• Journal of Microbiology and Biotechnology
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• v.1 no.1
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• pp.50-53
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• 1991

The reaction steps involved in the bioconversion of a chemically synthesized precursor, $D,L-2-amino-{\Delta}^2-thiazoline-4-carboxylic$ acid (D,L-ATC), to L-cysteine and the properties of the involved enzymes were investigated. It was found that the conversion consisted of two steps, i. e., D,L-ATC to S-carbamyl-L-cysteine (S-C-L-cysteine) and S-C-L-cysteine to L-cysteine, and the S-C-L-cysteine was an intermediate between them. While the enzymes involved in the reactions were induced by the addition of D,L-ATC as an inducer, S-C-L-cysteine induced only the enzyme involved in the latter step. The conversion of S-C-L-cysteine to L-cysteine could be also carried out in the presence of hydroxylamine and its rate was much faster than that by the corresponding enzyme. On the other hand, L-cysteine (or L-cystine) was decomposed to evolve $H_2S$ by the enzyme considered to be a kind of desulfhydrase. However, hydroxylamine was a perfect inhibitor for this enzyme.

• Journal of the Korean Society for Aviation and Aeronautics
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• v.25 no.3
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• pp.1-8
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• 2017

As many people all over the world increasingly take more time in exchanging with other people or acquiring information on the internet, use of social media becomes a part of their daily lives. A lot of changes of consumer culture, which have been occurring through social media, have significant effects on corporate marketing activities. Since social media's importance to airlines has been continuously increased, this study attempts to examine effects of passengers' uses of social media, who plan to select an airline, on dependence on reliance of electronic word-of mouth(EWOM) and EWOM acceptance. To this end, a questionnaire survey of passengers who use airlines and the airline's social media was conducted, and then effective data of 302 copies were analyzed by using the structural equation modeling. The findings show that social media use intensity has a significant effect on Acceptance of EWOM via reliance of EWOM, while a direct effect of social media use intensity on Acceptance of EWOM is not significant. From this study, it is found that control and management of social media and only EWOM are effective tools for marketing of airline businesses, suggesting that innovative strategies are required to preemptively cope with changes in consumers' behaviors and markets, which continue to evolve.

• Archives of design research
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• v.15 no.4
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• pp.15-24
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• 2002

Today, as era of Internet competition, experimental magazines-created especially for young adult group-are also trying to convert themselves into a internet magazines. This study intends to find out contents format and visual expression that should be considered for on-line conversion of these magazines. The industry's leading experimental magazines, for example, 'ttl', 'Paper', and 'webzine sponge' which co-exist in both printed and web-based format are to be examined by their contents, typography, colors, pictures& illustrations and others. This study intends to exam and suggest possible contents format and visual expression which they ought to evolve with.

• Archives of design research
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• v.5 no.1
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• pp.37-44
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• 1992

Today, the art and the architecture face up to the problem of loss of direction. So, the derection of post have been lost. This phenomina cause the second loss of direction, because the mode of pre-modernism is underestimated. After all, the mode and philosophy of after-modernism face up to the new crisis of derection. Present artists, archtectures and designers have to acnieve new trial and study for estimation of aestetics and directions. Ultimately, constant exercise and study of philosophy, morpholophy, morphology, current mode and new materials is necessary to search a methodology. This all have to be accomplished by the clear philosophy. The original identity is formed in environmental basis. So, first, architectures, designers, and artist understand native identity, second, we sho have acadenical and practical faculties impose significance. In case of Europe, the change of mode have led paradigm of culture. The great change of social culture have come out the wave of revolution that cross in design, architecture and art. 1920's of modernism evolve 1960's completion. In the change of life style, functionalism have evolved postmodernnism. But, in this change we do not suggest the new derection that form concrete idea and sympathy. This phenomina appear in the end of a centry, and nowaday is that day. This trends effect on artists, architectures, and designers, and design and will be changed. Finally, we need to study of concrete and new direction in this circumstance.

• Journal of the Korea Computer Industry Society
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• v.2 no.10
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• pp.1309-1316
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• 2001

In the majority of todays animation and computer games, the behaviours of characters are controlled by pre-defined game logic or pre-generated motion. As game developers strive for richer and more interactive games, they often encounter limitations with this approach. This paper attempts to construct a game model using Genetic Algorithms (GAs) in order to produce more intelligent and compelling computer games. Based on learning ability, the use of GAs will enable the characters to continually evolve, providing a changing and dynamic game environment. A real-time game was implemented to investigate the performance and limitations of the system.

