• Title/Summary/Keyword: Evaporation rate constant

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Preparation of biodegradable microspheres containing water-soluble drug, $\beta$-lactam$ antibiotic

  • Kim, Jin-Hee;Kwon, Ick-Chan;La, Sung-Bum;Jeong, Seo-Young;Young, Taek-Sohn;Seo, Young-Jeong
    • Archives of Pharmacal Research
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    • v.19 no.1
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    • pp.30-35
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    • 1996
  • Poly(l-lactic acid)(PLLA) microspheres loaded with ampicillin sodium (AMP-Na_, .betha.-lactam antibiotic, were prepared by a w/o/w multiple emulsion-solvent evaporation method. The amounts of each component in three phases (inner water phase, organic phase, and outer water phase) wre carefully examined in the preparation of PLLA microspheres. The stirring rate, another preparation parameter, was also investigated for study on the effect of mechanical stress on the drug loading and morphology of PLLA microspheres. Most of the preparation parameters had a great influence on the drug loading, surface morphology and size distribution of PLLA microspheres. PLLA microspheres with 15.89 w/w% drug loading were subjected to the in vitro release experimet. The release of ampicillin sodium was constant at a rate of 1.68 $mug/ml/day$ per 1 mg of microspheres for 18 days initial burst effect.

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A Study on the Combustion of Fish Oil as Alternative Fuels for Diesel Engines (디젤기관용대체연료로서의 어유연소에 관한 연구)

  • 서정주
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.32 no.2
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    • pp.148-156
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    • 1996
  • The combustion characteristics of diesel oil and fish oil blended with diesel oils were investigated at various blending rate of fish oil in diesel engine and constant volume combustion bomb. The evaporation and combustion duration of diesel oil and fish oil blended with diesel oils were respectively different high and low temperature. The dependence of ignition delay on the temperature was different in high and low temperature ranges which were divided at the 773K. The ignition delay become longer than that of diesel oil as the blending rate of fish oil increases, and its difference were larger at different loads. The densityof smoke was lower as the blending rate of fish oil increases, and the rate offuel consumption showed no significant difference between diesel oil and fish oil blended with diesel oils.

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A Study on the Diesel Spray Evaporation and Combustion Characteristics in Constant Volume Chamber (정적연소실내의 디젤분무증발과 연소특성에 관한 연구)

  • Kim, S.H.;Kim, S.J.;Lee, M.B.;Kim, E.S.
    • Transactions of the Korean Society of Automotive Engineers
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    • v.2 no.6
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    • pp.102-109
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    • 1994
  • As a fundamental study to apply high pressure injection system to direct injection diesel engine, fuel injection system and constant volume combustion chamber were made and the behaviors of evaporating spray with the variation of injection pressure and the ambient gas temperature were observed by using high speed camera, and the combusion characteristics with the variation of injection pressure and A/F ratio were analyzed. As injection pressure increases, spray tip penetration and spray angle increase and, as a results spray volume increases. This helps an uniform mixing of fuel and air. Spray liquid core length decreases as ambient gas temperature increases, while it decreases as injection pressure increases but the effect of ambient gas temperature is dorminant. As injection pressure increases, ignition delay is shortened and combustion rate being raised, maximum heat release rate increases. It become clear that High injection pressure has high level of potential to improve the performance of DI-diesel engine.

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Fabrication and Properties of Photoconductive Multilayer Using Se and $Sb_2S_3$ (Se와 $Sb_2S_3$를 이용한 광도전막의 제작과 그 특성)

  • 오상광;박기철;김건일;김기완
    • Journal of the Korean Institute of Telematics and Electronics
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    • v.24 no.4
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    • pp.646-651
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    • 1987
  • The photoconductive multilayer composed of glassy, porous, and fine-grained layers was fabdricated with Se and Sb2S3 by vacuum evaporation in order to be used as vidicon target. And its electrical, optical properties were investigatee. The fabrication conditions were as follow: the glassy layer was first deposited to have the thickness of 6500 \ulcornerat the deposition rate of 250\ulcornersec. High photosensitivity(\ulcorner=1) was obtained but its shortcoming was high dielectric constant. Therefore, the porous layer was added to lower dielectric constant and had 7500\ulcornerthick in the argon gas ambikent of 7x10-\ulcorner And the fine-grained layer was formed to prevent secondary electron emission and obtain good resolution. Its thickness was about 1700\ulcorner For the given vidicon target, the light transfer characteristic, that is, photosensitivity (\ulcorner) was measured to be 0.8 at the applied voltage of 25V. The spectral sensitivity was quite similar to that of the human eyes.

