• 제목/요약/키워드: Evidence Combination

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How Korean Retailers Expand Private Label Markets Abroad: Evidence from the Chinese Fresh Food Market

  • Jing-Jing Yang;Tae-Won Kang
    • Journal of Korea Trade
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    • 제26권5호
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    • pp.106-124
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    • 2022
  • Purpose - The increasing share of Korean private label products (PLPs) in the domestic market helped generate lucrative revenue. In recent years, major South Korean retailers have begun to cast their sights on overseas markets and actively export their PLPs. In China, the proportion of private label fresh food (PLFF) is gradually expanding amid the development of the new retailing model. A profound understanding of the relationship between private label fresh produce and purchase intention may be the answer to helping Chinese retailer private labels expand supply chains in Korea. This study, taking Chinese retailers as an example, examines the impacts of selection factors of private label fresh food and perceived value on purchase intention. Apart from that, the relationship between the selection factors and purchase intention will be analyzed with perceived value as a mediator. Design/methodology - This work aims to empirically analyze the purchase intention of private label fresh food using statistical analysis. In this study, a hypothetical causal model consisting of 6 latent variables and 24 measured variables is developed based on the literature review. To validate the research hypotheses and the research model, SPSS23.0/AMOS23.0 is used to analyze factors such as validity and reliability, as well as structural equation modeling. Findings - The hypothetical model established in this study is of general applicability. In respect to PLFF, perceived value, while significantly influencing purchase intention in combination with four selection factors (perceived quality, perceived price, brand trust, and store image), mediates partially between the first three factors and purchase intention, which rules out the impact and mediating effect of store image on purchase intention. Originality/value - These research results, as helpful insights into the present circumstances of Chinese PLFF in the domestic market, provide useful information and guidance for Korean retailers and service providers to innovate production and service, as well as develop marketing and promotion strategies, so that they can shift private label goods with advantages from domestic demand to export, thus increasing overseas profitability. Further, this work will also contribute to relevant research.

중국 제조업 상장기업의 가치평가 설명요인에 관한 연구 (What explains firm valuation? Evidence from the Chinese manufacturing sector)

  • ;안연주;최문섭
    • 무역학회지
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    • 제45권2호
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    • pp.229-262
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    • 2020
  • The price-to-earnings ratio (PER) is an important indicator to measure the stock price and profitability of a firm; it is also the most used valuation indicator among investors. When using the PER to compare the investment values of different stocks, these stocks must come from the same sector. This study mainly focuses on the China's listed manufacturing firms. By learning from previous research results and analyzing the current situation, we studied the correlation between the manufacturing sector's PER and its influencing factors from both macro and micro perspectives, the combination of which eventually sheds light on such correlation. Analyzing GDP growth rate data, Manufacturing Purchasing Managers' Index, and other macroeconomic variables from 2008 to 2018, we conclude that these variables jointly have a certain impact on the average PER of the manufacturing sector. We then form panel data based on relevant (2014-2018) data gathered from 317 of China's A-listed manufacturing firms to study the impact of micro-variables on PER. By using Stata and other software to analyze the panel data, we reach the conclusion that the Debt to Asset Ratio, Return on Equity, EPS growth rate, Operating Profit Ratio, Dividend Payout Ratio, and firm size have a significant impact on PER. The Current Ratio, Treasury Stock ratio and Ownership Concentration have no distinct effect on PER. Based on our empirical findings, we design a theoretical model that affects the PER.

Long-term supplementation with a combination of beta-hydroxy-beta-methylbutyrate, arginine, and glutamine for pressure ulcer in sedentary older adults: a retrospective matched case-control study

  • Igor Kisil;Yuri Gimelfarb
    • Journal of Yeungnam Medical Science
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    • 제40권4호
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    • pp.364-372
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    • 2023
  • Background: Growing evidence suggests that beta-hydroxy-beta-methylbutyrate (HMB), arginine (Arg), and glutamine (Gln) positively affect wound recovery. This study investigated the effects of long-term administration of HMB/Arg/Gln on pressure ulcer (PU) healing in sedentary older adults admitted to geriatric and rehabilitation care facilities. Methods: This was a pilot retrospective case (standard of care and HMB/Arg/Gln)-control (standard of care alone) clinical study. Outcome measures were relative healing rates and Pressure Ulcer Scale for Healing (PUSH) scores (calculated after 4, 8, 12, 16, and 20 weeks) and time to healing. Results: The study subpopulation was comprised of 14 participants (four males, 28.6%) with the median age of 85.5 years (interquartile range [IQR], 82.0-90.2 years). The control subpopulation was comprised of 31 participants (18 males, 58.1%) with the median age of 84.0 years (IQR, 78.0-90.0 years). At the beginning of follow-up, there were no statistically significant demographic (sex and age) and clinical (main diagnosis, baseline area, and PU perimeter) differences between the groups. During the study period, there were no significant differences in the relative healing rates and PUSH scores between the subpopulations. The median time to complete healing in the study and control populations was 170.0 days (95% confidence interval [CI], 85.7-254.3) and 218.0 days (95% CI, 149.2- 286.7) (log-rank, chi-square=3.99; p<0.046), respectively. Conclusion: More than 20 weeks of HMB/Arg/Gln supplementation had a positive effect on difficult PU healing in older adults with multiple comorbidities.

