• Title/Summary/Keyword: Event duration

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Role and Clinical Importance of Progressive Changes in Echocardiographic Parameters in Predicting Outcomes in Patients With Hypertrophic Cardiomyopathy

  • Kyehwan Kim;Seung Do Lee;Hyo Jin Lee;Hangyul Kim;Hye Ree Kim;Yun Ho Cho;Jeong Yoon Jang;Min Gyu Kang;Jin-Sin Koh;Seok-Jae Hwang;Jin-Yong Hwang;Jeong Rang Park
    • Journal of Cardiovascular Imaging
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    • v.31 no.2
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    • pp.85-95
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    • 2023
  • BACKGROUND: The prognostic utility of follow-up transthoracic echocardiography (FU-TTE) in patients with hypertrophic cardiomyopathy (HCM) is unclear, specifically in terms of whether changes in echocardiographic parameters in routine FU-TTE parameters are associated with cardiovascular outcomes. METHODS: From 2010 to 2017, 162 patients with HCM were retrospectively enrolled in this study. Using echocardiography, HCM was diagnosed based on morphological criteria. Patients with other diseases that cause cardiac hypertrophy were excluded. TTE parameters at baseline and FU were analyzed. FU-TTE was designated as the last recorded value in patients who did not develop any cardiovascular event or the latest exam before event development. Clinical outcomes were acute heart failure, cardiac death, arrhythmia, ischemic stroke, and cardiogenic syncope. RESULTS: Median interval between the baseline TTE and FU-TTE was 3.3 years. Median clinical FU duration was 4.7 years. Septal trans-mitral velocity/mitral annular tissue Doppler velocity (E/e'), tricuspid regurgitation velocity, left ventricular ejection fraction (LVEF), and left atrial volume index (LAVI) at baseline were recorded. LVEF, LAVI, and E/e' values were associated with poor outcomes. However, no delta values predicted HCM-related cardiovascular outcomes. Logistic regression models incorporating changes in TTE parameters had no significant findings. Baseline LAVI was the best predictor of a poor prognosis. In survival analysis, an already enlarged or increased size LAVI was associated with poorer clinical outcomes. CONCLUSIONS: Changes in echocardiographic parameters extracted from TTE did not assist in predicting clinical outcomes. Cross-sectionally evaluated TTE parameters were superior to changes in TTE parameters between baseline and FU at predicting cardiovascular events.

Comparison of endoscopic ultrasound-guided drainage and percutaneous catheter drainage of postoperative fluid collection after pancreaticoduodenectomy

  • Da Hee Woo;Jae Hoon Lee;Ye Jong Park;Woo Hyung Lee;Ki Byung Song;Dae Wook Hwang;Song Cheol Kim
    • Annals of Hepato-Biliary-Pancreatic Surgery
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    • v.26 no.4
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    • pp.355-362
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    • 2022
  • Backgrounds/Aims: Postoperative fluid collection is a common complication of pancreatic resection without clear management guidelines. This study aimed to compare outcomes of endoscopic ultrasound (EUS)-guided trans-gastric drainage and percutaneous catheter drainage (PCD) in patients who experienced this adverse event after pancreaticoduodenectomy (PD). Methods: Demographic and clinical data and intervention outcomes of 53 patients who underwent drainage procedure (EUS-guided, n = 32; PCD, n = 21) for fluid collection after PD between January 2015 and June 2019 in our tertiary referral center were retrospectively analyzed. Results: Prior to drainage, 83.0% had leukocytosis and 92.5% presented with one or more of the following signs or symptoms: fever (69.8%), abdominal pain (69.8%), and nausea/vomiting (17.0%). Within 8 weeks of drainage, 77.4% showed a diameter decrease of more than 50% (87.5% in EUS vs. 66.7% in PCD, p = 0.09). Post-procedural intravenous antibiotics were used for an average of 8.1 ± 4.3 days and 12.4 ± 7.4 days for EUS group and PCD group, respectively (p = 0.01). The EUS group had a shorter post-procedural hospital stay than the PCD group (9.8 ± 1.1 vs. 15.8 ± 2.2 days, p < 0.01). However, the two groups showed no statistically significant difference in technical or clinical success rate, reintervention rate, or adverse event rate. Conclusions: EUS-guided drainage and PCD are both safe and effective methods for managing fluid collection after PD. However, EUS-guided drainage can shorten hospital stay and duration of intravenous antibiotics use.