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Study on Mutual Relation between the Level of Deterioration Influenced by the Changes of Chemical and Physical Properties and the Change of Dielectric Constant for Engine Oil - Gasoline Engine Oil (엔진오일의 화학적 및 물리적 변화에 의한 퇴화정도와 유전상수 변화에 관한 상호관계 연구 - 가솔린엔진오일)

  • Chun, Sang-Myung
    • Tribology and Lubricants
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    • v.22 no.5
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    • pp.260-268
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    • 2006
  • The dielectric constants of used gasoline engine oils were obtained at a few temperatures and a frequency. Through analyzing the characteristics of dielectric constant, the related correlation between the changes in dielectric constants of oil and the degree of oil deterioration is going to be found. The dielectric constant was calculated using cross capacitances measured by a sensor tube. As results of the measurement of the fresh engine oil's dielectric constant, it was found that the value of dielectric constant was set down below $60^{\circ}C$ regardless changing frequency. Further, above 6 kHz, the dielectric constant was set down even if temperature was above $100^{\circ}C$ Therefore, for the measurement of used oils, it was selected the frequency of 6 kHz,,and the temperature of $80^{\circ}C$ preventing a certain ionic-conduction effects on the measured dielectric constant and the evaporation of a certain fluid mixed with engine oil. Specially, the effects of the mixing fluid like coolant, water and fuel on the fresh engine oil's dielectric constant were studied. It was found that the oil mixed with coolant showed the highest value, next water, and the lowest fuel. As results of the measurement of the used engine oil's dielectric constant, it was found that the possible changed rate of the used engine oil's dielectric constant based on the warning limit for engine oil in service was below 4% for gasoline engine oil.

Study on Mutual Relation between the Level of Deterioration Influenced by the Changes of Chemical and Physical Properties and the Change of Dielectric Constant for Engine Oil - Diesel Engine Oil (엔진오일의 화학적 및 물리적 변화에 의한 퇴화정도와 유전상수 변화에 관한 상호관계 연구 - 디젤엔진오일)

  • Chun, Sang-Myung
    • Tribology and Lubricants
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    • v.22 no.5
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    • pp.290-300
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    • 2006
  • The dielectric constants of used diesel engine oils were obtained at a few temperatures and a frequency. Through analyzing the characteristics of dielectric constant, the related correlation between the changes in dielectric constants of oil and the degree of oil deterioration is going to be found. The dielectric constant was calculated using cross capacitances measured by a sensor tube. As results of the measurement of the fresh engine oil's dielectric constant, it was found that the value of dielectric constant was set down below $60^{\circ}C$ regardless changing frequency. Further, above 6 kHz, the dielectric constant was set down even if temperature was above $100^{\circ}C$. Therefore, for the measurement of used oils, it was selected the frequency of 6 kHz, and the temperature of $80^{\circ}C$ preventing a certain ionic-conduction effects on the measured dielectric constant and the evaporation of a certain fluid mixed with engine oil. Specially, the effects of the mixing fluid like coolant, water and fuel on the fresh engine oil's dielectric constant were studied. It was found that the oil mixed with coolant showed the highest value, next water, and the lowest fuel. As results of the measurement of the used engine oil's dielectric constant, it was found that the possible changed rate of the used engine oil's dielectric constant based on the warning limit for engine oil in service was below 10% for diesel engine oil.