Comparative Efficacy and Safety of Radiofrequency Ablation and Microwave Ablation in the Treatment of Benign Thyroid Nodules: A Systematic Review and Meta-Analysis

  • Hendra Zufry;Timotius Ivan Hariyanto
    • Korean Journal of Radiology
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    • 제25권3호
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    • pp.301-313
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    • 2024
  • Objective: The current body of evidence lacks clarity regarding the comparative efficacy and safety of radiofrequency ablation (RFA) and microwave ablation (MWA) as minimally invasive treatments for benign thyroid nodules. The primary objective of this study is to clarify these concerns. Materials and Methods: A comprehensive search was conducted using the Cochrane Library, Scopus, Europe PMC, and Medline databases until October 10th, 2023, using a combination of relevant keywords. This study incorporated literature that compared RFA and MWA for benign thyroid nodules. The primary outcome was the volume reduction ratio (VRR) from baseline to follow-up. Secondary outcomes were symptom score, cosmetic score, ablation time, major complications rate, hemorrhage, hoarseness, skin burn, cough, and sympathetic nerve injury. We used Risk of Bias in Non-randomized Studies - of Interventions (ROBINS-I) tool to assess the risk of bias in the included studies. We employed random effects models to analyze the standardized mean difference (SMD) and odds ratio for the presentation of outcomes. Results: Nine studies with 2707 nodules were included. The results of our meta-analysis indicated similar efficacy between RFA and MWA in terms of VRR during the 1 (SMD 0.06; 95% confidence interval [CI]: -0.13 to 0.26; P = 0.52) and 3 (SMD 0.11; 95% CI: -0.03 to 0.25; P = 0.12) months of follow-up. VRR was significantly higher in RFA than in MWA at the 6 (SMD 0.25; 95% CI: 0.06-0.43; P = 0.008) and 12 month of follow-up (SMD 0.38; 95% CI: 0.17 to 0.59; P < 0.001). There were no significant differences between RFA and MWA in symptom scores, cosmetic scores, or the incidence of complications, including hemorrhage, hoarseness, skin burn, cough, and sympathetic nerve injury. Conclusion: RFA showed a higher VRR than MWA at 6 and 12-month follow-ups, with a comparable safety profile.

Efficacy of Acupuncture for Parkinson's Disease over the Last Decade: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

  • Yeonju Kim;Yigun Lim;Subin Ahn;Junyeop Oh;Yoonbyeong Chae;Yoomin Choi;Jong Uk Kim
    • Journal of Acupuncture Research
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    • 제41권1호
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    • pp.29-52
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    • 2024
  • The aim of this review is to consolidate findings from clinical investigations spanning the past decade regarding the impact of acupuncture on Parkinson's disease (PD). The objective is to assess the efficacy of acupuncture as a therapeutic approach to PD, with the intention of informing future clinical practices and advancing the foundation for subsequent research endeavors in this area. A comprehensive literature search was conducted to identify clinical trials exploring the effects of acupuncture on PD between January 2014 and August 2023. Databases search included PubMed, EMBASE, CNKI, OASIS, KISS, KMBASE, RISS, and ScienceON. Quantitative evidence from randomized controlled trials (RCTs) was systematically reviewed, and the methodological quality of the included studies was assessed using Cochrane's risk of bias tool. Meta-analysis was performed using Review Manager (RevMan) 5.4.1 software. The systematic review encompassed a total of 38 RCTs involving 2,786 participants. Meta-analysis of 12 studies revealed that individuals treated with a combination of acupuncture and Western medicine exhibited notable improvements compared to those receiving Western medicine alone or sham acupuncture alongside Western medicine. However, the overall quality of the RCTs was deemed low, and no serious adverse events were reported. Across clinical investigations conducted in the past decade, acupuncture appears to hold promise as a complementary treatment for PD patients when administered alongside Western medicine. Nevertheless, this study identifies certain limitations that warrant consideration in future research endeavors. Enhanced emphasis on conducting high-quality RCTs is imperative to comprehensively evaluate the efficacy of acupuncture in managing PD.