Estimation of Runoff Characteristics of Non-point Pollutant Source by Land Cover Characteristics (토지피복 특성에 따른 비점오염원 유출특성 평가)

  • Lee, Jae-Woon;Yi, Youn-Jeong;Kwon, Hun-Gak;Yoon, Jong-Su;Lee, Chun-Sik;Cheon, Se-Uk
    • Journal of Environmental Science International
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    • v.21 no.8
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    • pp.977-988
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    • 2012
  • This study analyzed the characteristics of stormwater runoff by rainfall type in orchard areas and transportation areas for 2 years(2010~2011year). Effluents were monitored to calculate the Event Mean Concentrations(EMCs) and runoff loads of each pollutant. The pollutant EMCs by volume of stormwater runoff showed the ranges of BOD 0.9~13.6 mg/L, COD 13.7~45.2 mg/L, SS 4.1~236.4 mg/L, T-N 2.123~21.111 mg/L, T-P 0.495~2.214 mg/L in the orchard areas, and was calculated as BOD 2.3~22.5mg/L, COD 4.4~91.1 mg/L, SS 4.3~138.3 mg/L, T-N 0.700~13.500 mg/L, T-P 0.082~1.345 mg/L in the transportation areas. The correlation coefficient of determination in the orchard area was investigated in the order of Total Rainfall(0.81) > Total Runoff(0.76) > Rainfall Intensity(0.56) > Rainfall Duration(0.46) > Antecedent Dry Days(0.27). Also, in the case of the transportation area was investigated in the order of Total Rainfall (0.55) > Total Runoff(0.54) > Rainfall Intensity(0.53) > Rainfall Duration(0.24) > Antecedent Dry Days(0.14). As the result, comparing valuables relating to runoff of non-pollutant source between orchard areas and transportation areas, orchard area($R^2{\geq}0.5$ : X3, X4, X5) was investigated to have more influence of diverse independent valuables compared to the transportation area($R^2{\geq}0.5$ : X3, X4) and the difference of discharge influence factor by the land characteristics appeared apparently.

Drought Risk Analysis in Seoul Using Cheugugi and Climate Change Scenario Based Rainfall Data (측우기 및 미래 기후변화 시나리오 자료를 활용한 서울지역의 가뭄 위험도 분석)

  • Kim, Ji Eun;Yu, Ji Soo;Lee, Joo-Heon;Kim, Tae-Woong
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.38 no.3
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    • pp.387-393
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    • 2018
  • Considering the effect of climate change, a quantitative analysis of extreme drought is needed to reduce the damage from extreme droughts. Therefore, in this study, a quantitative risk analysis of extreme drought was conducted. The threshold level method was applied to define a drought event using Cheugugi rainfall data in past, gauged rainfall data in present, and climate change scenario rainfall data in future. A bivariate drought frequency analysis was performed using the copula function to simultaneously consider two major drought characteristics such as duration and severity. Based on the bivariate drought frequency curves, the risks for the past, present and future were calculated and the risks for future extreme drought were analyzed comparing with the past and present. As a result, the mean drought duration of the future was shorter than that of past and present, however, the mean drought severity was much larger. Therefore short term and severe droughts were expected to occur in the future. In addition, the analysis of the maximum drought risk indicated that the future maximum drought risk was 1.39~1.94 times and 1.33~1.81 times higher than the past and present. Finally, the risk of extreme drought over past and present maximum drought in the future was very high, ranging from 0.989 to 1.0, and the occurrence probability of extreme drought was high in the future.

Characteristics of Pollutant Washed-off from Highways with Storm Runoff Duration (아스팔트 포장 고속도로의 강우 지속시간별 오염물질 유출 경향)

  • Kim Lee-Hyun;Lee Eun-Ju;Ko Seok-Oh;Kang Hee-Man
    • International Journal of Highway Engineering
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    • v.8 no.1 s.27
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    • pp.99-106
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    • 2006
  • During the dry periods, many types of pollutant are accumulating on the paved surface by vehicle activities. Particularly, the highways are stormwater intensive landuses because of high imperviousness and high pollutant mass emissions from vehicles. The accumulated pollutants in highways are washed-off during a rainfall event and are highly contributing on water quality of receiving water bodies. The stormwater runoff from the highways are containing various pollutants such as metals, oil & grease and toxic chemicals originated from vehicles. Therefore, this research is performed to find pollutant characteristics in the magnitude of statistical pollutant concentrations during storm periods. During the monitoring periods, the first-flush phenomenon is visibly occurred on most storm events, which is confirmed from hydro- and pollute-graphs. The 95% confidence intervals of washed-off pollutant concentration are ranged to 154.7-257.1 mg/L for 755,138.9-197.6 mg/L for COD, 3.5-6.4 mg/L for oil & grease, 6.3-9.2 mg/L for TN and 2.3-3.31 mg/L for TP. The first flush effect is mostly occurred within initial 30 min of storm duration.

