• 한국정보과학회논문지:데이타베이스
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• 제31권5호
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• pp.445-456
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• 2004

데이타베이스 스키마는 모델링 되는 환경이 변화할 때에도 여전히 유효한 상태로 남을 만큼 안정적이라고 가정되어 왔다. 그러나 실제로는, 데이타 모델은 데이타베이스 설계자들이 공통으로 가정하는 만큼 안정적이지 않다. 현재 데이타베이스 시스템에서 풍부한 스키마 변화 연산들이 제공되지만은 사용자들은 스키마 변화가 스키마에 쓰여진 기존의 응용 프로그램에 영향을 미치는 문제로 곤란을 겪어왔다. 이 논문은 응용 프로그램에 영향을 주는 문제를 탐구한다. 옛 스키마에 기존의 프로그램을 지속적으로 지원하기 위하여 옛 스키마가 이전처럼 변경과 질의를 계속 허락해야 한다. 더 나아가, 관련 데이타는 최신상태로 유지되어야 한다 이것을 스키마 변화 도구의 프로그램 독립 성질이라 부른다. 이 성질을 달성하기 위하여, 이 논문은 프로그램 독립적인 스키마 진화 (Program Independency Schema Evolution: PISE) 방법론을 제안한다. 더 나아가, 각각의 관계형 스키마의 변화 연산들에 대하여 PISE 방법론에 기초한 구현 알고리즘을 도식적으로 설명함으로써 PISE 방법론의 포괄성과 견고성을 증명한다.

• Journal of Information Science Theory and Practice
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• 제2권3호
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• pp.40-54
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• 2014

This paper attempts to highlight quantitatively the growth and development of literature in the field of ecology in terms of publication output using the resource Web of Science$^{(R)}$. The focus of this analysis was to study the literature on ecology published in three journals, viz., Ecology Letters, Trends in Ecology & Evolution, and Annual Review of Ecology Evolution and Systematics. 2946 records were retrieved for 10 years (2003-2012). The study revealed that multiple authorship in the field with collaborations of two (30.31%) and three authors (19.89%) was dominant. The Degree of collaboration, Collaborative coefficient, and Collaborative index were calculated and the applicability of Lotka's law was tested. The study identified five-year patterns in research trends, using the three studied journals, to see if the subjects of focus changed within a decade. The most productive institution was University Calif. Davis, USA, followed by University Calif. Santa Barbara, USA, and University Queensland, Australia, and the most productive countries were the USA followed by UK and Canada.

• Journal of Astronomy and Space Sciences
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• 제38권1호
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• pp.65-82
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• 2021

For the vast majority of geostationary satellites currently in orbit, station keeping activities including orbit determination and maneuver planning and execution are ground-directed and dependent on the availability of ground-based satellite control personnel and facilities. However, a requirement linked to satellite autonomy and survivability in cases of interrupted ground support is often one of the stipulated provisions on the satellite platform design. It is especially important for a geostationary military-purposed satellite to remain within its designated orbital window, in order to provide reliable uninterrupted telecommunications services, in the absence of ground-based resources due to warfare or other disasters. In this paper we investigate factors affecting the robustness of a geostationary satellite's orbit in terms of the maximum duration the satellite's station keeping window can be maintained without ground intervention. By comparing simulations of orbit evolution, given different initial conditions and operations strategies, a variation of parameters study has been performed and we have analyzed which factors the duration is most sensitive to. This also provides valuable insights into which factors may be worth controlling by a military or civilian geostationary satellite operator. Our simulations show that the most beneficial factor for maximizing the time a satellite will remain in the station keeping window is the operational practice of pre-emptively loading East-West station keeping maneuvers for automatic execution on board the satellite should ground control capability be lost. The second most beneficial factor is using short station keeping maneuver cycle durations.

• 인터넷정보학회논문지
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• 제13권4호
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• pp.53-62
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• 2012

객체분할은 영상처리와 컴퓨터비전분야의 상당히 어려운 연구대상이다. 그레이스케일 영상에 대한 영상분할은 매우 많은 방법이 발표되었으며 다양한 영상특징과 처리방법이 제시되었다. 이러한 방법들은 대개 자연상태의 칼라 영상에 적용되기 어렵다. 본 논문에서는 기하학적인 Active Contour 모델의 수정된 형태, 즉 거리정규화레벨셋(distance regularized level set evolution: DRLSE)을 이용한 방법을 제시하여 스피드 함수가 이러한 칼라요소를 반영하도록 하였으며 실험결과 정확성과 시간효율성에 있어서 우수한 결과를 보여주었다.