Desorption Characteristics of Volatile Organics Compounds in Soil by Microwave Heating (마이크로파 가열에 의한 토양 유기오염물질 탈착특성)

  • 문경환;김덕찬
    • Journal of environmental and Sanitary engineering
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    • v.11 no.2
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    • pp.65-73
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    • 1996
  • The objective of this study is to investigate the removal efficiency of volitile organic compounds in soil, and the mechanism of desorption by bench scale microwave heating, Silt soil used for experiment and was impregnated with toluene, tetrachloroethylene, o-xylene and p-dichlorobenzene and the microwave treatment was conducted in a modified domestic microwave oven : 2450MHz, 700W. According to the results of the research the removal efficiency was improved with increasing water contents and the soil temperature appeared to plateau period extending to 2-3minutes corresponds to the temperature a which steam distillation was expected. The value of removal rate constant (k) were calculated on dry and moisty silt soil, respectively, which showed linear with increasing microwave heating time. Therefore, addition of a certain amount of water to the contaminated soil can efficiently enhance the ability of the soil to absorb microwave energy and promote the evaporation of the volitile contaminants.

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Origin of Decreasing the Dielectric Constant and the Effect of Ionic Polarization (유전상수가 낮아지는 원인과 이온 분극의 효과)

  • Oh, Teresa
    • Journal of the Korean Vacuum Society
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    • v.18 no.6
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    • pp.453-458
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    • 2009
  • SiOC film was deposited by the chemical vapor deposition using BTMSM and oxygen mixed precursor. The characteristic of SiOC film varied with increasing of the gas flow rate ratios. The dielectric constant was obtained by C-V measurement using the structure of metal/SiOC film/Si. The space effect due to the steric hindrance between alkyl group at terminal bond of Si-$CH_3$ made the pores, and increased the thickness. However, the SiOC film due to the lowering of the polarization decreased the thickness and then decreased the dielectric constant. After annealing process, the dielectric constant decreased because of the evaporation of the OH or $H_2O$ sites. The thickness was related to the lowering of the dielectric constant by the reduction of the polarization and the thickness decreased with the decrease of the dielectric constant. The refractive index was in inverse proportion to thickness. The trends of the thickness and refractive index did not change after annealing.

Preparation and Characterization of Rosiglitazone-loaded PLGA Nanoparticles (Rosiglitazone약물을 함유한 PLGA 나노입자 제조 및 분석)

  • Shin, Ko-Eun;Huh, Kang-Moo;Lee, Yong-Kyu
    • KSBB Journal
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    • v.23 no.5
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    • pp.408-412
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    • 2008
  • The rosiglitazone loaded poly (lactide-co-glycolide) (PLGA) nanoparticles (NPs) were prepared by the emulsion-evaporation method and optimized for particle size and entrapment efficiency. The optimized particles were 140-180 nm in size with narrow size distribution and 80% entrapment efficiency at 1% w/w initial drug loading when prepared with 1-3% w/v of PVA as a surfactant. These particulate carriers exhibited controlled in vitro release of rosiglitazone for 36 hrs at a nearly constant rate after 4 hrs release. In conclusion, these results indicate that PLGA NPs have greater potential for oral delivery of rosiglitazone.

Development of the Novel Dry and Wet Deposition Collector (새로운 건성 및 습성 침착 채취기의 개발)

  • 이병규;이채복
    • Journal of Korean Society for Atmospheric Environment
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    • v.16 no.6
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    • pp.675-684
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    • 2000
  • A novel dry and wet deposition collector, which can overcome the several problems such as water evaporation cartridge cracks and high costs founded in the previous collector systems, has been constructed. ENVI-18 SPE adsorption cartridge has been used to measure atmospheric deposition of polycylic aromatic hydrocarbons (PAHs). A surrogate surface, consisted of water and methanol, was filled in the dry deposition funnel to simulate dry deposition onto water surface. A water supply system in order to compensat evaporation of the surrogate surface was used and it was consisted of a piston pump, a tubing pump, a overflow tube and a chamber system. A novel water vaporizing system to supply water onto the wet SPE cartridge system with a constant flow rate was developed. The novel water vaporizing system, consisted of a vacuum pump, a water supply reserviour and tube and a mini space heater, could prevent the PAHs adsorption cartridge cracks occurred in the previous collector and effectively adsorb PAHs. The novel dry and wet deposition collector showed a good adsorption, desorption, and recovery rates of PAHs. By reducing the number of pumps used and employing polypyopylene (PP) instead of teflon as a material of collection funnel, the total construction costs were much reduced as compared with the previous dry and wet deposition collectors.

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