• Title/Summary/Keyword: Event Clustering

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Analysis of the Molecular Event of ICAM-1 Interaction with LFA-1 During Leukocyte Adhesion Using a Reconstituted Mammalian Cell Expression Model

  • Han, Weon-Cheol;Kim, Kwon-Seop;Park, Jae-Seung;Hwang, Sung-Yeoun;Moon, Hyung-Bae;Chung, Hun-Taeg;Jun, Chang-Duk
    • Animal cells and systems
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    • v.5 no.3
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    • pp.253-262
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    • 2001
  • Ligand-receptor clustering event is the most important step in leukocyte adhesion and spreading on endothelial cells. Intercellular adhesion molecule-1 (ICAM-1) has been shown to enhance leukocyte adhesion, but the molecular event during the process of adhesion is unclear. To visualize the dynamics of ICAM-1 movement during adhesion, we have engineered stable Chinese hamster ovary cell lines expressing ICAM-1 fused to a green fluorescent protein (IC1_GFP/CHO) and examined them under the fluorescence microscopy. The transfection of IC1_GFP alone in these cells was sufficient to support the adhesion of K562 cells that express $\alpha$L$\beta$2 (LFA-1) integrin stimulated by CBR LFA-1/2 mAb. This phenomenon was mediated by ICAM-1-LFA-1 interactions, as an mAb that specifically inhibits ICAM-1-LFA-1 interaction (RRl/l) completely abolished the adhesion of LFA-1* cells to IC1_ GFP/CHO cells. We found that the characteristic of adhesion was followed almost immediately (~10 min) by the rapid accumulation of ICAM-1 on CHO cells at a tight interface between the two cells. Interestingly, ICI_GFP/CHO cells projected plasma membrane and encircled approximately half surface of LFA-1+ cells, as defined by confocal microscopy. This unusual phenomenon was also confirmed on HUVEC after adhesion of LFA-1* cells. Neither cytochalasin D nor 2,3-butanedione 2-monoxime an inhibitor of myosin light chain kinase blocked LFA-1-mediated ICAM-1 clustering, indicating that actin cytoskeleton and myosin-dependent contractility are not necessary for ICAM-1 clustering. Taken together, we suggest that leukocyte adhesion to endothelial cells induces specialized form of ICAM-1 clustering that is distinct from immunological synapse mediated by T cell interaction with antigen presenting cells.

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A Study of Basic Design Method for High Availability Clustering Framework under Distributed Computing Environment (분산컴퓨팅 환경에서의 고가용성 클러스터링 프레임워크 기본설계 연구)

  • Kim, Jeom Goo;Noh, SiChoon
    • Convergence Security Journal
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    • v.13 no.3
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    • pp.17-23
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    • 2013
  • Clustering is required to configure clustering interdependent structural technology. Clustering handles variable workloads or impede continuity of service to continue operating in the event of a failure. Long as high-availability clustering feature focuses on server operating systems. Active-standby state of two systems when the active server fails, all services are running on the standby server, it takes the service. This function switching or switchover is called failover. Long as high-availability clustering feature focuses on server operating systems. The cluster node that is running on multiple systems and services have to duplicate each other so you can keep track of. In the event of a node failure within a few seconds the second node, the node shall perform the duties broken. Structure for high-availability clustering efficiency should be measured. System performance of infrastructure systems performance, latency, response time, CPU load factor(CPU utilization), CPU processes on the system (system process) channels are represented.

Twitter Hashtags Clustering with Word Embedding (Word Embedding기반 Twitter 해시 태그 클러스터링)

  • Nguyen, Tien Anh;Yang, Hyung-Jeong
    • Proceedings of the Korea Contents Association Conference
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    • 2019.05a
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    • pp.179-180
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    • 2019
  • Nowadays, clustering algorithm is considered as a promising solution for lacking human-labeled and massive data of social media sites in numerous machine learning tasks. Many researchers propose disaster event detection systems have ability to determine special local events, such as missing people, public transport damage by clustering similar tweets and hashtags together. In this paper, we try to extend tweet hashtag feature definition by applying word embedding. The experimental results are described that word embedding achieve better performance than the reference method.

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Data-centric Energy-aware Re-clustering Scheme for Wireless Sensor Networks (무선 센서 네트워크를 위한 데이터 중심의 에너지 인식 재클러스터링 기법)

  • Choi, Dongmin;Lee, Jisub;Chung, Ilyong
    • Journal of Korea Multimedia Society
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    • v.17 no.5
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    • pp.590-600
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    • 2014
  • In the wireless sensor network environment, clustering scheme has a problem that a large amount of energy is unnecessarily consumed because of frequently occurred entire re-clustering process. Some of the studies were attempted to improve the network performance by getting rid of the entire network setup process. However, removing the setup process is not worthy. Because entire network setup relieves the burden of some sensor nodes. The primary aim of our scheme is to cut down the energy consumption through minimizing entire setup processes which occurred unnecessarily. Thus, we suggest a re-clustering scheme that considers event detection, transmitting energy, and the load on the nodes. According to the result of performance analysis, our scheme reduces energy consumption of nodes, prolongs the network lifetime, and shows higher data collection rate and higher data accuracy than the existing schemes.

