• Journal of Digital Convergence
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• v.12 no.11
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• pp.395-405
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• 2014

This study tends to grasp the physical activity on its influences and effect s to the mental health of middle school students and we tried to look for a specific plan that will help to improve middle school students' mental health. We analyzed 36,530 students in middle school using a basic data "9th (2013) health behavior of juvenile on the online". The study is analyzed by complex sample data analysis method. The degree of euphoria recognition showed the low feeling of happiness when students exercise directly below two times rather than three times a week in the Physical Education class at school. On the other hand, the possibility of stress perception degree and suicide attempt is lowered. If the number of sports team participating is below one team, euphoria would be lowered and the limit of stress perception is high. However, the participation of one or two teams make the possibility of suicide lessens rather than students taking part in more 4 teams. In order to help middle school students reduce their stress and improve their happiness, they need to participate in sports as a regular team and join intramural games more than three times a week. In this case of the lower grade, it is considered that it is necessary for them to combine the educational program for the emotional support to control their extreme behavior.

• YAKHAK HOEJI
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• v.44 no.1
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• pp.22-28
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• 2000

The extracts of Euphoria longan, Ziryphus jujuba, Thuja orientalis, Polygala tenuifolia, Acorus gramineus, Cyperus rotundus, Poria cocos, Uncaria rhynchophylla, and Albizzia julibrissin, which have been used as sedative drugs in Korean folk medicine, were evaluated for their effects on neurotransmission and antioxidative system in vitro. Among the tested drugs, Acorus gramineus showed most inhibitory activities on monoamine oxidase, xanthine oxidase, aldehyde oxidase, and lipid peroxidation and Uncaria rhynchophylla also inhibited most effectively GABA transaminase and DPPH radical.

• Maxillofacial Plastic and Reconstructive Surgery
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• v.30 no.1
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• pp.114-116
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• 2008

Mania in psychiatry describes not only the state of temporary elation of the mood but also of the general mental function such as contents of a thought, thinking process, motivation, enthusiasm, interest, behavior, slumber and physical activities. The time of period when the above changes of mood, mental and behavioral disorder appear is called a manic episode. Postoperative mania is very rare and it has been reported only 5 times in english literature. It's an extremely rare case which has not yet been reported in Oral and Maxillofacial surgery. Patients normally deny the symptoms and it is easy to miss the diagnosis since the patient tends to seem content and happy. Patients show the following initial symptoms of mania - postoperative insomnia, atypical gregariousness, euphoria and unstability. Patients who are not disaffected with insomnia can also be included.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1996.11a
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• pp.171-172
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• 1996

Cocaine is a powerful reinforcer that has become a popular drug of abuse in man. CNS effects that are related to the abuse of cocaine include feeling of well-being and euphoria. Brain dopamine systems are thought to mediate reinforcement and it is often assumed that cocaine's inhibition of dopamine uptake is the mechanism underlying its reinforcing effects. With increase in cocaine use among general population in recent years, adverse effects of the drug have occurred in all social strata and age groups. Therefore, it has been recognized that the epidemic of cocaine abuse is a growing major concerning public health. One of the most troubling aspects of cocaine abuse is its use by pregnant women. Drug abuse during pregnancy puts two lives at risk. Cocaine produces toxic effects on the fetus at concerntrations that are apparently nontoxic to the mother. Not only does cocaine cross the placenta via diffusion and via rapid penetration to mucous membranes, due to its high lipid solubility, but cocaine can also be found in breast milk, the effects of the cocaine can persist long after the child is born. Although it is known that prenatal cocaine exposure is associated with developmental risk to the fetus ana newborn, few studies have been conducted to assess the mechanisms whereby either short-term or long-term administration of cocaine can exert its harmful effects on the mother or the child. Therefore, it was our great interest to investigate the pharmacological and neurobehavioral changes in offspring that are prenatally exposed to cocaine.

• Journal of Life Science
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• v.10 no.4
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• pp.374-379
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• 2000

This study was attempted to evaluate an agonistic activity to benzodiazepine receptor of several medicinal pants, which have been used as sedatives in oriental medicine. The activities of the methanol extracts of composite preparation of oriental drugs were compared with those of the simple drugs, furthermore, the active fraction was found out from the simple preparation. Inhibitory effects of composite preparations, Cyperus rotundus/Acorus gramineus, Thuja orientalis/Euphoria longan, Thuja orientalis/Albizzia julibrissin, on the binding of ${[^3H]}$Ro15-1788, a selective benszodiazepine receptor antagonist to benzodiazepine receptor of rat cortices, were observed to be lower than those of corresponding simple preparations. These unexpected results suggest that some components of the composite druge may rather act as an obstacle, not to show the sinergistic effect. The methanol extracts of Cyperus rotundus having the highest activity were fractionated using polar and nonpolar solvents to give ethylacetate and hexane fractions, respectively. The ethylacetate fraction containing relatively polar components exhibited much higher activity than the hexane fraction, which consiste of nonpolar agonist, binding to benzodiazepine receptor. However, in the presence of GABA, this fraction inhibited ${[^3H]}$flunitrazepan binding, and these positive GABA shift supported the strong possibility of agonistic activity to benzodiazepine receptro. As a result, it may be concluded that the substance or substances with neurochemical properties as a benzodiazepine receptor agonist may contribute to the sedative property of Cyperus rotundus.