Validation of Reference Genes for Quantitative Real-Time PCR in Bovine PBMCs Transformed and Non-transformed by Theileria annulata

  • Zhao, Hongxi;Liu, Junlong;Li, Youquan;Yang, Congshan;Zhao, Shuaiyang;Liu, Juan;Liu, Aihong;Liu, Guangyuan;Yin, Hong;Guan, Guiquan;Luo, Jianxun
    • Parasites, Hosts and Diseases
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    • 제54권1호
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    • pp.39-46
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    • 2016
  • Theileria annulata is a tick-borne intracellular protozoan parasite that causes tropical theileriosis, a fatal bovine lymphoproliferative disease. The parasite predominantly invades bovine B lymphocytes and macrophages and induces host cell transformation by a mechanism that is not fully comprehended. Analysis of signaling pathways by quantitative real-time PCR (qPCR) could be a highly efficient means to understand this transformation mechanism. However, accurate analysis of qPCR data relies on selection of appropriate reference genes for normalization, yet few papers on T. annulata contain evidence of reference gene validation. We therefore used the geNorm and NormFinder programs to evaluate the stability of 5 candidate reference genes; 18S rRNA, glyceraldehyde-3-phosphate dehydrogenase (GAPDH), ACTB (${\beta}-actin$), PRKG1 (protein kinase cGMP-dependent, type I) and TATA box binding protein (TBP). The results showed that 18S rRNA was the reference gene most stably expressed in bovine PBMCs transformed and non-transformed with T. annulata, followed by GAPDH and TBP. While 18S rRNA and GAPDH were the best combination, these 2 genes were chosen as references to study signaling pathways involved in the transformation mechanism of T. annulata.

무릎 골관절증을 보이는 개에서 자가지방유래 중배엽성 줄기세포 치료 다섯 증례 (Clinical Application of Autologous Adipose Tissue Derived Mesenchymal Stem Cells in Five Dogs with Stifle Joint Osteoarthrosis)

  • 윤헌영;강동준;이수한;정순욱;정병현
    • 한국임상수의학회지
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    • 제31권3호
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    • pp.253-257
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    • 2014
  • 후지 파행 증상을 보이는 다섯 마리 개가 내원하였다. 무릎 관절 신체 검사에서 통증, 파행, 슬개골 탈구, 또는 인대 손상을 확인 하였다. 일반 방사선 사진에서 골증식체와 연골하 병변을 확인 하였고 골관절증 점수가 높은 것을 확인하였다. 수술적 교정과 자가지방 유래 줄기세포 치료의 혼합 방법 또는 자가지방 유래 줄기세포의 경피 주입단독 방법을 보호자의 동의 하에 실시 하였다. $1{\times}10^6$ 개의 줄기세포를 PBS와 함께 주입 하였다. 수술 후 확인은 수의사의 신체검사를 통해 12개월까지 실시 하였다. 주입 후 6개월 또는 12 개월에 파행, 통증, 골관절증 점수가 개선되었음을 확인 하였고 일반 방사선 사진에서도 골증식체와 연골하 병변이 줄어든 것을 확인 할 수 있었다. 본 증례들를 통해 자가지방 유래 줄기 세포 치료가 골관절증을 보이는 개에서 효과적인 방법임을 확인 할 수 있었다.

Isolation of a Quinone-rich Fraction from Ardisia crispa Roots and its Attenuating Effects on Murine Skin Tumorigenesis

  • Yeong, Looi Ting;Hamid, Roslida Abdul;Yazan, Latifah Saiful;Khaza'ai, Huzwah
    • Asian Pacific Journal of Cancer Prevention
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    • 제14권4호
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    • pp.2301-2305
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    • 2013
  • Ardisia crispa (Family: Myrsinaceae) is an evergreen, fruiting shrub that has been traditionally used as folklore medicine. Despite a scarcity of research publications, we have succeeded in showing suppressive effects on murine skin papillomagenesis. In extension, the present research was aimed at determining the effect of a quinone-rich fraction (QRF) isolated from the same root hexane extract on both initiation and promotion stages of carcinogenesis, at the selected dose of 30 mg/kg. Mice (groups I-IV) were initiated with a single dose of 7,12-dimethylbenz(${\alpha}$)anthracene (DMBA, $100{\mu}g/100{\mu}l$) followed by repeated promotion of croton oil (1%) twice weekly for 20 weeks. In addition, group I (anti-initiation) received QRF 7 days before and after DMBA; group II (anti-promotion) received QRF 30 minutes before each croton oil application; group III (anti-initiation/promotion) was treated with QRF as a combination of group I and II. A further two groups served as vehicle control (group V) and treated control (group VI). As carcinogen control, group IV showed the highest tumor volume ($8.79{\pm}5.44$) and tumor burden ($3.60{\pm}1.17$). Comparatively, group III revealed only 20% of tumor incidence, tumor burden ($3.00{\pm}1.00$) and tumor volume ($2.40{\pm}1.12$), which were significantly different from group IV. Group II also showed significant reduction of tumor volume (3.11), tumor burden (3.00) and tumor incidence (11.11%), along with prominent increase of latency period of tumor formation (week 12). Group I, nonetheless, demonstrated marked increment of tumor incidence by 40% with prompted latency period of tumor formation (week 7). No tumor formation was observed in groups V and VI. This study provided clear evidence of inhibitory effects of QRF during promotion period which was in agreement with our previous findings. The mechanism(s) underlying such effects have yet to be elucidated.