Analysis Framework using Process Mining for Block Movement Process in Shipyards (조선 산업에서 프로세스 마이닝을 이용한 블록 이동 프로세스 분석 프레임워크 개발)

  • Lee, Dongha;Bae, Hyerim
    • Journal of Korean Institute of Industrial Engineers
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    • v.39 no.6
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    • pp.577-586
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    • 2013
  • In a shipyard, it is hard to predict block movement due to the uncertainty caused during the long period of shipbuilding operations. For this reason, block movement is rarely scheduled, while main operations such as assembly, outfitting and painting are scheduled properly. Nonetheless, the high operating costs of block movement compel task managers to attempt its management. To resolve this dilemma, this paper proposes a new block movement analysis framework consisting of the following operations: understanding the entire process, log clustering to obtain manageable processes, discovering the process model and detecting exceptional processes. The proposed framework applies fuzzy mining and trace clustering among the process mining technologies to find main process and define process models easily. We also propose additional methodologies including adjustment of the semantic expression level for process instances to obtain an interpretable process model, definition of each cluster's process model, detection of exceptional processes, and others. The effectiveness of the proposed framework was verified in a case study using real-world event logs generated from the Block Process Monitoring System (BPMS).

Information Relationship Representation using Event Abstraction (이벤트 추상화를 통한 정보관계 표현)

  • Lim, Keun
    • Journal of the Korea Society of Computer and Information
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    • v.7 no.4
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    • pp.1-7
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    • 2002
  • In this paper, it will be supplied to the representation of event abstraction which is useful for understanding information relationship of the object-oriented programs. And the clustering concept with the events will be applied to abstract the events. By clustering the events, user can set the information about the function of the classes and the retrieval of the class library.

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Improving Process Mining with Trace Clustering (자취 군집화를 통한 프로세스 마이닝의 성능 개선)

  • Song, Min-Seok;Gunther, C.W.;van der Aalst, W.M.P.;Jung, Jae-Yoon
    • Journal of Korean Institute of Industrial Engineers
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    • v.34 no.4
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    • pp.460-469
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    • 2008
  • Process mining aims at mining valuable information from process execution results (called "event logs"). Even though process mining techniques have proven to be a valuable tool, the mining results from real process logs are usually too complex to interpret. The main cause that leads to complex models is the diversity of process logs. To address this issue, this paper proposes a trace clustering approach that splits a process log into homogeneous subsets and applies existing process mining techniques to each subset. Based on log profiles from a process log, the approach uses existing clustering techniques to derive clusters. Our approach are implemented in ProM framework. To illustrate this, a real-life case study is also presented.

Analysis of Massive Scholarly Keywords using Inverted-Index based Bottom-up Clustering (역인덱스 기반 상향식 군집화 기법을 이용한 대규모 학술 핵심어 분석)

  • Oh, Heung-Seon;Jung, Yuchul
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.19 no.11
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    • pp.758-764
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    • 2018
  • Digital documents such as patents, scholarly papers and research reports have author keywords which summarize the topics of documents. Different documents are likely to describe the same topic if they share the same keywords. Document clustering aims at clustering documents to similar topics with an unsupervised learning method. However, it is difficult to apply to a large amount of documents event though the document clustering is utilized to in various data analysis due to computational complexity. In this case, we can cluster and connect massive documents using keywords efficiently. Existing bottom-up hierarchical clustering requires huge computation and time complexity for clustering a large number of keywords. This paper proposes an inverted index based bottom-up clustering for keywords and analyzes the results of clustering with massive keywords extracted from scholarly papers and research reports.

A Study on the efficiency of similarity and clustering measure in Historical Writing Document (역사적 기록 문서에서 효율적인 유사도 및 클러스터링 측정에 관한 연구)

  • 한광덕
    • Journal of the Korea Society of Computer and Information
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    • v.7 no.4
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    • pp.94-101
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    • 2002
  • It expected a lot of changes in mass media and documentation expression as documents on web are getting diverse, complex and massive. An Annals of The Chosun Dynasty is a very important document used for researching historical facts and is published as CD-Rom. However. The CD-Rom was composed as content-based and using simple search method, therefore it's very difficult to make determine event-relationship between documents factors. Because of that, we studied to discover event-relationship between documents through clustering and efficient similarity method among Annals of The Chosun Dynasty. For the research method, we discovered the best similarity method for historical written documents through simulation similarity measures of Annals of The Chosun Dynasty documents. Then we did simulation-clustering documents based on similarity probability. In evaluation of the clustered documents , the results were the same as when manually figured.

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The Polysemy of Da3: An ontology-based lexical semantic study

  • Hong, Jia-Fei;Huang, Chu-Ren;Ahrens, Kathleen
    • Proceedings of the Korean Society for Language and Information Conference
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    • 2007.11a
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    • pp.155-162
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    • 2007
  • In this study, we explore the polysemy of da3 through the ontological conceptual structure found in SUMO. First, we divide several different senses for da3, clustering physical event senses and metaphorical event senses. In here, we only focus on physical event senses of da3. From the physical event senses of da3, we divide them into two main categories: 1) hit and 2) pump. We then use SUMO ontological concepts to identify these physical senses. Finally, we can observe the common patterns of the "hit" sense group and the "pump" sense group for da3.

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