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Response Time Analysis of Web Service Systems with Mixedly Distributed Stochastic Timed Net (혼합 분포 확률 시간 넷을 이용한 웹 서비스 시스템의 응답 시간 분석)

  • Yim, Jae-Geol;Do, Jae-Su;Shim, Kyu-Bark
    • Journal of Korea Multimedia Society
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    • v.9 no.11
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    • pp.1503-1514
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    • 2006
  • Today, consumers can access Internet from everywhere, therefore most commercial and other organizations provide their services on the Web. As the result, countless Web service systems are already on the Internet and more systems are under construction. Therefore, many researches of verifying that the system to be constructed will not have any deadlock and will run successfully without any problem at the early stage of design have been performed. Several Petri net based verification methods have also been published. However, they have focused on building Petri net models of Web service systems and none of them introduces efficient analysis methods. As a mathematical technique with which we can find the minimum duration time needed to fire all the transitions at least once and coming back to the initial marking in a timed net, the minimum cycle time method has been widely used in computer system analysis. A timed net is a modified version of a Petri net where a transition is associated with a delay time. A delay time used in a timed net is a constant even though the duration time associated with an event in the real world is a stochastic number in general. Therefore, this paper proposes 'Mixedly Distributed Stochastic Timed Net' where a transition can be associated with a stochastic number and introduce a minimum cycle time analysis method for 'Mixedly Distributed Stochastic Timed Net'. We also introduce a method of analysing a Web service system's response time with the minimum cycle time analysis method for 'Mixedly Distributed Stochastic Timed Net.'.

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A Clinical Trial to Assess the Efficacy of Acupuncture on Hot Flashes in Postmenopausal Women;Focusing on the comparison of the effects of Traditional Korean medical acupuncture (TKMA) and Minimal Acupuncture (MA)

  • Kim, Dong-Il;Roh, Jin-Ju;Choi, Min-Sun;Lee, Seung-Deok;Roh, Ju-Won;Yoon, Sang-Ho;Ahn, Hong-Yup;Oh, Dal-Seok;Choi, Sun-Mi
    • The Journal of Korean Medicine
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    • v.28 no.4
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    • pp.74-85
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    • 2007
  • Objective : In this study we wanted to confirm if proper stimulation and de-Qi of traditional Korean medical acupuncture could increase hot flash relief efficacy. Design : A randomized controlled, single blind study. We used two modalities of acupuncture, one with optimal stimulation [Study group; Korean medical acupuncture (TKMA)] and one with minimal stimulation [Control group; Minimal acupuncture (MA)]. Same acupoints [PC6(內關), HT8(少府), HT7(神門), LI4(合谷), ST36(足三里), SP6(三陰交), Ren4(關元)] were used in both groups. Fifty-two patients were treated twice a week for 8 weeks, and follow up was done after 4 weeks from the last treatment. Patients were checked hot flash VAS (visual analog scale), frequency and duration every time they visited. Results : Hot flash relief efficacy by 100mm hot flash VAS was obvious in both groups. Hot flash VAS scores of study group were smaller than the scores of control group at the early stage (3rd, $4^{th}$ and $8^{th}$ visit), but there wasn't a remarkable difference between study and control group at the end of the trial. Besides, diminution of hot flash VAS was faster and more even in the study group than control group by visualization using 'Box plot'. We compared frequency and duration of hot flash, 100mm sweating, palpitation, sleep disturbance VAS, and Kupperman Index, MENQOL, Patient's global assessment score. Both groups showed definite decrease from the baseline, but the difference was not statistically significant. There wasn't any adverse event. Hot flash relief efficacy was kept in most patients after 4 weeks' follow-up. Conclusion : Acupoint combination by Traditional Korean medical theory is effective on hot flashes and hot flash relief efficacy was faster and more even in optimal stimulation than minimal stimulation.