무선인지 애드 혹 네트워크를 위한 순차적 협력 스펙트럼 센싱 기법 (An contention-aware ordered sequential collaborative spectrum sensing scheme for CRAHN)

  • 웬타난;구인수
    • 인터넷정보학회논문지
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    • 제12권4호
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    • pp.35-43
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    • 2011
  • 최근 들어 무선인지 애드 혹 네트워크(CRAHN)는 임시적으로 활용되지 않은 라이선스 스펙트럼을 기회주의적 방법으로 사용하여 통신하는 차세대 애드 혹 네트워크로 각광받고 있다. 여타 무선인지 시스템에서와 같이, 정확한 스펙트럼 센싱은 무선인지 애드 혹 네트워크 구현을 위한 필수 요소 기술이다. 중앙 제어국 중심의 협력 스펙트럼 센싱 기법은 센싱 성능을 향상 시킬 수 있으나, 무선인지 애드 혹 네트워크와 같은 비인프라망에서는 중앙 제어국이 없어 협력 센싱 구현이 어렵다. 본 논문에서는 무선인지 애드 혹 네트워크를 위한 새로운 순차적 협력 스펙트럼 센싱 기법을 제안한다. 제안된 기법에서는 Dempster Shafer 이론 기반으로 국부 스펙트럼 센싱 데이터의 신뢰도가 가장 높은 인지 노드가 임시 중앙국이 되어 주변 센서 노드로부터 스펙트럼 센싱값을 수집하여 스펙트럼 사용 유무에 대한 최종 결정을 만들고 그 최종 결정을 이웃 노드들에게 전송한다. 또한 본 논문에서는 분산 방법으로 개별 인지 노드들이 자신의 센싱 데이터를 효율적으로 교환하기 위한, 센싱데이터 신뢰도 순서 기반의 전송 메커니즘을 제안하였다. 시뮬레이션을 통해 제안된 방식은 기존 중앙 제어국 중심의 협력 스펙트럼 센싱 기법과 유사한 스펙트럼 센싱 성능을 제공하는 동시에, 최종 스펙트럼 결정까지 소요되는 센싱 데이터 수집시간 및 교환되는 센싱 데이터 량을 현저히 줄일 수 있음을 보였다.

고양이에서 방광요막관 게실의 외과적 치료 증례 (Surgical Correction of a Vesicourachal Diverticulum in a Cat)

  • 윤헌영;노미영;정순욱
    • 한국임상수의학회지
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    • 제29권6호
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    • pp.509-512
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    • 2012
  • 암컷, 4년령, 6.5 kg의 단모종 고양이가 배뇨실금 및 배뇨곤란 증상을 주증으로 내원하였다. 신체 검사에서 방광 팽창을 동반한 배뇨곤란 증상을 확인 하였고, 방사선 검사와 초음파 검사에서 2개의 작은 방광 결석과 방광내 슬러지를 각각 확인 하였다. 소변 검사에서 혈뇨와 세균뇨를 확인 하였다. 식염수를 이용한 방광 세척과 항생제 치료를 4주간 실시 하였으나 치료 효과가 미미하였다. 선천적 이상을 확인하기 위해 배설성 요로조영술을 실시하였고, 작은 게실이 방광 앞쪽 끝에서 관찰 되었다. 방광요막관 게실이 의심 되어 탐색적 개복술을 실시 하였고 삼각형 모양의 게실이 방광 앞쪽 끝에서 확인 되었다. 방광 결석 제거를 위해 방광 절개술이 실시 되었고 게실 절제를 위해 방광 부분 절제술이 실시 되었다. 방광 앞쪽 끝 부분을 지름 약 2 cm 정도 절제 하였다. 수술 후 5일 째 정상 배뇨가 가능하였다. 수술 후 정기 검진은 신체 검사를 통해 2년 동안 실시 되었으며 배뇨 곤란과 배뇨 실금 증상이 관찰 되지 않았다.