한 (형상)역공학적 연구, 물리탐사에 의한 지반공학적 특성 연구 및 고유진동수 측정에 의한 첨성대의 동적특성 등의 다음과 같은 연구들을 수행하였다. 첫째, 정밀측량에 의한 첨성대의 정밀한 변형량 측정 및 지속적인 변위측정을 위하여 3차원 레이저 스캐닝에 의한 첨성대의 3차원 공간위치정보를 취득하여 형상역공학에 의한 3차원 벡터이미지 형상구현 및 첨성대의 크기, 변위량, 변위방향 등 여러 가지 제원을 구하고자 하였다. 둘째, 다양한 비파괴적 물리탐사 방법들을 적용하여 첨성대 및 주변 지반의 물성분포 및 지반특성을 파악하고자 하였다. 한편, 다양한 물리탐사를 통하여 향후 유사한 조사에 있어서 적절한 물리탐사 방법을 제시하고자 하였다. 셋째, 경주 첨성대의 1/10 모형에 대한 동적특성실험 및 실물에 대한 고유진동수 측정을 통해 첨성대의 구조적 특성을 연구하여 첨성대의 구조특성 및 상태판단 및 동적특성 파악에 의한 내진성능을 판단하고자 하였다.