Seo, Im-Ki;Choi, Jong-Tae;Park, Je-Jin;Park, Shin-Hyoung
KSCE Journal of Civil and Environmental Engineering Research
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v.35
no.2
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pp.417-426
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2015
The representative design elements of the road geometric structure are longitudinal slope, horizontal curve radius, super elevation, and transition curve. According to the function of a road, the design standards of these elements is applied by diverse combinations of them. This study divided expressway into homogeneous segments based on longitudinal slope and horizontal curve radius. And then, data required for analysis were matched to each segment, and the safety performance function was built by using the established data. crash modification factors which can explain traffic accident exposure rate were calculated. When the threshold value of horizontal curve radius R=1,000 m was set to 1.0, the crash modification factors at R=300 m was calculated as 1.33, which means that the accident exposure rate is increased by 33%. When the threshold value of the longitudinal slope 0% was set to 1.0, the crash modification factors demonstrated that the accident exposure rate decreases on the upward slope and the accident exposure rate increases on the downward slope. The results of this study can be used as basic information in the design of expressway geometries during the improvement or the construction of expressways.
To determine the relationship between comorbidity and outcome after radical cystectomy in Chinese patients by using the Adult Comorbidity Evaluation (ACE)-27 index. Two-hundred-and-forty-six patients treated with radical cystectomy at the Second Xiangya Hospital of Central South University, Hunan Province, China between 2000 and 2010 were retrospectively analyzed. Medical records were reviewed for age, gender, delayed time of radical cystectomy, urinary diversion type, pelvic lymphadenectomy status, TNM stage, and pathological grade. Comorbidity information was assessed by the ACE-27 index. The outcome measurement was overall survival. Univariate and multivariate Cox proportional hazards regression analyses were used to determine the association between comorbidity and outcome. The study population consisted of 215 (87.40%) males and 31 (12.60%) females with a mean age of $62{\pm}11$ years. Median duration of follow-up was $47{\pm}31$ months. A total of 151 (61.38%) patents died during follow-up. Of those, 118 (47.97%) had at least one comorbidity. According to the ACE-27 scores, 128 (52.03%) patients had no comorbidity, 79 (32.11%) had mild, 33 (13.41%) had moderate, and 6 (2.45%) had severe comorbidities. Multivariate analysis indicated that moderate (p=0.002) and severe (p<0.001) comorbidity was significantly associated with decreased overall survival. In addition, age ${\geq}70$ years (p=0.002), delayed time of radical cystectomy >12 weeks (p=0.044), pelvic lymphadenectomy status (p=0.014), and TNM stage >T3 (p<0.001) were determined to be independent risk factors of overall survival. Increasing severity of comorbidity statistically correlated with decreased overall survival after radical cystectomy.
Kim, Hyung-Jun;Yoon, Min-Seok;Park, Yong-Seok;Ha, Jin-Hwan;Jung, In-Kwon;Heu, Min-Soo;Kim, Jin-Soo
Journal of the Korean Society of Food Science and Nutrition
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v.37
no.11
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pp.1457-1464
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2008
For the effective use of under-utilized resources, silver-stripe round herring (SSRH), the plain-dried SSRH was investigated and compared with boiled-dried SSRH and boiled-dried anchovy on the food component and sensual characterization. Moisture content and salinity of the plain-dried SSRH were 31.9% and 7.6%, respectively. Moisture content of the plain-dried SSRH was higher, while the salinity was lower than those of boiled-dried SSRH and anchovy. According to the results of peroxide value, fatty acid composition, Hunter b value, and browning index, the rancidity was higher in plain-dried SSRH than in boiled-dried SSRH and anchovy. When compared to the boiled-dried SSRH and anchovy, the plain-dried SSRH was higher in calcium and phosphorus contents, while lower in total content of amino acid. According to the results of hot-water soluble-N, trichloroacetic acid-N, free amino acid, and taste value, the taste of plain-dried SSRH was superior to those of the boiled-dried SSRH and anchovy. The results of chemical components and sensory evaluation indicated that the plained-dried SSRH could be substituted for boiled-dried anchovy classified into special grade, if fish odor of SSRH can be improved.