• Research in Community and Public Health Nursing
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• v.12 no.1
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• pp.261-268
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• 2001

Recently, social concerns about addiction problems not only to substances like alcohol and drug but also to gambling or internet have been increasing. Addiction is caused by a combined influence of biological, psychological. and social factors. However, addiction may also occur due to weak will-power or poor education on addiction. Even though addicted behavior provides temporal mood change such as euphoria, satisfaction. or relaxation. it leads to serious physical and mental disorder of the addicted person and its family members, which possibly results in fatal consequences. Nurses are in an environment to meet and take care of those who are addicted or vulnerable to addiction in order to help the clients to recover or to prevent people from addiction. Despite the importance of nurses role in addiction problems, there is a lack of consistency of addiction is often interchangeably used with other similar concepts in the society. In this study, a concept analysis of addiction was performed to more clearly and comprehensively understand addiction and to develop effective nursing intervention methods for addicted clients. The analysis is conducted according to a series of processes described by Walker and Avant. The defining attributes of addiction identified in this study are as follows: 1) existence of object 2) control loss 3) withdrawal symptoms 4) continued use despite adverse consequences.

• Journal of Integrative Natural Science
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• v.16 no.3
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• pp.75-80
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• 2023

Bipolar disorder is a mental illness characterized by extreme mood and behavioral swings, such as highs of euphoria and lows of depression. It is a socially significant disorder in which people with the disorder experience intense mood swings and, for those with severe bipolar disorder, it is even difficult leading a normal life. High stress levels in people with mental illness can lead to neuroendocrine disruption, and it is strongly linked to aging. When the neuroendocrine system becomes vulnerable to these mental illnesses and stress, it is likely to accelerate aging. And it's the epigenetic clock that can measure the extent of this accelerated aging. The Epi clock, a pan tissue clock, measures aging through DNA methylation, and the degree of methylation is modified and changed by environmental conditions in the body. Therefore we wanted to check the changes in the epigenetic age of the patients with bipolar disorder. While we found no significant differences in epigenetic age, we did confirm the possibility that people with bipolar disorder have different methylation than normal people. We also found that the EPIC array data fit better on the Epi clock than on the Horvath clock with age-accelerated data from normal people.

• Journal of Digital Convergence
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• v.15 no.8
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• pp.247-256
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• 2017

The purpose of this study was to identify the convergent influence of social awareness and health status on social support in Korean echo generation by using Korea adult psycho-social anxiety survey data. Korea adult psycho-social anxiety survey data were collected from August to September 2015 and included 1,653, who responded to the question regarding social support. The data were analyzed by t-test, chi-square and hierarchial multiple regression using SPSS WIN 23.0 program. The mean score of social support was 19.60. The influencing factors on social support were neighborhood relations, perceived class, euphoria, equality in society, stability in society, self Esteem, communication, and stress, respectively. Therefore, it is necessary to establish strategies to strengthen social support of echo generation. A more careful examination may be warranted.

• Journal of Physiology & Pathology in Korean Medicine
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• v.25 no.3
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• pp.406-416
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• 2011

In this study, we have verified the memory and cognitive enhancing effect of Longanae Arillus, the fruit of Euphoria longana Lamarck, which has been used as a tonic and for the treatment of amnesia, insomnia, and palpitations in oriental medicine. To investigate the effect of Longanae Arillus water extract(LAE) on the memory and cognitive dysfunction, scopolamine (1 mg/kg, i.p.) was injected in C57BL/6 mice and several behavior tests including Y-maze, Morris water-maze, passive avoidance and fear conditioning tests were conducted. Administration of LAE (100 or 200 mg/kg/day, p.o.) effectively improved scopolamine-induced memory impairment and dysfunction. To further determine the possible molecule mechanism of LAE, we have examined the activity and/or mRNA expression of diverse proteins involved in the acetylcholine metabolism. LAE particularly increased the amount of acetylcholine in the cortex which was mediated by suppression of acetylcholine esterase (AchE) activity. In addition, LAE elevated the mRNA expression of muscarinic acetylcholine receptors (mAchRs) without affecting the mRNA levels of choline acetyltransferase (ChAT) and acetylcholine esterase (AchE). In another experiment, LAE effectively inhibited mRNA expression of pro-inflammatory cytokines such as tumor necrosis factor-${\alpha}$ (TNF-${\alpha}$) and interleukin-$1{\beta}$ (IL1-${\beta}$), which seemed to be mediated by inhibition of upstream transcription factor NF-${\kappa}B$ and extracellular-regulated kinase 1/2 (ERK1/2). These results demonstrate that Longanae Arillus can increase acetylcholine amount the cortex via regulation of AchE activity as well as mAchRs expression and decrease pro-inflammatory responses via inhibition of NF-${\kappa}B$ signaling pathway, thereby having therapeutic potential to improve memory and cognitive deficit in amnesia.

• The Journal of the Korea Contents Association
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• v.20 no.1
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• pp.684-691
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• 2020

This study was attempted to provide basic data for health promotion program for depressive relief by grasping the degree of depression of adult women and grasping the factors affecting depression. Data were collected using structured questionnaire for 249 adult women in the one marine city and analyzed through technical statistics, Pearson correlation coefficients and multiple regression analysis. According to the study, 76.3 percent (190 people) of women in the city were depressed. The subjects who expressed depression showed negative correlations with social support, self-respect and subjective euphoria and between depression and stress as positive correlation. The result of multiple regression analyses to identify the effects of depression have shown that stress is a major influencing factor, and this model has a 21.1% explanatory power. Therefore, the study found stress as a significant factor in the depression of adult women, it is necessary to develop and apply health promotion programs that can reduce stress in order to reduce depression in adult women.