• Toxicological Research
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• 제30권1호
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• pp.1-5
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• 2014

Xenograft models of human cancer play an important role in the screening and evaluation of candidates for new anticancer agents. The models, which are derived from human tumor cell lines and are classified according to the transplant site, such as ectopic xenograft and orthotopic xenograft, are still utilized to evaluate therapeutic efficacy and toxicity. The metastasis model is modified for the evaluation and prediction of cancer progression. Recently, animal models are made from patient-derived tumor tissue. The patient-derived tumor xenograft models with physiological characters similar to those of patients have been established for personalized medicine. In the discovery of anticancer drugs, standard animal models save time and money and provide evidence to support clinical trials. The current strategy for using xenograft models as an informative tool is introduced.

• 한국콘텐츠학회논문지
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• 제17권1호
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• pp.201-212
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• 2017

본 연구에서는 변동계수를 이용하여 DEA 모형의 변별력 평가에 적용할 수 있는 새로운 평가기준을 제시하였다. 변별력 평가를 위해 기존 연구에서 제시한 중요도와 본 연구에서 제안한 변동계수를 이용하여 변별력을 분석하였다. 다양한 DEA 모형들 중 변별력 평가를 위해 CCR-DEA, BCC-DEA, entropy, bootstrap, super efficiency, cross efficiency DEA 모형을 선정하고 실증분석을 실시하였다. 모형들의 순위상관관계를 파악하기 위해서 CCR 모형과 BCC 모형의 효율성 값과 entropy, bootstrap, super efficiency, cross efficiency 모형의 효율성 값들 간에 순위상관분석을 실시하였다. 본 연구를 통해 도출된 연구결과를 요약하면 다음과 같다. 첫째, 중요도와 변동계수를 이용한 모형들의 변별력 순위가 동일한 것으로 분석되어 변동계수를 DEA 모형의 변별력 평가기준으로 이용할 수 있다는 것이다. 둘째, 본 연구의 실증분석 결과에 따르면 4개 모형 중 super efficiency 모형이 변별력이 가장 높은 것으로 분석되었다. 셋째, CCR 모형과 순위상관관계가 가장 높은 모형은 super efficiency 모형으로 나타났고, BCC 모형과 순위상관관계가 가장 높은 모형도 super efficiency 모형으로 분석되었다.

• 대기
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• 제28권3호
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• pp.291-303
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• 2018

In this study, a new consensus technique for predicting tropical cyclone (TC) intensity in the western North Pacific was developed. The most important feature of the present consensus model is to select and combine the guidance numerical models with the best performance in the previous years based on various evaluation criteria and averaging methods. Specifically, the performance of the guidance models was evaluated using both the mean absolute error and the correlation coefficient for each forecast lead time, and the number of the numerical models used for the consensus model was not fixed. In averaging multiple models, both simple and weighted methods are used. These approaches are important because that the performance of the available guidance models differs according to forecast lead time and is changing every year. In particular, this study develops both a multi-consensus model (M-CON), which constructs the best consensus models with the lowest error for each forecast lead time, and a single best consensus model (S-CON) having the lowest 72-hour cumulative mean error, through on training process. The evaluation results of the selected consensus models for the training and forecast periods reveal that the M-CON and S-CON outperform the individual best-performance guidance models. In particular, the M-CON showed the best overall performance, having advantages in the early stages of prediction. This study finally suggests that forecaster needs to use the latest evaluation results of the guidance models every year rather than rely on the well-known accuracy of models for a long time to reduce prediction error.

• International Journal of Automotive Technology
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• 제7권5호
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• pp.595-601
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• 2006

Two No Spin Differential(NSD) models were benchmarked for a project of Dual-Use Technology. The Axiomatic approach is utilized to evaluate the designs of the models. The Independence Axiom is satisfied at the top level of design but not at the second level, which implies the design exhibits coupling and will admit design improvements. The detailed process of design evaluation is described. It is shown that it is possible to develop a unique and evolutionary NSD design by solving the problems that cause coupling within two models.