• BMB Reports
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• 제36권1호
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• pp.78-81
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• 2003

The prevention of cancer is one of the most important public health and medical practices of the $21^{st}$ century. We have made much progress in this new emerging field, but so much remains to be accomplished before widespread use and practice become common place. Cancer chemoprevention encompasses the concepts of inhibition, reversal, and retardation of the cancer process. This process, called carcinogenesis, requires 20-40 years to reach the endpoint called invasive cancer. It typically follows multiple, diverse and complex pathways in a stochastic process of clonal evolution. These pathways appear amenable to inhibition, reversal or retardation at various points. We must therefore identify key pathways in the evolution of the cancer cell that can be exploited to prevent this carcinogenesis process. Basic research is identifying many genetic lesions and epigenetic processes associated with the progression of precancer to invasive disease. Many of these early precancerous lesions favor cell division over quiescence and protect cells against apoptosis when signals are present. Many oncogenes are active during early development and are reactivated in adulthood by aberrant gene promoting errors. Normal regulatory genes are mutated, making them insensitive to normal regulatory signals. Tumor suppressor genes are deleted or mutated rendering them inactive. Thus there is a wide range of defects in cellular machinery which can lead to evolution of the cancer phenotype. Mistakes may not have to appear in a certain order for cells to progress along the cancer pathway. To conquer this diverse disease, we must attack multiple key pathways at once for a predetermined period of time. Thus, agent combination prevention strategies are essential to decrease cancer morbidity. Furthermore, each cancer type may require custom combination of prevention strategies to be successful.

• Clinical and Experimental Pediatrics
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• 제63권6호
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• pp.195-202
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• 2020

Developments in next-generation sequencing (NGS) techogies have assisted in clarifying the diagnosis and treatment of developmental delay/intellectual disability (DD/ID) via molecular genetic testing. Advances in DNA sequencing technology have not only allowed the evolution of targeted panels but also, and more currently enabled genome-wide analyses to progress from research era to clinical practice. Broad acceptance of accuracy-guided targeted gene panel, whole-exome sequencing (WES), and whole-genome sequencing (WGS) for DD/ID need prospective analyses of the increasing cost-effectiveness versus conventional genetic testing. Choosing the appropriate sequencing method requires individual planning. Data are required to guide best-practice recommendations for genomic testing, regarding various clinical phenotypes in an etiologic approach. Targeted panel testing may be recommended as a firsttier testing approach for children with DD/ID. Family-based trio testing by WES/WGS can be used as a second test for DD/ID in undiagnosed children who previously tested negative on a targeted panel. The role of NGS in molecular diagnostics, treatment, prediction of prognosis will continue to increase further in the coming years. Given the rapid pace of changes in the past 10 years, all medical providers should be aware of the changes in the transformative genetics field.

• Journal of Acupuncture Research
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• 제35권2호
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• pp.47-51
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• 2018

Acupuncture is a complex intervention that manifests varied theories, treatment methods, diagnostic methods and diagnostic patterns. Traditionally based systems of acupuncture (TBSAs) often have their own diagnostic approaches and patterns. Despite the wide variety that can be found amongst TBSAs, is it possible that they share a common background in clinical observation and practice? Research has shown that multiple physiological pathways and mechanisms can be triggered by different acupuncture techniques and methods. It is highly likely that clinicians will have observed some of the effects of these responses and used those observations as feedback to help construct the patterns of diagnosis and their associated treatments. This review briefly examines this possibility. Pattern identification will have developed out of a complex interaction of factors that include; theories current at the time of their development, historical theories, personal choices and beliefs, training, practice methods, clinical observations and the natural feedback that comes from observing how things change once the treatment is applied. Researchers investigating TBSAs and pattern identification need to be more explicit about the systems they have investigated in order to understand the biological basis of pattern identification and their treatments.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제40권2호
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• pp.50-60
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• 2014

Tooth loss is very a very common problem; therefore, the use of dental implants is also a common practice. Although research on dental implant designs, materials and techniques has increased in the past few years and is expected to expand in the future, there is still a lot of work involved in the use of better biomaterials, implant design, surface modification and functionalization of surfaces to improve the long-term outcomes of the treatment. This paper provides a brief history and evolution of dental implants. It also describes the types of implants that have been developed, and the parameters that are presently used in the design of dental implants. Finally, it describes the trends that are employed to improve dental implant surfaces, and current technologies used for the analysis and design of the implants.

• Journal of Information Science Theory and Practice
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• 제1권2호
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• pp.6-15
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• 2013

Dr. Ranganathan's "Principles for Helpful Sequence" among the set of normative principles play an exclusive role in the arrangement of subject isolates. Each subject in the universe of subjects is regulated by a guiding principle of its own which analogously determines the sequence of Arrays in ordering the subject surrogates or isolates. For example, the "Principle of Later-in-Evolution" is applied for sequencing isolates of Animal and Plant Species; this concept can be applied to one of the tools of KOS viz. Taxonomies. The application of Principles for Helpful Sequence is summarily presented and in the process the paper highlights the inherent elements of knowledge organization in each one of these principles in a manner that might map the future course of research in this area with the potentiality to bring about a relation between principles for helpful sequence and KOS.

• 한국수학교육학회지시리즈E:수학교육논문집
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• 제18권2호
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• pp.9-33
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• 2004

The purpose of this paper is to contribute to the dialogue about the notion of advanced mathematical thinking by offering an alternative characterization for this idea, namely advancing mathematical activity. We use the term advancing (versus advanced) because we emphasize the progression and evolution of students' reasoning in relation to their previous activity. We also use the term activity, rather than thinking. This shift in language reflects our characterization of progression in mathematical thinking as acts of participation in a variety of different socially or culturally situated mathematical practices. We emphasize for these practices the changing nature of student' mathematical activity and frame the process of progression in terms of multiple layers of horizontal and vertical mathematizing.