Background: Many clinical trials have been conducted to evaluate sorafenib for the treatment of advanced NSCLC, but the results for efficacy have been inconsistent. The aim of this study was to evaluate the efficacy and safety of sorafenib in patients with advanced NSCLC in more detail by meta-analysis. Methods: This meta-analysis of randomized controlled trials (RCTs) was performed after searching PubMed, EMBASE, ASCO Abstracts, ESMO Abstracts, and the proceedings of major conferences for relevant clinical trials. Two reviewers independently assessed the quality of the trials. Outcomes analysis were disease control rate (DCR), progression- free survival (PFS), overall survival (OS) with 95% confidence intervals (CI) and major toxicity. Subgroup analysis was conducted according to sorafenib monotherapy, in combination with chemotherapy or EGFR-TKI to investigate the preferred therapy strategy. Results: Results reported from 6 RCTs involving 2, 748 patients were included in the analysis. Compared to sorafenib-free group, SBT was not associated with higher DCR (RR 1.31 (0.96- 1.79), p=0.09), PFS (HR 0.82 (0.66-1.02), p=0.07) and OS (HR 1.01 (0.92-1.12), p=0.77). In terms of subgroup results, sorafenib monotherapy was associated with significant superior DCR and longer PFS, but failed to show advantage with regard to OS. Grade 3 or greater sorafenib-related adverse events included fatigue, hypertension, diarrhea, oral mucositis, rash and HFSR. Conclusions: SBT was revealed to yield no improvement in DCR, PFS and OS. However, sorafenib as monotherapy showed some activity in NSCLC. Further evaluation may be considered in subsets of patients who may benefit from this treatment. Sorafenib combined inhibition therapy should be limited unless the choice of platinum-doublet regimen, administration sequence or identification of predictive biomarkers are considered to receive better anti-tumor activity and prevention of resistance mechanisms.
In order to clarify the lime-based building method used in the Joseon Dynasty, lime materials, production techniques, and mixing methods recorded in ancient literature were examined. In ancient Joseon Dynasty literature, the use of low grade limestone as a raw material was recorded, and the use of pozzolanic materials such as Hwangtoh, white clay, and roof tile powder as mixing aids to enhance the strength of lime was recorded. In addition, various lime hydration and mixing methods were recorded, and based on re-experiments carried out with regards to this, a physical property evaluation was deemed to be required in accordance with the various types of raw lime materials, lime hydration methods, and mixture ratios. In the early Joseon Dynasty, lime was used for various aspects, but frequent problems were experienced due to lack of supply and poor production techniques. In the late Joseon Dynasty, lime production techniques developed along with mass production. Based on analysis of the manufacturing techniques of Hoegwagmyo lime mortar in the 16th and 18th centuries during the Joseon Dynasty, it was found that mixing ratios and the methods described in the ancient literature had been applied. It was confirmed that the mixing ratio differed depending on mixing materials and lime quality. Since the mixing ratio of Hoegwagmyo lime mortar changed over time and it was produced strictly on the basis of a guidebook, it is believed that if continuous scientific analysis of the Hoegwagmyo lime mortar production method were carried out, this would be helpful for ascertaining the chronological methodology of Hoegwagmyo.
Rice quality is considered to have two general meanings; 1) milling, cooking, and processing quality, which refer to suitability of the grain for a particular end-use; and 2) physical quality, which means cleanliness, soundness, and freedom from foreign materials. Grain type is associated with specific milling, cooking, and processing characteristics. Thus, this experiment was conducted to classify the grain type categories and marketing grades for Korean leading rice varieties. Length: width ratio of brown rice kernel ranged from 1.57 to 2.25 and most of varieties belonged to short grain except Tongil type rice varieties. Mean of length: width ratio of brown rice kernel was 1.77 and coefficient of variance was 4.79% in short grain type varieties. Grain shape could be further classified into 5 types by length:width ratio of brown rice kernel; 1 type(less than 1.75), 2 type(1.76∼1.80), 3 type(1.81∼1.90), 4 type(1.91∼2.00), and 5 type (greater than 2.00). For 1 and 2 type of varieties, woven wire sieve having 1.7mm openings showed better whole-kernel yields for special marketing grade, and sieve having 2.0mm openings for 3 and 4 type of varieties. Grain type which classified into 5 categories was not associated with physicochemical and cooking characteristics of rice grain, but sensory evaluation of cooked rice showed better score for 1 type varieties in terms of appearance, gloss, flavor, texture, stickiness, and taste.