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Study on Design Capacity of Stormwater Pipe and Pumping Station considering Peak Rainfall Intensity (첨두강우강도를 고려한 우수관로 및 빗물펌프장의 설계용량 검토)

  • Chung, Gunhui;Sim, Kyu Bum;Kim, Eung Seok
    • Journal of Korea Water Resources Association
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    • v.47 no.9
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    • pp.777-787
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    • 2014
  • Stormwater pipe systems are most commonly used to discharge rainwater from the urban catchment covered by the impervious area. To design stormwater pipe and rainwater pumping station, frequency analysis is implemented using historical rainfall and the design rainfall is timely distributed using theoretical shape such as Huff distribution. This method cannot consider the rainfall intensity variation caused by climate change which is type of uncertainty. Therefore, in this study, runoff from Gasan1 stormwater pumping stations catchment is calculated using design rainfall distributed by the 2nd quartile distribution method and the historical rainfall events. From the analysis, the nodal flooding in the urban catchment is likely caused by the high peak rainfall event rather than the large amount of rainfall. The linear regression analysis is implemented. As a result, when several storms have the same amount of rainfall, the nodal flooding in the stormwater pipe systems could be caused by the high peak of storm events. Since as the storm duration become short, the peak rainfall become high, the nodal flooding likely become severe with the short storm duration. The uncertainty in the peak data of design rainfall is analyzed and this uncertainty has to be consider in the stormwater pipe design process.

ATPDraw Simulation for Transient Phenomena Analysis of Electrical Shock Underwater (수중 전격 과도현상 해석을 위한 ATPDraw 시뮬레이션)

  • Jung, Jong-Wook;Jung, Jin-Soo
    • Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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    • v.21 no.6
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    • pp.48-54
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    • 2007
  • This paper describes the analysis of transient phenomena on the point that a human body suffers an electrical shock. A couple of case studies were discussed by using an ATPDraw simulation tool. Two models for the case studies were constructed on the assumption that the electrical shock event takes place under water to simulate the severest condition ; the first model that the human body contacts with an energized part exposed to water ; the second model that both hands and feet simultaneously contact with the ground under water. After modeling, the transient phenomena for the models were analyzed by comparing the voltages and currents calculated at each part of the human body. As a result steep front kicks in voltage and current were observed as transient phenomena on the point that the human body contacts with the energized part exposed to water in the first model and the magnitudes of the kicks considerably increased. It was considered however, the effect of the kicks due to the commercial power source on the human body could be neglected because the product of the current through the body and the short duration is less than the safety limit. When both hands and feet simultaneously contact with the ground in the second model, the voltage generally decreased all over the body parts, while the current flowing through the chest abruptly increased. The duration of this current was very shot, as well, thus its effect on the electrical shock is considered insignificant. After all, it was confirmed through the simulation results that the electrical shock depends on the magnitude in voltage and the body impedance.

Drought assessment by bivariate frequency analysis using standardized precipitation index and precipitation deficit: focused on Han river basin (표준강수지수와 강수 부족량을 이용한 이변량 가뭄빈도해석: 한강유역을 중심으로)

  • Kwon, Minsung;Sung, Jang Hyun;Kim, Tae-Woong;Ahn, Jaehyun
    • Journal of Korea Water Resources Association
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    • v.51 no.10
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    • pp.875-886
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    • 2018
  • This study evaluated drought severity by bivariate frequency analysis using drought magnitude and precipitation deficit. A drought event was defined by Standardized Precipitation Index (SPI) and the precipitation deficit was estimated using reference precipitation corresponding to the SPI -1. In previous studies, drought magnitude and duration were used for bivariate frequency analysis. However, since these two variables have a largely linear relationship, extensibility of drought information is not great compared to the univariate frequency analysis for each variable. In the case of drought in 2015, return periods of 'drought magnitude-precipitation deficit' in the Seoul, Yangpyeong, and Chungju indicated severe drought over 300 years. However, the result of 'drought magnitude-duration' showed a significant difference by evaluating the return period of about 10, 50, and 50 years. Although a drought including the rainy season was seriously lacking in precipitation, drought magnitude did not adequately represent the severity of the absolute lack of precipitation. This showed that there is a limit to expressing the actual severity of drought. The results of frequency analysis for 'drought magnitude-precipitation deficit' include the absolute deficit of precipitation information, so which could consider being a useful indicator to cope with drought.