• Journal of the Korean Society of Systems Engineering
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• v.7 no.1
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• pp.31-41
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• 2011

The purpose of this paper is to provide an abstracted meta-model for executing Capabilities Portfolio Management (CPM) effectively based on DoDAF2.0. The purpose of developing an architecture is for beneficial use of it. A good set of architectural artifacts facilitates the manipulation and use of them in meeting its usage objectives well. Systems engineering methodologies evolve to accommodate or to deal with enterprise or SoS/FoS level problems. And DoD's Capabilities Portfolio Management (CPM) is a good example which demonstrates enterprise or SoS level problems. However, the complexity of the architecture framework makes it difficult to develop and use the architecture models and their associated artifacts. DoDAF states that it was established to guide the development of architectures and to satisfy the demands of a structured, repeatable method for evaluating alternatives which add value to decisions and management practices. One of the objectives of DoDAF2.0 is to define concepts and models usable in CPM which is one of DoD's six core processes. However, DoDAF and various guidelines state requirements for CPM rather than how to. This paper provides methodology for CPM which includes process and tailored meta-models based on DoDAF Meta Model (DM2).

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.6
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• pp.2145-2150
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• 2015

HPV viruses are integral to the development of cervical cancer. The pathogenesis has been extensively studied. To date, numerous HPV tests and products have been developed and successfully utilized in diagnosis, treatment and prevention of cervical cancer. The HPV DNA test, when combined with other routine cervical cancer screening and diagnostic tests namely exfoliative cytology, visual inspection with acetic acid (VIA) and colposcopy has increased the detection rate of cervical cancer. HPV DNA products could also be measured in other body fluids like urine, lymph node tissue, and serum. HPV association could also be quantified by measuring other parameters like HPV mRNA, viral load, viral integration and methylation status. Vaccination against HPV has been found to decrease the incidence of cervical cancer. Further, therapeutic vaccines for cervical cancer against HPV continue to evolve. All these findings pertaining to HPV could possibly decrease the incidence of cervical cancer in the near future. This review aims to give an overview of the HPV tests and products in use and those under trial currently.

• Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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• v.15 no.4
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• pp.301-312
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• 2017

The concept of deep borehole disposal (DBD) for high-level nuclear wastes has been around for about 40 years. Now, the Department of Energy (DOE) in the United States (U.S.) is re-examining this concept through recent studies at Sandia National Laboratory and a field test. With DBD, nuclear waste will be emplaced in boreholes at depths of 3 to 5 km in crystalline basement rocks. Thinking is that these settings will provide nearly intact rock and fluid density stratification, which together should act as a robust geologic barrier, requiring only minimal performance from the engineered components. The Nuclear Waste Technical Review Board (NWTRB) has raised concerns that the deep subsurface is more complicated, leading to science, engineering, and safety issues. However, given time and resources, DBD will evolve substantially in the ability to drill deep holes and make measurements there. A leap forward in technology for drilling could lead to other exciting geological applications. Possible innovations might include deep robotic mining, deep energy production, or crustal sequestration of $CO_2$, and new ideas for nuclear waste disposal. Novel technologies could be explored by Korean geologists through simple proof-of-concept experiments and technology demonstrations.

• Journal of Korean Library and Information Science Society
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• v.39 no.2
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• pp.169-186
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• 2008

Social Network has been known as friendship basis human relation service in online network. But a broad sense of Social Network can be explained as a mechanism which makes web evolve to information-ecosystem by human relation and network data which has been generated by the mass of people's cooperation and interchange. Social Network has been expanding their domain from friendship basis relation service to broad social relationship focus of matter of concern. It has been applied to diverse domain. Library community begins to take an interest in Social Network concept to apply user's interchange for information. This paper considers the concept of Social network and it's appliance to a library service. For the more, suggest basic element for vitalizing library user's Social network.

• Microbiology and Biotechnology Letters
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• v.36 no.2
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• pp.149-157
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• 2008

Many proteins consist of distinctive domains that can act independently or cooperatively to achieve a unique function. As these domains evolve from a naturally existing repertoire of functional domains, this implies that domain organization is an intrinsic element involved in building the complex structure and function of proteins. Thus, identifying functional domains would appear to be critical to the elucidation of questions related to protein evolution, folding, and the engineering of hybrid proteins for tai- lored applications. However, the simple application of "Lego-like assembly" to the engineering of hybrid proteins is an oversimplification, as many hybrid constructs lack structural stability, usually due to unfavorable domain contacts. Thus, directed evolution, along with computational studies, may help to engineer hybrid proteins with improved physico-chemical properties. Accordingly, this paper introduces several approaches to functional hybrid protein engineering that potentially can be used to create modulators of gene transcription and cell signaling, and novel biosensors to analyze biological functions in vivo.