• 대한기계학회논문집A
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• 제29권7호
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• pp.947-954
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• 2005

The purpose of this study is to develop failure pressure evaluation models, which are applicable to straight pipes and elbows containing an internally wall thinning defect induced by flow-accelerated-corrosion (FAC). In this study, thus, three dimensional finite element (FE) analyses are performed to investigate the dependences of failure pressure of internally wall thinned pipe on the defect shape, the pipe geometry, and the defect location and bend radius of elbow. Also, the existing failure pressure assessment models for externally wall thinned pipes are examined. Based on these, the new models for assessing failure pressure of piping components with an internally wall thinning defect are proposed. Comparison of failure pressure, predicted by proposed models, with FE analysis result shows good agreement regardless of pipe type, defect shape, and defect location and bend radius.

• Communications for Statistical Applications and Methods
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• 제27권2호
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• pp.177-187
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• 2020

This article is concerned with the issue of forecasting and evaluation of threshold-asymmetric volatility models for time series of count data. In particular, threshold integer-valued models with conditional Poisson and conditional negative binomial distributions are highlighted. Based on the parametric bootstrap method, some evaluation measures are discussed in terms of one-step ahead forecasting. A parametric bootstrap procedure is explained from which directional measure, magnitude measure and expected cost of misclassification are discussed to evaluate competing models. The cholera data in Bangladesh from 1988 to 2016 is analyzed as a real application.

• 한국전산유체공학회지
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• 제10권4호통권31호
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• pp.1-11
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• 2005

A numerical study of the evaluation of turbulence models for thermal striping phenomenon is performed. The turbulence models chosen in the present study are the two-layer model, the shear stress transport (SST) model and the V2-f model. These three models are applied to the analysis of the triple-jet flow with the same velocity but different temperatures. The unsteady Reynolds-averaged Navier-Stokes (URANS) equation method is used together with the SIMPLEC algorithm. The results of the present study show that the temporal oscillation of temperature is predicted by the SST and V2-f models, and the accuracy of the mean velocity, the turbulent shear stress and the mean temperature is a little dependent on the turbulence model used. In addition, it is shown that both the two-layer and SST models have nearly the same capability predicting the thermal striping, and the amplitude of the temperature fluctuation is predicted best by the V2-f model.

• 경영과정보연구
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• 제9권
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• pp.117-137
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• 2002

As attention to the Internet from both companies and individuals is rapidly on the increase, hundreds of new websites are opening in a single day. Along with such a high attention to the Internet, to set up an effective website needs efficient evaluation and reliable evaluation criterions for the website. The existing homepage contests and evaluation models are limited to certain websites in a special field or to the systemic side and to the contents, which in fact weakened the development of detailed evaluation sections and items possibly measured. This study is designed to integrate and seek out methods and success factors that should be considered when a website is built up, discovering evaluation criterions and making evaluation models objectively possible to be measured. The study focused on investigation into a new measurement standard and model by considering the previous studies, in order to suggest the followings: Centering the 7 top evaluation sections by type of each website such as (1) Service, (2) Mechanism, (3) Structure & Navigation, (4) Usability, (5) Contents (6) Community, (7) Communication, the study suggests an objective and reasonable website evaluation model on a basis of common factors considered in an integral and optimum view.

• 산업공학
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• 제21권1호
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• pp.109-119
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• 2008

Reliability of embedded softwares, as one of factors which affect system reliability, is the probability of failure-free software operation for a specified period of time in a specified environment. and Embedded software is different from general package software because hardware and operating system are tightly coupled to each other. Reliability evaluation models for embedded softwares currently used do not separate estimation and prediction models clearly, and even a standard model has not been proposed yet. In this respect, we choose a reliability estimation model suitable for embedded softwares among software evaluation models being used, and modified the model so as to accomodate recent software environments. In addtion, based on the model, the web-based reliability prediction tool RPX is developed. Finally, an embedded software is analyzed using the tool.

• 산업공학
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• 제19권3호
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• pp.214-224
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• 2006

The container handling times of automated transfer cranes(ATCs) significantly affect the productivity of container terminals. In this paper, evaluation models for the container handling times of ATCs are suggested for import container blocks with different transfer point configurations. Firstly, evaluation models for various motion times of stacking and retrieving operations of ATC are suggested for two basic alternatives of import container blocks. In addition, in considering the space allocation, evaluation methods for the container handling times of ATC are suggested. Finally, the container handling times for each case are compared with each other in order to analyze how the block shape and the transfer point locations affect the container handling times of ATC.