This study aims to grasp the general conditions regarding university students in security related majors in Korea. Followings will be covered here: what motivated them to choose those majors, hw much are they git jobs through the education, what is their conscioucness on their majors, jobs, and courses like, and what effects their job preference. And ths study also aims at helping the student with their future plans such as admission to a school of higher grade and choosing their job. For this study, we distributed 340 copies to the students in security related majors at 4 four-year colleges and 1 two-year college, and collected 298 copies by means of quota sampling method. For collected questionnaires, we used individual T-test verification and one-way ANOVA analysis to grasp the situation. Significance stabdard for the test results was set as p<0.05. Followings are the test results. The results on analysis of satisfaction rate on their curriculums, classes, and majors show that students in security-related majors showed different satisfaction rate and different averages according to their sex and the year of the college. In the analysis on the relationship between major education and employment of students in security-related majors, the result of curriculum improvement and scholaril attainments analysis showed statistically significant relation. When students in security-related majors were surveyed on their consciousness of their future plans such as getting jibs, two-year college students had more certificates of qualification for employment than four-year college students.
Objective : We retrospectively analysed $^{99m}Tc$-MDP bone and $^{67}Ga$ scans to evaluate therapeutic response of bone lymphoma among patients with complete remission. Subjects and Methods : We reviewed 35 cases with an increased uptake finding $^{99m}Tc$-MDP bone scans and 16 $^{67}Ga$ scans that were follow-up studies during and after therapy. The $^{99m}Tc$-MDP bone and $^{67}Ga$ scans were graded visually from 1 to 4 in which grade 3 means same uptake density as that of normal sacroiliac articulation in bone scan and normal liver in $^{67}Ga$ scan, respectively. Results: The improvement findings during and after therapy were found in 66.0% (19/ 29) and 72.7% (24/33) with $^{99m}Tc$-MDP bone scan, 84.6% (l1/13) and 86.7% (13/15) with $^{67}Ga$ scan, respectively. The mean grades of the uptake density in $^{99m}Tc$-MDP bone scan were 3.06 before, 2.34 during, 1.75 after therapy. Those in the $^{67}Ga$ scan were 3.22 before, 1.42 during 1.30 after therapy. Conclusion. $^{67}Ga$ scans appeared more sensitive than bone scans in evaluating therapeutic response of bone lymphoma.
This study is aimed to emphasize the significance of ore selection in lime manufacturing through the evaluation of applied-mineralogical impact factors of crude ores controlling calcination characteristics for some domestic limestones used currently for lime manufacturing. To do this work, systematic characterization and determination were carried out for the limestone ores and their calcination products in a fixed calcining condition (target temperature: $1000^{\circ}C$, retention time: 30 minutes, 2, 4, 10, 16 hours), and the results were correlated and discussed. Selected high-Ca limestones in this study are as much as > 98 wt%, but they are somewhat diverse in crystallinity, texture, and impurity composition. Synthesized quicklimes are varied depending on such a difference in ore characters. The Pungchon limestone has relatively very low calcination rate, and the limestones from the Gabsan formation and the Jeongseon formation exhibit good quality in calcination rate and decrepitation. Among these samples, the limestone ore from the Jeongseon formation is evaluated to be the best for crude ore in manufacturing of highly-reactive quicklime. In addition, it is characteristic that the Gabsan limestone comparative rich in Fe-bearing mineral such as pyrite and goethite is more conspicuous in sintering effect.
The purpose of this study was to investigate the effect of peer tutoring on mathematical inclination and mathematical communication ability of peer tutor. For the purpose of this study, research questions were established as follows: 1. How does peer tutoring affect to the mathematical inclination of peer tutors? 2. How does peer tutoring affect to the mathematical communication ability of peer tutors? To answer the research questions, four 5th grade peer tutors were selected for qualitative case study in an elementary school located in Goyang-si, Gyeonggi-do. Before and after 11 weeks of peer tutoring in their mathematics classes, mathematical inclination, mathematical communication ability of peer tutors were examined. For qualitative analysis, peer tutors were asked to complete worksheets, self-evaluation, journal for their peer tutoring in daily basis during the experiment. By comparing the scores in mathematical inclination test and mathematical communication test before and after the treatment and analyzing the data gathered for qualitative analysis, the conclusions were drawn as follows: First, Peer tutoring has positive effects on the mathematical inclination of peer tutors. Scores for mathematical inclination of peer tutors after the treatment increased and qualitative analysis showed positive change in their attitude toward mathematics. Second, Peer tutoring has positive effects on the mathematical communication ability of peer tutors. Scores in the performance assessment for mathematical communication ability of peer tutors after the treatment increased. Also qualitative analysis showed that peer tutors tried to develop various ways to solve a problem and explained them to their peer tutee sophisticatedly.
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